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Author: National Research Council
Publisher: National Academies Press
ISBN: 0309128412
Category : Nature
Languages : en
Pages : 208
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Book Description
People are exposed to a variety of chemicals throughout their daily lives. To protect public health, regulators use risk assessments to examine the effects of chemical exposures. This book provides guidance for assessing the risk of phthalates, chemicals found in many consumer products that have been shown to affect the development of the male reproductive system of laboratory animals. Because people are exposed to multiple phthalates and other chemicals that affect male reproductive development, a cumulative risk assessment should be conducted that evaluates the combined effects of exposure to all these chemicals. The book suggests an approach for cumulative risk assessment that can serve as a model for evaluating the health risks of other types of chemicals.
Author: National Research Council
Publisher: National Academies Press
ISBN: 0309128412
Category : Nature
Languages : en
Pages : 208
Get Book Here
Book Description
People are exposed to a variety of chemicals throughout their daily lives. To protect public health, regulators use risk assessments to examine the effects of chemical exposures. This book provides guidance for assessing the risk of phthalates, chemicals found in many consumer products that have been shown to affect the development of the male reproductive system of laboratory animals. Because people are exposed to multiple phthalates and other chemicals that affect male reproductive development, a cumulative risk assessment should be conducted that evaluates the combined effects of exposure to all these chemicals. The book suggests an approach for cumulative risk assessment that can serve as a model for evaluating the health risks of other types of chemicals.
Author: National Academies of Sciences, Engineering, and Medicine
Publisher: National Academies Press
ISBN: 0309458625
Category : Science
Languages : en
Pages : 423
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Book Description
To safeguard public health, the US Environmental Protection Agency (EPA) must keep abreast of new scientific information and emerging technologies so that it can apply them to regulatory decision-making. For decades the agency has dealt with questions about what animal-testing data to use to make predictions about human health hazards, how to perform dose-response extrapolations, how to identify and protect susceptible subpopulations, and how to address uncertainties. As alternatives to traditional toxicity testing have emerged, the agency has been faced with additional questions about how to incorporate data from such tests into its chemical assessments and whether such tests can replace some traditional testing methods. Endocrine active chemicals (EACs) have raised concerns that traditional toxicity-testing protocols might be inadequate to identify all potential hazards to human health because they have the ability to modulate normal hormone function, and small alterations in hormone concentrations, particularly during sensitive life stages, can have lasting and significant effects. To address concerns about potential human health effects from EACs at low doses, this report develops a strategy to evaluate the evidence for such low-dose effects.
Author: Bradley C. Vaughn
Publisher:
ISBN: 9781607417019
Category : Bisphenol A
Languages : en
Pages : 0
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Book Description
Bisphenol A is a difunctional building block of several important plastics and plastic additives. Suspected of being hazardous to humans since the 1930s, concerns about the use of bisphenol A in consumer products were regularly reported in the news media in 2008 after several governments issued reports questioning its safety, causing some retailers to remove products made of it from their shelves. Additionally, phthalates, are esters of phthalic acid and are mainly used as plasticisers (substances added to plastics to increase their flexibility, transparency, durability, and longevity). They are primarily used to soften polyvinyl chloride. This book examines both bisphenol A and phthalates discussing and presenting numerous topical and related data on these compounds and their uses, health effects and environmental risks.
Author: Charles Staples
Publisher: Springer
ISBN: 3540366113
Category : Science
Languages : en
Pages : 362
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Book Description
Phthalate esters are an important class of chemicals widely used in commercial applications, primarily as plasticizers to soften vinyl, but they are also used in consumer products. This book reviews the state of the scientific knowledge of phthalate esters in the environment. Key information reported includes: analytical methodologies; a compilation of concentration measurements in water, sediment, soil, air, dust, and food; plus an assessment of critical exposure pathways. In addition, key physical properties data and fate characteristics that control exposure are reviewed. Also included are pertinent ecotoxicity data and mammalian toxicity and human health information. Finally, the monograph addresses potential environmental risks.
Author: Charles Staples
Publisher: Springer Science & Business Media
ISBN: 9783540009924
Category : Science
Languages : en
Pages : 376
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Book Description
Phthalate esters are an important class of chemicals widely used in commercial applications, primarily as plasticizers to soften vinyl, but they are also used in consumer products. This book reviews the state of the scientific knowledge of phthalate esters in the environment. Key information reported includes: analytical methodologies; a compilation of concentration measurements in water, sediment, soil, air, dust, and food; plus an assessment of critical exposure pathways. In addition, key physical properties data and fate characteristics that control exposure are reviewed. Also included are pertinent ecotoxicity data and mammalian toxicity and human health information. Finally, the monograph addresses potential environmental risks.
Author: Shanna H. Swan
Publisher: Simon and Schuster
ISBN: 1982113677
Category : Health & Fitness
Languages : en
Pages : 304
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Book Description
An award-winning scientist, in this urgent, thought-provoking and meticulously researched book, shows how chemicals in the modern environment are changing--and endangering--human sexuality and fertility on the grandest scale.
Author: Gerardo L. Moretti
Publisher:
ISBN: 9781620819944
Category : Phthalate esters
Languages : en
Pages : 0
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Book Description
Phthalates are esters of phthalic acid and are a group of chemicals of high environmental relevance due to their production rates and ecotoxicological potential. Phthalates are mainly used as plasticizers in PVC plastics, wherein many consumer products contain specific members of this family of chemicals. In this book, the authors present current research on the chemical properties and impacts on health and the environment of phthalates. Topics include phthalate contamination in two estuaries from the Basque Coast; bioaccumulation and intracellular signal modifications of in vivo and in vitro models of phthalate esters; DEHP behavior in contact with liquid food simulants, blood, saliva and soil; removal of phthalates from the environment; gas phase fragmentation reactions of phthalate ions; the effects of DEHP exposure on brain development; and phthalate toxicogenomics and health effects.
Author:
Publisher:
ISBN:
Category : Diethylhexyl phthalate
Languages : en
Pages : 318
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Book Description
Author: Khursheed Ahmad Wani
Publisher: IGI Global, Engineering Science Reference
ISBN: 9781522594550
Category : Medical
Languages : en
Pages : 0
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Book Description
"This book examines the negative impacts of plastic and explores different biotechnological interventions to plastic pollution. It also generates an awareness of the use of plastics and its impact on the environment, human health, and other ecosystems"--
Author: Miguel Owens
Publisher: Nova Science Publishers
ISBN: 9781634839082
Category : Esters
Languages : en
Pages : 0
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Book Description
Phthalates are ester derivatives that have been used to alter the flexibility of plastics since the 1930s, and are ubiquitous in our daily life. The first chapter of this book discusses how perinatal exposure to phthalates may induce alterations in brain neural growth and differentiation, with neurocognitive and behavioral consequences. Chapter two investigates the advantages and/or disadvantages of some analytical methods used in the past few years for chromatographic detection. The fourth chapter discusses the widespread application of phthalates and the role of liquid chromatography-mass spectrometry technique used in the detection, determination and confirmation of the chemical. The final chapter examines the assessment of phthalate exposure in polymer materials with advanced numerical algorithms.
