Patterns of integration of viral DNA sequences in the genomes of adenovirus type 12-transformed [transformed] hamster cells and methylation of the integrated viral DNA

Patterns of integration of viral DNA sequences in the genomes of adenovirus type 12-transformed [transformed] hamster cells and methylation of the integrated viral DNA PDF Author: Diane Jane Kühn
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Languages : de
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Patterns of integration of viral DNA sequences in the genomes of adenovirus type 12-transformed hamster cells and methylation of the integrated viral DNA

Patterns of integration of viral DNA sequences in the genomes of adenovirus type 12-transformed hamster cells and methylation of the integrated viral DNA PDF Author: Diane Jane Kühn-Sutter
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Category :
Languages : de
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Patterns of Integration of Viral DNA Sequences in the Genomes of Adenovirus Type 12-transformed Hamster Cells and Methylation of the Integrated Viral DNA

Patterns of Integration of Viral DNA Sequences in the Genomes of Adenovirus Type 12-transformed Hamster Cells and Methylation of the Integrated Viral DNA PDF Author: Diane Jane Kühn
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ISBN:
Category :
Languages : en
Pages :

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Methylation of Integrated Viral DNA Sequences in Hamster Cells Transformed by Adenovirus 12

Methylation of Integrated Viral DNA Sequences in Hamster Cells Transformed by Adenovirus 12 PDF Author:
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ISBN:
Category :
Languages : en
Pages : 4

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The Molecular Biology of Adenoviruses I

The Molecular Biology of Adenoviruses I PDF Author: W. Doerfler
Publisher: Springer Science & Business Media
ISBN: 3642694608
Category : Medical
Languages : en
Pages : 240

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Book Description
A puzzling epidemiological problem was the driving force behind the discovery of human adenoviruses by Wallace Rowe and his colleagues 30 years ago. The de velopment of a plaque assay for poliomyelitis virus in 1953 led us to the threshold of quantitative virology, and in the same year the double-helical structure of DNA was discovered and became a cornerstone of mo lecular biology. The potential of adenoviruses as research tools in the molecular and cellular biology of eukaryotic cells was recognized as early as the late 1950s and early 1960s by several investigators. Structural and biochemical stu dies dominated the early years. In 1962, some of the adenoviruses were the first human viruses shown to be oncogenic in experimental animals. Thus adenovirology offered the investigator the entire gamut of host cell interactions, productive and abortive, as well as trans formed and tumor cell systems. The possibilities that adenoviruses afforded for the study of the molecular biology and genetics of eukaryotic cells were fully rea lized in the late 1960s and the 1970s.

DNA Methylation

DNA Methylation PDF Author: J. Jost
Publisher: Birkhäuser
ISBN: 3034891180
Category : Science
Languages : en
Pages : 581

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Book Description
The occurrence of 5-methylcytosine in DNA was first described in 1948 by Hotchkiss (see first chapter). Recognition of its possible physiologi cal role in eucaryotes was first suggested in 1964 by Srinivasan and Borek (see first chapter). Since then work in a great many laboratories has established both the ubiquity of 5-methylcytosine and the catholicity of its possible regulatory function. The explosive increase in the number of publications dealing with DNA methylation attests to its importance and makes it impossible to write a comprehensive coverage of the literature within the scope of a general review. Since the publication of the 3 most recent books dealing with the subject (DNA methylation by Razin A. , Cedar H. and Riggs A. D. , 1984 Springer Verlag; Molecular Biology of DNA methylation by Adams R. L. P. and Burdon R. H. , 1985 Springer Verlag; Nucleic Acids Methylation, UCLA Symposium suppl. 128, 1989) considerable progress both in the techniques and results has been made in the field of DNA methylation. Thus we asked several authors to write chapters dealing with aspects of DNA methyla tion in which they are experts. This book should be most useful for students, teachers as well as researchers in the field of differentiation and gene regulation. We are most grateful to all our colleagues who were willing to spend much time and effort on the publication of this book. We also want to express our gratitude to Yan Chim Jost for her help in preparing this book.

The Adenoviruses

The Adenoviruses PDF Author: Harold S. Ginsberg
Publisher: Springer Science & Business Media
ISBN: 1468479350
Category : Medical
Languages : en
Pages : 620

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Book Description
The discovery of adenoviruses naturally induced a new interest in viruses of the human upper respiratory tract since previously unknown viruses infecting this portion of the human body had not been identified in 20 years, and their unique characteristics stimulated investigations into the biochemical events essential for replication of animal viruses. Indeed, the field of molecular virology has evolved during the period since their dis covery, and adenoviruses have played a major role in this development. The exciting discoveries made with adenoviruses have had such a pro found effect on knowledge in basic virology, molecular biology, viral ge netics, human and animal infections, and cell transformation that this seemed a propitious time to have some of the major contributors review this field. This volume pays tribute to the late Wallace Rowe, Robert Huebner, and Maurice Hilleman whose initial discoveries of adenoviruses have tremendously enriched virology. Harold S. Ginsberg vii Contents Chapter 1 An Overview 1 Harold S. Ginsberg Chapter 2 The Architecture of Adenoviruses M. V. Nermut I. Introduction ................................... . 5 II. Chemical and Physical Properties ................... . 6 III. Virus Capsid: Composition and Organization .......... . 7 A. Hexon ..................................... . 10 B. Penton .................................... . 12 C. Other Virus Polypeptides Associated with the Capsid 13 D. Organization of the Capsid ..................... . 14 IV. Virus Core .................................... . 15 A. Evidence for the Core Shell ..................... . 17 B. Organization of the DNA-Protein Complex (Nucleoc- sid) ....................................... . 18 C. Tentative Model of the Adenovirus Nucleocapsid ... . 22 V. Model of the Adenovirion ......................... . 29 32 References .......................................... .

The Molecular Repertoire of Adenoviruses II

The Molecular Repertoire of Adenoviruses II PDF Author: Walter Doerfler
Publisher: Springer Science & Business Media
ISBN: 3642794998
Category : Science
Languages : en
Pages : 291

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Book Description
For decades this virus system has served--and continues to do so--to pioneer investigations on the molecular biology, biochemistry and genetics of mammalian cell systems. This three volume work presents an up-to-date account of recent basic research in one of the most important experimental systems for biochemical, cell biological, genetic, virological and epidemiological investigations in mammalian molecular biology. In this, the second of three volumes, the attention is turned to such topics as DNA replication, recombination and integration, and post-transcriptional control. The chapters have been written by an international group of leading experts in their respective fields of interest.

The Expression of Integrated Viral Genes in Adenovirus Transformed Cells

The Expression of Integrated Viral Genes in Adenovirus Transformed Cells PDF Author: Marianne Wilhelmina van Maarschalkerweerd
Publisher:
ISBN:
Category : Viral cell transformation
Languages : en
Pages : 198

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DNA — Technology and Its Forensic Application

DNA — Technology and Its Forensic Application PDF Author: G. Berghaus
Publisher: Springer Science & Business Media
ISBN: 3642766323
Category : Medical
Languages : en
Pages : 326

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Book Description
All up-to-date aspects of DNA technology are discussed partly in review lectures but mostly in research articles in this volume: new methods, population statistics for different restriction fragment length polymorphisms (RFLP's), new developments dealing with the polymerase chain reaction (PCR), biostatistical aspects of single locus and multi locus profiles as well as examples of practical applications in paternity testing and forensic stain analysis. Contributors to this volume include most internationally acclaimed researchers in this field. Besides facts that are primarily of interest to forensic scientists, immunohaematologists and human geneticists should also find some aspects for their research.