Author: Prof. Min Shi
Publisher: John Wiley & Sons
ISBN: 3527807306
Category : Science
Languages : en
Pages : 604
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Book Description
A comprehensive resource to the development and recent progress of zwitterion-oriented cycloadditions promoted by organoamines, organophosphines, N-heterocyclic carbenes Organocatalytic Cycloadditions for Synthesis of Carbo- and Heterocycles offers a clear explanationto thedevelopment of and the information on the latest research pertaining to zwitterion-oriented cycloadditions promoted by organoamines, organophosphines, N-heterocyclic carbenes. The authors—noted experts in the field—include a comprehensive review to the investigations of the reaction mechanisms and explore the synthesis of different products from the same starting materials. Filled with illustrative examples and designed to be accessible, the text shows how to control the chemo-, regio- and stereoselectivity and explains the further design of novel cycloaddition reactions catalyzed by organoamines and organophosphines based on zwitterion-oriented synthetic strategy. This important text: Explains why the formation of carbo- and heterocycles is a key transformation in organic synthesis. Offers a clear description to the development of zwitterion-oriented cycloadditions promoted by organoamines, organophosphines, N-heterocyclic carbenes, and explores the latest research Contains the most current examples involving synthetic transformations of organocatalytic cycloadducts Includes contributions from noted experts in the field of organic synthesis Written for organic chemists, pharmaceutical chemists, chemists in industry, graduates, and librarians, Organocatalytic Cycloadditions for Synthesis of Carbo- and Heterocyclesis is the essential guide to the topic.
Author: Eric F.V. Scriven
Publisher: Academic Press
ISBN: 032390128X
Category : Science
Languages : en
Pages : 332
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Book Description
Advances in Heterocyclic Chemistry, Volume 136 is the latest release in this definitive series in the field of heterocyclic chemistry, one of great importance to organic chemists, polymer chemists, and many biological scientists. Because biology and organic chemistry increasingly intersect, the associated nomenclature is used more frequently in explanations. Written by established authorities in the field from around the world, this comprehensive review combines descriptive synthetic chemistry and mechanistic insight to yield an understanding of how chemistry drives the preparation and useful properties of heterocyclic compounds. - Considered the definitive serial in the field of heterocyclic chemistry - Serves as the go-to reference for organic chemists, polymer chemists and many biological scientists - Provides the latest comprehensive reviews written by established authorities in the field - Combines descriptive synthetic chemistry and mechanistic insights to enhance understanding on how chemistry drives the preparation and useful properties of heterocyclic compounds
Author: Akkattu T. Biju
Publisher: John Wiley & Sons
ISBN: 3527809058
Category : Science
Languages : en
Pages : 440
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Book Description
Summarizing the emerging field of N-heterocyclic carbenes used in organocatalysis, this is an excellent overview of the synthesis and applications of NHCs focusing on carbon-carbon and carbon-heteroatom bond formation. Alongside comprehensive coverage of the synthesis, characteristics and applications, this handbook and ready reference also includes chapters on NHCs for polymerization reactions and natural product synthesis.
Author: Kengadarane Anebouselvy
Publisher: Royal Society of Chemistry
ISBN: 1782620907
Category : Science
Languages : en
Pages : 220
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Book Description
In the last decade a new era in asymmetric catalysis has been realised by the discovery of L-proline induced chiral enamines from carbonyls. Inspired by this, researchers have developed many other primary catalytic species in situ, more recently secondary catalytic species such as aminals have been identified for use in asymmetric synthesis. High-yielding asymmetric synthesis of bioactive and natural products through mild catalysis is an efficient approach in reaction engineering. In the early days, synthetic chemists mainly focused on the synthesis of complex molecules, with less attention on the reaction efficiency and eco-friendly conditions. Recent investigations have been directed towards the development of atom economy, eco-friendly and enantioselective synthesis for more targeted and efficient synthesis. Building on the momentum of this rapidly expanding research area, Dienamine catalysis for organic synthesis will provide a comprehensive introduction, from the preformed species, in situ generation and onto their applications in the synthesis of bioactive molecules and natural products.
Author: Ana Maria Faisca Phillips
Publisher: John Wiley & Sons
ISBN: 1119708796
Category : Science
Languages : en
Pages : 1370
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Book Description
A comprehensive overview of synthetic strategies for nonaromatic nitrogen heterocycles Nitrogen heterocycles are extremely widely distributed in nature, as well as in synthetic substances found in pharmaceuticals, agrochemicals, and materials chemistry. With new structures and medicines that include these structures emerging yearly, and a vast new journal literature to describe them, anyone who wants to be effective in R&D needs to easily access a synthesis of the latest research. This state-of-the-art survey explores recent developments in the most widely used reactions, as well as completely new ones. Highlights the major modern synthetic methods known to obtain nonaromatic nitrogen heterocycles, and their practical applications Topics include enantioselective synthesis and catalysis, photocatalysis, biocatalysis, microwave-assisted synthesis, reactions of oximes and nitrones, and ionic liquids Discusses how to synthesize rings of specific sizes Covers sustainable synthetic approaches for obtaining salts Whether you are using nonaromatic nitrogen compounds as an academic researcher, a synthetic chemist in industry, or an advanced student, this book is an essential, up-to-date resource to support your work.
