Author: Mark D. LeBlanc
Publisher: Oxford University Press, USA
ISBN:
Category : Computers
Languages : en
Pages : 296

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Book Description
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Author: James Tisdall
Publisher: "O'Reilly Media, Inc."
ISBN: 0596550472
Category : Computers
Languages : en
Pages : 388

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Book Description
With its highly developed capacity to detect patterns in data, Perl has become one of the most popular languages for biological data analysis. But if you're a biologist with little or no programming experience, starting out in Perl can be a challenge. Many biologists have a difficult time learning how to apply the language to bioinformatics. The most popular Perl programming books are often too theoretical and too focused on computer science for a non-programming biologist who needs to solve very specific problems.Beginning Perl for Bioinformatics is designed to get you quickly over the Perl language barrier by approaching programming as an important new laboratory skill, revealing Perl programs and techniques that are immediately useful in the lab. Each chapter focuses on solving a particular bioinformatics problem or class of problems, starting with the simplest and increasing in complexity as the book progresses. Each chapter includes programming exercises and teaches bioinformatics by showing and modifying programs that deal with various kinds of practical biological problems. By the end of the book you'll have a solid understanding of Perl basics, a collection of programs for such tasks as parsing BLAST and GenBank, and the skills to take on more advanced bioinformatics programming. Some of the later chapters focus in greater detail on specific bioinformatics topics. This book is suitable for use as a classroom textbook, for self-study, and as a reference.The book covers: Programming basics and working with DNA sequences and strings Debugging your code Simulating gene mutations using random number generators Regular expressions and finding motifs in data Arrays, hashes, and relational databases Regular expressions and restriction maps Using Perl to parse PDB records, annotations in GenBank, and BLAST output

Author: Roger Bilisoly
Publisher: John Wiley & Sons
ISBN: 1118210506
Category : Computers
Languages : en
Pages : 306

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Book Description
Provides readers with the methods, algorithms, and means to perform text mining tasks This book is devoted to the fundamentals of text mining using Perl, an open-source programming tool that is freely available via the Internet (www.perl.org). It covers mining ideas from several perspectives--statistics, data mining, linguistics, and information retrieval--and provides readers with the means to successfully complete text mining tasks on their own. The book begins with an introduction to regular expressions, a text pattern methodology, and quantitative text summaries, all of which are fundamental tools of analyzing text. Then, it builds upon this foundation to explore: Probability and texts, including the bag-of-words model Information retrieval techniques such as the TF-IDF similarity measure Concordance lines and corpus linguistics Multivariate techniques such as correlation, principal components analysis, and clustering Perl modules, German, and permutation tests Each chapter is devoted to a single key topic, and the author carefully and thoughtfully introduces mathematical concepts as they arise, allowing readers to learn as they go without having to refer to additional books. The inclusion of numerous exercises and worked-out examples further complements the book's student-friendly format. Practical Text Mining with Perl is ideal as a textbook for undergraduate and graduate courses in text mining and as a reference for a variety of professionals who are interested in extracting information from text documents.

Author: D. Curtis Jamison
Publisher: John Wiley & Sons
ISBN: 9780471430599
Category : Medical
Languages : en
Pages : 206

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Book Description
Working on the assumption that the reader has no formal training in programming, Perl Programming for Biologists demonstrates how Perl is used to solve biological problems. Each chapter opens with a set of learning objectives, provides numerous review questions and self-study exercises, and concludes with a bulleted summary of key points. The author incorporates numerous real-life examples throughout the text. Upon completing the book, readers are able to quickly perform such tasks as correcting recurring errors in spreadsheets, scanning a Fasta sequence for every occurrence of an EcoRI site, adapting other writers' scripts to one's own purposes, and most important, writing reusable and maintainable scripts that spare the rote repetition of code.

Author: Caroline St. Clair
Publisher: Jones & Bartlett Learning
ISBN: 1284066002
Category : Science
Languages : en
Pages : 377

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Book Description
Thoroughly revised and updated, Exploring Bioinformatics: A Project-Based Approach, Second Edition is intended for an introductory course in bioinformatics at the undergraduate level. Through hands-on projects, students are introduced to current biological problems and then explore and develop bioinformatic solutions to these issues. Each chapter presents a key problem, provides basic biological concepts, introduces computational techniques to address the problem, and guides students through the use of existing web-based tools and software solutions. This progression prepares students to tackle the On-Your-Own Project, where they develop their own software solutions. Topics such as antibiotic resistance, genetic disease, and genome sequencing provide context and relevance to capture student interest.

Author: Caroline St. Clair
Publisher: Jones & Bartlett Publishers
ISBN: 128402346X
Category : Computers
Languages : en
Pages : 309

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Book Description
Thoroughly revised and updated, Exploring Bioinformatics: A Project-Based Approach, Second Edition is intended for an introductory course in bioinformatics at the undergraduate level. Through hands-on projects, students are introduced to current biological problems and then explore and develop bioinformatic solutions to these issues. Each chapter presents a key problem, provides basic biological concepts, introduces computational techniques to address the problem, and guides students through the use of existing web-based tools and software solutions. This progression prepares students to tackle the On-Your-Own Project, where they develop their own software solutions. Topics such as antibiotic resistance, genetic disease, and genome sequencing provide context and relevance to capture student interest.

Author: Gabriel Valiente
Publisher: CRC Press
ISBN: 1420069748
Category : Computers
Languages : en
Pages : 370

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Book Description
Emphasizing the search for patterns within and between biological sequences, trees, and graphs, Combinatorial Pattern Matching Algorithms in Computational Biology Using Perl and R shows how combinatorial pattern matching algorithms can solve computational biology problems that arise in the analysis of genomic, transcriptomic, proteomic, metabolomic

Author: David Scott
Publisher: Lulu.com
ISBN: 1300607211
Category : Computers
Languages : en
Pages : 288

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Book Description
Go from scripts to functions to programs. Learn bio programming with the Perl development paradigm. Learn to write tested, documented, object oriented code the Perl way.

Author: Röbbe Wünschiers
Publisher: Springer Science & Business Media
ISBN: 3642185525
Category : Science
Languages : en
Pages : 291

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Book Description
-Teaches the reader how to use Unix, which is the key to basic computing and allows the most flexibility for bioinformatics applications -Written specifically with the needs of molecular biologists in mind -Easy to follow, written for beginners with no computational knowledge -Includes examples from biological data analysis -Can be use either for self-teaching or in courses

Author: John C. Lucchesi
Publisher: Oxford University Press
ISBN: 0192567160
Category : Science
Languages : en
Pages : 305

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Book Description
Epigenetics is the study of heritable changes in gene function that do not involve changes in the DNA sequence. These changes, consisting principally of DNA methylation, histone modifications, and non-coding RNAs, maintain or modulate the initial impact of regulatory factors that recognize and associate with particular genomic sequences. Epigenetic modifications are manifest in all aspects of normal cellular differentiation and function, but they can also have damaging effects that result in pathologies such as cancer. Research is continuously uncovering the role of epigenetics in a variety of human disorders, providing new avenues for therapeutic interventions and advances in regenerative medicine. This book's primary goal is to establish a framework that can be used to understand the basis of epigenetic regulation and to appreciate both its derivation from genetics and interdependence with genetic mechanisms. A further aim is to highlight the role played by the three-dimensional organization of the genetic material itself (the complex of DNA, histones and non-histone proteins referred to as chromatin), and its distribution within a functionally compartmentalized nucleus. This architectural organization of the genome plays a major role in the subsequent retrieval, interpretation, and execution of both genetic and epigenetic information.