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Author: Kazuo Ohki
Publisher: Springer
ISBN: 4431568417
Category : Science
Languages : en
Pages : 170
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Book Description
This book describes how biologically available free energy sources (ATP, chemical potential, and membrane potentials, among others) can be used to drive synthetic reactions, signaling in cells, and various types of motion such as membrane traffic, active transport, and cell locomotion. As such, it approaches the concept of the energy cycle of life on Earth from a physical point of view, covering topics ranging from an introduction to chemical evolution, to an examination of the catalytic activity of enzymes associated with the genome in Darwinian evolution. The author introduces the relationship between functions and physical properties in biomembranes, explaining the methods and equipment used in biophysics research to help researchers unravel the still-unsolved mysteries of life. The physical principles needed to understand the cellular functions are provided; these functions are associated with biomembranes and regulated by physical properties of the lipid bilayer such as membrane fluidity, phase transition, and phase separation, as shown in lipid rafts. Other key dynamic aspects of life (cell locomotion, cytoskeletal dynamics, and sensitivities of the cell to physical stimuli such as external forces and temperature) are also discussed. Lastly, readers will learn how life on Earth and its ecological system are maintained by solar energy, and be provided further information on the problems accompanying global warming.
Author: Kazuo Ohki
Publisher: Springer
ISBN: 4431568417
Category : Science
Languages : en
Pages : 170
Get Book Here
Book Description
This book describes how biologically available free energy sources (ATP, chemical potential, and membrane potentials, among others) can be used to drive synthetic reactions, signaling in cells, and various types of motion such as membrane traffic, active transport, and cell locomotion. As such, it approaches the concept of the energy cycle of life on Earth from a physical point of view, covering topics ranging from an introduction to chemical evolution, to an examination of the catalytic activity of enzymes associated with the genome in Darwinian evolution. The author introduces the relationship between functions and physical properties in biomembranes, explaining the methods and equipment used in biophysics research to help researchers unravel the still-unsolved mysteries of life. The physical principles needed to understand the cellular functions are provided; these functions are associated with biomembranes and regulated by physical properties of the lipid bilayer such as membrane fluidity, phase transition, and phase separation, as shown in lipid rafts. Other key dynamic aspects of life (cell locomotion, cytoskeletal dynamics, and sensitivities of the cell to physical stimuli such as external forces and temperature) are also discussed. Lastly, readers will learn how life on Earth and its ecological system are maintained by solar energy, and be provided further information on the problems accompanying global warming.
Author: Coral Gables Conference on Physical Principles of Biological Membranes (1968 : University of Miami)
Publisher:
ISBN:
Category :
Languages : en
Pages : 0
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Book Description
Author: Patricia Bassereau
Publisher: Springer
ISBN: 3030006301
Category : Science
Languages : en
Pages : 623
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Book Description
This book mainly focuses on key aspects of biomembranes that have emerged over the past 15 years. It covers static and dynamic descriptions, as well as modeling for membrane organization and shape at the local and global (at the cell level) scale. It also discusses several new developments in non-equilibrium aspects that have not yet been covered elsewhere. Biological membranes are the seat of interactions between cells and the rest of the world, and internally, they are at the core of complex dynamic reorganizations and chemical reactions. Despite the long tradition of membrane research in biophysics, the physics of cell membranes as well as of biomimetic or synthetic membranes is a rapidly developing field. Though successful books have already been published on this topic over the past decades, none include the most recent advances. Additionally, in this domain, the traditional distinction between biological and physical approaches tends to blur. This book gathers the most recent advances in this area, and will benefit biologists and physicists alike.
Author: Mohammad Ashrafuzzaman
Publisher: Springer Science & Business Media
ISBN: 3642161057
Category : Science
Languages : en
Pages : 190
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Book Description
Physics, mathematics and chemistry all play a vital role in understanding the true nature and functioning of biological membranes, key elements of living processes. Besides simple spectroscopic observations and electrical measurements of membranes we address in this book the phenomena of coexistence and independent existence of different membrane components using various theoretical approaches. This treatment will be helpful for readers who want to understand biological processes by applying both simple observations and fundamental scientific analysis. It provides a deep understanding of the causes and effects of processes inside membranes, and will thus eventually open new doors for high-level pharmaceutical approaches towards fighting membrane- and cell-related diseases.
