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Author: Debmalya Barh
Publisher: Academic Press
ISBN: 0128170778
Category : Science
Languages : en
Pages : 476
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Book Description
Pan-genomics: Applications, Challenges, and Future Prospects covers current approaches, challenges and future prospects of pan-genomics. The book discusses bioinformatics tools and their applications and focuses on bacterial comparative genomics in order to leverage the development of precise drugs and treatments for specific organisms. The book is divided into three sections: the first, an "overview of pan-genomics and common approaches, brings the main concepts and current approaches on pan-genomics research; the second, "case studies in pan-genomics, thoroughly discusses twelve case, and the last, "current approaches and future prospects in pan-multiomics, encompasses the developments on omics studies to be applied on bacteria related studies. This book is a valuable source for bioinformaticians, genomics researchers and several members of biomedical field interested in understanding further bacterial organisms and their relationship to human health. - Covers the entire spectrum of pangenomics, highlighting the use of specific approaches, case studies and future perspectives - Discusses current bioinformatics tools and strategies for exploiting pangenomics data - Presents twelve case studies with different organisms in order to provide the audience with real examples of pangenomics applicability
Author: Debmalya Barh
Publisher: Academic Press
ISBN: 0128170778
Category : Science
Languages : en
Pages : 476
Get Book Here
Book Description
Pan-genomics: Applications, Challenges, and Future Prospects covers current approaches, challenges and future prospects of pan-genomics. The book discusses bioinformatics tools and their applications and focuses on bacterial comparative genomics in order to leverage the development of precise drugs and treatments for specific organisms. The book is divided into three sections: the first, an "overview of pan-genomics and common approaches, brings the main concepts and current approaches on pan-genomics research; the second, "case studies in pan-genomics, thoroughly discusses twelve case, and the last, "current approaches and future prospects in pan-multiomics, encompasses the developments on omics studies to be applied on bacteria related studies. This book is a valuable source for bioinformaticians, genomics researchers and several members of biomedical field interested in understanding further bacterial organisms and their relationship to human health. - Covers the entire spectrum of pangenomics, highlighting the use of specific approaches, case studies and future perspectives - Discusses current bioinformatics tools and strategies for exploiting pangenomics data - Presents twelve case studies with different organisms in order to provide the audience with real examples of pangenomics applicability
Author: Hervé Tettelin
Publisher: Springer Nature
ISBN: 3030382818
Category : Science
Languages : en
Pages : 311
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Book Description
This open access book offers the first comprehensive account of the pan-genome concept and its manifold implications. The realization that the genetic repertoire of a biological species always encompasses more than the genome of each individual is one of the earliest examples of big data in biology that opened biology to the unbounded. The study of genetic variation observed within a species challenges existing views and has profound consequences for our understanding of the fundamental mechanisms underpinning bacterial biology and evolution. The underlying rationale extends well beyond the initial prokaryotic focus to all kingdoms of life and evolves into similar concepts for metagenomes, phenomes and epigenomes. The book’s respective chapters address a range of topics, from the serendipitous emergence of the pan-genome concept and its impacts on the fields of microbiology, vaccinology and antimicrobial resistance, to the study of microbial communities, bioinformatic applications and mathematical models that tie in with complex systems and economic theory. Given its scope, the book will appeal to a broad readership interested in population dynamics, evolutionary biology and genomics.
Author: Alessio Mengoni
Publisher:
ISBN: 9781493917204
Category : Bacterial genetics
Languages : en
Pages : 298
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Book Description
Author: Nils Stein
Publisher: Springer
ISBN: 3319925288
Category : Science
Languages : en
Pages : 400
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Book Description
This book presents an overview of the state-of-the-art in barley genome analysis, covering all aspects of sequencing the genome and translating this important information into new knowledge in basic and applied crop plant biology and new tools for research and crop improvement. Unlimited access to a high-quality reference sequence is removing one of the major constraints in basic and applied research. This book summarizes the advanced knowledge of the composition of the barley genome, its genes and the much larger non-coding part of the genome, and how this information facilitates studying the specific characteristics of barley. One of the oldest domesticated crops, barley is the small grain cereal species that is best adapted to the highest altitudes and latitudes, and it exhibits the greatest tolerance to most abiotic stresses. With comprehensive access to the genome sequence, barley’s importance as a genetic model in comparative studies on crop species like wheat, rye, oats and even rice is likely to increase.
Author: Hervé Tettelin
Publisher:
ISBN: 9781013277078
Category : Science
Languages : en
Pages : 310
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Book Description
This open access book offers the first comprehensive account of the pan-genome concept and its manifold implications. The realization that the genetic repertoire of a biological species always encompasses more than the genome of each individual is one of the earliest examples of big data in biology that opened biology to the unbounded. The study of genetic variation observed within a species challenges existing views and has profound consequences for our understanding of the fundamental mechanisms underpinning bacterial biology and evolution. The underlying rationale extends well beyond the initial prokaryotic focus to all kingdoms of life and evolves into similar concepts for metagenomes, phenomes and epigenomes. The book's respective chapters address a range of topics, from the serendipitous emergence of the pan-genome concept and its impacts on the fields of microbiology, vaccinology and antimicrobial resistance, to the study of microbial communities, bioinformatic applications and mathematical models that tie in with complex systems and economic theory. Given its scope, the book will appeal to a broad readership interested in population dynamics, evolutionary biology and genomics. This work was published by Saint Philip Street Press pursuant to a Creative Commons license permitting commercial use. All rights not granted by the work's license are retained by the author or authors.
