Perioperative Chemotherapy

Perioperative Chemotherapy PDF Author: U. Metzger
Publisher: Springer Science & Business Media
ISBN: 3642824323
Category : Medical
Languages : en
Pages : 170

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Book Description
One reason for failure to cure solid tumors by surgery appears to be the impossibility of controlling metastases that are present but latent at the time of operation. This failure is a common clinical experience with aggressive neoplasms. but it is not always appreciated in tumors with longer survival times. e. g .• breast and colon cancer. In addition. recent evidence indicates that after resection of a primary tumor micrometas tases from it might be enhanced by suppression of immune and reticu loendothelial functions of the host. Other factors, such as increase of coagulability and stress in the perioperative period, can also promote tumor growth. The development of new metastases might be facilitated by cells forced into the circulation during operative manipulations. Such events could be important for the outcome of treatment and it is suggested that preventive measures should be directed to this systemic component of solid tumors. Radical surgery can reduce the number of tumor cells to a subclinical 3 6 stage (10 to 10 cells) in which chemotherapy might be more effective than in advanced stages. Chemotherapy, on the other hand, might aggravate the surgical morbidity by influencing the wound healing pro cess, by decreasing the immune response, and/or by toxicity to the bone marrow and to the gastrointestinal tract, for example.

Perioperative Chemotherapy

Perioperative Chemotherapy PDF Author: U. Metzger
Publisher: Springer Science & Business Media
ISBN: 3642824323
Category : Medical
Languages : en
Pages : 170

Get Book Here

Book Description
One reason for failure to cure solid tumors by surgery appears to be the impossibility of controlling metastases that are present but latent at the time of operation. This failure is a common clinical experience with aggressive neoplasms. but it is not always appreciated in tumors with longer survival times. e. g .• breast and colon cancer. In addition. recent evidence indicates that after resection of a primary tumor micrometas tases from it might be enhanced by suppression of immune and reticu loendothelial functions of the host. Other factors, such as increase of coagulability and stress in the perioperative period, can also promote tumor growth. The development of new metastases might be facilitated by cells forced into the circulation during operative manipulations. Such events could be important for the outcome of treatment and it is suggested that preventive measures should be directed to this systemic component of solid tumors. Radical surgery can reduce the number of tumor cells to a subclinical 3 6 stage (10 to 10 cells) in which chemotherapy might be more effective than in advanced stages. Chemotherapy, on the other hand, might aggravate the surgical morbidity by influencing the wound healing pro cess, by decreasing the immune response, and/or by toxicity to the bone marrow and to the gastrointestinal tract, for example.

Anesthesia and Perioperative Care of the High-Risk Patient

Anesthesia and Perioperative Care of the High-Risk Patient PDF Author: Ian McConachie
Publisher: Cambridge University Press
ISBN: 1107690579
Category : Medical
Languages : en
Pages : 501

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Book Description
A concise summary of perioperative management of high-risk surgical patients, bridging the gap between the operating theatre and ICU.

Disease Control Priorities, Third Edition (Volume 1)

Disease Control Priorities, Third Edition (Volume 1) PDF Author: Haile T. Debas
Publisher: World Bank Publications
ISBN: 1464803676
Category : Medical
Languages : en
Pages : 445

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Book Description
Essential Surgery is part of a nine volume series for Disease Control Priorities which focuses on health interventions intended to reduce morbidity and mortality. The Essential Surgery volume focuses on four key aspects including global financial responsibility, emergency procedures, essential services organization and cost analysis.

Decision Making in Perioperative Medicine: Clinical Pearls

Decision Making in Perioperative Medicine: Clinical Pearls PDF Author: Steven L. Cohn
Publisher: McGraw Hill Professional
ISBN: 1260468119
Category : Medical
Languages : en
Pages : 351

