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Author: Avital Schurr
Publisher: CRC Press
ISBN: 9780849367151
Category : Science
Languages : en
Pages : 456
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Book Description
This fascinating monograph is filled with information formerly found only in periodicals and symposia proceedings. Chapters discuss the different models of cerebral ischemia in use today, including their advantages and disadvantages. This one-of-a-kind resource also contains essential chapters on cellular mechanisms of ion and acid-base homeostases, and energy metabolism of the ischemic brain. It reviews the possible role of lipids, free fatty acids, and free radicals. Four chapters are devoted to neurotransmitters and neuroregulators in cerebral ischemia. This extraordinary work also covers aspects of protection against and resuscitation from cerebral ischemia. An extremely informative volume, this book is an absolute must for every student in the field of cerebral ischemia, as well as the clinician or scientist who is already involved with this worldwide problem.
Author: Avital Schurr
Publisher: CRC Press
ISBN: 9780849367151
Category : Science
Languages : en
Pages : 456
Get Book Here
Book Description
This fascinating monograph is filled with information formerly found only in periodicals and symposia proceedings. Chapters discuss the different models of cerebral ischemia in use today, including their advantages and disadvantages. This one-of-a-kind resource also contains essential chapters on cellular mechanisms of ion and acid-base homeostases, and energy metabolism of the ischemic brain. It reviews the possible role of lipids, free fatty acids, and free radicals. Four chapters are devoted to neurotransmitters and neuroregulators in cerebral ischemia. This extraordinary work also covers aspects of protection against and resuscitation from cerebral ischemia. An extremely informative volume, this book is an absolute must for every student in the field of cerebral ischemia, as well as the clinician or scientist who is already involved with this worldwide problem.
Author: Alexander Hartmann
Publisher: Springer Science & Business Media
ISBN: 3642781519
Category : Medical
Languages : en
Pages : 447
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Book Description
In this volume, one of a series of monographs devoted to the problems of cerebral ischemia and related topics, we present the proceedings of an international conference on Cerebral Ischemia and Basic Mechanisms held in Bad Schachen/Lake Constance, Germany in June 1992. The enormous progress in research recently on the basic mechanisms associated with cerebral ischemia has provided greater insight into the pathophysiological mechanisms of reduced brain perfusion and decreased cerebral metabolism. The high technology instrumentation used to unravel the intricacies of cerebral blood flow and metabolism includes positron emission tomography and magnetic resonance imaging. A description of sophisticated neurophysiological techniques will give the reader insight into new models of reversible and irreversible tissue damage and changes at the molecular level have been described. The therapeutic approaches which have developed from this re search have been or will be used in clinical trials and will open new avenues in the treatment of stroke. The organizers of the meeting would like to thank the advisory board for its helpful suggestions and the Deutsche Forschungsgemeinschaft and other sponsors for their important support.
Author: National Library of Medicine (U.S.)
Publisher:
ISBN:
Category : Medicine
Languages : en
Pages : 1024
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Book Description
First multi-year cumulation covers six years: 1965-70.
Author: Nicolas G. Bazan
Publisher: Springer Science & Business Media
ISBN: 1461533120
Category : Medical
Languages : en
Pages : 378
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Book Description
In this timely volume, eminent researchers provide detailed coverage of the relevant function of neurochemical correlates to cerebral ischemia as well as their pathophysiological significance.
Author: Gert J. Ter Horst
Publisher: Springer Science & Business Media
ISBN: 1592594727
Category : Medical
Languages : en
Pages : 309
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Book Description
A distinguished international panel of authors define our current understanding of neuronal damage after ischemia and critically review the significant recent developments and progress in cerebrovascular accident (CVA) drug trials, both in animal models and in the clinical setting. These leading basic and fundamental authorities survey such important new drugs as calcium-influx inhibitors, free-radical scavenging drugs, glutamate and glycinergic antagonists, and immune suppressors. They also evaluate all the latest findings concerning calcium homeostasis, glutamate toxicity, gene activation, and the role of free radicals, glycine, and hormones. Chapters devoted to the neuroimaging of stroke, clinical trials, and the role of cerebral immune activation complete this informative collection of cutting-edge reviews.
Author: National Library of Medicine (U.S.)
Publisher:
ISBN:
Category : Medicine
Languages : en
Pages : 1178
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Book Description
Author: Alexander Hartmann
Publisher: Springer Science & Business Media
ISBN: 3642762085
Category : Medical
Languages : en
Pages : 460
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Book Description
In contrast to dementia of the Alzheimer type, the subject of dementia subsequent to cerebral ischemia has been discussed rather rarely. Now this book provides a summary of the brain morphology, neurochemistry and clinical aspects of dementia subsequent to cerebral ischemia. The contributions discuss the similarities and differences between the two predominant dementia types. The broad range of aspects cover 1) the morphology and morphobiology of brain tissue during aging and under the two pathological condi- tions, 2) the neuropathochemistry of post mortem brain tissue of patients as well as brain tissue from experimental animals, 3) CSF changes during aging and in dementia states and 4) clinical research, mainly using brain imaging tech- niques to differentiate between dementia types and to find a basis for rational therapeutic approaches.
Author: U. Ito
Publisher: Springer Science & Business Media
ISBN: 3642771343
Category : Medical
Languages : en
Pages : 294
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Book Description
It has been well recognized that following an ischemic insult many nerve cells of the brain are not killed outright, but may suffer a "delayed neuronal death" or even recover. This led to the concept of "maturation phenomenon" with its main implication that the maturation of ischemic lesions may provide a "window of opportunity" i.e. a period of time when the injury to neuronal elements is still reversible, and during which an application of proper therapeutic measures might be successful. The symposium on Maturation Phenomenon in Cerebral Ischemia was the first international meeting focussed primarily on this subject and the resulting publication contains presentations and discussionsby prominent researchers engaged in this field. This book should stimulate further research on potential of brain tissue for recovery, and particularly with regard to a functional recovery of neurons suffering from chronic ischemic injury.
Author: K. Kogure
Publisher: Elsevier
ISBN: 0080862217
Category : Medical
Languages : en
Pages : 299
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Book Description
In the eight years since the publication of Volume 63 of Progress in Brain Research, on this subject, developments in the research field have been very fast. For example, receptor physiology and pharmacology is now an intensively studied field, and the excitotoxic hypothesis of cell death is commonly accepted. Furthermore, it is recognized that ischemia and other insults give rise to a sustained depression of overall protein synthesis, yet lead to the expression of dormant genes and to synthesis of new proteins.In view of this development, this volume focusses on the cellular and molecular aspects of ischemic brain damage. The book will be of great value to all those interested in the pathophysiology of ischemic and traumatic brain damage.
Author: Alexander Hartmann
Publisher: Springer Science & Business Media
ISBN: 3642858635
Category : Medical
Languages : en
Pages : 590
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Book Description
Although many books deal with isolated problems of calcium disturbance in relation to cardiac and cerebral function, this is the first to focus specifically on calcium metabolism and cerebral ischemia. Internationally acknowledged experts present recent data and new concepts in an interdisciplinary approach to the subject. They examine basic information on the pathophysiology of cellular events, the damage caused by excitotoxic substances, and the effects of calcium antagonistic drugs as measured in experimental animals. These contributions may help lead to possible therapeutic interference for the prevention of calcium imbalance.
