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Author: Changyou Gao
Publisher: Springer
ISBN: 9811022933
Category : Medical
Languages : en
Pages : 381
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Book Description
This book reviews state-of-the-art of polymeric biomaterials for regenerative medicine, and highlights advances in both basic science and clinical practice. It summarizes the latest techniques in polymeric scaffold fabrication, delivery carriers, physicochemical property modulation, as well as their influence on adhesion and the performance of biomolecules, cells and tissues. It also describes methods for creating biofunctional surfaces/interfaces and subsequently modulating the host response to implantable materials. Lastly, it discusses the applications of biomaterials and constructs in soft-tissue regenerative medicine. It is a valuable resource for materials scientists and engineers wishing to identify research priorities to fulfill clinical needs and provides physicians with insights into emerging novel biomaterials. This integrated approach also offers engineering students a sense of the relevance of materials science in the development of novel therapeutic strategies.
Author: Changyou Gao
Publisher: Springer
ISBN: 9811022933
Category : Medical
Languages : en
Pages : 381
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Book Description
This book reviews state-of-the-art of polymeric biomaterials for regenerative medicine, and highlights advances in both basic science and clinical practice. It summarizes the latest techniques in polymeric scaffold fabrication, delivery carriers, physicochemical property modulation, as well as their influence on adhesion and the performance of biomolecules, cells and tissues. It also describes methods for creating biofunctional surfaces/interfaces and subsequently modulating the host response to implantable materials. Lastly, it discusses the applications of biomaterials and constructs in soft-tissue regenerative medicine. It is a valuable resource for materials scientists and engineers wishing to identify research priorities to fulfill clinical needs and provides physicians with insights into emerging novel biomaterials. This integrated approach also offers engineering students a sense of the relevance of materials science in the development of novel therapeutic strategies.
Author: Rui L. Reis
Publisher: Springer Science & Business Media
ISBN: 940100305X
Category : Science
Languages : en
Pages : 419
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Book Description
Biodegradable, polymer-based systems are playing an increasingly pivotal role in tissue engineering replacement and regeneration. This type of biology-driven materials science is slated to be one of the key research areas of the 21st century. The following aspects are crucial: the development of adequate human cell culture to produce the tissues in adequate polymer scaffold materials; the development of culture technology with which human tissues can be grown ex-vivo in 3D polymer matrices; the development of material technology for producing the degradable, 3D matrices, having mechanical properties similar to natural tissue. In addressing these and similar problems, the book contains chapters on biodegradable polymers, polymeric biomaterials, surface modification for controlling cell-material interactions, scaffold design and processing, biomimetic coatings, biocompatibility evaluation, tissue engineering constructs, cell isolation, characterisation and culture, and controlled release of bioactive agents.
Author: Sangamesh G. Kum bar
Publisher: Newnes
ISBN: 0123972906
Category : Technology & Engineering
Languages : en
Pages : 421
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Book Description
Polymers are important and attractive biomaterials for researchers and clinical applications due to the ease of tailoring their chemical, physical and biological properties for target devices. Due to this versatility they are rapidly replacing other classes of biomaterials such as ceramics or metals. As a result, the demand for biomedical polymers has grown exponentially and supports a diverse and highly monetized research community. Currently worth $1.2bn in 2009 (up from $650m in 2000), biomedical polymers are expected to achieve a CAGR of 9.8% until 2015, supporting a current research community of approximately 28,000+. Summarizing the main advances in biopolymer development of the last decades, this work systematically covers both the physical science and biomedical engineering of the multidisciplinary field. Coverage extends across synthesis, characterization, design consideration and biomedical applications. The work supports scientists researching the formulation of novel polymers with desirable physical, chemical, biological, biomechanical and degradation properties for specific targeted biomedical applications. - Combines chemistry, biology and engineering for expert and appropriate integration of design and engineering of polymeric biomaterials - Physical, chemical, biological, biomechanical and degradation properties alongside currently deployed clinical applications of specific biomaterials aids use as single source reference on field. - 15+ case studies provides in-depth analysis of currently used polymeric biomaterials, aiding design considerations for the future
