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Author: Nick Lane
Publisher: OUP Oxford
ISBN: 9780191513015
Category : Science
Languages : en
Pages : 370
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Book Description
Mitochondria are tiny structures located inside our cells that carry out the essential task of producing energy for the cell. They are found in all complex living things, and in that sense, they are fundamental for driving complex life on the planet. But there is much more to them than that. Mitochondria have their own DNA, with their own small collection of genes, separate from those in the cell nucleus. It is thought that they were once bacteria living independent lives. Their enslavement within the larger cell was a turning point in the evolution of life, enabling the development of complex organisms and, closely related, the origin of two sexes. Unlike the DNA in the nucleus, mitochondrial DNA is passed down exclusively (or almost exclusively) via the female line. That's why it has been used by some researchers to trace human ancestry daughter-to-mother, to 'Mitochondrial Eve'. Mitochondria give us important information about our evolutionary history. And that's not all. Mitochondrial genes mutate much faster than those in the nucleus because of the free radicals produced in their energy-generating role. This high mutation rate lies behind our ageing and certain congenital diseases. The latest research suggests that mitochondria play a key role in degenerative diseases such as cancer, through their involvement in precipitating cell suicide. Mitochondria, then, are pivotal in power, sex, and suicide. In this fascinating and thought-provoking book, Nick Lane brings together the latest research findings in this exciting field to show how our growing understanding of mitochondria is shedding light on how complex life evolved, why sex arose (why don't we just bud?), and why we age and die. This understanding is of fundamental importance, both in understanding how we and all other complex life came to be, but also in order to be able to control our own illnesses, and delay our degeneration and death. 'An extraordinary account of groundbreaking modern science... The book abounds with interesting and important ideas.' Mark Ridley, Department of Zoology, University of Oxford
Author: Nick Lane
Publisher: OUP Oxford
ISBN: 9780191513015
Category : Science
Languages : en
Pages : 370
Get Book Here
Book Description
Mitochondria are tiny structures located inside our cells that carry out the essential task of producing energy for the cell. They are found in all complex living things, and in that sense, they are fundamental for driving complex life on the planet. But there is much more to them than that. Mitochondria have their own DNA, with their own small collection of genes, separate from those in the cell nucleus. It is thought that they were once bacteria living independent lives. Their enslavement within the larger cell was a turning point in the evolution of life, enabling the development of complex organisms and, closely related, the origin of two sexes. Unlike the DNA in the nucleus, mitochondrial DNA is passed down exclusively (or almost exclusively) via the female line. That's why it has been used by some researchers to trace human ancestry daughter-to-mother, to 'Mitochondrial Eve'. Mitochondria give us important information about our evolutionary history. And that's not all. Mitochondrial genes mutate much faster than those in the nucleus because of the free radicals produced in their energy-generating role. This high mutation rate lies behind our ageing and certain congenital diseases. The latest research suggests that mitochondria play a key role in degenerative diseases such as cancer, through their involvement in precipitating cell suicide. Mitochondria, then, are pivotal in power, sex, and suicide. In this fascinating and thought-provoking book, Nick Lane brings together the latest research findings in this exciting field to show how our growing understanding of mitochondria is shedding light on how complex life evolved, why sex arose (why don't we just bud?), and why we age and die. This understanding is of fundamental importance, both in understanding how we and all other complex life came to be, but also in order to be able to control our own illnesses, and delay our degeneration and death. 'An extraordinary account of groundbreaking modern science... The book abounds with interesting and important ideas.' Mark Ridley, Department of Zoology, University of Oxford
Author: Nick Lane
Publisher: Oxford University Press
ISBN: 0191639079
Category : Science
Languages : en
Pages : 385
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Book Description
Oxygen has had extraordinary effects on life. Three hundred million years ago, in Carboniferous times, dragonflies grew as big as seagulls, with wingspans of nearly a metre. Researchers claim they could have flown only if the air had contained more oxygen than today - probably as much as 35 per cent. Giant spiders, tree-ferns, marine rock formations and fossil charcoals all tell the same story. High oxygen levels may also explain the global firestorm that contributed to the demise of the dinosaurs after the asteroid impact. The strange and profound effects that oxygen has had on the evolution of life pose a riddle, which this book sets out to answer. Oxygen is a toxic gas. Divers breathing pure oxygen at depth suffer from convulsions and lung injury. Fruit flies raised at twice normal atmospheric levels of oxygen live half as long as their siblings. Reactive forms of oxygen, known as free radicals, are thought to cause ageing in people. Yet if atmospheric oxygen reached 35 per cent in the Carboniferous, why did it promote exuberant growth, instead of rapid ageing and death? Oxygen takes the reader on an enthralling journey, as gripping as a thriller, as it unravels the unexpected ways in which oxygen spurred the evolution of life and death. The book explains far more than the size of ancient insects: it shows how oxygen underpins the origin of biological complexity, the birth of photosynthesis, the sudden evolution of animals, the need for two sexes, the accelerated ageing of cloned animals like Dolly the sheep, and the surprisingly long lives of bats and birds. Drawing on this grand evolutionary canvas, Oxygen offers fresh perspectives on our own lives and deaths, explaining modern killer diseases, why we age, and what we can do about it. Advancing revelatory new ideas, following chains of evidence, the book ranges through many disciplines, from environmental sciences to molecular medicine. The result is a captivating vision of contemporary science and a humane synthesis of our place in nature. This remarkable book will redefine the way we think about the world.
