Pharmacology and Therapeutics in the New Millennium

Pharmacology and Therapeutics in the New Millennium PDF Author: S.K. Gupta
Publisher: Springer Science & Business Media
ISBN: 9780792370598
Category : Science
Languages : en
Pages : 772

Get Book Here

Book Description
During the past several years tremendous advancements have been made in the field of pharmacology and therapeutics. While new therapeutic strategies are coming up, old ones are being improved by modifications, or being replaced with newer ones. The major topics covered in this book include: endothelins, current topics in cardiovascular research, molecular pharmacology, recent developments in cancer research, antioxidants, oxidants and human disease, herbal drugs, developments in neuropharmacology, myelin biology and demyelinating disease, pharmacovigilance, role of cytokines in health and disease, ocular pharmacology, detoxification of xenobiotics-biotransformation and transport, and several other topics of current interest. The aim of this book is to fulfill the needs of the basic and clinical researchers as well as the students, particularly related to areas of current interest in pharmacology and therapeutics.

Pharmacology and Therapeutics in the New Millennium

Pharmacology and Therapeutics in the New Millennium PDF Author: S.K. Gupta
Publisher: Springer Science & Business Media
ISBN: 9780792370598
Category : Science
Languages : en
Pages : 772

Get Book Here

Book Description
During the past several years tremendous advancements have been made in the field of pharmacology and therapeutics. While new therapeutic strategies are coming up, old ones are being improved by modifications, or being replaced with newer ones. The major topics covered in this book include: endothelins, current topics in cardiovascular research, molecular pharmacology, recent developments in cancer research, antioxidants, oxidants and human disease, herbal drugs, developments in neuropharmacology, myelin biology and demyelinating disease, pharmacovigilance, role of cytokines in health and disease, ocular pharmacology, detoxification of xenobiotics-biotransformation and transport, and several other topics of current interest. The aim of this book is to fulfill the needs of the basic and clinical researchers as well as the students, particularly related to areas of current interest in pharmacology and therapeutics.

Discoveries in Pharmacological Sciences

Discoveries in Pharmacological Sciences PDF Author: Popat N. Patil
Publisher: World Scientific
ISBN: 9814355070
Category : Medical
Languages : en
Pages : 793

Get Book Here

Book Description
Throughout history, the perpetuation of species, the need for survival, and human curiosity, intelligence and skills provided the basis for the development of drug science. This unique book, Discoveries in Pharmacological Sciences, contains the history of herbal medicine as it emerged about 5,000 years ago. Recent discoveries in genetics are integrated with the observations in the past. An understanding of the history of drugs and toxic chemicals is essential for the proper utility of these substances by the population at large. The book is written with the purpose to familiarize drug research of the investigators in chemical, pharmaceutical, pharmacological, and biomedical sciences. It is important to note that plants containing morphine, quinine, physostigmine, pilocarpine, atropine, d-tubocurarine, reserpine, tetrahydrocannabinol, cardiac glycosides, ephedrine and colchicine were used by various cultures for centuries. Since 1805 pure, active, therapeutic constituents were isolated and chemically characterized. Parallel to these developments, the science of human anatomy, physiology, biochemistry, genetics and pharmacology has advanced. New synthetic drugs were discovered. The chemistry of perfumes and sensory functions including memory were elucidated. The history of fascinating discoveries made by scientists of Nobel repute is documented. Better testing methods were developed. The causes of many diseases were better understood. Drug laws were instituted a century ago. The pharmaceutical industry flourished. The text provides a panoramic view of the understanding of when, where, who, how and why drugs were developed. Educational aspects of teaching pharmacological sciences are reviewed. The historical account will be invaluable to graduate students and creative scientists, who can prepare for the future. The book will serve to enhance the cumulative scientific knowledge of the investigators in drug discovery. It contains a well integrated wealth of information in drug sciences and pharmacotherapeutics. The time, place and the human side of investigators, their portraits with biographical sketches are presented. The reading of Discoveries in Pharmacological Sciences will satisfy the intellectual curiosity of investigators. Understanding of Discoveries in Pharmacological Sciences will provide a platform to judge the importance of the personalized medicine of tomorrow. Scattered classical information about drug sciences is effectively condensed here. The development of the scientific thoughts and creativity of the investigators through the ages in drug research are presented admirably.

