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Author: Evelyn Regar
Publisher: CRC Press
ISBN: 9780415383486
Category : Medical
Languages : en
Pages : 776
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Book Description
Given that for centuries, the standard tool to understand diseases in tissues was the microscope and that its major limitation was that only excised tissue could be used, recent technology now permits the examination of diseased tissue in vivo. Optical coherence tomography (OCT) has promising potential when applied to coronary artery disease. OCT has the capability to identify coronary plaque and to distinguish between plaques that are stable and unstable. If the plaques are stable then OCT can direct percutaneous intervention (angioplasty or stenting). Optical coherence tomography is a light-based imaging technology that allows for very high resolution imaging in biological tissues. It has been first applied in ophthalmology, where it soon became the golden standard for the assessment of (epi-) retinal processes. The unique imaging capabilities have raised the interest of researchers and clinicians in the field of cardiovascular disease, since OCT offers unique possibilities to study atherosclerosis pathophysiology in vivo. With over 1.1M Americans having a heart attack this year because of unstable plaque rupture, OCT may have an increasingly important role in the early diagnosis of coronary artery disease. This unique publication offers the reader the basic background to OCT and its role in the diagnosis and management of coronary artery disease. The Handbook of Optical Coherence Tomography in Cardiovascular Research introduces the cardiovascular application of this technology. Clinicians, biologists, engineers and physicist are discussing different aspects of cardiovascular OCT application in a multidisciplinary approach. The handbook offers the readership a concise overview on the current state of the art of vascular OCT imaging and sheds light on a variety of exciting new developments. The physics, technical principles of OCT and its application in a broad spectrum of cardiovascular research areas are summarized by highly recognized specialists. The potential of OCT in peripheral and coronary arteries and in developmental cardiology are described. Each research area is introduced by a clinical expert in the field followed by discussion of different aspects from an engineering, biomedical and clinical perspective. Specifically, the current capabilities for plaque characterization, detection of vulnerable plaque, guidance of interventional procedures, Doppler-assessment, and molecular contrast imaging are being described. The Handbook of Optical Coherence Tomography in Cardiovascular Research targets researchers and clinicians involved in the field of atherosclerosis. The summary of basic physics, engineering solutions, pre-clinical and clinical application covers all relevant aspects and will be a valuable reference source.
Author: Evelyn Regar
Publisher: CRC Press
ISBN: 9780415383486
Category : Medical
Languages : en
Pages : 776
Get Book Here
Book Description
Given that for centuries, the standard tool to understand diseases in tissues was the microscope and that its major limitation was that only excised tissue could be used, recent technology now permits the examination of diseased tissue in vivo. Optical coherence tomography (OCT) has promising potential when applied to coronary artery disease. OCT has the capability to identify coronary plaque and to distinguish between plaques that are stable and unstable. If the plaques are stable then OCT can direct percutaneous intervention (angioplasty or stenting). Optical coherence tomography is a light-based imaging technology that allows for very high resolution imaging in biological tissues. It has been first applied in ophthalmology, where it soon became the golden standard for the assessment of (epi-) retinal processes. The unique imaging capabilities have raised the interest of researchers and clinicians in the field of cardiovascular disease, since OCT offers unique possibilities to study atherosclerosis pathophysiology in vivo. With over 1.1M Americans having a heart attack this year because of unstable plaque rupture, OCT may have an increasingly important role in the early diagnosis of coronary artery disease. This unique publication offers the reader the basic background to OCT and its role in the diagnosis and management of coronary artery disease. The Handbook of Optical Coherence Tomography in Cardiovascular Research introduces the cardiovascular application of this technology. Clinicians, biologists, engineers and physicist are discussing different aspects of cardiovascular OCT application in a multidisciplinary approach. The handbook offers the readership a concise overview on the current state of the art of vascular OCT imaging and sheds light on a variety of exciting new developments. The physics, technical principles of OCT and its application in a broad spectrum of cardiovascular research areas are summarized by highly recognized specialists. The potential of OCT in peripheral and coronary arteries and in developmental cardiology are described. Each research area is introduced by a clinical expert in the field followed by discussion of different aspects from an engineering, biomedical and clinical perspective. Specifically, the current capabilities for plaque characterization, detection of vulnerable plaque, guidance of interventional procedures, Doppler-assessment, and molecular contrast imaging are being described. The Handbook of Optical Coherence Tomography in Cardiovascular Research targets researchers and clinicians involved in the field of atherosclerosis. The summary of basic physics, engineering solutions, pre-clinical and clinical application covers all relevant aspects and will be a valuable reference source.
