Osteoarthritis, Inflammation and Degradation

Osteoarthritis, Inflammation and Degradation PDF Author: Joseph A. Buckwalter
Publisher: IOS Press
ISBN: 1586037730
Category : Health & Fitness
Languages : en
Pages : 316

Get Book Here

Book Description
Osteoarthritis is a public health issue due to its impact in term of handicap. Regarded as a multi-factorial disease, mechanistic and inflammatory theories are no more opposed but, on the contrary, are framed within the same continuum: osteoarthritis, inflammation and degeneration. This book helps readers understand the secrets of this disease.

Osteoarthritis, Inflammation and Degradation

Osteoarthritis, Inflammation and Degradation PDF Author: Joseph A. Buckwalter
Publisher: IOS Press
ISBN: 1586037730
Category : Health & Fitness
Languages : en
Pages : 316

Get Book Here

Book Description
Osteoarthritis is a public health issue due to its impact in term of handicap. Regarded as a multi-factorial disease, mechanistic and inflammatory theories are no more opposed but, on the contrary, are framed within the same continuum: osteoarthritis, inflammation and degeneration. This book helps readers understand the secrets of this disease.

State of the Art Imaging of Osteoarthritis

State of the Art Imaging of Osteoarthritis PDF Author: Ali Guermazi
Publisher: Clinics: Internal Medicine
ISBN: 9781437717501
Category : Medical
Languages : en
Pages : 0

Get Book Here

Book Description
This issue takes a multimodality approach to imaging of osteoarthritis. Clinical issues including an overview of the disease and imaging as an aid to evaluate patient functionality are also reviewed. Not only are current standards for imaging covered, but also newer techniques under development.

Pain in Osteoarthritis

Pain in Osteoarthritis PDF Author: David T. Felson
Publisher: John Wiley & Sons
ISBN: 9780470930557
Category : Medical
Languages : en
Pages : 320

Get Book Here

Book Description
An authoritative investigation of the sources andtreatment of osteoarthritic joint pain Millions of people throughout the world suffer from osteoarthritis (OA)—a medical condition causing its sufferers excruciating pain that is often disabling. This is the first book to offer clinicians an in-depth understanding of the biological sources of osteoarthritic pain and how they can be treated. Here, a team of leading international authorities has contributed state-of-the-art information on: The Neuroscience of Articular Pain—spinal and peripheral mechanisms of joint pain; experimental models for the study of osteoarthritic pain; inflammatory mediators and nociception in arthritis; phantoms in rheumatology; and more Osteoarthritis and Pain—joint mechanisms and neuromuscular aspects of OA; bone pain and pressure in OA joints; structural correlates of OA pain; and more Treatment of Osteoarthritic Pain—general approaches to treatment; treatments targeting pain receptors; treatments targeting biomechanical abnormalities; and treatments targeting inflammation Whether you're a medical professional, researcher, student, or a generalist or specialist focusing on pain or arthritis, this is your one-stop reference for understanding and treating joint pain in osteoarthritis.

Mayo Clinic on Arthritis

Mayo Clinic on Arthritis PDF Author: Gene G. Hunder
Publisher:
ISBN:
Category : Family & Relationships
Languages : en
Pages : 208

Get Book Here

Book Description
Covers the causes and symptoms of arthritis; offers tips on pain control, diet, and exercise; and describes such treatment options as medications, surgical procedures, and alternative therapies.

Mayo Clinic Internal Medicine Board Review Questions and Answers

Mayo Clinic Internal Medicine Board Review Questions and Answers PDF Author: Robert D. Ficalora
Publisher: Oxford University Press, USA
ISBN: 0199985871
Category : Medical
Languages : en
Pages : 164

Get Book Here

Book Description
Companion volume to: Mayo Clinic internal medicine board review. 10th ed. c2013.

Mesenchymal Stem Cell Therapy

Mesenchymal Stem Cell Therapy PDF Author: Lucas G. Chase
Publisher: Springer Science & Business Media
ISBN: 1627032002
Category : Science
Languages : en
Pages : 458

Get Book Here

Book Description
Over the past decade, significant efforts have been made to develop stem cell-based therapies for difficult to treat diseases. Multipotent mesenchymal stromal cells, also referred to as mesenchymal stem cells (MSCs), appear to hold great promise in regards to a regenerative cell-based therapy for the treatment of these diseases. Currently, more than 200 clinical trials are underway worldwide exploring the use of MSCs for the treatment of a wide range of disorders including bone, cartilage and tendon damage, myocardial infarction, graft-versus-host disease, Crohn’s disease, diabetes, multiple sclerosis, critical limb ischemia and many others. MSCs were first identified by Friendenstein and colleagues as an adherent stromal cell population within the bone marrow with the ability to form clonogenic colonies in vitro. In regards to the basic biology associated with MSCs, there has been tremendous progress towards understanding this cell population’s phenotype and function from a range of tissue sources. Despite enormous progress and an overall increased understanding of MSCs at the molecular and cellular level, several critical questions remain to be answered in regards to the use of these cells in therapeutic applications. Clinically, both autologous and allogenic approaches for the transplantation of MSCs are being explored. Several of the processing steps needed for the clinical application of MSCs, including isolation from various tissues, scalable in vitro expansion, cell banking, dose preparation, quality control parameters, delivery methods and numerous others are being extensively studied. Despite a significant number of ongoing clinical trials, none of the current therapeutic approaches have, at this point, become a standard of care treatment. Although exceptionally promising, the clinical translation of MSC-based therapies is still a work in progress. The extensive number of ongoing clinical trials is expected to provide a clearer path forward for the realization and implementation of MSCs in regenerative medicine. Towards this end, reviews of current clinical trial results and discussions of relevant topics association with the clinical application of MSCs are compiled in this book from some of the leading researchers in this exciting and rapidly advancing field. Although not absolutely all-inclusive, we hope the chapters within this book can promote and enable a better understanding of the translation of MSCs from bench-to-bedside and inspire researchers to further explore this promising and quickly evolving field.