Author: Stephen H White
Publisher: Garland Science
ISBN: 1000508536
Category : Medical
Languages : en
Pages : 565
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Book Description
The central themes of Cell Boundaries concern the structural and organizational principles underlying cell membranes, and how these principles enable function. By building a biological and biophysical foundation for understanding the organization of lipids in bilayers and the folding, assembly, stability, and function of membrane proteins, the book aims to broaden the knowledge of bioscience students to include the basic physics and physical chemistry that inform us about membranes. In doing so, it is hoped that physics students will find familiar territory that will lead them to an interest in biology. Our progress toward understanding membranes and membrane proteins depends strongly upon the concerted use of both biology and physics. It is important for students to know not only what we know, but how we have come to know it, so Cell Boundaries endeavours to bring out the history behind the central discoveries, especially in the early chapters, where the foundation is laid for later chapters. Science is far more interesting if, as students, we can appreciate and share in the adventures—and misadventures—of discovering new scientific knowledge. Cell Boundaries was written with advanced undergraduates and beginning graduate students in the biological and physical sciences in mind, though this textbook will likely have appeal to researchers and other academics as well. Highlights the history of important central discoveries Early chapters lay the foundation for later chapters to build on, so knowledge is amassed High-quality line diagrams illustrate key concepts and illuminate molecular mechanisms Box features and spreads expand on topics in main text, including histories of discoveries, special techniques, and applications
Author: Bruce Alberts
Publisher:
ISBN: 9780815332183
Category : Cytology
Languages : en
Pages : 0
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Book Description
Author: R. Lipowsky
Publisher: Elsevier
ISBN: 0080541917
Category : Technology & Engineering
Languages : en
Pages : 537
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Book Description
The first volume of the Handbook deals with the amazing world of biomembranes and lipid bilayers. Part A describes all aspects related to the morphology of these membranes, beginning with the complex architecture of biomembranes, continues with a description of the bizarre morphology of lipid bilayers and concludes with technological applications of these membranes. The first two chapters deal with biomembranes, providing an introduction to the membranes of eucaryotes and a description of the evolution of membranes. The following chapters are concerned with different aspects of lipids including the physical properties of model membranes composed of lipid-protein mixtures, lateralphase separation of lipids and proteins and measurement of lipid-protein bilayer diffusion. Other chapters deal with the flexibility of fluid bilayers, the closure of bilayers into vesicles which attain a large variety of different shapes, and applications of lipid vesicles and liposomes. Part B covers membrane adhesion, membrane fusion and the interaction of biomembranes withpolymer networks such as the cytoskeleton. The first two chapters of this part discuss the generic interactions of membranes from the conceptual point of view. The following two chapters summarize the experimental work on two different bilayer systems. The next chapter deals with the process ofcontact formation, focal bounding and macroscopic contacts between cells. The cytoskeleton within eucaryotic cells consists of a network of relatively stiff filaments of which three different types of filaments have been identified. As explained in the next chapter much has been recently learned aboutthe interaction of these filaments with the cell membrane. The final two chapters deal with membrane fusion.
Author: Coral Gables Conference on Physical Principles of Biological Membranes (1968 : University of Miami)
Publisher:
ISBN:
Category :
Languages : en
Pages :
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Book Description
Author: John Stephen White
Publisher: Garland Science
ISBN: 9781000508611
Category : Medical
Languages : en
Pages : 546
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Book Description
The central themes of Cell Boundaries concern the structural and organizational principles underlying cell membranes, and how these principles enable function. By building a biological and biophysical foundation for understanding the organization of lipids in bilayers and the folding, assembly, stability, and function of membrane proteins, the book aims to broaden the knowledge of bioscience students to include the basic physics and physical chemistry that inform us about membranes. In doing so, it is hoped that physics students will find familiar territory that will lead them to an interest in biology. Our progress toward understanding membranes and membrane proteins depends strongly upon the concerted use of both biology and physics. It is important for students to know not only what we know, but how we have come to know it, so Cell Boundaries endeavours to bring out the history behind the central discoveries, especially in the early chapters, where the foundation is laid for later chapters. Science is far more interesting if, as students, we can appreciate and share in the adventures--and misadventures--of discovering new scientific knowledge. Cell Boundaries was written with advanced undergraduates and beginning graduate students in the biological and physical sciences in mind, though this textbook will likely have appeal to researchers and other academics as well. Highlights the history of important central discoveries Early chapters lay the foundation for later chapters to build on, so knowledge is amassed High-quality line diagrams illustrate key concepts and illuminate molecular mechanisms Box features and spreads expand on topics in main text, including histories of discoveries, special techniques, and applications
Author: Cecilia Hidalgo
Publisher: Springer Science & Business Media
ISBN: 1461309352
Category : Science
Languages : en
Pages : 242
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Book Description
This book was originated from a series of lectures given in a course on the physical properties of biological membranes and their functional implica tions. The course was intended to allow students to get acquainted with the physical techniques used to study biological membranes. The experience was valuable and we feel that a detailed description of the procedures used and of various examples of the results obtained allowed many students to become familiar with a theme that is not often part of regular courses on membrane physiology or biophysics. This book is designed as a tutorial guide for graduate students interested in understanding how physical methods can be utilized to study the proper ties of biological membranes. It includes first a detailed description of applications of physical techniques-such as X-ray fiber diffraction methods (Chapter 1), 2H and 13C NMR spectroscopy (Chapter 2), and calorimetry (Chapter 3)-in the study of the properties of lipid model membranes. A description of how to measure molecular mobility in membranes (Chapter 4) follows, and the book concludes with three chapters in which biological membranes are the subject of study. Chapter 5 deals with the acetylcholine receptor and its membrane environment; Chapter 6 discusses how fluorescence techniques can be applied in the study of the calcium ATPase of sarcoplasmic reticulum; and Chapter 7 explains how protein lipid interactions modulate the function of the sodium and proton pumps.