Author: Bruno Andreotti
Publisher: Cambridge University Press
ISBN: 1107245117
Category : Science
Languages : en
Pages : 471
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Book Description
Sand, rice, sugar, snow, cement... Although ubiquitous in our daily lives, granular media still challenge engineers and fascinate researchers. This book provides the state-of-the-art of the physics of granular media and recent advances in the field. The book presents the fundamental properties of granular materials: interactions between grains; solid, liquid and gaseous behaviours; coupling with a fluid; and sediment transport and formation of geological structures. Descriptions of the phenomena combine qualitative and formal arguments, coming from areas as diverse as elasticity, plasticity, statistical physics, fluid mechanics and geomorphology. Many examples of the astonishing behaviours of granular media are presented, including avalanches, segregation, dune song and quicksand. This book is ideal for graduate students and researchers in physics, applied mathematics and engineering.
Author: António S. Cardoso
Publisher: CRC Press
ISBN: 1351003615
Category : Technology & Engineering
Languages : en
Pages : 1656
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Book Description
Numerical Methods in Geotechnical Engineering IX contains 204 technical and scientific papers presented at the 9th European Conference on Numerical Methods in Geotechnical Engineering (NUMGE2018, Porto, Portugal, 25—27 June 2018). The papers cover a wide range of topics in the field of computational geotechnics, providing an overview of recent developments on scientific achievements, innovations and engineering applications related to or employing numerical methods. They deal with subjects from emerging research to engineering practice, and are grouped under the following themes: Constitutive modelling and numerical implementation Finite element, discrete element and other numerical methods. Coupling of diverse methods Reliability and probability analysis Large deformation – large strain analysis Artificial intelligence and neural networks Ground flow, thermal and coupled analysis Earthquake engineering, soil dynamics and soil-structure interactions Rock mechanics Application of numerical methods in the context of the Eurocodes Shallow and deep foundations Slopes and cuts Supported excavations and retaining walls Embankments and dams Tunnels and caverns (and pipelines) Ground improvement and reinforcement Offshore geotechnical engineering Propagation of vibrations Following the objectives of previous eight thematic conferences, (1986 Stuttgart, Germany; 1990 Santander, Spain; 1994 Manchester, United Kingdom; 1998 Udine, Italy; 2002 Paris, France; 2006 Graz, Austria; 2010 Trondheim, Norway; 2014 Delft, The Netherlands), Numerical Methods in Geotechnical Engineering IX updates the state-of-the-art regarding the application of numerical methods in geotechnics, both in a scientific perspective and in what concerns its application for solving practical boundary value problems. The book will be much of interest to engineers, academics and professionals involved or interested in Geotechnical Engineering.
Author: Manuel de Matos Fernandes
Publisher: CRC Press
ISBN: 0429823193
Category : Technology & Engineering
Languages : en
Pages : 935
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Book Description
NUMGE 2018 is the ninth in a series of conferences on Numerical Methods in Geotechnical Engineering organized by the ERTC7 under the auspices of the International Society for Soil Mechanics and Geotechnical Engineering (ISSMGE). The first conference was held in 1986 in Stuttgart, Germany and the series continued every four years (1990 Santander, Spain; 1994 Manchester, United Kingdom; 1998 Udine, Italy; 2002 Paris, France; 2006 Graz, Austria; 2010 Trondheim, Norway; 2014 Delft, The Netherlands). The conference provides a forum for exchange of ideas and discussion on topics related to numerical modelling in geotechnical engineering. Both senior and young researchers, as well as scientists and engineers from Europe and overseas, are invited to attend this conference to share and exchange their knowledge and experiences. This work is the first volume of NUMGE 2018.
Author: Masayuki Hyodo
Publisher: CRC Press
ISBN: 1351377094
Category : Science
Languages : en
Pages : 550
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Book Description
Microscopic re-examination of geomaterials consisting of aggregates can shed light on macroscopic behaviour, including compressibility, anisotropy, yielding, creep, cyclic liquefaction and shear rupture. As a result of this process of examination, new methods of material characterization emerge, leading to a greater degree of accuracy in the specification of new constitutive models with physically-meaningful parameters. The impetus behind this development is an increasing awareness on sustainability, leading to the more efficient use of recycled materials for geotechnical applications. The characteristics of recycled materials, such as compressibility and self-hardening, may differ significantly from those of natural materials, and it is crucial that evaluation is made from a specifically particulate perspective.
