Author: Rebekah Heinrichs
Publisher: AAPC Publishing
ISBN: 9781931282185
Category : Education
Languages : en
Pages : 204
Book Description
A 2002 study from Comprehensive Issues in Pediatric Nursing found that 94 percent of students with Asperger Syndrome face torment from their peers. Indeed, some of their behaviors and characteristics that others see as "different" make many of these children easy targets for frequent and severe bullying. This book takes a frank look at the different types of bullying and what adults must do to curb bullying, helping prevent the often lifelong effects of this behavior on its victims. Practical strategies and solutions at the school, class and individual level are presented.
Perfect Targets
Author: Rebekah Heinrichs
Publisher: AAPC Publishing
ISBN: 9781931282185
Category : Education
Languages : en
Pages : 204
Book Description
A 2002 study from Comprehensive Issues in Pediatric Nursing found that 94 percent of students with Asperger Syndrome face torment from their peers. Indeed, some of their behaviors and characteristics that others see as "different" make many of these children easy targets for frequent and severe bullying. This book takes a frank look at the different types of bullying and what adults must do to curb bullying, helping prevent the often lifelong effects of this behavior on its victims. Practical strategies and solutions at the school, class and individual level are presented.
Publisher: AAPC Publishing
ISBN: 9781931282185
Category : Education
Languages : en
Pages : 204
Book Description
A 2002 study from Comprehensive Issues in Pediatric Nursing found that 94 percent of students with Asperger Syndrome face torment from their peers. Indeed, some of their behaviors and characteristics that others see as "different" make many of these children easy targets for frequent and severe bullying. This book takes a frank look at the different types of bullying and what adults must do to curb bullying, helping prevent the often lifelong effects of this behavior on its victims. Practical strategies and solutions at the school, class and individual level are presented.
The 100 Best Astrophotography Targets
Author: Ruben Kier
Publisher: Springer Science & Business Media
ISBN: 1441906037
Category : Science
Languages : en
Pages : 365
Book Description
Any amateur astronomer who is interested in astrophotography, particularly if just getting started, needs to know what objects are best for imaging in each month of the year. These are not necessarily the same objects that are the most spectacular or intriguing visually. The camera reveals different things and has different requirements. What objects in the sky tonight are large enough, bright enough, and high enough to be photographed? This book reveals, for each month of the year, the choicest celestial treasures within the reach of a commercial CCD camera. Helpful hints and advice on framing, exposures, and filters are included. Each deep sky object is explained in beautiful detail, so that observers will gain a richer understanding of these astronomical objects. This is not a book that dwells on the technology of CCD, Webcam, wet, or other types of astrophotography. Neither is it a book about in-depth computer processing of the images (although this topic is included). Detailed discussions of these topics can be found in other publications. This book focuses on what northern latitude objects to image at any given time of the year to get the most spectacular results.
Publisher: Springer Science & Business Media
ISBN: 1441906037
Category : Science
Languages : en
Pages : 365
Book Description
Any amateur astronomer who is interested in astrophotography, particularly if just getting started, needs to know what objects are best for imaging in each month of the year. These are not necessarily the same objects that are the most spectacular or intriguing visually. The camera reveals different things and has different requirements. What objects in the sky tonight are large enough, bright enough, and high enough to be photographed? This book reveals, for each month of the year, the choicest celestial treasures within the reach of a commercial CCD camera. Helpful hints and advice on framing, exposures, and filters are included. Each deep sky object is explained in beautiful detail, so that observers will gain a richer understanding of these astronomical objects. This is not a book that dwells on the technology of CCD, Webcam, wet, or other types of astrophotography. Neither is it a book about in-depth computer processing of the images (although this topic is included). Detailed discussions of these topics can be found in other publications. This book focuses on what northern latitude objects to image at any given time of the year to get the most spectacular results.