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Book Description
Minimize risk for every surgery-bound patient with this concise, high-yield clinical reference “The accuracy and readability of this [book] is excellent... the writing style is appropriate, informative, and suitable for the primary care clinician. The topics are well researched [and] the clinical recommendations reflect the most current guidelines.”—Robert C. Lavender, MD, FACP “The editor and contributing authors are all highly credible authorities and experienced clinicians... This is an extremely well-written, evidence-based text that fills a real gap. It should be useful not only to its intended audience, but also to surgeons and surgical trainees who often provide the initial management of these situations in the absence of consultants.”—Doody’s Review Service With new surgical advances and innovations, more older, sicker, higher-risk patients are undergoing surgery. Expertly assessing and managing patients with comorbidities who are undergoing surgical procedures is an absolutely critical task today—and Decision Making in Perioperative Medicine: Clinical Pearls will ensure that you make the right decisions through every step of the process. Which risk calculator should you use? How long should you delay surgery after percutaneous coronary intervention? Should the patient continue taking aspirin? How long before surgery should you stop a direct-acting oral anticoagulant? Decision Making in Perioperative Medicine: Clinical Pearls answers your questions when it comes to perioperative care. Filled with algorithms, tables, and clinical pearls, this practical resource is organized into three sections: Key takeaways on preoperative evaluation, testing, anesthesia, and medication management Expert guidance on evaluating the effect of comorbidities on surgical outcome and providing strategies for medical optimization to minimize risk Review of common postoperative medical complications and treatment Whether you’re a hospitalist, internist, family physician, anesthesiologist, physician assistant, or nurse practitioner, Decision Making in Perioperative Medicine: Clinical Pearls provides the evidence-based information and insights you need to make sure every surgery-bound patient receives the quality of care and management they deserve.

Perioperative Care of the Cancer Patient E-Book

Perioperative Care of the Cancer Patient E-Book PDF Author: Carin A. Hagberg
Publisher: Elsevier Health Sciences
ISBN: 032369585X
Category : Medical
Languages : en
Pages : 659

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Book Description
More than 80% of patients with cancer will need the services of anesthesiology and perioperative medicine, intensive care medicine, and pain management specialists during their cancer journey for diagnostic, therapeutic, and symptom management needs, as well as for the management of recurrent disease, secondary cancers, and ongoing non-oncologic surgical needs during survivorship. Perioperative Care of the Cancer Patient is today's most up-to-date, authoritative, comprehensive reference on the acute care of surgical patients with cancer, from a team of international experts in this emerging and dynamic specialty. - Covers current clinical practice and perioperative care guidelines during the entire cancer journey for both adult and pediatric patients. - Includes a diverse array of topics on cancer care, such as cancer epidemiology, cancer biology, ethics in cancer care delivery, value proposition in cancer care, opportunities and challenges with research programs in perioperative cancer care, application of big data and computational sciences in cancer medicine and care delivery, and the MD Anderson Cancer Center Moon Shots Program®. - Discusses newer cancer therapies and their perioperative implications, functional assessment and prehabilitation, enhanced recovery programs in cancer care, challenges with novel cancer therapies in the care of the critically ill cancer patient, chronic and interventional pain management in patients with cancer, and more. - An educational resource and clinical reference for surgeons, anesthesia practitioners, hospitalists, internists, pain physicians, intensivists, basic science researchers, and all clinicians involved in the acute care of surgical patients with cancer. - Enhanced eBook version included with purchase. Your enhanced eBook allows you to access all of the text, figures, and references from the book on a variety of devices.

Atlas of Imaging in Cardio-Oncology

Atlas of Imaging in Cardio-Oncology PDF Author: Richard M. Steingart
Publisher: Springer Nature
ISBN: 3030709981
Category : Medical
Languages : en
Pages : 316

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Book Description
This atlas provides a practically applicable didatic case-based guide to the use of cardiac imaging in patient care during and after cancer therapy. It features detailed information on a variety of imaging modalities, including transesophageal echocardiography, magnetic resonance angiography and positron emission tomography. A range of actual patient presentations are included covering both diagnosis and management during curative and palliative surgery, as well as cancer pharmacotherapy with the use of drugs including Trastuzumab, Anthracycline, Cisplatin and Carboplatin. Topics relevant to survivorship are also described. Atlas of Imaging in Cardio-Oncology enables the reader to develop a deep understanding of how to utilise a variety of imaging modalities used in cardio-oncology in a range of scenarios. It provides a critical and timely resource for the trainee and experienced cardiologist, oncologist and radiologist.