Author: Rajesh K. Kesharwani
Publisher: CRC Press
ISBN: 1000400956
Category : Medical
Languages : en
Pages : 352
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Book Description
This new volume on applications and advances in tissue engineering presents significant, state-of-the-art developments in this exciting area of research. It highlights some of the most important applied research on the applications of tissue engineering along with its different components, specifically different types of biomaterials. It looks at the various issues involved in tissue engineering, including smart polymeric biomaterials, gene therapy, tissue engineering in reconstruction and regeneration of visceral organs, skin tissue engineering, bone and muscle regeneration, and applications in tropical medicines. Covering a wide range of issues in tissue engineering, the volume Provides an overview of the efficacy of the different biomaterials employed in tissue engineering (such as skin regeneration, nerve regeneration, artificial blood vessels, bone regeneration). Looks at smart polymeric biomaterials in tissue engineering Discusses the hybrid approach of tissue engineering in conjunction with gene therapy Explores using tissue engineering in the management of tropical diseases Considers various skin tissue engineering applications, including wound healing methods, skin substitutes and other materials Reports on the use of various biomaterials in bone and muscle regeneration Describes the use of tissue engineering in reconstruction and regeneration of visceral organs Covers polysaccharides and proteins-based hydrogels for tissue engineering applications Providing an abundance of advanced research and information, Tissue Engineering: Applications and Advancements will be a valuable resource for medical researchers, pharmaceutical manufacturers, healthcare personnel, and academicians.
Author: Aldo R. Boccaccini
Publisher: Elsevier
ISBN: 1845693817
Category : Technology & Engineering
Languages : en
Pages : 625
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Book Description
Technology and research in the field of tissue engineering has drastically increased within the last few years to the extent that almost every tissue and organ of the human body could potentially be regenerated. With its distinguished editors and international team of contributors, Tissue Engineering using Ceramics and Polymers reviews the latest research and advances in this thriving area and how they can be used to develop treatments for disease states. Part one discusses general issues such as ceramic and polymeric biomaterials, scaffolds, transplantation of engineered cells, surface modification and drug delivery. Later chapters review characterisation using x-ray photoelectron spectroscopy and secondary ion mass spectrometry as well as environmental scanning electron microscopy and Raman micro-spectroscopy. Chapters in part two analyse bone regeneration and specific types of tissue engineering and repair such as cardiac, intervertebral disc, skin, kidney and bladder tissue. The book concludes with the coverage of themes such as nerve bioengineering and the micromechanics of hydroxyapatite-based biomaterials and tissue scaffolds. Tissue Engineering using Ceramics and Polymers is an innovative reference for professionals and academics involved in the field of tissue engineering. - An innovative and up-to-date reference for professionals and academics - Environmental scanning electron microscopy is discussed - Analyses bone regeneration and specific types of tisue engineering
Author: Maria Cristina Tanzi
Publisher: Woodhead Publishing
ISBN: 0081007434
Category : Technology & Engineering
Languages : en
Pages : 503
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Book Description
Characterization of Polymeric Biomaterials presents a comprehensive introduction on the topic before discussing the morphology and surface characterization of biomedical polymers. The structural, mechanical, and biological characterization is described in detail, followed by invaluable case studies of polymer biomaterial implants. With comprehensive coverage of both theoretical and experimental information, this title will provide scientists with an essential guide on the topic of these materials which are regularly used for clinical applications, such as implants and drug delivery devices. However, a range of novel polymers and the development and modification of existing medical polymers means that there is an ongoing need to satisfy particular design requirements. This book explains the critical and fundamentals methods to characterize polymer materials for biomedical applications. - Presents a self-contained reference on the characterization of polymeric biomaterials - Provides comprehensive information on how to characterize biomedical polymers in order to improve design and synthesis - Includes useful case studies that demonstrate the characterization of biomaterial implants
