Personalized Medicine and Neurosurgery

Personalized Medicine and Neurosurgery PDF Author: M. Yashar S. Kalani
Publisher: Frontiers Media SA
ISBN: 2889453367
Category :
Languages : en
Pages : 135

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Book Description
The Precision Medicine Initiative, which was instituted by President Barack Obama on January 20, 2015, highlighted the importance that advances in genomics and related “-omic” approaches have made to science and medicine, and it set the stage for their federally funded and mandated integration into the delivery of health care. Whether these advances comprise large-scale approaches, such as The Cancer Genome Atlas, which provides a modern classification of cancers based on molecular profiles, or genealogy initiatives, which seek to trace the movement of our early ancestors out of Africa, genomic technology has taken us closer to developing targeted therapies and a refined understanding of our evolutionary journey. It is against this backdrop that we summarized some of the recent advances in the field of precision medicine, or personalized medicine, as they pertain to neurosurgery. In this e-Book collection provided by Frontiers in Surgery: Neurosurgery, we present a collection of articles by leaders in the field of neurosurgery that highlight domains using a personalized approach for the treatment of patients or avenues when personalization is possible and when it will likely alter the care of patients with neurological diseases.

Personalized Medicine and Neurosurgery

Personalized Medicine and Neurosurgery PDF Author: M. Yashar S. Kalani
Publisher: Frontiers Media SA
ISBN: 2889453367
Category :
Languages : en
Pages : 135

Get Book Here

Book Description
The Precision Medicine Initiative, which was instituted by President Barack Obama on January 20, 2015, highlighted the importance that advances in genomics and related “-omic” approaches have made to science and medicine, and it set the stage for their federally funded and mandated integration into the delivery of health care. Whether these advances comprise large-scale approaches, such as The Cancer Genome Atlas, which provides a modern classification of cancers based on molecular profiles, or genealogy initiatives, which seek to trace the movement of our early ancestors out of Africa, genomic technology has taken us closer to developing targeted therapies and a refined understanding of our evolutionary journey. It is against this backdrop that we summarized some of the recent advances in the field of precision medicine, or personalized medicine, as they pertain to neurosurgery. In this e-Book collection provided by Frontiers in Surgery: Neurosurgery, we present a collection of articles by leaders in the field of neurosurgery that highlight domains using a personalized approach for the treatment of patients or avenues when personalization is possible and when it will likely alter the care of patients with neurological diseases.

Becoming Dr. Q

Becoming Dr. Q PDF Author: Alfredo Quiñones-Hinojosa
Publisher: Univ of California Press
ISBN: 0520949609
Category : Social Science
Languages : en
Pages : 328

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Book Description
Today he is known as Dr. Q, an internationally renowned neurosurgeon and neuroscientist who leads cutting-edge research to cure brain cancer. But not too long ago, he was Freddy, a nineteen-year-old undocumented migrant worker toiling in the tomato fields of central California. In this gripping memoir, Alfredo Quiñones-Hinojosa tells his amazing life story—from his impoverished childhood in the tiny village of Palaco, Mexico, to his harrowing border crossing and his transformation from illegal immigrant to American citizen and gifted student at the University of California at Berkeley and at Harvard Medical School. Packed with adventure and adversity—including a few terrifying brushes with death—Becoming Dr. Q is a testament to persistence, hard work, the power of hope and imagination, and the pursuit of excellence. It’s also a story about the importance of family, of mentors, and of giving people a chance.

Neurosurgery

Neurosurgery PDF Author: Christianto B. Lumenta
Publisher: Springer Science & Business Media
ISBN: 3540795650
Category : Medical
Languages : en
Pages : 651

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Book Description
In a specialized field such as neurosurgery, highly specific knowledge is required. Training programs in the EU vary, making it difficult to standardize medical training. This manual forms the basis for a European consensus in neurosurgery. It is written for residents, students and physicians with a special interest in neurosurgery. Diagnostic and therapeutic procedures are detailed according to localization (cranial, spinal, peripheral nerves) with special consideration given to congenital defects and pediatric neurosurgical disorders, functional and stereotactic neurosurgery, as well as critical neurosurgical care. Each chapter contains the basics of anatomy and physiology. The book is well-organized and clearly structured according to each entity and its neurosurgical treatment options. A better understanding of specific neurosurgical problems will help practicing neurosurgeons provide better medical care for their patients, and will also provide the neurosurgery resident with a reliable European standard for step-by-step management of neurosurgical problems, which will prove useful when preparing for the board examination.