Textbook of Onco-Anesthesiology

Textbook of Onco-Anesthesiology PDF Author: Rakesh Garg
Publisher: Springer Nature
ISBN: 9811600066
Category : Medical
Languages : en
Pages : 539

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Book Description
This book covers all essential evidence on perioperative care and anesthetic concerns for cancer surgeries, including the evaluation and assessment of patients’ schedule for cancer surgeries, perioperative anesthetic management of various cancers, perioperative analgesia for cancer surgeries, and issues related to inoperable cancers. It reviews anesthetic considerations of all cancer types as there is a wide variation in anesthetic requirements in this subset of patients. Cancer surgeries are on the rise worldwide and healthcare facilities with cancer as a core specialty are emerging quickly around the globe. As cancer is on rise and efficient surgical management is available, more and more patients are being treated surgically. However, cancer surgeries are complicated, have varied concerns and these are not covered sufficiently in presently available textbooks of anesthesiology. This book fulfills the growing need for complete and comprehensive textbook of onco-anesthesia and fills the gap in the current texts that do not exclusively cover anesthesia for cancer surgeries. This textbook serves as a comprehensive but quick guide for trainee residents/fellows and practicing anesthesiologists, clinicians and surgeons.

Multidisciplinary Approach to Surgical Oncology Patients

Multidisciplinary Approach to Surgical Oncology Patients PDF Author: M. D. Ray
Publisher: Springer Nature
ISBN: 9811576998
Category : Medical
Languages : en
Pages : 358

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Book Description
The book covers the basic concept of surgical and oncosurgical disciplines as a whole, as well as the management of surgical patients from pre-op preparation to discharge, i.e., all the basics needed for a successful outcome for oncosurgical patients. It covers surgical safety, the consumer protection act, medico-legal aspects, the importance of documentation, research and publications, and managing complications. The respective chapters cover pre-operative, intra-operative, and ICU management of cancer patients, based on a multi-disciplinary approach. Additionally, they highlight recent advances in surgical oncology and so-called incurable cancers. Edited and written by an interdisciplinary team of experts in oncology and palliative care, the book is intended as a clinically useful guide to the overlapping topics of pain management in cancer patients and the treatment of cancer in patients with multiple co-morbidities like cardiovascular, respiratory disease, hypertension and diabetes mellitus. Given its scope, it will benefit multi-disciplinary oncologists, pain, palliative and intensive care experts, as well as students of surgical disciplines, from MBBS, MS and DNB, to MRCS, MCh and FRCS.

Surgical Management of Advanced Pelvic Cancer

Surgical Management of Advanced Pelvic Cancer PDF Author: Desmond C. Winter
Publisher: John Wiley & Sons
ISBN: 1119518407
Category : Medical
Languages : en
Pages : 324

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Book Description
An innovative guide to the practice of pelvic exenterative surgery for the management of advanced pelvic neoplasms Exenterative surgery plays an important role in the management of advanced pelvic cancer. However, while a large body of evidence regarding outcomes following pelvic exenteration now exists, practical strategies and management options remain unclear. Surgical Management of Advanced Pelvic Cancer addresses this problem by assembling world-leaders in the field to provide insights into the latest techniques and best practices. It includes detailed coverage of: Surgical anatomy Operative approaches and exenterative techniques Reconstruction options Current evidence on survival and quality of life outcomes Featuring essential information for those managing patients with advanced pelvic neoplasms, Surgical Management of Advanced Pelvic Cancer consolidates the latest data and practical advice in one indispensable guide.

Oxford Textbook of Fundamentals of Surgery

Oxford Textbook of Fundamentals of Surgery PDF Author: William E. G. Thomas
Publisher: Oxford University Press
ISBN: 0199665540
Category : Medical
Languages : en
Pages : 849

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Book Description
A definitive, accessible, and reliable resource which provides a solid foundation of the knowledge and basic science needed to hone all of the core surgical skills used in surgical settings. Presented in a clear and accessible way it addresses the cross-specialty aspects of surgery applicable to all trainees.