Author: Sang Jin Lee
Publisher: Academic Press
ISBN: 012802500X
Category : Medical
Languages : en
Pages : 460
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Book Description
In Situ Tissue Regeneration: Host Cell Recruitment and Biomaterial Design explores the body's ability to mobilize endogenous stem cells to the site of injury and details the latest strategies developed for inducing and supporting the body's own regenerating capacity. From the perspective of regenerative medicine and tissue engineering, this book describes the mechanism of host cell recruitment, cell sourcing, cellular and molecular roles in cell differentiation, navigational cues and niche signals, and a tissue-specific smart biomaterial system that can be applied to a wide range of therapies. The work is divided into four sections to provide a thorough overview and helpful hints for future discoveries: endogenous cell sources; biochemical and physical cues; smart biomaterial development; and applications. - Explores the body's ability to mobilize endogenous stem cells to the site of injury - Details the latest strategies developed for inducing and supporting the body's own regenerating capacity - Presents smart biomaterials in cell-based tissue engineering applications—from the cell level to applications—in the first unified volume - Features chapter authors and editors who are authorities in this emerging field - Prioritizes a discussion of the future direction of smart biomaterials for in situ tissue regeneration, which will affect an emerging and lucrative industry
Author: Severian Dumitriu
Publisher: CRC Press
ISBN: 142009470X
Category : Medical
Languages : en
Pages : 922
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Book Description
The third edition of a bestseller, this comprehensive reference presents the latest polymer developments and most up-to-date applications of polymeric biomaterials in medicine. Expanded into two volumes, the first volume covers the structure and properties of synthetic and natural polymers as well as bioresorbable hybrid membranes, drug delivery systems, cell bioassay systems, and electrospinning for regenerative medicine. This substantially larger resource includes state-of-the-art research and successful breakthroughs in applications that have occurred in the last ten years.
Author: Severian Dumitriu
Publisher: CRC Press
ISBN: 1420094696
Category : Science
Languages : en
Pages : 840
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Book Description
Biomaterials have had a major impact on the practice of contemporary medicine and patient care. Growing into a major interdisciplinary effort involving chemists, biologists, engineers, and physicians, biomaterials development has enabled the creation of high-quality devices, implants, and drug carriers with greater biocompatibility and biofunctiona
Author: Aldo R. Boccaccini
Publisher: Elsevier
ISBN: 0857097164
Category : Science
Languages : en
Pages : 743
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Book Description
The second edition of Tissue Engineering Using Ceramics and Polymers comprehensively reviews the latest advances in this area rapidly evolving area of biomaterials science. Part one considers the biomaterials used for tissue engineering. It introduces the properties and processing of bioactive ceramics and glasses, as well as polymeric biomaterials, particularly biodegradable polymer phase nanocomposites. Part two reviews the advances in techniques for processing, characterization, and modeling of materials. The topics covered range from nanoscale design in biomineralization strategies for bone tissue engineering to microscopy techniques for characterizing cells to materials for perfusion bioreactors. Further, carrier systems and biosensors in biomedical applications are considered. Finally, part three looks at the specific types of tissue and organ regeneration, with chapters concerning kidney, bladder, peripheral nerve, small intestine, skeletal muscle, cartilage, liver, and myocardial tissue engineering. Important developments in collagen-based tubular constructs, bioceramic nanoparticles, and multifunctional scaffolds for tissue engineering and drug delivery are also explained. Tissue Engineering Using Ceramics and Polymers is a valuable reference tool for both academic researchers and scientists involved in biomaterials or tissue engineering, including the areas of bone and soft-tissue reconstruction and repair, and organ regeneration. - Second edition comprehensively examines the latest advances in ceramic and polymers in tissue engineering - Provides readers with general information on polymers and ceramics and looks at the processing, characterization, and modeling - Reviews the latest research and advances in tissue and organ regeneration using ceramics and polymers
