Author: T.A. Sonia
Publisher: Elsevier
ISBN: 1908818689
Category : Medical
Languages : en
Pages : 361
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Book Description
Diabetes Mellitus, a syndrome of disordered metabolism, characterised by abnormal elevation in blood glucose level, has become a life-threatening condition for many people. Current means of therapy for Diabetes Mellitus do not mimic the normal physiological pattern of insulin release. Oral delivery is the preferred route of administration due to its non-invasive nature. Oral delivery of insulin presents an overview of Diabetes Mellitus, and discusses the strategies and techniques adopted for oral delivery of insulin. This title begins with an introductory chapter on symptoms, complications and therapy for Diabetes Mellitus. Subsequent chapters cover the various routes for administering insulin; the challenges and strategies of oral delivery; experimental techniques in the development of an oral insulin carrier; lipids; inorganic nanoparticles and polymers in oral insulin delivery; and a summary and presentation of future perspectives on oral delivery of insulin. Presents an overview of Diabetes Mellitus Includes a discussion of various strategies and techniques adopted for oral delivery of insulin Presents an update of research in the field
Author: Revanth Rayasam
Publisher:
ISBN:
Category :
Languages : en
Pages :
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Book Description
Author: Philip Cryer
Publisher: American Diabetes Association
ISBN: 1580406491
Category : Medical
Languages : en
Pages : 194
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Book Description
Intended for diabetes researchers and medical professionals who work closely with patients with diabetes, this newly updated and expanded edition provides new perspectives and direct insight into the causes and consequences of this serious medical condition from one of the foremost experts in the field. Using the latest scientific and medical developments and trends, readers will learn how to identify, prevent, and treat this challenging phenomenon within the parameters of the diabetes care regimen.
Author: Ashok K. Srivastava
Publisher: Springer Science & Business Media
ISBN: 9780792381136
Category : Science
Languages : en
Pages : 206
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Book Description
In 1996 the 75th anniversary of the discovery of insulin was celebrated at the University of Toronto, the scene of that discovery in 1921. This volume was stimulated by the scientific program which was staged at that time and brought together much of the world's best talent to discuss and analyze the most recent developments in our understanding of pancreatic function, insulin secretion, the interaction of insulin with its target tissues, the mechanism of insulin action at the cellular level, and the defects which underlie both Type I (insulin-dependent diabetes mellitus, IDDM) and Type II (noninsulin-dependent diabetes mellitus, NIDDM) forms of the disease. We have chosen to focus the present volume on work related to insulin action.
Author: William T. Cefalu
Publisher: CRC Press
ISBN: 0824744624
Category : Medical
Languages : en
Pages : 270
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Book Description
Provides how-to guidelines for inpatient and outpatient insulin therapy in children and adults and during pregnancy and in hyperglycemic emergencies. Evaluating strategies for the management of types 1 and 2 diabetes, this reference explores the pharmacokinetics of insulin and insulin programs as well as the latest glucose self-monitoring eq
Author: Masoud Rahman
Publisher: Springer Science & Business Media
ISBN: 3642375553
Category : Science
Languages : en
Pages : 95
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Book Description
In recent years, the fabrication of nanomaterials and exploration of their properties have attracted the attention of various scientific disciplines such as biology, physics, chemistry, and engineering. Although nanoparticulate systems are of significant interest in various scientific and technological areas, there is little known about the safety of these nanoscale objects. It has now been established that the surfaces of nanoparticles are immediately covered by biomolecules (e.g. proteins, ions, and enzymes) upon their entrance into a biological medium. This interaction with the biological medium modulates the surface of the nanoparticles, conferring a “biological identity” to their surfaces (referred to as a “corona”), which determines the subsequent cellular/tissue responses. The new interface between the nanoparticles and the biological medium/proteins, called “bio-nano interface,” has been very rarely studied in detail to date, though the interest in this topic is rapidly growing. In this book, the importance of the physiochemical characteristics of nanoparticles for the properties of the protein corona is discussed in detail, followed by comprehensive descriptions of the methods for assessing the protein-nanoparticle interactions. The advantages and limitations of available corona evaluation methods (e.g. spectroscopy methods, mass spectrometry, nuclear magnetic resonance, electron microscopy, X-ray crystallography, and differential centrifugal sedimentation) are examined in detail, followed by a discussion of the possibilities for enhancing the current methods and a call for new techniques. Moreover, the advantages and disadvantages of protein-nanoparticle interaction phenomena are explored and discussed, with a focus on the biological impacts.
Author: Amit Kumar Nayak
Publisher: Springer Nature
ISBN: 3030469239
Category : Technology & Engineering
Languages : en
Pages : 390
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Book Description
This book discusses the recent innovations in the development of various advanced biopolymeric systems, including gels, in situ gels, hydrogels, interpenetrating polymer networks (IPNs), polyelectrolyte complexes (PECs), graft co-polymers, stimuli-responsive polymers, polymeric nanoparticles, nanocomposites, polymeric micelles, dendrimers, liposomes and scaffolds. It also examines their applications in drug delivery.
Author: Sanjay Agarwal
Publisher: Jaypee Brothers Medical Publishers
ISBN: 9352706846
Category : Medical
Languages : en
Pages : 331
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Book Description
Author: John Baillieul
Publisher: Springer
ISBN: 9781447150572
Category : Technology & Engineering
Languages : en
Pages : 1554
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Book Description
The Encyclopedia of Systems and Control collects a broad range of short expository articles that describe the current state of the art in the central topics of control and systems engineering as well as in many of the related fields in which control is an enabling technology. The editors have assembled the most comprehensive reference possible, and this has been greatly facilitated by the publisher’s commitment continuously to publish updates to the articles as they become available in the future. Although control engineering is now a mature discipline, it remains an area in which there is a great deal of research activity, and as new developments in both theory and applications become available, they will be included in the online version of the encyclopedia. A carefully chosen team of leading authorities in the field has written the well over 250 articles that comprise the work. The topics range from basic principles of feedback in servomechanisms to advanced topics such as the control of Boolean networks and evolutionary game theory. Because the content has been selected to reflect both foundational importance as well as subjects that are of current interest to the research and practitioner communities, a broad readership that includes students, application engineers, and research scientists will find material that is of interest.
Author: Afrede Momina
Publisher: LAP Lambert Academic Publishing
ISBN: 9783659522987
Category :
Languages : en
Pages : 60
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Book Description
Noninvasive treatment alternatives for diseases from diabetes to hypercholerestemia are at the cutting edge of research. Although many noninvasive drug delivery routes, including oral, buccal, and dermal have been investigated no route has been fully approved for patient use by the Food and Drug Administration (FDA) standards as an alternative to current needle dependent insulin delivery. 10 12 This book focuses on two novel oral protein drug delivery systems -Zr(IV) phosphate ( -ZrP)-protein-Divalent Metal Ion and - Zr(IV) phosphate ( -ZrP)-protein- cationized Bovine Serum Albumin BSA. Glucose oxidase (GO) serves as a model protein in this book for noninvasive alternatives to lowering blood sugar in type I and II diabetics. However, instead of encapsulating GO, an oral drug treatment for diabetes, alternative proteins can also be encapsulated as oral drug treatments for ailments such as hypercholesterolemia. This experiment tests what ionized version of BSA (native BSA-TEPA (-25), BSA-TEPA (0), BSA-TEPA (-13), BSA-TEPA (+5), or divalent metal ion (Mg (II), Ca (II), or Ba (II)) intercalated into ZrP results in maximal GO binding and release in the intestinal region."