Author: Jeffrey Bennetzen
Publisher: Springer
ISBN: 3319974270
Category : Science
Languages : en
Pages : 390
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Book Description
This book discusses advances in our understanding of the structure and function of the maize genome since publication of the original B73 reference genome in 2009, and the progress in translating this knowledge into basic biology and trait improvement. Maize is an extremely important crop, providing a large proportion of the world’s human caloric intake and animal feed, and serving as a model species for basic and applied research. The exceptionally high level of genetic diversity within maize presents opportunities and challenges in all aspects of maize genetics, from sequencing and genotyping to linking genotypes to phenotypes. Topics covered in this timely book range from (i) genome sequencing and genotyping techniques, (ii) genome features such as centromeres and epigenetic regulation, (iii) tools and resources available for trait genomics, to (iv) applications of allele mining and genomics-assisted breeding. This book is a valuable resource for researchers and students interested in maize genetics and genomics.
Author: Andrew H. Paterson
Publisher: Springer Science & Business Media
ISBN: 1441959475
Category : Science
Languages : en
Pages : 562
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Book Description
The Saccharinae clade of the Poaceae (grass) family of flowering plants includes several important crops with a rich history of contributions to humanity and the promise of still-greater contributions, as a result of some of the highest biomass productivity levels known, resilience to drought and other environmental challenges that are likely to increase, amenability to production systems that may mitigate or even reverse losses of ecological capital such as topsoil erosion, and the recent blossoming of sorghum as a botanical and genomic model for the clade. In Genomics of the Saccharinae, advances of the past decade and earlier are summarized and synthesized to elucidate the current state of knowledge of the structure, function, and evolution of the Sorghum, Saccharum, and Miscanthus genera, and progress in the application of this knowledge to crop improvement. As a backdrop, it is important to understand the naturally occurring diversity in each genus, its organization and distribution, and its evolutionary history. Genomic tools and methods for Saccharinae biology and improvement have improved dramatically in the past few years – a detailed summary of these tools and their applications is a central element of this book. Application of genomic tools to priorities in crop improvement, including understanding and manipulating plant growth and development, composition, and defense, as well as increasing the quality and productivity of seed/grain, sugar, biomass, and other value-added products under a range of conditions and inputs, are addressed. In particular, as the first native African crop to emerge as a genomic model, sorghum offers an excellent case study of challenges and opportunities in linking new advances in biosciences to solving some of Africa’s major agricultural problems. Several members of the clade, exemplified by Sorghum halepense (Johnsongrass) offer insights into weediness and invasion biology. The first sequence for a member of the clade, sorghum, as well as progress and challenges toward sequencing of additional members and the new opportunities that this will create, are also explored. Indeed, the very complexities that have hindered study of some clade members also offer intriguing opportunities to gain insight into fundamental questions such as roles of polyploidy in agricultural productivity and post-polyploidy evolution.
Author: Veli Mäkinen
Publisher: Cambridge University Press
ISBN: 1009341219
Category : Computers
Languages : en
Pages : 470
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Book Description
Guided by standard bioscience workflows in high-throughput sequencing analysis, this book for graduate students, researchers, and professionals in bioinformatics and computer science offers a unified presentation of genome-scale algorithms. This new edition covers the use of minimizers and other advanced data structures in pangenomics approaches.
Author: João Carlos Setubal
Publisher: Springer Nature
ISBN: 1071638386
Category :
Languages : en
Pages : 622
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Book Description
Author: Edouard Jurkevitch
Publisher: Springer Nature
ISBN: 3030455998
Category : Science
Languages : en
Pages : 203
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Book Description
The book will provide an update on our understanding of predator-prey through the prism of ecology, physiology, molecular biology, and mathematical modelling. The integration of these different perspectives while focusing on the microbial realm will highlight the importance of scale in ecological interactions, and their importance in applications. This book should thereby contribute to theoretical as well as to applied ecologists and microbiologists. Furthermore, the detailed but amenable chapters could serve as the basis of teaching advanced courses in (microbial) ecology and environmental microbiology.This work is a collection of articles that discuss microbial predation from a variety of perspectives. It provides the readers a concise resource describing factors that are critical for several different predatory microbes, including Myxobacterium spp. and Bdellovibrio-and-like organisms (BALOs), including the mechanisms involved, ecological conditions that adversely impact it and potential applications in aquaculture and bioproduction. The first half of this collection focuses more on ecological aspects of predation, with in-depth discussions on “wolf pack” predators, the presence and activities of predators in waste-water treatment plants and the role of intraguild predatory relationships, i.e., when two different predators are competing for a single prey but also interact with one another. The reader will gain a deeper understanding of the predatory mechanisms involved and their ecological roles. In the latter half, emphasis is given more to the application and limitations of predators. In addition to discussing secondary metabolite production within different microbial predators, the readers will also learn how predators are being used to purify secondary metabolites from prey. This section also discusses the expanding and promising role of predation in aquaculture, focusing on the application of predators to reduce pathogenic populations, but includes some important caveats for young researchers to consider and follow when working with Bdellovibrio. This work is written for both experienced researchers already in the field and for young scientists who are captivated by the thought of predation at the microscale and its growing importance within a wide-array of fields.