Author: Nick Lane
Publisher: Profile Books
ISBN: 1847652220
Category : Science
Languages : en
Pages : 353
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Book Description
Winner of the 2010 Royal Society Prize for science books Powerful new research methods are providing fresh and vivid insights into the makeup of life. Comparing gene sequences, examining the atomic structure of proteins and looking into the geochemistry of rocks have all helped to explain creation and evolution in more detail than ever before. Nick Lane uses the full extent of this new knowledge to describe the ten greatest inventions of life, based on their historical impact, role in living organisms today and relevance to current controversies. DNA, sex, sight and consciousnesses are just four examples. Lane also explains how these findings have come about, and the extent to which they can be relied upon. The result is a gripping and lucid account of the ingenuity of nature, and a book which is essential reading for anyone who has ever questioned the science behind the glories of everyday life.
Author: Eileen McNamara
Publisher:
ISBN: 9780671796211
Category : Law
Languages : en
Pages : 380
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Book Description
This is the critically-acclaimed true account of the promising young Harvard student's suicide and the bizarre and controversial therapy of his psychiatrist as written by Boston Globe reporter Eileen McNamara. This is a story that has made national headlines.
Author: Patrick J. Buchanan
Publisher: Macmillan
ISBN: 1429990600
Category : Political Science
Languages : en
Pages : 497
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Book Description
The New York Times–bestselling conservative author explains why he believes certain social trends will lead to the downfall of the United States. America is disintegrating. The “one Nation under God, indivisible” of the Pledge of Allegiance is passing away. In a few decades, that America will be gone forever. In its place will arise a country unrecognizable to our parents. This is the thrust of Pat Buchanan’s Suicide of a Superpower, his most controversial and thought-provoking book to date. Buchanan traces the disintegration to three historic changes: America’s loss of her cradle faith, Christianity; the moral, social, and cultural collapse that have followed from that loss; and the slow death of the people who created and ruled the nation. And as our nation disintegrates, our government is failing in its fundamental duties, unable to defend our borders, balance our budgets, or win our wars. How Americans are killing the country they profess to love, and the fate that awaits us if we do not turn around, is what Suicide of a Superpower is all about. Praise for Suicide of a Superpower “Suicide of a Superpower traces the changes in governance and culture in America that foreshadow a decline of epic proportions. . . . Buchanan is no stranger to controversy. Nor is he prone to exaggerate. The crises he describes are real, and he is not afraid to say they ‘may prove too much for our democracy to cope with.’” —Jack Kenny, The New American Magazine “Progressives may recoil at these assertions as well as his positions on immigration, affirmative action and morality, though they may share his sentiments regarding war and America’s unnecessary military presence around the world. Not to disappoint his loyal followers, Buchanan reveals the essence of conservative thought and its origins with clarity and precision.” —Publishers Weekly
Author: Jonah Goldberg
Publisher: Forum Books
ISBN: 1101904941
Category : Political Science
Languages : en
Pages : 482
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Book Description
NEW YORK TIMES BESTSELLER • An urgent argument that America and other democracies are in peril because they have lost the will to defend the values and institutions that sustain freedom and prosperity. “Epic and debate-shifting.”—David Brooks, New York Times Only once in the last 250,000 years have humans stumbled upon a way to lift ourselves out of the endless cycle of poverty, hunger, and war that defines most of history. If democracy, individualism, and the free market were humankind’s destiny, they should have appeared and taken hold a bit earlier in the evolutionary record. The emergence of freedom and prosperity was nothing short of a miracle. As Americans we are doubly blessed, because the radical ideas that made the miracle possible were written not just into the Constitution but in our hearts, laying the groundwork for our uniquely prosperous society. Those ideas are: • Our rights come from God, not from the government. • The government belongs to us; we do not belong to it. • The individual is sovereign. We are all captains of our own souls, not bound by the circumstances of our birth. • The fruits of our labors belong to us. In the last few decades, these political virtues have been turned into vices. As we are increasingly taught to view our traditions as a system of oppression, exploitation, and privilege, the principles of liberty and the rule of law are under attack from left and right. For the West to survive, we must renew our sense of gratitude for what our civilization has given us and rediscover the ideals and habits of the heart that led us out of the bloody muck of the past—or back to the muck we will go.
