Personalized, Evolutionary, and Ecological Dermatology

Personalized, Evolutionary, and Ecological Dermatology PDF Author: Robert A. Norman
Publisher: Springer
ISBN: 3319410881
Category : Medical
Languages : en
Pages : 152

Get Book Here

Book Description
This book discusses the exciting potential for dermatology to embrace developments to enhance the profession’s valuable pattern recognition, diagnostic, and treatment skills. Personalized medicine (PM) and genomics are easily accessible and enable the customization of healthcare using molecular analysis to influence medical decisions, practices, and therapies for the individual patient. The evolution of the skin, and the manner in which dermatological conditions are described and managed, reveals the need to consider many aspects on a personal level. New research data are based on the use of evolutionary medicine and genomics to highlight how we can become more successful at finding the most efficacious types of antibiotic or therapy and dosage for a particular disease or pathogen and build a competitive edge by prevention and risk management against invasive viruses, bacteria, or wrongly administered drugs. As more is understood about what grows on us and how it all interacts, along with how the introduction of new antibiotics, biologics, and other therapies affect our skin’s ecological balance, this book aims to create a heightened sense of the importance and offerings of ecological dermatology.

Personalized, Evolutionary, and Ecological Dermatology

Personalized, Evolutionary, and Ecological Dermatology PDF Author: Robert A. Norman
Publisher: Springer
ISBN: 3319410881
Category : Medical
Languages : en
Pages : 152

Get Book Here

Book Description
This book discusses the exciting potential for dermatology to embrace developments to enhance the profession’s valuable pattern recognition, diagnostic, and treatment skills. Personalized medicine (PM) and genomics are easily accessible and enable the customization of healthcare using molecular analysis to influence medical decisions, practices, and therapies for the individual patient. The evolution of the skin, and the manner in which dermatological conditions are described and managed, reveals the need to consider many aspects on a personal level. New research data are based on the use of evolutionary medicine and genomics to highlight how we can become more successful at finding the most efficacious types of antibiotic or therapy and dosage for a particular disease or pathogen and build a competitive edge by prevention and risk management against invasive viruses, bacteria, or wrongly administered drugs. As more is understood about what grows on us and how it all interacts, along with how the introduction of new antibiotics, biologics, and other therapies affect our skin’s ecological balance, this book aims to create a heightened sense of the importance and offerings of ecological dermatology.

Clean

Clean PDF Author: James Hamblin
Publisher: Penguin
ISBN: 0525538313
Category : Health & Fitness
Languages : en
Pages : 290

Get Book Here

Book Description
Named a Best Book of 2020 by NPR and Vanity Fair One of Smithsonian's Ten Best Science Books of 2020 “A searching and vital explication of germ theory, social norms, and what the modern era is really doing to our bodies and our psyches.” —Vanity Fair A preventative medicine physician and staff writer for The Atlantic explains the surprising and unintended effects of our hygiene practices in this informative and entertaining introduction to the new science of skin microbes and probiotics. Keeping skin healthy is a booming industry, and yet it seems like almost no one agrees on what actually works. Confusing messages from health authorities and ineffective treatments have left many people desperate for reliable solutions. An enormous alternative industry is filling the void, selling products that are often of questionable safety and totally unknown effectiveness. In Clean, doctor and journalist James Hamblin explores how we got here, examining the science and culture of how we care for our skin today. He talks to dermatologists, microbiologists, allergists, immunologists, aestheticians, bar-soap enthusiasts, venture capitalists, Amish people, theologians, and straight-up scam artists, trying to figure out what it really means to be clean. He even experiments with giving up showers entirely, and discovers that he is not alone. Along the way, he realizes that most of our standards of cleanliness are less related to health than most people think. A major part of the picture has been missing: a little-known ecosystem known as the skin microbiome—the trillions of microbes that live on our skin and in our pores. These microbes are not dangerous; they’re more like an outer layer of skin that no one knew we had, and they influence everything from acne, eczema, and dry skin, to how we smell. The new goal of skin care will be to cultivate a healthy biome—and to embrace the meaning of “clean” in the natural sense. This can mean doing much less, saving time, money, energy, water, and plastic bottles in the process. Lucid, accessible, and deeply researched, Clean explores the ongoing, radical change in the way we think about our skin, introducing readers to the emerging science that will be at the forefront of health and wellness conversations in coming years.

