ÒSynthesis, Characterization and Antimicrobial Studies of Some Heterocyclic Compounds and Its Metal ComplexesÓ PDF Download
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Author: Dr. Sunita Baburao Garud
Publisher: Lulu.com
ISBN: 1365631494
Category : Education
Languages : en
Pages : 152
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Book Description
The development of modern medicinal inorganic chemistry, stimulated by the discovery of cis-dichlorodamine platinum (II) cis-platin & its subsequent use as a drug in the treatment of several human tumers has been fascinated by inorganic chemistry extensive knowledge of the coordination and redox properties of metal ions. Metal centres, being positively charge & Lewis acid, reformed to binds to negatively charged Biomolecules and the constituents of halogens, organic molecules especially heterocyclic compounds, proteins and nucleic acid offer excellent ligands for building of metal ions.
Author: Dr. Sunita Baburao Garud
Publisher: Lulu.com
ISBN: 1365631494
Category : Education
Languages : en
Pages : 152
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Book Description
The development of modern medicinal inorganic chemistry, stimulated by the discovery of cis-dichlorodamine platinum (II) cis-platin & its subsequent use as a drug in the treatment of several human tumers has been fascinated by inorganic chemistry extensive knowledge of the coordination and redox properties of metal ions. Metal centres, being positively charge & Lewis acid, reformed to binds to negatively charged Biomolecules and the constituents of halogens, organic molecules especially heterocyclic compounds, proteins and nucleic acid offer excellent ligands for building of metal ions.
Author: Magdalena Karolina Buczkowska
Publisher:
ISBN:
Category :
Languages : en
Pages : 0
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Book Description
Author: Ravindra S. Shinde
Publisher: CRC Press
ISBN: 1000029190
Category : Medical
Languages : en
Pages : 226
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Book Description
This book covers the general properties of heterocyclic compounds and methods for their preparation to use in applications of green chemistry. Heterocyclic compounds are an important class of molecules in organic chemistry due to their presence in natural products and their use in pharmaceuticals and new materials. They also play a vital role in the metabolism of living cells. Heterocyclic compounds have a wide range of applications in agrochemicals, pharmaceuticals, veterinary products, etc. This research-oriented volume is ideal for readers who want to fully realize the almost limitless potential of heterocyclic compounds and to discover new and effective pharmaceuticals among heterocyclic compounds, the largest and most varied family of organic compounds. The book features several case studies and step-by-step descriptions of synthetic methods and practical techniques. It also serves as a guide for chemists, offering them new insights and new paths to explore for effective drug discovery.
Author: Sreedhar Kumar Vellas
Publisher:
ISBN:
Category :
Languages : en
Pages : 374
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Book Description
The rapid emergence of drug resistant bacterial strains poses serious challenges to human society. The increased mortality rates caused by drug resistant bacterial infections and the depleted rate of new antibacterial drugs indicates a pressing need to focus on feasible therapeutic alternatives to counter this problem. Metal complexes offer a different steric and electronic profile which could be useful in the generation of new and effective antibacterial agents. Additionally, the unique metal specific mode of action of metal based antimicrobial agents makes them less prone to bacterial resistance and encourages the development of these complexes as clinically relevant antibacterial agents. The work presented in this thesis was undertaken with the aim of developing functionalized metal complexes using the "click" chemistry approach, with a view towards investigating the application of these complexes as potential antimicrobial agents.
Author: B.I. Kharisov
Publisher: Elsevier
ISBN: 0128110627
Category : Science
Languages : en
Pages : 470
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Book Description
Direct Synthesis of Metal Complexes provides in-depth coverage of the direct synthesis of coordination and organometallic compounds. The work is primarily organized by methods, but also covers highly relevant complexes, such as metal-polymer coordination compounds. This updated reference discusses recent developments in cryosynthesis, electrosynthesis, and tribosynthesis (popular as it doesn't require organic solvents), with special attention paid to 'greener' methodologies and approaches. Additionally, the book describes physical methods of zero-valent metal interaction with organic matter, including sputtering, ultrasonic treatment and synthesis in ionic liquids. The book presents completely new content as a follow-up to the 1999 Elsevier Science publication Direct Synthesis of Coordination and Organometallic Compounds that was edited by Dr. Garnovskii and Dr. Kharisov. - Covers current methods and techniques of metal interactions with organic media leading to metal chelates, adducts, di- and polymetallic complexes, metal-containing macrocycles, supported coordination compounds (i.e., metal complexes on carbon nanotubes), and more - Describes reactivities of distinct forms of elemental metals (powders, sheets, nanoparticles (including a host of less-common metal nanostructures) with organic phase (liquid, solid and gaseous) and water - Includes experimental procedures, with examples of direct synthesis, at the end of each chapter
Author: A. B. P. Lever
Publisher:
ISBN: 9780444416995
Category :
Languages : en
Pages : 0
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Book Description
Author: World Health Organization
Publisher: World Health Organization
ISBN: 9241565055
Category : Medical
Languages : en
Pages : 204
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Book Description
Chapter 1. Introduction -- chapter 2. Disease burden and 2015 targets assessment -- chapter 3. TB case notifications and treatment outcomes -- chapter 4. Drug-resistant TB -- chapter 5. Diagnostics and laboratory strengthening -- chapter 6. Addressing the co-epidemics of TB and HIV -- chapter 7. Financing -- chapter 8. Research and development -- Annexes.
Author: Geoffrey Wilkinson
Publisher:
ISBN:
Category : Coordination compounds
Languages : en
Pages : 1428
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Book Description
Author: T. Saroja
Publisher: Independent Author
ISBN: 9781805307389
Category : Education
Languages : en
Pages : 0
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Book Description
Metal Complexes of 2-Hydroxychalcones" is a comprehensive book authored by T. Saroja that focuses on the synthesis, characterization, and antimicrobial studies of metal complexes of 2-hydroxychalcones. The book explores the potential of these metal complexes as effective antimicrobial agents, and their use in the development of new drugs to combat bacterial and fungal infections. Saroja delves into the methods and techniques involved in the synthesis of these metal complexes, including the use of various metal ions and chelating ligands. She also explores the characterization of these complexes, including their structural properties, stability, and reactivity. The book highlights the antimicrobial properties of these metal complexes, including their activity against a range of bacterial and fungal strains. Saroja also discusses the potential mechanisms by which these complexes exert their antimicrobial effects, including disruption of cellular membranes and inhibition of enzymatic activity. Overall, "Metal Complexes of 2-Hydroxychalcones" is an essential reference for researchers, clinicians, and students working in the fields of medicinal chemistry, pharmacology, and microbiology. It provides a comprehensive overview of the synthesis, characterization, and antimicrobial properties of metal complexes of 2-hydroxychalcones, and highlights their potential as effective drugs for the treatment of microbial infections.
Author: Delong Zhang
Publisher:
ISBN:
Category :
Languages : en
Pages : 606
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Book Description