Atomic Habits
Author: James Clear
Publisher: Penguin
ISBN: 0735211299
Category : Business & Economics
Languages : en
Pages : 321
Book Description
The #1 New York Times bestseller. Over 20 million copies sold! Translated into 60+ languages! Tiny Changes, Remarkable Results No matter your goals, Atomic Habits offers a proven framework for improving--every day. James Clear, one of the world's leading experts on habit formation, reveals practical strategies that will teach you exactly how to form good habits, break bad ones, and master the tiny behaviors that lead to remarkable results. If you're having trouble changing your habits, the problem isn't you. The problem is your system. Bad habits repeat themselves again and again not because you don't want to change, but because you have the wrong system for change. You do not rise to the level of your goals. You fall to the level of your systems. Here, you'll get a proven system that can take you to new heights. Clear is known for his ability to distill complex topics into simple behaviors that can be easily applied to daily life and work. Here, he draws on the most proven ideas from biology, psychology, and neuroscience to create an easy-to-understand guide for making good habits inevitable and bad habits impossible. Along the way, readers will be inspired and entertained with true stories from Olympic gold medalists, award-winning artists, business leaders, life-saving physicians, and star comedians who have used the science of small habits to master their craft and vault to the top of their field. Learn how to: make time for new habits (even when life gets crazy); overcome a lack of motivation and willpower; design your environment to make success easier; get back on track when you fall off course; ...and much more. Atomic Habits will reshape the way you think about progress and success, and give you the tools and strategies you need to transform your habits--whether you are a team looking to win a championship, an organization hoping to redefine an industry, or simply an individual who wishes to quit smoking, lose weight, reduce stress, or achieve any other goal.
Publisher: Penguin
ISBN: 0735211299
Category : Business & Economics
Languages : en
Pages : 321
Book Description
The #1 New York Times bestseller. Over 20 million copies sold! Translated into 60+ languages! Tiny Changes, Remarkable Results No matter your goals, Atomic Habits offers a proven framework for improving--every day. James Clear, one of the world's leading experts on habit formation, reveals practical strategies that will teach you exactly how to form good habits, break bad ones, and master the tiny behaviors that lead to remarkable results. If you're having trouble changing your habits, the problem isn't you. The problem is your system. Bad habits repeat themselves again and again not because you don't want to change, but because you have the wrong system for change. You do not rise to the level of your goals. You fall to the level of your systems. Here, you'll get a proven system that can take you to new heights. Clear is known for his ability to distill complex topics into simple behaviors that can be easily applied to daily life and work. Here, he draws on the most proven ideas from biology, psychology, and neuroscience to create an easy-to-understand guide for making good habits inevitable and bad habits impossible. Along the way, readers will be inspired and entertained with true stories from Olympic gold medalists, award-winning artists, business leaders, life-saving physicians, and star comedians who have used the science of small habits to master their craft and vault to the top of their field. Learn how to: make time for new habits (even when life gets crazy); overcome a lack of motivation and willpower; design your environment to make success easier; get back on track when you fall off course; ...and much more. Atomic Habits will reshape the way you think about progress and success, and give you the tools and strategies you need to transform your habits--whether you are a team looking to win a championship, an organization hoping to redefine an industry, or simply an individual who wishes to quit smoking, lose weight, reduce stress, or achieve any other goal.
Hardware and Housefurnishing Goods
Author:
Publisher:
ISBN:
Category :
Languages : en
Pages : 656
Book Description
Publisher:
ISBN:
Category :
Languages : en
Pages : 656
Book Description
Super Skills
Author: Judith Coucouvanis
Publisher: AAPC Publishing
ISBN: 1931282676
Category : Education
Languages : en
Pages : 370
Book Description
The title says it all! Super Skills: A Social Skills Group Program for Children with Asperger Syndrome, High-Functioning Autism and Related Challenges is SUPER at many levels. Based on a thorough and comprehensive understanding of the unique characteristics of individuals with ASD, Judy Coucouvanis presents 30 lessons grouped under four types of skills necessary for social success: fundamental skills, social initiation skills, getting along with others, and social response skills. Each lesson is highly structured and organized, making it easy for even inexperienced teachers and other group leaders to follow and implement successfully. A series of practical checklists and other instruments provide a solid foundation for assessing students? social skills levels and subsequent planning.