Author: Jacek Tejchman
Publisher: Springer Science & Business Media
ISBN: 3319003186
Category : Science
Languages : en
Pages : 503
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Book Description
During confined flow of bulk solids in silos some characteristic phenomena can be created, such as: sudden and significant increase of wall stresses, different flow patterns, formation and propagation of wall and interior shear zones, fluctuation of pressures and, strong autogenous dynamic effects. These phenomena have not been described or explained in detail yet. The main intention of the experimental and theoretical research presented in this book is to explain the above mentioned phenomena in granular bulk solids and to describe them with numerical FE models verified by experimental results.
Author: Andreas Schadschneider
Publisher: Springer Science & Business Media
ISBN: 3540476415
Category : Mathematics
Languages : en
Pages : 719
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Book Description
This book again continues the biannual series of (now six) conference proceedings, which has become a classical reference in traffic and granular research alike. It addresses new developments at the borderline between physics, engineering and computational science. Complex systems, where many simple agents, be it vehicles or particles, give rise to surprising and fascinating phenomena.
Author: Qiang Yang
Publisher: Springer Science & Business Media
ISBN: 3642328148
Category : Science
Languages : en
Pages : 779
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Book Description
The Second International Symposium on Constitutive Modeling of Geomaterials: Advances and New Applications (IS-Model 2012), is to be held in Beijing, China, during October 15-16, 2012. The symposium is organized by Tsinghua University, the International Association for Computer Methods and Advances in Geomechanics (IACMAG), the Committee of Numerical and Physical Modeling of Rock Mass, Chinese Society for Rock Mechanics and Engineering, and the Committee of Constitutive Relations and Strength Theory, China Institution of Soil Mechanics and Geotechnical Engineering, China Civil Engineering Society. This Symposium follows the first successful International Workshop on Constitutive Modeling held in Hong Kong, which was organized by Prof. JH Yin in 2007. Constitutive modeling of geomaterials has been an active research area for a long period of time. Different approaches have been used in the development of various constitutive models. A number of models have been implemented in the numerical analyses of geotechnical structures. The objective of the symposium is to provide a forum for researchers and engineers working or interested in the area of constitutive modeling to meet together and share new ideas, achievements and experiences through presentations and discussions. Emphasis is placed on recent advances of constitutive modeling and its applications in both theoretic and experimental aspects. Six famous scholars have been invited for the plenary speeches of the symposiums. Some prominent scholars have been invited to organize four specialized workshops on hot topics, including “Time-dependent stress-strain behavior of geomaterials”, “Constitutive modeling within critical state soil mechanics”, “Multiscale and multiphysics in geomaterials”, and “Damage to failure in rock structures”. A total of 49 papers are included in the above topics. In addition, 51 papers are grouped under three topics covering “Behaviour of geomaterials”, “Constitutive model”, and “Applications”. The editors expect that the book can be helpful as a reference to all those in the field of constitutive modeling of geomaterials.
Author: Bernard Cambou
Publisher: John Wiley & Sons
ISBN: 1118623088
Category : Science
Languages : en
Pages : 263
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Book Description
Nearly all solids are compised of grains. However most studies treat materials as a continious solid. The book applies analysis used on loose granular materials to dense grainular materials. This title’s main focus is devoted to static or dynamic loadings applied to dense materials, although rapid flows and widely dispersed media are also mentioned briefly. Three essential areas are covered: Local variable analysis: Contact forces, displacements and rotations, orientation of contacting particles and fabric tensors are all examples of local variables. Their statistical distributions, such as spatial distribution and possible localization, are analyzed, taking into account experimental results or numerical simulations. Change of scales procedures: Also known as “homogenization techniques”, these procedures make it possible to construct continuum laws to be used in a continuum mechanics approach or performing smaller scale analyses. Numerical modeling: Several methods designed to calculate approximate solutions of dynamical equations together with unilateral contact and frictional laws are presented, including molecular dynamics, the distinct element method and non-smooth contact dynamics. Numerical examples are given and the quality of numerical approximations is discussed.
Author: Malte Henkel
Publisher: Springer Science & Business Media
ISBN: 3540696830
Category : Science
Languages : en
Pages : 362
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Book Description
Understanding cooperative phenomena far from equilibrium is one of the fascinating challenges of present-day many-body physics. Glassy behaviour and the physical ageing process of such materials are paradigmatic examples. The present volume, primarily intended as introduction and reference, collects six extensive lectures addressing selected experimental and theoretical issues in the field of glassy systems.