Oxford Textbook of Osteoarthritis and Crystal Arthropathy, Third Edition

Oxford Textbook of Osteoarthritis and Crystal Arthropathy, Third Edition PDF Author: Michael Doherty
Publisher: Oxford University Press
ISBN: 0199668841
Category : Medical
Languages : en
Pages : 529

Get Book Here

Book Description
A trustworthy clinical companion, the textbook offers best practice and management strategies for these common joint diseases. Formerly published as Osteoarthritis, the extensively revised third edition of the Oxford Textbook of Osteoarthritis and Crystal Arthropathy provides up-to-date and evidence-based guidance on how to assess, diagnose, and manage patients. A prestigious and international author team ensure information is expert and relevant-this is a practical tool for clinicians managing people with osteoarthritis, gout, and other crystal-associated arthritis. Confidently consider and chose the right blend of treatment for your patient, whether physical, pharmacological, surgical, or supportive. The Oxford Textbook of Osteoarthritis and Crystal Arthropathy provides full coverage of joint failure, and includes detailed sections on epidemiology, risk factors, clinical assessment, and investigations. This edition also now includes new sections on gout and other crystal arthropathies. Clinically relevant and easily understandable overviews of basic science, including pathology and pain physiology, along with critical appraisal of current guidelines, make this a highly valuable resource. Significant coverage is also given to patient education and the involvement of the patient in management planning. Also highly illustrated, the textbook is a strong reference tool with summary boxes and key points at the end of chapters making it easy to find information quickly and help you deliver the optimum patient outcome. The textbook equips rheumatologists and musculoskeletal health professionals with the knowledge to provide best possible patient care.

Osteoarthritis Biomarkers and Treatments

Osteoarthritis Biomarkers and Treatments PDF Author:
Publisher: BoD – Books on Demand
ISBN: 1789857376
Category : Medical
Languages : en
Pages : 116

Get Book Here

Book Description
This book presents exclusive and comprehensive insight into the detailed molecular mechanisms of osteoarthritis (OA) initiation, progression and current advancements in the field. Inputs from clinician scientists, research and expertise offer a complete explanation of the current understanding of the pathogenesis of OA and practice in imaging and treatments strategies. Contributions from leading scientists provide a detailed introduction in the use of biomarkers in clinical research as well as in clinical practice and OA diagnosis. This book further discusses the potential of regenerative therapies and recent advances in cardiovascular and functional capacity on patients with OA.

Arthritis in Black and White

Arthritis in Black and White PDF Author: Anne C. Brower
Publisher: W.B. Saunders Company
ISBN:
Category : Health & Fitness
Languages : en
Pages : 382

Get Book Here

Book Description
This edition of this popular book is a well-written and practical introduction to the radiographic diagnosis of articular disorders. Features numerous high-quality radiographs and a new chapter on the evaluation of the foot and ankle.

Conn's Current Therapy 2021, E-Book

Conn's Current Therapy 2021, E-Book PDF Author: Rick D. Kellerman
Publisher: Elsevier Health Sciences
ISBN: 0323790712
Category : Medical
Languages : en
Pages : 1539

Get Book Here

Book Description
Designed to suit a wide range of healthcare providers, including primary care, subspecialties, and allied health, Conn’s Current Therapy has been a trusted clinical resource for well over 70 years. The 2021 edition continues this tradition of excellence with current, evidence-based treatment information presented in a concise yet in-depth format. More than 300 topics have been carefully reviewed and updated to bring you state-of-the-art information in even the most rapidly changing areas of medicine. Offers personal approaches from recognized leaders in the field, covering common complaints, acute diseases, and chronic illnesses along with the most current evidence-based clinical management options. Follows a consistent, easy-to-use format throughout, with diagnosis, therapy, drug protocols, and treatment pearls presented in quick-reference boxes and tables for point-of-care answers to common clinical questions. Includes new and significantly revised chapters on COVID-19, Diabetes Mellitus in Adults, Chronic Leukemias, and Osteomyelitis. Incorporates more electronic links throughout the text that connect the reader to apps and clinical prediction tools that can easily be accessed in practice. Features thoroughly reviewed and updated information from many new authors who offer a fresh perspective and their unique personal experience and judgment. Provides current drug information thoroughly reviewed by PharmDs. Features nearly 300 images, including algorithms, anatomical illustrations, and photographs, that provide useful information for diagnosis.