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Author: Elizabeth E. Hood
Publisher: Springer Science & Business Media
ISBN: 9401726930
Category : Medical
Languages : en
Pages : 232
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Book Description
This exciting volume Plants as Factories for Protein Production, edited by Drs. Elizabeth E. Hood and John A. Howard, contains chapters by experts in the field of molecular farming. The information within addresses the leading plant systems for recombinant protein production, as well as the progress being made in leading product categories - human pharmaceuticals, animal health, and industrial enzymes. More importantly, the book includes chapters that address the hot topics of production, containment, regulatory, and legal aspects that are quickly coming to the forefront of the industry. This most timely text is appropriate for graduate students and post-doctoral fellows, as well as being a key text for faculty, pharmaceutical producers, and industrial enzyme users.
Author: Elizabeth E. Hood
Publisher: Springer Science & Business Media
ISBN: 9401726930
Category : Medical
Languages : en
Pages : 232
Get Book Here
Book Description
This exciting volume Plants as Factories for Protein Production, edited by Drs. Elizabeth E. Hood and John A. Howard, contains chapters by experts in the field of molecular farming. The information within addresses the leading plant systems for recombinant protein production, as well as the progress being made in leading product categories - human pharmaceuticals, animal health, and industrial enzymes. More importantly, the book includes chapters that address the hot topics of production, containment, regulatory, and legal aspects that are quickly coming to the forefront of the industry. This most timely text is appropriate for graduate students and post-doctoral fellows, as well as being a key text for faculty, pharmaceutical producers, and industrial enzyme users.
Author: Allison R. Kermode
Publisher: John Wiley & Sons
ISBN: 1118801482
Category : Science
Languages : en
Pages : 496
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Book Description
A single volume collection that surveys the exciting field of plant-made pharmaceuticals and industrial proteins This comprehensive book communicates the recent advances and exciting potential for the expanding area of plant biotechnology and is divided into six sections. The first three sections look at the current status of the field, and advances in plant platforms and strategies for improving yields, downstream processing, and controlling post-translational modifications of plant-made recombinant proteins. Section four reviews high-value industrial and pharmacological proteins that are successfully being produced in established and emerging plant platforms. The fifth section looks at regulatory challenges facing the expansion of the field. The final section turns its focus toward small molecule therapeutics, drug screening, plant specialized metabolites, and plants as model organisms to study human disease processes. Molecular Pharming: Applications, Challenges and Emerging Areas offers in-depth coverage of molecular biology of plant expression systems and manipulation of glycosylation processes in plants; plant platforms, subcellular targeting, recovery, and downstream processing; plant-derived protein pharmaceuticals and case studies; regulatory issues; and emerging areas. It is a valuable resource for researchers that are in the field of plant molecular pharming, as well as for those conducting basic research in gene expression, protein quality control, and other subjects relevant to molecular and cellular biology. Broad ranging coverage of a key area of plant biotechnology Describes efforts to produce pharmaceutical and industrial proteins in plants Provides reviews of recent advances and technology breakthroughs Assesses realities of regulatory and cost hurdles Forward looking with coverage of small molecule technologies and the use of plants as models of human disease processes Providing wide-ranging and unique coverage, Molecular Pharming: Applications, Challenges and Emerging Areas will be of great interest to the plant science, plant biotechnology, protein science, and pharmacological communities.
Author: Paul Christou
Publisher: Springer
ISBN: 9781461457961
Category : Technology & Engineering
Languages : en
Pages : 1869
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Book Description
Gathering some 90 entries from the Encyclopedia of Sustainability Science and Technology, this book covers animal breeding and genetics for food, crop science and technology, ocean farming and sustainable aquaculture, transgenic livestock for food and more.
Author: Alexandra Castilho
Publisher: Humana
ISBN: 9781493927593
Category : Science
Languages : en
Pages : 0
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Book Description
Conceived with the intention of providing an array of strategies and technologies currently in use for glyco-engineering distinct living organisms, this book contains a wide range of methods being developed to control the composition of carbohydrates and the properties of proteins through manipulations on the production host rather than in the protein itself. The first five sections deal with host-specific glyco-engineering and contain chapters that provide protocols for modifications of the glycosylation pathway in bacteria, yeast, insect, plants and mammalian cells, while the last two sections explore alternative approaches to host glyco-engineering and selected protocols for the analysis of the N-glycans and glyco-profiling by mass spectrometry. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols and tips on troubleshooting and avoiding known pitfalls. Authoritative and extensive, Glyco-Engineering: Methods and Protocols offers vast options to help researchers to choose the expression system and approach that best suits their intended protein research or applications.
