Author: J. Milton Harris
Publisher: Springer Science & Business Media
ISBN: 1489907033
Category : Medical
Languages : en
Pages : 395
Book Description
The idea for this book came from discussions among participants in a symposium on biotechnical applications at the "Pacifichem 89" meeting in Honolulu. It was the majority opinion of this group that a volume dedicated to biotechnical and biomedical applications of PEG chemistry would enhance research and development in this area. Though the book was conceived at the Honolulu meeting, it is not a proceedings of this symposium. Several groups who did not participate in this meeting are repre sented in the book, and the book incorporates much work done after the meeting. The book does not include contributions in all related areas to which PEG chemistry has been applied. Several invited researchers declined to parti.:ipate, and there is not enough space in this single volume to properly cover all submissions. Chapter I-an overview of the topic-discusses in brief applications not given detailed coverage in specifically devoted chapters. The following topics are covered: introduction to and fundamental properties of PEG and derivatives in Chapters 1-3; separations using aqueous polymer two-phase partitioning in Chapters 4-6; PEG-proteins as catalysts in biotechnical applications in Chapters 7 and 8; biomedical applications of PEG-proteins in Chapters 9-13; PEG modified surfaces for a variety of biomedical and biotechnical applications in Chapters 14-20; and synthesis of new PEG derivatives in Chapters 21 and 22.
Poly(Ethylene Glycol) Chemistry
Author: J. Milton Harris
Publisher: Springer Science & Business Media
ISBN: 1489907033
Category : Medical
Languages : en
Pages : 395
Book Description
The idea for this book came from discussions among participants in a symposium on biotechnical applications at the "Pacifichem 89" meeting in Honolulu. It was the majority opinion of this group that a volume dedicated to biotechnical and biomedical applications of PEG chemistry would enhance research and development in this area. Though the book was conceived at the Honolulu meeting, it is not a proceedings of this symposium. Several groups who did not participate in this meeting are repre sented in the book, and the book incorporates much work done after the meeting. The book does not include contributions in all related areas to which PEG chemistry has been applied. Several invited researchers declined to parti.:ipate, and there is not enough space in this single volume to properly cover all submissions. Chapter I-an overview of the topic-discusses in brief applications not given detailed coverage in specifically devoted chapters. The following topics are covered: introduction to and fundamental properties of PEG and derivatives in Chapters 1-3; separations using aqueous polymer two-phase partitioning in Chapters 4-6; PEG-proteins as catalysts in biotechnical applications in Chapters 7 and 8; biomedical applications of PEG-proteins in Chapters 9-13; PEG modified surfaces for a variety of biomedical and biotechnical applications in Chapters 14-20; and synthesis of new PEG derivatives in Chapters 21 and 22.
Publisher: Springer Science & Business Media
ISBN: 1489907033
Category : Medical
Languages : en
Pages : 395
Book Description
The idea for this book came from discussions among participants in a symposium on biotechnical applications at the "Pacifichem 89" meeting in Honolulu. It was the majority opinion of this group that a volume dedicated to biotechnical and biomedical applications of PEG chemistry would enhance research and development in this area. Though the book was conceived at the Honolulu meeting, it is not a proceedings of this symposium. Several groups who did not participate in this meeting are repre sented in the book, and the book incorporates much work done after the meeting. The book does not include contributions in all related areas to which PEG chemistry has been applied. Several invited researchers declined to parti.:ipate, and there is not enough space in this single volume to properly cover all submissions. Chapter I-an overview of the topic-discusses in brief applications not given detailed coverage in specifically devoted chapters. The following topics are covered: introduction to and fundamental properties of PEG and derivatives in Chapters 1-3; separations using aqueous polymer two-phase partitioning in Chapters 4-6; PEG-proteins as catalysts in biotechnical applications in Chapters 7 and 8; biomedical applications of PEG-proteins in Chapters 9-13; PEG modified surfaces for a variety of biomedical and biotechnical applications in Chapters 14-20; and synthesis of new PEG derivatives in Chapters 21 and 22.
PEGylated Protein Drugs: Basic Science and Clinical Applications
Author: Francesco M. Veronese
Publisher: Springer Science & Business Media
ISBN: 3764386797
Category : Medical
Languages : en
Pages : 289
Book Description
PEGylation technology and key applications are introduced by this topical volume. Basic physical and chemical properties of PEG as basis for altering/improving in vivo behaviour of PEG-conjugates such as increased stability, improved PK/PD, and decreased immunogenicity, are discussed. Furthermore, chemical and enzymatic strategies for the coupling and the conjugate characterization are reported. Following chapters describe approved and marketed PEG-proteins and PEG-oligonucleotides as well as conjugates in various stages of clinical development.