Author: Paolo Quadrelli
Publisher: Elsevier
ISBN: 0128152745
Category : Science
Languages : en
Pages : 354
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Book Description
Modern Applications of Cycloaddition Chemistry examines this area of organic chemistry, with special attention paid to cycloadditions in synthetic and mechanistic applications in modern organic chemistry. While many books dedicated to cycloaddition reactions deal with the synthesis of heterocycles, general applications, specific applications in natural product synthesis, and the use of a class of organic compounds, this work sheds new light on pericyclic reactions by demonstrating how these valuable tools elegantly solve synthetic and mechanistic problems. The work examines how pericyclic reactions have been extensively applied to different chemistry areas, such as chemical biology, biological processes, catalyzed cycloaddition reactions, and more. This work will be useful for organic chemists who deal with organic chemistry, medicinal chemistry, agrochemistry and material chemistry. - Provides details on the synthesis of antiviral and anticancer compounds, marking the key role of unconventional catalyzed cycloaddition reactions for preparing new derivatives in a unique reaction pathway that is scalable in industrial processes - Contains the most up-to-date review of the use of pericyclic reactions in drug delivery - Includes the enzyme-catalyzed processes involving cycloaddition reactions for different targets, demonstrating that cycloaddition is more common in nature than expected - Features new applications for cycloadditions in material chemistry and provides a general view of the most recent results in the area
Author: Francesco Fringuelli
Publisher: John Wiley & Sons
ISBN: 9780471803430
Category : Science
Languages : en
Pages : 364
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Book Description
70 Jahre Forschung an der Diels-Alder-Reaktion: Dieses Buch fasst die wichtigsten und beeindruckendsten Ergebnisse in einzigartiger Weise zusammen! Zunächst werden die Grundprinzipien der Reaktion klar und verständlich anhand übersichtlicher Graphiken erläutert. Spezielle Vorschriften und gegebenenfalls ihre industrielle Umsetzung werden anschließend erklärt. Einen Schwerpunkt bilden auch physikalische und katalytische Verfahren zur Steigerung der Selektivität der Reaktion. Cycloadditionen in konventionellen und unkonventionellen Medien werden vorgestellt. Mit über 1.000 Literaturverweisen!
Author: Gautam Patel
Publisher: Elsevier
ISBN: 0443223254
Category : Technology & Engineering
Languages : en
Pages : 660
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Book Description
Modern advances in organic synthesis require compouds having attractive properties with high percentage of yield. Spirooxindole examines the current state of the art, recent progress and new challenges associated with the development of spirooxindole derivatives for various medicinal applications. Owing to their exceptional properties, these compounds can be used in vaious fields, including chemical and pharma industries, and in clinical research. This book has chapters written by experts in several different areas. It serves as a useful reference book for scientists, industrial practitioners, graduate students, and other professionals in the field of hetrocyclic chemistry, medicinal chemistry, organic synthesis clinical research and chemical sciences.The growing interest among the academics and industrial researchers in the field of organic chemistry and medicinal chemistry is the driving force for the presentation of this edited book. - Consolidates information on each aspect of this novel compound and its applications in various fields, covering the entire spectrum of up-to-date literature citations, current market, and patents - Provides a comprehensive, in-depth description of spirooxindole derivatives as well as multipurpose scaffolds - Highlights green synthesis and nanocatalysis - Describes in-depth various medicinal applications - Covers both synthesis and applications
Author: Bimal Banik
Publisher: Elsevier
ISBN: 0128175923
Category : Science
Languages : en
Pages : 1044
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Book Description
Extensive experimentation and high failure rates are a well-recognised downside to the drug discovery process, with the resultant high levels of inefficiency and waste producing a negative environmental impact. Sustainable and Green Approaches in Medicinal Chemistry reveals how medicinal and green chemistry can work together to directly address this issue. After providing essential context to the growth of green chemistry in relation to drug discovery in Part 1, the book goes on to identify a broad range of practical methods and synthesis techniques in Part 2. Part 3 reveals how medicinal chemistry techniques can be used to improve efficiency, mitigate failure and increase the environmental benignity of the entire drug discovery process, whilst Parts 4 and 5 discuss natural products and microwave-induced chemistry. Finally, the role of computers in drug discovery is explored in Part 6.
Author: Peter I. Dalko
Publisher: John Wiley & Sons
ISBN: 3527658882
Category : Science
Languages : en
Pages : 1499
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Book Description
Structured in three parts this manual recollects efficient organocatalytic transformations around clear principles that meet actual standard in asymmetric synthesis. Chapters were written by acknowledged leaders of the organocatalysis field, and are presented in a concise way. Volume 1: Privileged Catalysts gives insight to readers to the continuously increasing variety of catalysts, and the relatively complex interactions that make organocatalytic reactions selective. An appendix recollects catalyst structures with the adequate cross-references. Volume 2: Activations covers the fundamental activation types (non-covalent and covalent activations) and helps understanding the importance of physical parameters, and in particular, the role of water, that influences reactivity and selectivity. Volume 3: Reactions and Applications highlights transformations by reaction types. The final part of this volume is dedicated to application in multistep synthesis and industrial applications. Considering the ever increasing interest in the organocatalysis field, the book aims addressing to a large audience: to academic, and, industrial researchers, students and teachers who are interested in synthetic organic chemistry at advanced level. This book provides non-specialists with an introduction to the topic as well as serving as a valuable source for newcomers and researchers searching for an up-to-date and comprehensive overview of this promising area of synthetic organic chemistry.
