Pharmacological targeting of tumor microenvironment: From bench to bedside, volume II

Pharmacological targeting of tumor microenvironment: From bench to bedside, volume II PDF Author: Chang Zou
Publisher: Frontiers Media SA
ISBN: 283252379X
Category : Medical
Languages : en
Pages : 241

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Book Description

Pharmacological targeting of tumor microenvironment: From bench to bedside, volume II

Pharmacological targeting of tumor microenvironment: From bench to bedside, volume II PDF Author: Chang Zou
Publisher: Frontiers Media SA
ISBN: 283252379X
Category : Medical
Languages : en
Pages : 241

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Book Description


Frontiers in Anti-Cancer Drug Discovery

Frontiers in Anti-Cancer Drug Discovery PDF Author: Atta-ur Rahman
Publisher: Bentham Science Publishers
ISBN: 1681083892
Category : Medical
Languages : en
Pages : 181

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Book Description
Frontiers in Anti-Cancer Drug Discovery is a book series devoted to publishing the latest and the most important advances in anti-cancer drug design and discovery. Eminent scientists write contributions on all areas of rational drug design and drug discovery including medicinal chemistry, in-silico drug design, combinatorial chemistry, high-throughput screening, drug targets, recent important patents, and structure-activity relationships. The book series should prove to be of interest to all pharmaceutical scientists involved in research in anti-cancer drug design and discovery. Each volume is devoted to the major advances in anti-cancer drug design and discovery. The book series is essential reading to all scientists involved in drug design and discovery who wish to keep abreast of rapid and important developments in the field. The eighth volume of the series features chapters covering the following topics: - T cells in gastrointestinal cancers - The pharmacology of adjudin – a male contraceptive with anti-cancer properties - Manipulating the tumor microenvironment - Treatment of hepatocellular carcinoma - Gold-based compounds as potential anti-cancer drug candidates - Oral nanostructure drug delivery for anti-cancer treatment

Bio-Nanomedicine for Cancer Therapy

Bio-Nanomedicine for Cancer Therapy PDF Author: Flavia Fontana
Publisher: Springer Nature
ISBN: 3030581748
Category : Medical
Languages : en
Pages : 358

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Book Description
The book covers the latest developments in biologically-inspired and derived nanomedicine for cancer therapy. The purpose of the book is to illustrate the significance of naturally-mimicking systems for enhancing the dose delivered to the tumor, to improve stability, and prolong the circulation time. Moreover, readers are presented with advanced materials such as adjuvants for immunostimulation in cancer vaccines. The book also provides a comprehensive overview of the current status of academic research. This is an ideal book for students, researchers, and professors working in nanotechnology, cancer, targeted drug delivery, controlled drug release, materials science, and biomaterials as well as companies developing cancer immunotherapy.

Targeting Signaling Pathways in Solid Tumors Part C

Targeting Signaling Pathways in Solid Tumors Part C PDF Author:
Publisher: Elsevier
ISBN: 0443235511
Category : Science
Languages : en
Pages : 357

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Book Description
Targeting Signaling Pathways in Solid Tumors, Part C, Volume 389 in the International Review of Cell and Molecular Biology series, highlights new advances in the field, with this new volume presenting interesting chapters on topics such as Drugging the Undruggable: Advances in Targeting KRAS Signaling in Solid Tumors, Emerging Trends in Gastrointestinal Cancers: Targeting Developmental Pathways in their Carcinogenesis and Tumor Progression, Importance of targeting various cell signaling pathways in solid cancers, Targeting signaling pathways in cancer stem cells: a potential approach for developing novel anticancer therapeutics, Factors affecting heterogeneity in breast cancer microenvironment: A narrative review, and much more.Additional sections cover Exploring TLR Signaling Pathways as Promising Targets in Cervical Cancer: The Road Less Travelled - Provides the latest information on cancer research - Offers outstanding and original reviews on a range of cancer research topics - Serves as an indispensable reference for researchers and students alike

Biomedical Chemistry

Biomedical Chemistry PDF Author: Nuno Vale
Publisher: Walter de Gruyter GmbH & Co KG
ISBN: 3110468751
Category : Science
Languages : en
Pages : 361

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Book Description
Biomedical Chemistry provides readers with an understanding of how fundamental chemical concepts are used to combat some diseases. The authors explain the interdisciplinary relationship of chemistry with biology, physics, pharmacy and medicine. The results of chemical research can be applied to understand chemical processes in cells and in the body, and new methods for drug transportation. Also, basic chemical ideas and determination of disease etiology are approached by developing techniques to ensure optimum interaction between drugs and human cells. This Book is an excellent resource for students and researchers in health-related fields with frontier topics in medicinal and pharmaceutical chemistry, organic chemistry and biochemistry.

