Author: Carla António
Publisher: Humana
ISBN: 9781493992942
Category : Science
Languages : en
Pages : 355
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Book Description
This detailed book aims to address the need for standardizing key steps in plant metabolomics research that is still considered a critical issue in the field. The collection unites diverse mass spectrometry (MS)-based protocols, from sample preparation and extraction of plant primary and secondary metabolites (e.g. a range of sugars, lipids, phytohormones and volatile organic compounds) to metabolite analysis, using exclusively highly sensitive MS-based methodologies, followed by frontline bioinformatics and/or mathematical modeling approaches to produce reliable biological data interpretation. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Plant Metabolomics: Methods and Protocols serves both new and well-established researchers in the plant metabolomics field in finding helpful guidelines and useful laboratory-based protocols for setting up their routine plant metabolomics experiments.
Author: Wolfram Weckwerth
Publisher: John Wiley & Sons
ISBN: 3527669906
Category : Science
Languages : en
Pages : 422
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Book Description
This is the newest title in the successful Molecular Plant Biology Handbook Series. Just like the other titles in the series this new book presents an excellent overview of different approaches and techniques in Metabolomics. Contributors are either from ivy-league research institutions or from companies developing new technologies in this dynamic and fast-growing field. With its approach to introduce current techniques in plant metabolomics to a wider audience and with many labs and companies considering to introduce metabolomics for their research, the title meets a growing market. The Kahl books are in addition a trusted brand for the plant science community and have always sold above expectations.
Author: Kazuki Saito
Publisher: Springer Science & Business Media
ISBN: 3540297820
Category : Science
Languages : en
Pages : 351
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Book Description
Metabolomics – which deals with all metabolites of an organism – is a rapidly-emerging sector of post-genome research fields. It plays significant roles in a variety of fields from medicine to agriculture and holds a fundamental position in functional genomics studies and their application in plant biotechnology. This volume comprehensively covers plant metabolomics for the first time. The chapters offer cutting-edge information on analytical technology, bioinformatics and applications. They were all written by leading researchers who have been directly involved in plant metabolomics research throughout the world. Up-to-date information and future developments are described, thereby producing a volume which is a landmark of plant metabolomics research and a beneficial guideline to graduate students and researchers in academia, industry, and technology transfer organizations in all plant science fields.
Author: B.J. Nikolau
Publisher: Springer
ISBN: 9789048111749
Category : Science
Languages : en
Pages : 298
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Book Description
Like genomics, which defines genes in a genome irrespective of functionality, metabolomics profiles all metabolites in a biological sample irrespective of the chemical and physical properties of these molecules. Metabolomics can potentially define cellular processes by providing a measure of the ultimate phenotype of an organism, characterized by the collage of small molecules whose levels of accumulation is altered in response to genetic and environmentally induced changes in gene expression.
Author: Sumira Jan
Publisher: Academic Press
ISBN: 012814873X
Category : Science
Languages : en
Pages : 404
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Book Description
Ecometabolomics: Metabolic Fluxes versus Environmental Stoichiometry focuses on the interaction between plants—particularly plants that have vigorous secondary metabolites—and the environment. The book offers a comprehensive overview of the responses of the metabolome of organisms to biotic and abiotic environmental changes. It includes an introduction to metabolomics, summaries of metabolomic techniques and applications, studies of stress in plants, and insights into challenges. This is a must-have reference for plant biologists, plant biochemists, plant ecologists and phytochemists researching the interface between plants and the environment using metabolomics. - Provides an in-depth overview of the basics of the discipline, including non-targeted analysis and quantification of plant metabolites - Outlines the applications of various analytical techniques in comprehending the total metabolome of the organism - Covers both NMR and MS-based approaches
Author: Nigel W. Hardy
Publisher: Springer Science+Business Media
ISBN: 9781617795947
Category : Science
Languages : en
Pages : 340
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Book Description
Estimating the metabolite complement of plant material involves a wide, and growing, range of techniques. This up-to-date guide provides stepwise, reproducible methodologies as well as key notes and implementation advice from experts in the field.
Author: John C. Lindon
Publisher: Elsevier
ISBN: 0080468004
Category : Science
Languages : en
Pages : 573
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Book Description
Molecular biology operates at three levels – genes, proteins and metabolites. This book is unique in that it provides a comprehensive description of an approach (metabonomics) to characterise the endogenous metabolites in a living system, complementing gene and protein studies (genomics and proteomics). These "omics" methods form the basis for understanding biology at a systems level. The Handbook of Metabonomics and Metabolomics aims to be the definitive work on the rapidly expanding subjects of metabolic profiling, metabolite and biomarker identification, encompassing the fields of metabonomics and metabolomics. It covers the principles of the subject, the analytical and statistical techniques used and the wide variety of applications.* comprehensive description of an approach (metabonomics) to characterise the endogenous metabolites in a living system, complementing gene and protein studies* aims to be the definitive work on the rapidly expanding subjects of metabolic profiling, metabolite and biomarker identification* covers the principles of the subject, the analytical and statistical techniques used and the wide variety of applications.
Author: Silas G. Villas-Boas
Publisher: John Wiley & Sons
ISBN: 047010550X
Category : Science
Languages : en
Pages : 339
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Book Description
Providing information on the main approaches for the analysis of metabolites, this textbook: Covers basic methodologies in sample preparation and separation techniques, as well as the most recent techniques of mass spectrometry. Differentiates between primary and secondary metabolites. Includes four chapters discussing successful metabolome studies of different organisms. Highlights the analytical challenges of studying metabolites. Illustrates applications of metabolome analysis through the use of case studies.
Author: George G. Harrigan
Publisher: Springer Science & Business Media
ISBN: 1461503337
Category : Science
Languages : en
Pages : 342
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Book Description
It is evident that biochemical control is not strictly hierarchical and that intermediary metabolism can contribute to control of regulatory pathways. Metabolic studies are therefore increasingly important in gene function analyses, and an increased interest in metabolites as biomarkers for disease progression or response to therapeutic intervention is also evident in the pharmaceutical industry. This book offers guidelines to currently available technology and bioinformatics and database strategies now being developed. Evidence is presented that metabolic profiling is a valuable addition to genomics and proteomics strategies devoted to drug discovery and development, and that metabolic profiling offers numerous advantages.
Author: Swapna Thacheril Sukumaran
Publisher: Springer Nature
ISBN: 9811551367
Category : Science
Languages : en
Pages : 594
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Book Description
Food security and the medicinal needs of billions of people around the world are pressing global issues, and the biodiversity and sustainable utilization of plants is of great significance in this context. Further, ethnobotanical studies are vital in the discovery of new drugs from indigenous medicinal plants, and plants with industrially important metabolites need to be cultivated to meet the growing market demand. In addition, the production of plant metabolites under in vitro conditions also has tremendous possibilities. The totipotency of plant cells plays a valuable role in the sustainable utilization of plant resources through cell, tissue and organ culture. At the same time, production can be enhanced using productive cell lines, treatment with elicitors, changing nutritional parameters and metabolic engineering. This book provides state-of-the-art information on biodiversity, conservation, ethnobotany, various aspects of In vitro secondary metabolite production, bioprospecting from various plant groups and drug discovery. It also discusses methods of extracting and characterizing drug leads from plant sources.
