Physiological Determinants of Exercise Tolerance in Humans PDF Download
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Author: Physiological Society (Great Britain)
Publisher: Ashgate Publishing
ISBN:
Category : Medical
Languages : en
Pages : 200
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Book Description
This work describes the physiological and biochemical responses to exercise. It examines the nature of the fatigue process and the adaptations which occur in response to training and how these responses are influenced by a variety of environmental factors.
Author: Physiological Society (Great Britain)
Publisher: Ashgate Publishing
ISBN:
Category : Medical
Languages : en
Pages : 200
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Book Description
This work describes the physiological and biochemical responses to exercise. It examines the nature of the fatigue process and the adaptations which occur in response to training and how these responses are influenced by a variety of environmental factors.
Author:
Publisher:
ISBN:
Category : Exercise
Languages : en
Pages : 0
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Book Description
Author: b; sargeant whipp (aj)
Publisher:
ISBN:
Category :
Languages : en
Pages :
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Book Description
Author: Jürgen M. Steinacker
Publisher: Springer Science & Business Media
ISBN: 1461558875
Category : Medical
Languages : en
Pages : 318
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Book Description
Proceedings of an international symposium, held in Ulm, Germany, September 21-24, 1994
Author: Physiological Society (Great Britain)
Publisher:
ISBN:
Category :
Languages : en
Pages : 46
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Book Description
Author: Michitoshi Inoue
Publisher: Springer Science & Business Media
ISBN: 4431683674
Category : Medical
Languages : en
Pages : 330
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Book Description
Research centering on blood flow in the heart continues to hold an important position, especially since a better understanding of the subject may help reduce the incidence of coronary arterial disease and heart attacks. This book summarizes recent advances in the field; it is the product of fruitful cooperation among international scientists who met in Japan in May, 1990 to discuss the regulation of coronary blood flow.
Author: Ryan M. Broxterman
Publisher:
ISBN:
Category :
Languages : en
Pages :
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Book Description
The physiological mechanisms determining the tolerable duration of exercise dictate human physical accomplishments across all spectrums of life. Despite extensive study, these specific mechanisms, and their dependence on oxygen delivery and oxygen utilization, remain, a certain extent, undefined. The purpose of this dissertation was to test the overarching hypothesis that muscle contraction characteristics (i.e., intensity of contraction, muscle contraction-relaxation duty cycle, etc.) alter oxygen delivery and oxygen utilization, which directly influence the power-duration relationship and fatigue development, and therefore, exercise tolerance. To accomplish this, specific interventions of altered muscle contraction-relaxation duty cycle and blood flow occlusion were utilized. In the first investigation (Chapter 2), we utilized low and high muscle contraction-relaxation duty cycles to alter blood flow to the active skeletal muscle, demonstrating that critical power (CP) was reduced with the high muscle contraction-relaxation duty cycle due to a reduction in blood flow, while the curvature constant (W') was not altered. The second investigation (Chapter 3) utilized blood flow occlusion to show that CP was reduced and W' increased for blood flow occlusion exercise conditions compared to control blood flow exercise conditions. The final investigation (Chapter 4) utilized periods of blood flow occlusion during and post-exercise to reveal greater magnitudes of peripheral and central fatigue development during blood flow occlusion exercise compared to control blood flow exercise. Moreover, this investigation demonstrated that W' was significantly related to the magnitude of fatigue development. Collectively, alterations in oxygen delivery and oxygen utilization via muscle contraction characteristics and blood flow occlusion directly influence CP and the magnitude of fatigue development. However, W' does not appear to be influenced by manipulations in oxygen delivery and oxygen utilization, per se. Rather, W' may be determined by the magnitude of fatigue accrued during exercise, which is dependent upon oxygen delivery and oxygen utilization. The novel findings of the investigations presented in this dissertation highlight important physiological mechanisms that determine exercise tolerance and demonstrate the need for interventions that improve oxygen delivery and oxygen utilization in specific populations, such as those with chronic heart failure or chronic obstructive pulmonary disease, to improve exercise tolerance.