Cancer Nanotheranostics

Cancer Nanotheranostics PDF Author: Muthupandian Saravanan
Publisher: Springer Nature
ISBN: 3030762637
Category : Medical
Languages : en
Pages : 379

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Book Description
Cancer Nanotheranostics, Volume 2 continues the discussion of the important work being done in this field of cancer nanotechnology. The contents of these two volumes are explained in detail as follows. In the first volume of Cancer Nanotheranostics, we discuss the role of different nanomaterials for cancer therapy including lipid-based nanomaterials, protein and peptide-based nanomaterials, polymer-based nanomaterials, metal-organic nanomaterials, porphyrin-based nanomaterials, metal-based nanomaterials, silica-based nanomaterials, exosome-based nanomaterials, and nano-antibodies. This important second volume discusses nano-based diagnosis of cancer, nano-oncology for clinical applications, nano-immunotherapy, nano-based photothermal cancer therapy, nanoerythrosomes for cancer drug delivery, regulatory perspectives of nanomaterials, limitations of cancer nanotheranostics, safety of nanobiomaterials for cancer nanotheranostics, multifunctional nanomaterials for targeting cancer nanotheranostics, and the role of artificial intelligence in cancer nanotheranostics. Volume 2 is a vital continuation of this two-volume set. Together, these two volumes create a comprehensive and unique examination of this important area of research.

Photophysics and Nanophysics in Therapeutics

Photophysics and Nanophysics in Therapeutics PDF Author: Nilesh M. Mahajan
Publisher: Elsevier
ISBN: 0323885683
Category : Medical
Languages : en
Pages : 478

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Book Description
Photophysics and Nanophysics in Therapeutics explores the latest advances and applications of phototherapy and nanotherapy, covering the application of light, radiation, and nanotechnology in therapeutics, along with the fundamental principles of physics in these areas. Consisting of two parts, the book first features a range of chapters covering phototherapeutics, from the fundamentals of photodynamic therapy (PDT) to applications such as cancer treatment and advances in radiotherapy, applied physics in cancer radiotherapy treatment, and the role of carbon ion beam therapy. Other sections cover nanotherapeutics, potential applications and challenges, and nanotherapy for drug delivery to the brain. Final chapters delve into nanotechnology in the diagnosis and treatment of cancers, the role of nanocarriers for HIV treatment, nanoparticles for rheumatoid arthritis treatment, peptide functionalized nanomaterials as microbial sensors, and theranostic nanoagents. - Evaluates the latest developments in the fields of phototherapy and nanotherapy - Investigates the fundamental physics behind these technologies - Explores therapeutic applications across a range of diseases, such as skin disorders, cancer, and neurological conditions - Includes case studies that illustrate research in practice - Considers challenges and future perspectives

Nanocarriers for Drug-Targeting Brain Tumors

Nanocarriers for Drug-Targeting Brain Tumors PDF Author: Lalit Kumar
Publisher: Elsevier
ISBN: 0323914713
Category : Technology & Engineering
Languages : en
Pages : 864

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Book Description
Nanocarriers for Drug-Targeting Brain Tumors covers different types of nanocarriers and their design and development for targeting drugs to the brain. The book also presents case studies and the mechanism of action of nanocarriers in drug targeting to a specific site. This helps researchers and clinicians understand the design, development and mechanism of action of nanocarriers. As brain tumors continue to be a significant health problem globally, and very complex for targeting drugs, conventional dosage forms are not very effective and side-effects are a major concern. Functionalized nanocarriers can address these problems. Furthermore, the targeting of nanocarriers is preferred for reducing toxicity and improving the effectiveness of the drugs. However, there is a need for understanding the design and development of formulation with the mechanism of action of nanocarriers for brain targeting. - Provides information on the design and development of nanocarriers for targeting brain tumors - Outlines the working principles of different nanocarriers for targeting brain tumors - Includes case studies of different nanocarriers for targeting brain tumors

Innovative Pharmacometric Approaches to Inform Drug Development and Clinical Use

Innovative Pharmacometric Approaches to Inform Drug Development and Clinical Use PDF Author: Zinnia P. Parra-Guillen
Publisher: Frontiers Media SA
ISBN: 2832545033
Category : Science
Languages : en
Pages : 117

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Book Description
Pharmacometrics represents a strategy to optimize and rationalize decision-making process integrating information on drug behavior, pharmacological response, and disease progression both in the drug development phases and in their clinical use. Pharmacometrics focuses on characterizing the pharmacokinetic and pharmacodynamic behavior of one or several active ingredients through the development of mathematical and statistical models that allow characterizing both the average behavior in the population and the different sources of variability. Currently, pharmacometrics has transformed drug development and therapeutic use paradigm, which yield to the recognition by the main regulatory agencies (FDA, EMA, and PMDA).

The Elusive Road Towards Effective Cancer Prevention and Treatment

The Elusive Road Towards Effective Cancer Prevention and Treatment PDF Author: Franklyn De Silva
Publisher: CRC Press
ISBN: 1000738957
Category : Medical
Languages : en
Pages : 231

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Book Description
Cancer will remain a global major health problem unless new diagnostic, prognostic, and management approaches are discovered to address both loss of life and quality of life. Here we summarize the general physiology, pathology, heterogeneity, and evolution of cancer, current status, limitations and challenges associated with prevention, incidence, treatment, survival, and mortality, as well as future directions with regards to solid tumors. Perspectives are provided on how to improve pre-clinical understandings, outcomes, and patient care. Further, this comprehensive, timely overview of the literature has educational value as part of an academic course, seminar, or as a supplementary text.