Gory Details

Gory Details PDF Author: Erika Engelhaupt
Publisher: National Geographic
ISBN: 1426220979
Category : Science
Languages : en
Pages : 340

Get Book Here

Book Description
"Erika Engelhaupt, founding editor of National Geographic's Gory Details blog, explores oft-ignored but alluring facets of biology, anatomy, space exploration, nature, and more. Featuring reporting and interviews with leading researchers in the field, Gory Details illuminates the world's most intriguing real-world applications of science"--

PSYCHOLOGICAL SUPPORT BY COGNITIVE BEHAVIORAL THERAPY FOR ATAXIA TELANGIECTASIA

PSYCHOLOGICAL SUPPORT BY COGNITIVE BEHAVIORAL THERAPY FOR ATAXIA TELANGIECTASIA PDF Author: Edenilson Brandl
Publisher: Edenilson Brandl
ISBN:
Category : Psychology
Languages : en
Pages : 1476

Get Book Here

Book Description
Ataxia Telangiectasia (A-T) is a rare, progressive genetic disorder that affects numerous systems in the body, most notably the neurological and immune systems. The profound impact of this condition extends beyond physical health, presenting significant psychological challenges that often remain inadequately addressed. Individuals with A-T and their families face not only the complexities of managing physical symptoms but also the emotional and mental toll associated with living with a degenerative disease. As a mental health professional, I have observed how critical it is for those with chronic conditions like Ataxia Telangiectasia to receive psychological support that is tailored to their specific needs. Cognitive Behavioral Therapy (CBT) has emerged as one of the most effective tools in providing this support, helping individuals manage emotional distress, develop coping strategies, and improve their overall quality of life. However, CBT for individuals with genetic and degenerative conditions requires unique considerations that go beyond standard therapeutic models. This book aims to bridge the gap between the physical and psychological aspects of Ataxia Telangiectasia by providing a comprehensive guide to the use of CBT in supporting individuals with A-T. It explores not only the biological foundations of the disorder but also delves deeply into the cognitive and emotional challenges it presents. Psychological Support by Cognitive Behavioral Therapy for Ataxia Telangiectasia is designed for mental health professionals, caregivers, and those personally affected by A-T. By integrating the latest findings in genetics, behavioral science, and therapeutic techniques, this book offers a multi-faceted approach to psychological care, focusing on practical tools that can be implemented in daily life. As you read through these pages, my hope is that you will gain not only a deeper understanding of Ataxia Telangiectasia but also feel equipped to support the mental well-being of those navigating this challenging journey. Through personalized therapy and resilience-building strategies, we can offer a more holistic approach to care—one that addresses both the mind and body. This book is written with the belief that individuals with A-T, like all of us, deserve the best support possible for their mental health, empowering them to lead fulfilling lives despite the challenges they face.

Precision Medicine and Artificial Intelligence

Precision Medicine and Artificial Intelligence PDF Author: Michael Mahler
Publisher: Academic Press
ISBN: 032385432X
Category : Science
Languages : en
Pages : 302

Get Book Here

Book Description
Precision Medicine and Artificial Intelligence: The Perfect Fit for Autoimmunity covers background on artificial intelligence (AI), its link to precision medicine (PM), and examples of AI in healthcare, especially autoimmunity. The book highlights future perspectives and potential directions as AI has gained significant attention during the past decade. Autoimmune diseases are complex and heterogeneous conditions, but exciting new developments and implementation tactics surrounding automated systems have enabled the generation of large datasets, making autoimmunity an ideal target for AI and precision medicine. More and more diagnostic products utilize AI, which is also starting to be supported by regulatory agencies such as the Food and Drug Administration (FDA). Knowledge generation by leveraging large datasets including demographic, environmental, clinical and biomarker data has the potential to not only impact the diagnosis of patients, but also disease prediction, prognosis and treatment options. - Allows the readers to gain an overview on precision medicine for autoimmune diseases leveraging AI solutions - Provides background, milestone and examples of precision medicine - Outlines the paradigm shift towards precision medicine driven by value-based systems - Discusses future applications of precision medicine research using AI - Other aspects covered in the book include regulatory insights, data analytics and visualization, types of biomarkers as well as the role of the patient in precision medicine

Phage Therapy: Past, Present and Future

Phage Therapy: Past, Present and Future PDF Author: Stephen T. Abedon
Publisher: Frontiers Media SA
ISBN: 2889452514
Category :
Languages : en
Pages : 394