Publisher: AAPC Publishing
ISBN: 1931282676
Category : Education
Languages : en
Pages : 370
Book Description
The title says it all! Super Skills: A Social Skills Group Program for Children with Asperger Syndrome, High-Functioning Autism and Related Challenges is SUPER at many levels. Based on a thorough and comprehensive understanding of the unique characteristics of individuals with ASD, Judy Coucouvanis presents 30 lessons grouped under four types of skills necessary for social success: fundamental skills, social initiation skills, getting along with others, and social response skills. Each lesson is highly structured and organized, making it easy for even inexperienced teachers and other group leaders to follow and implement successfully. A series of practical checklists and other instruments provide a solid foundation for assessing students? social skills levels and subsequent planning.
Shooting and Fishing
Author:
Publisher:
ISBN:
Category : Firearms
Languages : en
Pages : 532
Book Description
Publisher:
ISBN:
Category : Firearms
Languages : en
Pages : 532
Book Description
A Role for the Let-7 Primary MicroRNA in Target Gene Recognition and Repression
Author: Robin Deis Trujillo
Publisher: Stanford University
ISBN:
Category :
Languages : en
Pages : 222
Book Description
MicroRNA (miRNA) genes produce three noncoding RNA products: the long primary transcript (pri-miRNA), the ~70 nucleotide pre-miRNA, and the ~22-nt mature miRNA. Only the mature miRNA is considered to be the functional species of a miRNA gene in recognizing cognate target mRNAs and modulating their expression. However, mature miRNAs are processed from the primary transcript through sequential endonucleolytic steps. As a result, the mature miRNA sequence is present in all three RNA products of a miRNA gene. It has thus been intrinsically difficult to determine the contribution of each miRNA gene product to target repression. In fact, direct functional roles for pri- and pre-miRNAs have never been ruled out. Here we show that pri- and pre-miRNAs may not be mere transitory intermediates of mature miRNA biogenesis. We found that ectopic expression of the C. elegans miRNA gene let-7 (cel-let-7) in human culture cells results in the production of truncated pre- and mature miRNAs that lack the first two 5' nucleotides, one of which is the first nucleotide of the miRNA seed region (nucleotide SD1). We found this nucleotide to be required for repression of target reporters by cel-let-7 in these cells, demonstrating that pri-let-7 may have a direct role in target repression. Further, we show that the nucleotide sequence and structure of both the pri-/pre-let-7 loop and stem regions play a key role in miRNA gene function in reporter assays. In vitro and in vivo analyses indicated the significance of these regions may be in the mediation of a physical interaction between pri-let-7 and target RNAs. These observations suggest that regulatory information encoded in the structured pri-miRNAs, but absent from mature miRNAs, could be directly interpreted for target recognition and repression through RNA:RNA interaction. Intriguingly, some mutations in the loop nucleotide sequence also restored processing of the 5' ends of C. elegans pre- and mature let-7 in culture cells, demonstrating that the pri-/pre-miRNA loop region can also regulate the precision of mature miRNA biogenesis. Importantly, in the presence of functional pre- and mature let-7, cel-let-7 activity in target repression consists of both SD1-independent and SD1-dependent components, implying potential contributions by both pri- and mature let-7. Finally, we interrogated the effects of pri-/pre-let-7 loop mutations on their ability to rescue a let-7 loss-of-function mutant phenotype in C. elegans. Our results indicate decreased significance of these parameters in the control of worm vulval development, although context-dependent differences in mature miRNA biogenesis between heterologous culture and live animals may partially explain this discrepancy. Taken together the work presented here reveals a novel layer of regulatory complexity encoded in long primary miRNAs that may have broad implications in understanding the mechanisms by which miRNA genes control target expression.