Author: Ronald J. Korthuis
Publisher: Morgan & Claypool Publishers
ISBN: 1615041834
Category : Medical
Languages : en
Pages : 147
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Book Description
The aim of this treatise is to summarize the current understanding of the mechanisms for blood flow control to skeletal muscle under resting conditions, how perfusion is elevated (exercise hyperemia) to meet the increased demand for oxygen and other substrates during exercise, mechanisms underlying the beneficial effects of regular physical activity on cardiovascular health, the regulation of transcapillary fluid filtration and protein flux across the microvascular exchange vessels, and the role of changes in the skeletal muscle circulation in pathologic states. Skeletal muscle is unique among organs in that its blood flow can change over a remarkably large range. Compared to blood flow at rest, muscle blood flow can increase by more than 20-fold on average during intense exercise, while perfusion of certain individual white muscles or portions of those muscles can increase by as much as 80-fold. This is compared to maximal increases of 4- to 6-fold in the coronary circulation during exercise. These increases in muscle perfusion are required to meet the enormous demands for oxygen and nutrients by the active muscles. Because of its large mass and the fact that skeletal muscles receive 25% of the cardiac output at rest, sympathetically mediated vasoconstriction in vessels supplying this tissue allows central hemodynamic variables (e.g., blood pressure) to be spared during stresses such as hypovolemic shock. Sympathetic vasoconstriction in skeletal muscle in such pathologic conditions also effectively shunts blood flow away from muscles to tissues that are more sensitive to reductions in their blood supply that might otherwise occur. Again, because of its large mass and percentage of cardiac output directed to skeletal muscle, alterations in blood vessel structure and function with chronic disease (e.g., hypertension) contribute significantly to the pathology of such disorders. Alterations in skeletal muscle vascular resistance and/or in the exchange properties of this vascular bed also modify transcapillary fluid filtration and solute movement across the microvascular barrier to influence muscle function and contribute to disease pathology. Finally, it is clear that exercise training induces an adaptive transformation to a protected phenotype in the vasculature supplying skeletal muscle and other tissues to promote overall cardiovascular health. Table of Contents: Introduction / Anatomy of Skeletal Muscle and Its Vascular Supply / Regulation of Vascular Tone in Skeletal Muscle / Exercise Hyperemia and Regulation of Tissue Oxygenation During Muscular Activity / Microvascular Fluid and Solute Exchange in Skeletal Muscle / Skeletal Muscle Circulation in Aging and Disease States: Protective Effects of Exercise / References
Author: Manfred Lamprecht
Publisher: CRC Press
ISBN: 1466567570
Category : Medical
Languages : en
Pages : 304
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Book Description
The use of antioxidants in sports is controversial due to existing evidence that they both support and hinder athletic performance. Antioxidants in Sport Nutrition covers antioxidant use in the athlete ́s basic nutrition and discusses the controversies surrounding the usefulness of antioxidant supplementation. The book also stresses how antioxidants may affect immunity, health, and exercise performance. The book contains scientifically based chapters explaining the basic mechanisms of exercise-induced oxidative damage. Also covered are methodological approaches to assess the effectiveness of antioxidant treatment. Biomarkers are discussed as a method to estimate the bioefficacy of dietary/supplemental antioxidants in sports. This book is useful for sport nutrition scientists, physicians, exercise physiologists, product developers, sport practitioners, coaches, top athletes, and recreational athletes. In it, they will find objective information and practical guidance.
Author: Jerzy A. Zoladz
Publisher: Academic Press
ISBN: 0128145943
Category : Science
Languages : en
Pages : 619
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Book Description
Muscle and Exercise Physiology is a comprehensive reference covering muscle and exercise physiology, from basic science to advanced knowledge, including muscle power generating capabilities, muscle energetics, fatigue, aging and the cardio-respiratory system in exercise performance. Topics presented include the clinical importance of body responses to physical exercise, including its impact on oxygen species production, body immune system, lipid and carbohydrate metabolism, cardiac energetics and its functional reserves, and the health-related effects of physical activity and inactivity. Novel topics like critical power, ROS and muscle, and heart muscle physiology are explored. This book is ideal for researchers and scientists interested in muscle and exercise physiology, as well as students in the biological sciences, including medicine, human movements and sport sciences. - Contains basic and state-of-the-art knowledge on the most important issues of muscle and exercise physiology, including muscle and body adaptation to physical training, the impact of aging and physical activity/inactivity - Provides both the basic and advanced knowledge required to understand mechanisms that limit physical capacity in both untrained people and top class athletes - Covers advanced content on muscle power generating capabilities, muscle energetics, fatigue and aging