Toward Precision Medicine

Toward Precision Medicine PDF Author: National Research Council
Publisher: National Academies Press
ISBN: 0309222222
Category : Medical
Languages : en
Pages : 142

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Book Description
Motivated by the explosion of molecular data on humans-particularly data associated with individual patients-and the sense that there are large, as-yet-untapped opportunities to use this data to improve health outcomes, Toward Precision Medicine explores the feasibility and need for "a new taxonomy of human disease based on molecular biology" and develops a potential framework for creating one. The book says that a new data network that integrates emerging research on the molecular makeup of diseases with clinical data on individual patients could drive the development of a more accurate classification of diseases and ultimately enhance diagnosis and treatment. The "new taxonomy" that emerges would define diseases by their underlying molecular causes and other factors in addition to their traditional physical signs and symptoms. The book adds that the new data network could also improve biomedical research by enabling scientists to access patients' information during treatment while still protecting their rights. This would allow the marriage of molecular research and clinical data at the point of care, as opposed to research information continuing to reside primarily in academia. Toward Precision Medicine notes that moving toward individualized medicine requires that researchers and health care providers have access to very large sets of health- and disease-related data linked to individual patients. These data are also critical for developing the information commons, the knowledge network of disease, and ultimately the new taxonomy.

Personalized Medicine and Neurosurgery

Personalized Medicine and Neurosurgery PDF Author:
Publisher:
ISBN:
Category :
Languages : en
Pages : 0

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Book Description
The Precision Medicine Initiative, which was instituted by President Barack Obama on January 20, 2015, highlighted the importance that advances in genomics and related "-omic" approaches have made to science and medicine, and it set the stage for their federally funded and mandated integration into the delivery of health care. Whether these advances comprise large-scale approaches, such as The Cancer Genome Atlas, which provides a modern classification of cancers based on molecular profiles, or genealogy initiatives, which seek to trace the movement of our early ancestors out of Africa, genomic technology has taken us closer to developing targeted therapies and a refined understanding of our evolutionary journey. It is against this backdrop that we summarized some of the recent advances in the field of precision medicine, or personalized medicine, as they pertain to neurosurgery. In this e-Book collection provided by Frontiers in Surgery: Neurosurgery, we present a collection of articles by leaders in the field of neurosurgery that highlight domains using a personalized approach for the treatment of patients or avenues when personalization is possible and when it will likely alter the care of patients with neurological diseases.

Neurosurgery Self-Assessment E-Book

Neurosurgery Self-Assessment E-Book PDF Author: Rahul S. Shah
Publisher: Elsevier Health Sciences
ISBN: 0323392326
Category : Medical
Languages : en
Pages : 888

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Book Description
Ideal for both neurosurgical residents and recertifying neurosurgeons, Neurosurgery Self-Assessment: Questions and Answers offers the most comprehensive, up to date coverage available. Over 1,000 clinically relevant multiple-choice questions across 46 topic areas test the candidate's knowledge of basic neuroscience and neurosurgical subspecialties to an unparalleled degree and provide detailed answer explanations to facilitate learning and assessment. - Over 700 histology, pathology, radiology, clinical and anatomical images serve as an index of routinely tested-on images in neurosurgical examinations with high-yield summaries of each pathology to reinforce and simplify key concepts. - Includes only multiple choice questions in both single-best-answer and extended matching item (10-20 options) format increasingly adopted by neurosurgery certification boards worldwide. - Questions are organized by topic and classified by degree of difficulty through a highly visual "traffic light system" which codes each question in green, amber, or red. - Includes coverage of the landmark studies in areas such as vascular, stroke, spine and neurooncology. - Practical tips facilitate study with test-taking strategies and things to consider before sitting for an exam. - Utilizes Imperial and SI units throughout.