Publisher: Stanford University
ISBN:
Category :
Languages : en
Pages : 222
Book Description
MicroRNA (miRNA) genes produce three noncoding RNA products: the long primary transcript (pri-miRNA), the ~70 nucleotide pre-miRNA, and the ~22-nt mature miRNA. Only the mature miRNA is considered to be the functional species of a miRNA gene in recognizing cognate target mRNAs and modulating their expression. However, mature miRNAs are processed from the primary transcript through sequential endonucleolytic steps. As a result, the mature miRNA sequence is present in all three RNA products of a miRNA gene. It has thus been intrinsically difficult to determine the contribution of each miRNA gene product to target repression. In fact, direct functional roles for pri- and pre-miRNAs have never been ruled out. Here we show that pri- and pre-miRNAs may not be mere transitory intermediates of mature miRNA biogenesis. We found that ectopic expression of the C. elegans miRNA gene let-7 (cel-let-7) in human culture cells results in the production of truncated pre- and mature miRNAs that lack the first two 5' nucleotides, one of which is the first nucleotide of the miRNA seed region (nucleotide SD1). We found this nucleotide to be required for repression of target reporters by cel-let-7 in these cells, demonstrating that pri-let-7 may have a direct role in target repression. Further, we show that the nucleotide sequence and structure of both the pri-/pre-let-7 loop and stem regions play a key role in miRNA gene function in reporter assays. In vitro and in vivo analyses indicated the significance of these regions may be in the mediation of a physical interaction between pri-let-7 and target RNAs. These observations suggest that regulatory information encoded in the structured pri-miRNAs, but absent from mature miRNAs, could be directly interpreted for target recognition and repression through RNA:RNA interaction. Intriguingly, some mutations in the loop nucleotide sequence also restored processing of the 5' ends of C. elegans pre- and mature let-7 in culture cells, demonstrating that the pri-/pre-miRNA loop region can also regulate the precision of mature miRNA biogenesis. Importantly, in the presence of functional pre- and mature let-7, cel-let-7 activity in target repression consists of both SD1-independent and SD1-dependent components, implying potential contributions by both pri- and mature let-7. Finally, we interrogated the effects of pri-/pre-let-7 loop mutations on their ability to rescue a let-7 loss-of-function mutant phenotype in C. elegans. Our results indicate decreased significance of these parameters in the control of worm vulval development, although context-dependent differences in mature miRNA biogenesis between heterologous culture and live animals may partially explain this discrepancy. Taken together the work presented here reveals a novel layer of regulatory complexity encoded in long primary miRNAs that may have broad implications in understanding the mechanisms by which miRNA genes control target expression.
The Welsh Answering System
Author: Bob Morris Jones
Publisher: Walter de Gruyter
ISBN: 3110800594
Category : Language Arts & Disciplines
Languages : en
Pages : 385
Book Description
TRENDS IN LINGUISTICS is a series of books that open new perspectives in our understanding of language. The series publishes state-of-the-art work on core areas of linguistics across theoretical frameworks as well as studies that provide new insights by building bridges to neighbouring fields such as neuroscience and cognitive science. TRENDS IN LINGUISTICS considers itself a forum for cutting-edge research based on solid empirical data on language in its various manifestations, including sign languages. It regards linguistic variation in its synchronic and diachronic dimensions as well as in its social contexts as important sources of insight for a better understanding of the design of linguistic systems and the ecology and evolution of language. TRENDS IN LINGUISTICS publishes monographs and outstanding dissertations as well as edited volumes, which provide the opportunity to address controversial topics from different empirical and theoretical viewpoints. High quality standards are ensured through anonymous reviewing.
Publisher: Walter de Gruyter
ISBN: 3110800594
Category : Language Arts & Disciplines
Languages : en
Pages : 385
Book Description
TRENDS IN LINGUISTICS is a series of books that open new perspectives in our understanding of language. The series publishes state-of-the-art work on core areas of linguistics across theoretical frameworks as well as studies that provide new insights by building bridges to neighbouring fields such as neuroscience and cognitive science. TRENDS IN LINGUISTICS considers itself a forum for cutting-edge research based on solid empirical data on language in its various manifestations, including sign languages. It regards linguistic variation in its synchronic and diachronic dimensions as well as in its social contexts as important sources of insight for a better understanding of the design of linguistic systems and the ecology and evolution of language. TRENDS IN LINGUISTICS publishes monographs and outstanding dissertations as well as edited volumes, which provide the opportunity to address controversial topics from different empirical and theoretical viewpoints. High quality standards are ensured through anonymous reviewing.