Get Book Here

Book Description
Historically, the first observation of a transmissible lytic agent that is specifically active against a bacterium (Bacillus anthracis) was by a Russian microbiologist Nikolay Gamaleya in 1898. At that time, however, it was too early to make a connection to another discovery made by Dmitri Ivanovsky in 1892 and Martinus Beijerinck in 1898 on a non-bacterial pathogen infecting tobacco plants. Thus the viral world was discovered in two of the three domains of life, and our current understanding is that viruses represent the most abundant biological entities on the planet. The potential of bacteriophages for infection treatment have been recognized after the discoveries by Frederick Twort and Felix d’Hérelle in 1915 and 1917. Subsequent phage therapy developments, however, have been overshadowed by the remarkable success of antibiotics in infection control and treatment, and phage therapy research and development persisted mostly in the former Soviet Union countries, Russia and Georgia, as well as in France and Poland. The dramatic rise of antibiotic resistance and especially of multi-drug resistance among human and animal bacterial pathogens, however, challenged the position of antibiotics as a single most important pillar for infection control and treatment. Thus there is a renewed interest in phage therapy as a possible additive/alternative therapy, especially for the infections that resist routine antibiotic treatment. The basis for the revival of phage therapy is affected by a number of issues that need to be resolved before it can enter the arena, which is traditionally reserved for antibiotics. Probably the most important is the regulatory issue: How should phage therapy be regulated? Similarly to drugs? Then the co-evolving nature of phage-bacterial host relationship will be a major hurdle for the production of consistent phage formulae. Or should we resort to the phage products such as lysins and the corresponding engineered versions in order to have accurate and consistent delivery doses? We still have very limited knowledge about the pharmacodynamics of phage therapy. More data, obtained in animal models, are necessary to evaluate the phage therapy efficiency compared, for example, to antibiotics. Another aspect is the safety of phage therapy. How do phages interact with the immune system and to what costs, or benefits? What are the risks, in the course of phage therapy, of transduction of undesirable properties such as virulence or antibiotic resistance genes? How frequent is the development of bacterial host resistance during phage therapy? Understanding these and many other aspects of phage therapy, basic and applied, is the main subject of this Topic.

Global Public Health

Global Public Health PDF Author: Franklin White
Publisher: Oxford University Press
ISBN: 0199876991
Category : Medical
Languages : en
Pages : 378

Get Book Here

Book Description
Amid ongoing shifts in the world economic and political order, the promise for future public health is tenuous. Will today's economic systems sustain tomorrow's health? Will future generations inherit fair access to health and health care? An important hope for the health of future generations is the establishment of a well-grounded, global public health system. Global Public Health: Ecological Foundations addresses both the challenges and cooperative solutions of contemporary public health, within a framework of social justice, environmental sustainability, and global cooperation. With an emphasis on ecological foundations, this book approaches public health principles-history, foundations, topics, and applications-with a community-oriented perspective. By achieving global reach through cooperative, community-based interventions, this text illustrates that the practical application of public health principles can help maintain the health of the world's people. Blending established wisdom with new perspectives, Global Public Health will stimulate better understanding of how the different streams of public health can work more synergistically to promote global health equity. It is a foundation for future public health measures to be built and to succeed.

Patient Care Under Uncertainty

Patient Care Under Uncertainty PDF Author: Charles F. Manski
Publisher: Princeton University Press
ISBN: 0691194734
Category : Business & Economics
Languages : en
Pages : 184

Get Book Here

Book Description
For the past few years, the author, a renowned economist, has been applying the statistical tools of economics to decision making under uncertainty in the context of patient health status and response to treatment. He shows how statistical imprecision and identification problems affect empirical research in the patient-care sphere.

Mathematical Contributions to the Theory of Evolution

Mathematical Contributions to the Theory of Evolution PDF Author: Karl Pearson
Publisher:
ISBN:
Category : Biometry
Languages : en
Pages : 230

Get Book Here

Book Description


Atlas of Geriatric Dermatology

Atlas of Geriatric Dermatology PDF Author: Robert A. Norman
Publisher: Springer Science & Business Media
ISBN: 1447145798
Category : Medical
Languages : en
Pages : 334

Get Book Here

Book Description
This is a comprehensive, practical, densely illustrated diagnostic and therapeutic guide for all geriatric dermatology providers. The book comprises 50 chapters and over 600 color photographs on topics ranging from common conditions such as basal cell carcinoma, rosacea, and seborrheic dermatitis to unusual conditions such as angiosarcoma, dermatofibrosarcoma protuberans, and porphyria cutanea tarda. Sections include: - Inflammatory conditions (including contact dermatitis, alopecia, erythema multiforme, pemphigus, bullous pemphigoid, porphyria, pruritus, psoriasis, rosacea, seborrhea, urticaria, xerosis, and more) - Infections (fungus, herpes simplex and zoster, scabies, lice, and warts) - Skin signs in systemic disease (skin tags, cutaneous metastases, xanthomas) - Regional dermatoses (intertrigo, leg ulcers, pressure sores) - Benign tumors (chondrodermatitis, cysts, ganglion, fibrous papule, seborrheic keratoses, lentigines, and benign vascular lesions) - Pre-malignant and malignant tumors (actinic keratoses, angiosarcoma, basal cell carcinoma, dermatofibroma and dermatofibrosarcoma protuberans, intraepidermal neoplasia, Kaposi's sarcoma, keratoacanthoma, lentigo maligna, cutaneous lymphoma, Mycosis fiungoides, melanoma, nevi and moles, and squamous cell carcinoma)