Connectomic Deep Brain Stimulation

Connectomic Deep Brain Stimulation PDF Author: Andreas Horn
Publisher: Academic Press
ISBN: 0128218622
Category : Medical
Languages : en
Pages : 602

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Book Description
Connectomic Deep Brain Stimulation (DBS) covers this highly efficacious treatment option for movement disorders such as Parkinson's Disease, Essential Tremor and Dystonia. The book examines its impact on distributed brain networks that span across the human brain in parallel with modern-day neuroimaging concepts and the connectomics of the brain. It asks several questions, including which cortical areas should DBS electrodes be connected in order to generate the highest possible clinical improvement? Which connections should be avoided? Could these connectomic insights be used to better understand the mechanism of action of DBS? How can they be transferred to individual patients, and more. This book is suitable for neuroscientists, neurologists and functional surgeons studying DBS. It provides practical advice on processing strategies and theoretical background, highlighting and reviewing the current state-of-the-art in connectomic surgery. - Written to provide a "hands-on" approach for neuroscience graduate students, as well as medical personnel from the fields of neurology and neurosurgery - Includes preprocessing strategies (such as co-registration, normalization, lead localization, VTA estimation and fiber-tracking approaches) - Presents references (key articles, books and protocols) for additional detailed study - Provides data analysis boxes in each chapter to help with data interpretation

Textbook of Personalized Medicine

Textbook of Personalized Medicine PDF Author: Kewal K. Jain
Publisher: Humana Press
ISBN: 1493925539
Category : Medical
Languages : en
Pages : 762

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Book Description
Advances in the technology used in personalized medicine and increased applications for clinical use have created a need for this expansion and revision of Kewal K. Jain’s Textbook of Personalized Medicine. As the first definitive work on this topic, this book reviews the fundamentals and development of personalized medicine and subsequent adoptions of the concepts by the biopharmaceutical industry and the medical profession. It also discusses examples of applications in key therapeutic areas, as well as ethical and regulatory issues, providing a concise and comprehensive source of reference for those involved in healthcare management, planning and politics. Algorithms are included as a guide to those involved in the management of important diseases where decision-making is involved due to the multiple choices available. Textbook of Personalized Medicine, Second Edition will serve as a convenient source of information for physicians, scientists, decision makers in the biopharmaceutical and healthcare industries and interested members of the public.

A History of Neurosurgery

A History of Neurosurgery PDF Author: Samuel H. Greenblatt
Publisher: Thieme
ISBN: 9781879284173
Category : Medical
Languages : en
Pages : 648

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Book Description
A History of Neurosurgery is the first thorough book on the history of neurosurgery published since 1951. The book is organized around a specific historiographic framework that traces the advancement of the specialty. Included are chapters on ancient trepanation, Macewen's first use of the combined technologies of anesthesia, antisepsis and cortical localization in 1879 to plan and perform craniotomies, the emergence of Harvey Cushing's leadership, the evolution of modern neurosurgical techniques and technology and much more.

Surviving Neurosurgery

Surviving Neurosurgery PDF Author: Nitin Agarwal
Publisher: Springer
ISBN: 9783030869168
Category : Medical
Languages : en
Pages : 555

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Book Description
Surviving Neurosurgery: Vignettes of Resilience is a practical guide to the inner workings of the lives of neurosurgeons, healthcare partners, and patients. To this end, this text serves as a first-hand documentary of the unique challenges faced as one progresses through their career. It is a snapshot in time capturing the experiences of both patients and providers. The text is divided into seven parts that run the gamut of a neurosurgeon’s career symbolic of the seven years of neurosurgical training. These narratives include, but are not limited to, residency challenges, surgical nuances, research and funding, embracing humanity, patient experiences, and overcoming hurdles along the journey. Chapters share the wisdom and experiences of over 100 authors consisting of patients, trainees, advanced practice providers, and attending neurosurgeons.