The Mom's Guide to Asperger Syndrome
Author: Jan Johnston-Tyler
Publisher: AAPC Publishing
ISBN: 9781931282420
Category : Family & Relationships
Languages : en
Pages : 342
Book Description
he Mom's Guide to Asperger Syndrome and Related Disorders is written primarily for parents of children who have newly been diagnosed with Asperger Syndrome. It is especially a great resource for the preschool through elementary school years. The book draws from the author's personal experience both as the mom of a son with Asperger Syndrome and her study of and work with children and adolescents with special needs. The result is a practical guide, written for other Aspie parents in a clear, concise, and sometimes humorous tone.This user-friendly book leaves no stone unturned, as it explains, in a friendly, familiar voice, situations and issues that all parents with an AS child will encounter at one point or another. Above all else, the book arms parents with basic, sound information empowering them to seek out the very best services and programs for their child.From dealing with sensory issues and bullying to staying on top of homework, The Mom's Guide to Asperger Syndrome and Related Disorders offers easy-to-use suggestions. The Mom's Guide to Asperger Syndrome and related disorders should be used as a practical, valuable reference throughout the years.
Publisher: AAPC Publishing
ISBN: 9781931282420
Category : Family & Relationships
Languages : en
Pages : 342
Book Description
he Mom's Guide to Asperger Syndrome and Related Disorders is written primarily for parents of children who have newly been diagnosed with Asperger Syndrome. It is especially a great resource for the preschool through elementary school years. The book draws from the author's personal experience both as the mom of a son with Asperger Syndrome and her study of and work with children and adolescents with special needs. The result is a practical guide, written for other Aspie parents in a clear, concise, and sometimes humorous tone.This user-friendly book leaves no stone unturned, as it explains, in a friendly, familiar voice, situations and issues that all parents with an AS child will encounter at one point or another. Above all else, the book arms parents with basic, sound information empowering them to seek out the very best services and programs for their child.From dealing with sensory issues and bullying to staying on top of homework, The Mom's Guide to Asperger Syndrome and Related Disorders offers easy-to-use suggestions. The Mom's Guide to Asperger Syndrome and related disorders should be used as a practical, valuable reference throughout the years.
Molecular Beacons
Author: Chaoyong James Yang
Publisher: Springer Science & Business Media
ISBN: 3642391095
Category : Science
Languages : en
Pages : 201
Book Description
Molecular Beacons explains working principle of molecular beacons, discusses their design, synthesis, purification and characterization, explores their thermodynamic and kinetic properties, and more importantly, reviews their in vivo and in vitro applications with the emphasis on the design and modification of molecular beacons for in vivo mRNA imaging applications. This book is designed to bring together in a single resource an organized and comprehensive view of molecular beacons and will be a valuable resource for academic, clinical and industrial scientists and graduate students who may consider exploring molecular beacons in their research or practice. Chaoyong James Yang is the Lu Jiaxi Professor of Chemistry at Xiamen University, China. Weihong Tan is a Distinguished Professor of Chemistry and Biomedical Engineering at Hunan University, China and also a University of Florida Distinguished Professor and V. T. and Louis Jackson Professor of Chemistry at the University of Florida, USA.
Publisher: Springer Science & Business Media
ISBN: 3642391095
Category : Science
Languages : en
Pages : 201
Book Description
Molecular Beacons explains working principle of molecular beacons, discusses their design, synthesis, purification and characterization, explores their thermodynamic and kinetic properties, and more importantly, reviews their in vivo and in vitro applications with the emphasis on the design and modification of molecular beacons for in vivo mRNA imaging applications. This book is designed to bring together in a single resource an organized and comprehensive view of molecular beacons and will be a valuable resource for academic, clinical and industrial scientists and graduate students who may consider exploring molecular beacons in their research or practice. Chaoyong James Yang is the Lu Jiaxi Professor of Chemistry at Xiamen University, China. Weihong Tan is a Distinguished Professor of Chemistry and Biomedical Engineering at Hunan University, China and also a University of Florida Distinguished Professor and V. T. and Louis Jackson Professor of Chemistry at the University of Florida, USA.