Author: Domenico De Martinis
Publisher: Frontiers Media SA
ISBN: 2889450511
Category :
Languages : en
Pages : 379
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Book Description
Plant gene transfer achieved in the early ‘80s paved the way for the exploitation of the potential of gene engineering to add novel agronomic traits and/or to design plants as factories for high added value molecules. For this latter area of research, the term "Molecular Farming" was coined in reference to agricultural applications in that major crops like maize and tobacco were originally used basically for pharma applications. The concept of the “green biofactory” implies different advantages over the typical cell factories based on animal cell or microbial cultures already when considering the investment and managing costs of fermenters. Although yield, stability, and quality of the molecules may vary among different heterologous systems and plants are competitive on a case-to-case basis, still the “plant factory” attracts scientists and technologists for the challenging features of low production cost, product safety and easy scale up. Once engineered, a plant is among the cheapest and easiest eukaryotic system to be bred with simple know-how, using nutrients, water and light. Molecules that are currently being produced in plants vary from industrial and pharmaceutical proteins, including medical diagnostics proteins and vaccine antigens, to nutritional supplements such as vitamins, carbohydrates and biopolymers. Convergence among disciplines as distant as plant physiology and pharmacology and, more recently, as omic sciences, bioinformatics and nanotechnology, increases the options of research on the plant cell factory. “Farming for Pharming” biologics and small-molecule medicines is a challenging area of plant biotechnology that may break the limits of current standard production technologies. The recent success on Ebola fighting with plant-made antibodies put a spotlight on the enormous potential of next generation herbal medicines made especially in the name of the guiding principle of reduction of costs, hence reduction of disparities of health rights and as a tool to guarantee adequate health protection in developing countries.
Author: Varsha Gupta
Publisher: Springer
ISBN: 9811008752
Category : Technology & Engineering
Languages : en
Pages : 543
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Book Description
This book explores the journey of biotechnology, searching for new avenues and noting the impressive accomplishments to date. It has harmonious blend of facts, applications and new ideas. Fast-paced biotechnologies are broadly applied and are being continuously explored in areas like the environmental, industrial, agricultural and medical sciences. The sequencing of the human genome has opened new therapeutic opportunities and enriched the field of medical biotechnology while analysis of biomolecules using proteomics and microarray technologies along with the simultaneous discovery and development of new modes of detection are paving the way for ever-faster and more reliable diagnostic methods. Life-saving bio-pharmaceuticals are being churned out at an amazing rate, and the unraveling of biological processes has facilitated drug designing and discovery processes. Advances in regenerative medical technologies (stem cell therapy, tissue engineering, and gene therapy) look extremely promising, transcending the limitations of all existing fields and opening new dimensions for characterizing and combating diseases.
Author: Vijai Singh
Publisher: Academic Press
ISBN: 0128214783
Category : Science
Languages : en
Pages : 490
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Book Description
Microbial Cell Factories Engineering for Production of Biomolecules presents a compilation of chapters written by eminent scientists worldwide. Sections cover major tools and technologies for DNA synthesis, design of biosynthetic pathways, synthetic biology tools, biosensors, cell-free systems, computer-aided design, OMICS tools, CRISPR/Cas systems, and many more. Although it is not easy to find relevant information collated in a single volume, the book covers the production of a wide range of biomolecules from several MCFs, including Escherichia coli, Bacillus subtilis, Pseudomonas putida, Streptomyces, Corynebacterium, Cyanobacteria, Saccharomyces cerevisiae, Pichia pastoris and Yarrowia lipolytica, and algae, among many others. This will be an excellent platform from which scientific knowledge can grow and widen in MCF engineering research for the production of biomolecules. Needless to say, the book is a valuable source of information not only for researchers designing cell factories, but also for students, metabolic engineers, synthetic biologists, genome engineers, industrialists, stakeholders and policymakers interested in harnessing the potential of MCFs in several fields. - Offers basic understanding and a clear picture of various MCFs - Explains several tools and technologies, including DNA synthesis, synthetic biology tools, genome editing, biosensors, computer-aided design, and OMICS tools, among others - Harnesses the potential of engineered MCFs to produce a wide range of biomolecules for industrial, therapeutic, pharmaceutical, nutraceutical and biotechnological applications - Highlights the advances, challenges, and future opportunities in designing MCFs
Author: Sumita Jha
Publisher:
ISBN: 9783319274904
Category : Botanical chemistry
Languages : en
Pages :
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Book Description
Author: Toyoki Kozai
Publisher: Academic Press
ISBN: 0128166924
Category : Technology & Engineering
Languages : en
Pages : 518
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Book Description
Plant Factory: An Indoor Vertical Farming System for Efficient Quality Food Production, Second Edition presents a comprehensive look at the implementation of plant factory (PF) practices to yield food crops for both improved food security and environmental sustainability. Edited and authored by leading experts in PF and controlled environment agriculture (CEA), the book is divided into five sections, including an Overview and the Concept of Closed Plant Production Systems (CPPS), the Basics of Physics and Physiology – Environments and Their Effects, System Design, Construction, Cultivation and Management and Plant Factories in Operation. In addition to new coverage on the rapid advancement of LED technology and its application in indoor vertical farming, other revisions to the new edition include updated information on the status of business R&D and selected commercial PFALs (plant factory with artificial lighting). Additional updates include those focused on micro and mini-PFALs for improving the quality of life in urban areas, the physics and physiology of light, the impact of PFAL on the medicinal components of plants, and the system design, construction, cultivation and management issues related to transplant production within closed systems, photoautotrophic micro-propagation and education, training and intensive business forums on PFs. - Includes coverage of LED technology - Presents case-studies for real-world insights and application - Addresses PF from economics and planning, to operation and lifecycle assessment
Author:
Publisher:
ISBN: 9783319320045
Category :
Languages : en
Pages :
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Book Description