Publisher: Springer Science & Business Media
ISBN: 3764386797
Category : Medical
Languages : en
Pages : 289
Book Description
PEGylation technology and key applications are introduced by this topical volume. Basic physical and chemical properties of PEG as basis for altering/improving in vivo behaviour of PEG-conjugates such as increased stability, improved PK/PD, and decreased immunogenicity, are discussed. Furthermore, chemical and enzymatic strategies for the coupling and the conjugate characterization are reported. Following chapters describe approved and marketed PEG-proteins and PEG-oligonucleotides as well as conjugates in various stages of clinical development.
Public Health Consequences of E-Cigarettes
Author: National Academies of Sciences, Engineering, and Medicine
Publisher: National Academies Press
ISBN: 030946837X
Category : Medical
Languages : en
Pages : 775
Book Description
Millions of Americans use e-cigarettes. Despite their popularity, little is known about their health effects. Some suggest that e-cigarettes likely confer lower risk compared to combustible tobacco cigarettes, because they do not expose users to toxicants produced through combustion. Proponents of e-cigarette use also tout the potential benefits of e-cigarettes as devices that could help combustible tobacco cigarette smokers to quit and thereby reduce tobacco-related health risks. Others are concerned about the exposure to potentially toxic substances contained in e-cigarette emissions, especially in individuals who have never used tobacco products such as youth and young adults. Given their relatively recent introduction, there has been little time for a scientific body of evidence to develop on the health effects of e-cigarettes. Public Health Consequences of E-Cigarettes reviews and critically assesses the state of the emerging evidence about e-cigarettes and health. This report makes recommendations for the improvement of this research and highlights gaps that are a priority for future research.
Publisher: National Academies Press
ISBN: 030946837X
Category : Medical
Languages : en
Pages : 775
Book Description
Millions of Americans use e-cigarettes. Despite their popularity, little is known about their health effects. Some suggest that e-cigarettes likely confer lower risk compared to combustible tobacco cigarettes, because they do not expose users to toxicants produced through combustion. Proponents of e-cigarette use also tout the potential benefits of e-cigarettes as devices that could help combustible tobacco cigarette smokers to quit and thereby reduce tobacco-related health risks. Others are concerned about the exposure to potentially toxic substances contained in e-cigarette emissions, especially in individuals who have never used tobacco products such as youth and young adults. Given their relatively recent introduction, there has been little time for a scientific body of evidence to develop on the health effects of e-cigarettes. Public Health Consequences of E-Cigarettes reviews and critically assesses the state of the emerging evidence about e-cigarettes and health. This report makes recommendations for the improvement of this research and highlights gaps that are a priority for future research.
Polyethylene Glycol as an Embedment for Microscopy and Histochemistry
Author: Johnson K. Gao
Publisher: CRC Press
ISBN: 9780849343230
Category : Science
Languages : en
Pages : 140
Book Description
Polyethylene Glycol as an Embedment for Microscopy and Histochemistry is the first book devoted to discussing polyethylene glycol (PEG) as a biological sample embedment for microscopy (EM and LM). Its contributors are international authorities in all areas of investigation using PEG as an embedding medium. The book provides broad coverage of a variety of methods, including low molecular PEG-cryosection, agarose block section-transferring technique, PEG section for scanning electron microscopy, nucleic acid in situ hybridization study, monoclonal antibody screening, PEG-celloidin mixture embedding method, and diethylene glycol distearate used as removable embedment. This practical volume will interest histologists, histochemists, cytochemists, cell biologists, and other researchers using PEG in microscopy.
Publisher: CRC Press
ISBN: 9780849343230
Category : Science
Languages : en
Pages : 140
Book Description
Polyethylene Glycol as an Embedment for Microscopy and Histochemistry is the first book devoted to discussing polyethylene glycol (PEG) as a biological sample embedment for microscopy (EM and LM). Its contributors are international authorities in all areas of investigation using PEG as an embedding medium. The book provides broad coverage of a variety of methods, including low molecular PEG-cryosection, agarose block section-transferring technique, PEG section for scanning electron microscopy, nucleic acid in situ hybridization study, monoclonal antibody screening, PEG-celloidin mixture embedding method, and diethylene glycol distearate used as removable embedment. This practical volume will interest histologists, histochemists, cytochemists, cell biologists, and other researchers using PEG in microscopy.
