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Author: Charles Staples
Publisher: Springer
ISBN: 3540366113
Category : Science
Languages : en
Pages : 362
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Book Description
Phthalate esters are an important class of chemicals widely used in commercial applications, primarily as plasticizers to soften vinyl, but they are also used in consumer products. This book reviews the state of the scientific knowledge of phthalate esters in the environment. Key information reported includes: analytical methodologies; a compilation of concentration measurements in water, sediment, soil, air, dust, and food; plus an assessment of critical exposure pathways. In addition, key physical properties data and fate characteristics that control exposure are reviewed. Also included are pertinent ecotoxicity data and mammalian toxicity and human health information. Finally, the monograph addresses potential environmental risks.
Author: Charles Staples
Publisher: Springer
ISBN: 3540366113
Category : Science
Languages : en
Pages : 362
Get Book Here
Book Description
Phthalate esters are an important class of chemicals widely used in commercial applications, primarily as plasticizers to soften vinyl, but they are also used in consumer products. This book reviews the state of the scientific knowledge of phthalate esters in the environment. Key information reported includes: analytical methodologies; a compilation of concentration measurements in water, sediment, soil, air, dust, and food; plus an assessment of critical exposure pathways. In addition, key physical properties data and fate characteristics that control exposure are reviewed. Also included are pertinent ecotoxicity data and mammalian toxicity and human health information. Finally, the monograph addresses potential environmental risks.
Author: Charles Staples
Publisher: Springer Science & Business Media
ISBN: 9783540009924
Category : Science
Languages : en
Pages : 376
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Book Description
Phthalate esters are an important class of chemicals widely used in commercial applications, primarily as plasticizers to soften vinyl, but they are also used in consumer products. This book reviews the state of the scientific knowledge of phthalate esters in the environment. Key information reported includes: analytical methodologies; a compilation of concentration measurements in water, sediment, soil, air, dust, and food; plus an assessment of critical exposure pathways. In addition, key physical properties data and fate characteristics that control exposure are reviewed. Also included are pertinent ecotoxicity data and mammalian toxicity and human health information. Finally, the monograph addresses potential environmental risks.
Author: Philippa D. Darbre
Publisher: Academic Press
ISBN: 0128219882
Category : Medical
Languages : en
Pages : 536
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Book Description
**Selected for Doody's Core Titles® 2024 in Endocrinology/Metabolic Disease** Updated with new and expanded chapters, Endocrine Disruption and Human Health, Second Edition provides an introduction to what endocrine disruptors are, the issues surrounding them, the source of these chemicals in the ecosystem and the mechanisms of action and assay systems. Contributions by specialists are included to discuss the varying effects of endocrine disruption on human health, and procedures for risk assessment of endocrine disruptors, and current approaches to their regulation are also covered. With new material on topics such as low-term, low dose mixtures, windows of susceptibility, epigenetics, EDCs effect on the gut microbiome, EDCs in from polluted air and oral exposures, green chemistry, and nanotechnology, the new edition of Endocrine Disruption and Human Health is a valuable and informative text for academic and clinical researchers and other health professionals approaching endocrine disruption and its effects on human health for the first time, graduate students, and advanced undergraduate students. - Provides readers with access to a range of information from the basic mechanisms and assays through to cutting-edge research investigating concerns for human health - Presents a comprehensive, translational look at all aspects of endocrine disruption and its effects on human health - Offers guidance on the risk assessment of endocrine disruptors and current relevant regulatory considerations - Newly added content on topics like low-term, low dose mixtures, windows of susceptibility to EDCs, EDCs effect on the gut microbiome, green chemistry, and nanotechnology
Author: Suresh C Sikka
Publisher: Academic Press
ISBN: 0128013133
Category : Medical
Languages : en
Pages : 638
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Book Description
Bioenvironmental Issues Affecting Men's Reproductive and Sexual Health is structured into two parts related to men's reproductive and sexual health with eight sections designed to enable a logical flow of such knowledge. The book is focused on the biology of key organs involved in male reproduction and the environmental influences affecting their functions with particular emphasis on clinical aspects. Individual chapters within the book range from basic to translational aspects, but all hold clinical relevance. This is an essential reference for those working and learning in the field of human reproduction, reproductive toxicology and environmental influences on reproductive and sexual health. - Brings together the leading authorities working in the field of male reproduction and sexual health and how the environment affects these issues - Provides guidelines and reference values of various reproductive hormones, semen parameters, inclusion/exclusion criteria for clinical trials - Discover the most efficient methods by which to design clinical protocols for sperm safety studies and reproductive toxicology trials
Author: National Research Council
Publisher: National Academies Press
ISBN: 0309128412
Category : Nature
Languages : en
Pages : 208
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Book Description
People are exposed to a variety of chemicals throughout their daily lives. To protect public health, regulators use risk assessments to examine the effects of chemical exposures. This book provides guidance for assessing the risk of phthalates, chemicals found in many consumer products that have been shown to affect the development of the male reproductive system of laboratory animals. Because people are exposed to multiple phthalates and other chemicals that affect male reproductive development, a cumulative risk assessment should be conducted that evaluates the combined effects of exposure to all these chemicals. The book suggests an approach for cumulative risk assessment that can serve as a model for evaluating the health risks of other types of chemicals.
