Industrial Pharmaceutical Biotechnology

Industrial Pharmaceutical Biotechnology PDF Author: Heinrich Klefenz
Publisher: Wiley-VCH
ISBN:
Category : Medical
Languages : de
Pages : 328

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Book Description
This volume focuses on pharmaceutical biotechnology as a key area of life sciences. The complete range of concepts, processes and technologies of biotechnology is applied in modern industrial pharmaceutical research, development and production. The results of genome sequencing and studies of biological-genetic function are combined with chemical, micro-electronic and microsystem technology to produce medical devices and diagnostic biochips. A multitude of biologically active molecules is expanded by additional novel structures created with newly arranged gene clusters and bio-catalytic chemical processes. New organisational structures in the co-operation of institutes, companies and networks enable faster knowledge and product development and immediate application of the results of research and process development. This book is the ideal source of information for scientists and engineers in research and development, for decision-makers in biotech, pharma and chemical corporations, as well as for research institutes, but also for founders of biotech companies and people working for venture capital corporations.

Industrial Pharmaceutical Biotechnology

Industrial Pharmaceutical Biotechnology PDF Author: Heinrich Klefenz
Publisher: Wiley-VCH
ISBN:
Category : Medical
Languages : de
Pages : 328

Get Book Here

Book Description
This volume focuses on pharmaceutical biotechnology as a key area of life sciences. The complete range of concepts, processes and technologies of biotechnology is applied in modern industrial pharmaceutical research, development and production. The results of genome sequencing and studies of biological-genetic function are combined with chemical, micro-electronic and microsystem technology to produce medical devices and diagnostic biochips. A multitude of biologically active molecules is expanded by additional novel structures created with newly arranged gene clusters and bio-catalytic chemical processes. New organisational structures in the co-operation of institutes, companies and networks enable faster knowledge and product development and immediate application of the results of research and process development. This book is the ideal source of information for scientists and engineers in research and development, for decision-makers in biotech, pharma and chemical corporations, as well as for research institutes, but also for founders of biotech companies and people working for venture capital corporations.

Handbook of Plant Ecophysiology Techniques

Handbook of Plant Ecophysiology Techniques PDF Author: M. J. Reigosa Roger
Publisher: Springer Science & Business Media
ISBN: 0306480573
Category : Science
Languages : en
Pages : 450

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Book Description
The Handbook of Plant Ecophysiology Techniques you have now in your hands is the result of several combined events and efforts. The birth of this handbook can be traced as far as 1997, when our Plant Ecophysiology lab at the University of Vigo hosted a practical course on Plant Ecophysiology Techniques. That course showed us how much useful a handbook presenting a bunch of techniques would be for the scientists beginning to work on Plant Ecophysiology. In fact, we wrote a short handbook explaining the basics of the techniques taught in that 1997 course: Flow cytometry to measure ploidy levels, Use of a Steady-State porometer to measure transpiration, In vivo measure of fluorescence, HPLC analysis of low molecular weight phenolics, Spectrophotometric determinations of free proline and soluble proteins, TLC polyamines contents measures, Isoenzymatic electrophoresis, Use of IRGA and oxygen electrode. That modest handbook, written in Spanish, was very helpful, both for the people who attended the course and for other who have used it for beginning to work in Plant Ecophysiology. The present Handbook is much more ambitious, and it includes more techniques. But we have also had in mind the young scientists beginning to work on Plant Ecophysiology. In 1999 François Pellissier leaded a proposal presented to the European Commission in the Fifth Framework Program in the High Level * Scientific Conferences, including three EuroLab Courses about lab and field techniques useful to improve allelopathic research.

Chromosome Painting

Chromosome Painting PDF Author: Arun Kumar Sharma
Publisher: Springer Science & Business Media
ISBN: 9401003300
Category : Science
Languages : en
Pages : 179

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Book Description
Chromosome Painting is the most modern and novel technique for directly identifying several gene sequences simultaneously in the chromosome, with the aid of specific probes in molecular hybridization. Its resolution ranges from single copy to entire genome sequences. It is now applied in plant, animal, and human systems, in gene mapping, identification of genetic disorders, evolutionary studies, and gene transfer experiments. This treatise is the first of its kind to cover the technique with all its modifications and applications. It is designed for regular use by postgraduate students and research workers in cell and molecular genetics, plant and animal sciences, agriculture, medicine, and phylogenetic studies.

Brain, Body and Machine

Brain, Body and Machine PDF Author: Jorge Angeles
Publisher: Springer Science & Business Media
ISBN: 3642162592
Category : Technology & Engineering
Languages : en
Pages : 364

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Book Description
The reader will find here papers on human-robot interaction as well as human safety algorithms; haptic interfaces; innovative instruments and algorithms for the sensing of motion and the identification of brain neoplasms; and, even a paper on a saxophone-playing robot.

Handbook of Microalgae-Based Processes and Products

Handbook of Microalgae-Based Processes and Products PDF Author: Eduardo Jacob-Lopes
Publisher: Academic Press
ISBN: 0128185376
Category : Technology & Engineering
Languages : en
Pages : 938