Capture and Utilization of Carbon Dioxide with Polyethylene Glycol
Author: Zhen-Zhen Yang
Publisher: Springer Science & Business Media
ISBN: 3642312683
Category : Science
Languages : en
Pages : 88
Book Description
In this volume, Professor He and his coworkers summarize polyethylene glycol (PEG)-promoted CO2 chemistry on the basis of understanding about phase behavior of PEG/CO2 system and reaction mechanism at molecular level. As PEG could be utilized as a green replacement for organic solvents, phase-transfer catalyst, surfactant, support in various reaction systems, significantly promoting catalytic activity and recovering expensive metal catalysts, particularly regarded as a CO2-philic material, the authors focus on special applications of PEG in CO2 capture and utilization, including PEG-functionalized catalysts for efficient transformation of CO2 and PEG-functionalized absorbents for efficient CO2 capture. Furthermore, they describe carbon capture and utilization strategy as an alternative approach to address the energy penalty problem in carbon capture and storage. Interestingly, the authors also discuss PEG radical chemistry in dense CO2 as rather creative and unusual use of PEG, presumably serves as a reaction medium and a radical initiator for radical chemistry.
Publisher: Springer Science & Business Media
ISBN: 3642312683
Category : Science
Languages : en
Pages : 88
Book Description
In this volume, Professor He and his coworkers summarize polyethylene glycol (PEG)-promoted CO2 chemistry on the basis of understanding about phase behavior of PEG/CO2 system and reaction mechanism at molecular level. As PEG could be utilized as a green replacement for organic solvents, phase-transfer catalyst, surfactant, support in various reaction systems, significantly promoting catalytic activity and recovering expensive metal catalysts, particularly regarded as a CO2-philic material, the authors focus on special applications of PEG in CO2 capture and utilization, including PEG-functionalized catalysts for efficient transformation of CO2 and PEG-functionalized absorbents for efficient CO2 capture. Furthermore, they describe carbon capture and utilization strategy as an alternative approach to address the energy penalty problem in carbon capture and storage. Interestingly, the authors also discuss PEG radical chemistry in dense CO2 as rather creative and unusual use of PEG, presumably serves as a reaction medium and a radical initiator for radical chemistry.
Poly(ethylene Glycol)
Author: J. Milton Harris
Publisher:
ISBN:
Category : Science
Languages : en
Pages : 512
Book Description
This volume provides an interdisciplinary analysis of current biological applications of poly(ethylene glycol) (PEG). It includes a wide array of topics useful to materials scientists, organic chemists, biochemists, and bioengineers interested in drug delivery systems, pharmaceuticals and other biomaterials. The applications discussed include PEG-modified proteins, liposomes, drugs, surfaces of materials, and hydrogels. The volume also includes a review of PEG-oligonucleotides and a concise summary of the toxicology of PEG and its derivatives.
Publisher:
ISBN:
Category : Science
Languages : en
Pages : 512
Book Description
This volume provides an interdisciplinary analysis of current biological applications of poly(ethylene glycol) (PEG). It includes a wide array of topics useful to materials scientists, organic chemists, biochemists, and bioengineers interested in drug delivery systems, pharmaceuticals and other biomaterials. The applications discussed include PEG-modified proteins, liposomes, drugs, surfaces of materials, and hydrogels. The volume also includes a review of PEG-oligonucleotides and a concise summary of the toxicology of PEG and its derivatives.
Technical Report for Ethylene Glycol/propylene Glycol
Author:
Publisher:
ISBN:
Category : Ethers
Languages : en
Pages : 132
Book Description
Publisher:
ISBN:
Category : Ethers
Languages : en
Pages : 132
Book Description
Toxic Substances
Author: National Institute for Occupational Safety and Health
Publisher:
ISBN:
Category : Hazardous substances
Languages : en
Pages : 1004
Book Description
Publisher:
ISBN:
Category : Hazardous substances
Languages : en
Pages : 1004
Book Description
Toxicological Profile for Ethylene Glycol and Propylene Glycol
Author:
Publisher:
ISBN:
Category : Ethers
Languages : en
Pages : 290
Book Description
Publisher:
ISBN:
Category : Ethers
Languages : en
Pages : 290
Book Description
Draft Toxicological Profile for Ethylene Glycol
Author:
Publisher:
ISBN:
Category : Ethylene glycol
Languages : en
Pages : 320
Book Description
Publisher:
ISBN:
Category : Ethylene glycol
Languages : en
Pages : 320
Book Description