An Introduction to Mushroom

An Introduction to Mushroom PDF Author: Ajit Kumar Passari
Publisher: BoD – Books on Demand
ISBN: 1789859557
Category : Science
Languages : en
Pages : 150

Get Book Here

Book Description
The mushroom has a wide number of medicinal properties such as being an antioxidant, antimicrobial, anticancer, antidiabetic, immune enhancer, and also used for the treatment of various diseases such as anthelmintic, anti-inflammatory, antipyretics, etc. According to current information, there are approximately twelve-thousand species in the world, and out of them, 2000 species are reported as being edible. Around 35 edible mushroom varieties are cultivated commercially, whereas almost 200 wild species could be used for medicinal purposes. This book also covers the diversity of edible mushrooms and describes several applications as an alternative source for food production and clinical approach. This book includes: • the diverse types of mushroom and their enzymatic activity • importance of nutritional properties along with their food product development • industrial and clinical applications of macro fungi, i.e., degradation of dyes, anticancer, antimicrobial, antioxidant, etc.

Ayurveda in The New Millennium

Ayurveda in The New Millennium PDF Author: D. Suresh Kumar
Publisher: CRC Press
ISBN: 100020488X
Category : Health & Fitness
Languages : en
Pages : 301

Get Book Here

Book Description
Ayurveda or "the sacred knowledge of longevity" has been practiced in India and many Asian countries since time immemorial. Interest in Ayurveda started growing all over the world in the late 1970s, following the Alma Ata Declaration adopted by the W.H.O. in 1978. Ayurveda in the New Millennium: Emerging Roles and Future Challenges attempts to survey the progress made in this field and to formulate a course of action to take Ayurveda through the new millennium. It also identifies the many stumbling blocks that need to be removed if Ayurveda is to cater to the needs of a wider audience. Features: Newer insights into the history of Ayurveda Regulatory aspects of the manufacture of ayurvedic medicines Industrial production of traditional ayurvedic medicines Quality control The scientific rationale of single herb therapy Biological effects of ayurvedic formulations Optimization of ancient wisdom and newer knowledge Conservation of threatened herbs Nutraceuticals and cosmeceuticals from Ayurveda Critical view of Ayurveda in the West Direction for the Ayurveda renaissance Ayurveda in the New Millennium: Emerging Roles and Future Challenges describes the strength of Ayurveda and how to usher in the Ayurveda renaissance. This book will be of interest to proponents of Ayurveda and all branches of traditional and alternative medicine. Experts from the fields of medicine, pharmacology, new drug discovery and food technology will also find it useful.

Peptide-based Drug Discovery

Peptide-based Drug Discovery PDF Author: Ved Srivastava
Publisher: Royal Society of Chemistry
ISBN: 1782627324
Category : Medical
Languages : en
Pages : 589

Get Book Here

Book Description
With potentially high specificity and low toxicity, biologicals offer promising alternatives to small-molecule drugs. Peptide therapeutics have again become the focus of innovative drug development efforts backed up by a resurgence of venture funds and small biotechnology companies. What does it take to develop a peptide-based medicine? What are the key challenges and how are they overcome? What are emerging therapeutics for peptide modalities? This book answers these questions with a holistic story from molecules to medicine, combining the themes of design, synthesis and clinical applications of peptide-based therapeutics and biomarkers. Chapters are written and edited by leaders in the field from industry and academia and they cover the pharmacokinetics of peptide therapeutics, attributes necessary for commercially successful metabolic peptides, medicinal chemistry strategies for the design of peptidase-resistant peptide analogues, disease classes for which peptide therapeutic are most relevant, and regulatory issues and guidelines. The critical themes covered provide essential background information on what it takes to develop peptide-based medicine from a chemistry perspective and views on the future of peptide drugs. This book will be a valuable resource not only as a reference book for the researcher engaged in academic and pharmaceutical setting, from basic research to manufacturing and from organic chemistry to biotechnology, but also a valuable resource to graduate students to understand discovery and development process for peptide-based medicine.