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Book Description
The Handbook of Microalgae-based Processes and Products provides a complete overview of all aspects involved in the production and utilization of microalgae resources at commercial scale. Divided into four parts (fundamentals, microalgae-based processes, microalgae-based products, and engineering approaches applied to microalgal processes and products), the book explores the microbiology and metabolic aspects of microalgae, microalgal production systems, wastewater treatment based in microalgae, CO2 capture using microalgae, microalgae harvesting techniques, and extraction and purification of biomolecules from microalgae. It covers the largest number of microalgal products of commercial relevance, including biogas, biodiesel, bioethanol, biohydrogen, single-cell protein, single-cell oil, biofertilizers, pigments, polyunsaturated fatty acids, bioactive proteins, peptides and amino acids, bioactive polysaccharides, sterols, bioplastics, UV-screening compounds, and volatile organic compounds. Moreover, it presents and discusses the available engineering tools applied to microalgae biotechnology, such as process integration, process intensification, and techno-economic analysis applied to microalgal processes and products, microalgal biorefineries, life cycle assessment, and exergy analysis of microalgae-based processes and products. The coverage of a broad range of potential microalgae processes and products in a single volume makes this handbook an indispensable reference for engineering researchers in academia and industry in the fields of bioenergy, sustainable development, and high-value compounds from biomass, as well as graduate students exploring those areas. Engineering professionals in bio-based industries will also find valuable information here when planning or implementing the use of microalgal technologies. - Covers theoretical background information and results of recent research. - Discusses all commercially relevant microalgae-based processes and products. - Explores the main emerging engineering tools applied to microalgae processes, including techno-economic analysis, process integration, process intensification, life cycle assessment, and exergy analyses.

Medicines from Animal Cell Culture

Medicines from Animal Cell Culture PDF Author: Glyn N. Stacey
Publisher: John Wiley & Sons
ISBN: 9780470723784
Category : Science
Languages : en
Pages : 696

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Book Description
Medicines from Animal Cell Culture focuses on the use of animal cell culture, which has been used to produce human and veterinary vaccines, interferon, monoclonal antibodies and genetically engineered products such as tPA and erythropoietin. It also addresses the recent dramatic expansion in cell-based therapies, including the use of live cells for tissue regeneration and the culture of stem cells. Medicines from Animal Cell Culture: Provides comprehensive descriptions of methods for cell culture and nutrition as well as the technologies for the preservation and characterisation of both the cells and the derived products Describes the preparation of stem cells and others for use in cell-based therapies – an area of burgeoning research Includes experimental examples to indicate expected results Covers regulatory issues from the UK, the EU and the USA and reviews how these are developing around the world Addresses the key issues of standardisation and validation with chapters on GLP and GMP for cell culture processes Delivering insight into the exciting world of biological medicines and directions for further investigation into specific topics, Medicines from Animal Cell Culture is an essential resource for researchers and technicians at all levels using cell culture within the pharmaceutical, biotechnology and biomedical industries. It is of value to laboratory managers in these industries and to all those interested in this topic alike.

FISH Technology

FISH Technology PDF Author: Bernd W. Rautenstrauß
Publisher: Elsevier
ISBN: 9783540672760
Category : Medical
Languages : en
Pages : 508

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Book Description
Fluorescence in situ hybridization (FISH) has been developed as a powerful technology which allows direct visualisation or localisation of genomic alterations. The technique has been adopted to a range of applications in both medicine, especially in the areas of diagnostic cytogenetics, and biology. Topics described in this manual include: FISH on native human tissues, such as blood, bone marrow, epithelial cells, hair root cells, amniotic fluid cells, human sperm cells; FISH on archival human tissues, such as formalin fixed and paraffin embedded tissue sections, cryofixed tissue; simultaneous detection of apoptosis and xpression of apoptosis-related genes; comparative genomic ybridization; and special FISH techniques.

Small Supernumerary Marker Chromosomes (sSMC)

Small Supernumerary Marker Chromosomes (sSMC) PDF Author: Thomas Liehr
Publisher: Springer Science & Business Media
ISBN: 3642207669
Category : Medical
Languages : en
Pages : 233

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Book Description
Human beings normally have a total of 46 chromosomes, with each chromosome present twice, apart from the X and Y chromosomes in males. Some three million people worldwide, however, have 47 chromosomes: they have a small supernumerary marker chromosome (sSMC) in addition to the 46 normal ones. This sSMC can originate from any one of the 24 human chromosomes and can have different shapes. Approximately one third of sSMC carriers show clinical symptoms, while the remaining two thirds manifest no phenotypic effects. This guide represents the first book ever published on this topic. It presents the latest research results on sSMC and current knowledge about the genotype-phenotype correlation. The focus is on genetic diagnostics as well as on prenatal and fertility-related genetic counseling. A unique feature is that research meets practice: numerous patient reports complement the clinical aspects and depict the experiences of families living with a family member with an sSMC.

A Textbook of Practical Physiology

A Textbook of Practical Physiology PDF Author: CL Ghai
Publisher: JP Medical Ltd
ISBN: 935025932X
Category : Medical
Languages : en
Pages : 410

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Book Description


Carnosine and Oxidative Stress in Cells and Tissues

Carnosine and Oxidative Stress in Cells and Tissues PDF Author: Alexander A. Boldyrev
Publisher: Nova Publishers
ISBN: 9781600214110
Category : Medical
Languages : en
Pages : 312

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Book Description
The main aim of this new book is to summarise the knowledge on the metabolic transformation of carnosine in excitable tissues of animals and human beings and to analyse the nature of its biological activity. At the beginning of monograph, the short history of the problem is stated. Distribution of carnosine in tissues, its appearance in ontogeny of vertebrates and correlation between carnosine content and functional activity of tissues are discussed. Chemical properties of carnosine and its natural derivatives and their ability to bind heavy metals and protons in water solution are documented. Special attention is paid to free radical quenching ability and to anti-glycating action. Biological activity of carnosine and carnosine containing compounds was tested using biological models of several levels of complexity, starting from individual enzymes and acellular mixtures and finishing to living cells and survival animals. Effects of carnosine on the whole animals under ischemic, hypoxic and other extreme conditions are described. In conclusion, the ability of carnosine to protect brain and muscular tissues from oxidative injury during exhausting exercise, extreme loading or neurodegenerative diseases is demonstrated. Based on these properties, carnosine is postulated to be a potent protector of human beings from oxidative stress.