Author: Marcelo Larramendy
Publisher: BoD – Books on Demand
ISBN: 953512160X
Category : Science
Languages : en
Pages : 242
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Book Description
This edited book, Emerging Pollutants in the Environment Current and Further Implications, includes overviews by significant researchers on the topic of emerging pollutants toxicology, which covers the hazardous effects of common emerging xenobiotics employed in our every day anthropogenic activities. We hope that this book will meet the expectations and needs of all those who are interested in the negative implications of several emerging pollutants on living species.
Author: Melanie Bergmann
Publisher: Springer
ISBN: 3319165100
Category : Science
Languages : en
Pages : 456
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Book Description
This book describes how man-made litter, primarily plastic, has spread into the remotest parts of the oceans and covers all aspects of this pollution problem from the impacts on wildlife and human health to socio-economic and political issues. Marine litter is a prime threat to marine wildlife, habitats and food webs worldwide. The book illustrates how advanced technologies from deep-sea research, microbiology and mathematic modelling as well as classic beach litter counts by volunteers contributed to the broad awareness of marine litter as a problem of global significance. The authors summarise more than five decades of marine litter research, which receives growing attention after the recent discovery of great oceanic garbage patches and the ubiquity of microscopic plastic particles in marine organisms and habitats. In 16 chapters, authors from all over the world have created a universal view on the diverse field of marine litter pollution, the biological impacts, dedicated research activities, and the various national and international legislative efforts to combat this environmental problem. They recommend future research directions necessary for a comprehensive understanding of this environmental issue and the development of efficient management strategies. This book addresses scientists, and it provides a solid knowledge base for policy makers, NGOs, and the broader public.
Author: Gerardo L. Moretti
Publisher:
ISBN: 9781620819944
Category : Phthalate esters
Languages : en
Pages : 0
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Book Description
Phthalates are esters of phthalic acid and are a group of chemicals of high environmental relevance due to their production rates and ecotoxicological potential. Phthalates are mainly used as plasticizers in PVC plastics, wherein many consumer products contain specific members of this family of chemicals. In this book, the authors present current research on the chemical properties and impacts on health and the environment of phthalates. Topics include phthalate contamination in two estuaries from the Basque Coast; bioaccumulation and intracellular signal modifications of in vivo and in vitro models of phthalate esters; DEHP behavior in contact with liquid food simulants, blood, saliva and soil; removal of phthalates from the environment; gas phase fragmentation reactions of phthalate ions; the effects of DEHP exposure on brain development; and phthalate toxicogenomics and health effects.
Author: National Academies of Sciences, Engineering, and Medicine
Publisher: National Academies Press
ISBN: 0309458625
Category : Science
Languages : en
Pages : 423
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Book Description
To safeguard public health, the US Environmental Protection Agency (EPA) must keep abreast of new scientific information and emerging technologies so that it can apply them to regulatory decision-making. For decades the agency has dealt with questions about what animal-testing data to use to make predictions about human health hazards, how to perform dose-response extrapolations, how to identify and protect susceptible subpopulations, and how to address uncertainties. As alternatives to traditional toxicity testing have emerged, the agency has been faced with additional questions about how to incorporate data from such tests into its chemical assessments and whether such tests can replace some traditional testing methods. Endocrine active chemicals (EACs) have raised concerns that traditional toxicity-testing protocols might be inadequate to identify all potential hazards to human health because they have the ability to modulate normal hormone function, and small alterations in hormone concentrations, particularly during sensitive life stages, can have lasting and significant effects. To address concerns about potential human health effects from EACs at low doses, this report develops a strategy to evaluate the evidence for such low-dose effects.
Author: Francis A. Gunther
Publisher: Springer
ISBN: 9781461584605
Category : Science
Languages : en
Pages : 169
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Book Description
That residues of pesticide and other "foreign" chemicals in food stuffs are of concern to everyone everywhere is amply attested by the reception accorded previous volumes of "Residue Reviews" and by the gratifying enthusiasm, sincerity, and efforts shown by all the in dividuals from whom manuscripts have been solicited. Despite much propaganda to the contrary, there can never be any serious question that pest-control chemicals and food-additive chemicals are essential to adequate food production, manufacture, marketing, and storage, yet without continuing surveillance and intelligent control some of those that persist in our foodstuffs could at times conceivably endanger the public health. Ensuring safety-in-use of these many chemicals is a dynamic challenge, for established ones are continually being dis placed by newly developed ones more acceptable to food technologists, pharmacologists, taxicologists, and changing pest-control requirements in progressive food-producing economies. These matters are of genuine concern to increasing numbers of governmental agencies and legislative bodies around the world, for some of these chemicals have resulted in a few mishaps from improper use. Adequate safety-in-use evaluations of any of these chemicals per sisting into our foodstuffs are not simple matters, and they incorporate the considered judgments of many individuals highly trained in a variety of complex biological, chemical, food technological, medical, pharmacological, and toxicological disciplines.