Clinical Trials Handbook

Clinical Trials Handbook PDF Author: Shayne Cox Gad
Publisher: John Wiley & Sons
ISBN: 0470466359
Category : Science
Languages : en
Pages : 1247

Get Book Here

Book Description
Best practices for conducting effective and safe clinical trials Clinical trials are arguably the most important steps in proving drug effectiveness and safety for public use. They require intensive planning and organization and involve a wide range of disciplines: data management, biostatistics, pharmacology, toxicology, modeling and simulation, regulatory monitoring, ethics, and particular issues for given disease areas. Clinical Trials Handbook provides a comprehensive and thorough reference on the basics and practices of clinical trials. With contributions from a range of international authors, the book takes the reader through each trial phase, technique, and issue. Chapters cover every key aspect of preparing and conducting clinical trials, including: Interdisciplinary topics that have to be coordinated for a successful clinical trialData management (and adverse event reporting systems) Biostatistics, pharmacology, and toxicology Modeling and simulation Regulatory monitoring and ethics Particular issues for given disease areas-cardiology, oncology, cognitive, dementia, dermatology, neuroscience, and more With unique information on such current issues as adverse event reporting (AER) systems, adaptive trial designs, and crossover trial designs, Clinical Trials Handbook will be a ready reference for pharmaceutical scientists, statisticians, researchers, and the many other professionals involved in drug development.

Veterinary Pharmacology and Therapeutics

Veterinary Pharmacology and Therapeutics PDF Author: Jim E. Riviere
Publisher: John Wiley & Sons
ISBN: 0813820618
Category : Medical
Languages : en
Pages : 1541

Get Book Here

Book Description
'Veterinary Pharmacology and Therapeutics' has been thoroughly revised, updated and expanded to meet the needs of today's veterinarians, veterinary students, and animal health researchers.

Pharmacotherapeutics for Advanced Practice

Pharmacotherapeutics for Advanced Practice PDF Author: Virginia Poole Arcangelo
Publisher: Lippincott Williams & Wilkins
ISBN: 9780781757843
Category : Medical
Languages : en
Pages : 988

Get Book Here

Book Description
This advanced pharmacotherapeutics text for nurse practitioners and physician assistants offers guidelines on prescribing drugs for over 50 common diseases and disorders. The book is organized by disorder rather than drug class and includes algorithms and case studies that illustrate critical thinking aspects of prescribing, such as drug selection, lifespan considerations, therapeutic drug monitoring, adverse reactions, unexpected outcomes, and when to change therapy. This Second Edition has new chapters on oncologic disorders and complementary and alternative medicines. Improved case studies reflect more realistic practice issues in decision-making. Additional areas addressed include food-drug interactions, dietary considerations, and concerns regarding geriatric patients.

Breast Cancer

Breast Cancer PDF Author: Phuc Van Pham
Publisher: BoD – Books on Demand
ISBN: 9535129996
Category : Medical
Languages : en
Pages : 570

Get Book Here

Book Description
Breast Cancer - From Biology to Medicine thoroughly examines breast cancer from basic definitions, to cellular and molecular biology, to diagnosis and treatment. This book also has some additional focus on preclinical and clinical results in diagnosis and treatment of breast cancer. The book begins with introduction on epidemiology and pathophysiology of breast cancer in Section 1. In Section 2, the subsequent chapters introduce molecular and cellular biology of breast cancer with some particular signaling pathways, the gene expression, as well as the gene methylation and genomic imprinting, especially the existence of breast cancer stem cells. In Section 3, some new diagnostic methods and updated therapies from surgery, chemotherapy, hormone therapy, immunotherapy, radiotherapy, and some complementary therapies are discussed. This book provides a succinct yet comprehensive overview of breast cancer for advanced students, graduate students, and researchers as well as those working with breast cancer in a clinical setting.

Analytical Toxicology for Poisoning Management and Toxicovigilance

Analytical Toxicology for Poisoning Management and Toxicovigilance PDF Author: S. K. Gupta
Publisher: Alpha Science Int'l Ltd.
ISBN: 9788173194894
Category : Medical
Languages : en
Pages : 134

Get Book Here

Book Description
This volume covers services of the Toxicology Laboratory from common general emergency medicine to specialized treatment units, defining procedures for critical quantitative analysis in treating acute poisoning cases. If the diagnosis or the prognosis is in doubt, active elimination therapy is considered or the administration of certain antidotes is contemplated. Hence, the book describes not only simple analytical techniques such as various advanced techniques such as High performance liquid chromatography Gas chromatography Ultraviolet-visible spectrophotometry and Atomic absorption spectrometry Presently detailed account of Instrumentation Operating procedures Possible interfaces in the methodology and Prototype examples of analytical procedures specifying the sensitivity of each test.