Author: Richard A. Posner
Publisher: Oxford University Press
ISBN: 0199885362
Category : Law
Languages : en
Pages : 190
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Book Description
Eavesdropping on the phone calls of U.S. citizens; demands by the FBI for records of library borrowings; establishment of military tribunals to try suspected terrorists, including U.S. citizens--many of the measures taken by the Bush administration since 9/11 have sparked heated protests. In Not a Suicide Pact, Judge Richard A. Posner offers a cogent and elegant response to these protests, arguing that personal liberty must be balanced with public safety in the face of grave national danger. Critical of civil libertarians who balk at any curtailment of their rights, even in the face of an unprecedented terrorist threat in an era of proliferation of weapons of mass destruction, Posner takes a fresh look at the most important constitutional issues that have arisen since 9/11. These issues include the constitutional rights of terrorist suspects (whether American citizens or not) to habeas corpus and due process, and their rights against brutal interrogation (including torture) and searches based on less than probable cause. Posner argues that terrorist activity is sui generis--it is neither "war" nor "crime"--and it demands a tailored response, one that gives terror suspects fewer constitutional rights than persons suspected of ordinary criminal activity. Constitutional law must remain fluid, protean, and responsive to the pressure of contemporary events. Posner stresses the limits of law in regulating national security measures and underscores the paradoxical need to recognize a category of government conduct that is at once illegal and morally obligatory. One of America's top legal thinkers, Posner does not pull punches. He offers readers a short, sharp book with a strong point of view that is certain to generate much debate. OXFORD'S NEW INALIENABLE RIGHTS SERIES This is inaugural volume in Oxford's new fourteen-book Inalienable Rights Series. Each book will be a short, analytically sharp exploration of a particular right--to bear arms, to religious freedom, to free speech--clarifying the issues swirling around these rights and challenging us to rethink our most cherished freedoms.
Author: Rachel Heng
Publisher: Henry Holt and Company
ISBN: 1250185351
Category : Fiction
Languages : en
Pages : 352
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Book Description
"A provocative new author. A fascinating debut novel. Read it!” —Jeff VanderMeer In Rachel Heng's debut set in near future New York City—where lives last three hundred years and the pursuit of immortality is all-consuming—Lea must choose between her estranged father and her chance to live forever. Lea Kirino is a “Lifer,” which means that a roll of the genetic dice has given her the potential to live forever—if she does everything right. And Lea is an overachiever. She’s a successful trader on the New York exchange—where instead of stocks, human organs are now bought and sold—she has a beautiful apartment, and a fiancé who rivals her in genetic perfection. And with the right balance of HealthTechTM, rigorous juicing, and low-impact exercise, she might never die. But Lea’s perfect life is turned upside down when she spots her estranged father on a crowded sidewalk. His return marks the beginning of her downfall as she is drawn into his mysterious world of the Suicide Club, a network of powerful individuals and rebels who reject society’s pursuit of immortality, and instead choose to live—and die—on their own terms. In this future world, death is not only taboo; it’s also highly illegal. Soon Lea is forced to choose between a sanitized immortal existence and a short, bittersweet time with a man she has never really known, but who is the only family she has left in the world.
Author: George F. Gilder
Publisher:
ISBN:
Category : Families
Languages : en
Pages : 360
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Book Description
Author: Terri L. Snyder
Publisher: University of Chicago Press
ISBN: 022628056X
Category : History
Languages : en
Pages : 255
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Book Description
Acts of suicide by enslaved people carried significant cultural, legal, and political implications in the emerging slave societies of British America and, later, the United States. This study features a wide range of evidence from ship logs and surgeon's journals, legal and legislative records, newspapers, periodicals, novels, and plays, abolitionist print and slave narratives in order to consider the intimate circumstances, cultural meanings, and political consequences of enslaved peoples' acts of self-destruction in the context of early American slavery.
