Optical Interaction in Plasmonic Photothermal Therapeutics PDF Download
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Author: Vikas
Publisher: Mohammed Abdul Sattar
ISBN:
Category : Medical
Languages : en
Pages : 0
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Book Description
Cancer is a disease in which biological cells grow uncontrollably and spread to other organs of a patient. Cancer disease comprises of abnormal cells, which can develop in any part of the human body. Normally, cells grow and multiply in a controlled manner, and when these become old or damaged, then cells die i.e., known as programmed cell death or apoptosis. Sometimes this controlled process of cell growth or death breaks down and there is abnormal growth of cells which form tumors in the body. The tumor cells grow slowly and do not spread in the body are known as benign (noncancerous) tumors. When tumor cells grow rapidly, these spread throughout the body and are called malignant tumors (cancerous). While there is no one specific cause of cancer, factors such as smoking, excessive UV exposure from the sun or tanning beds, being overweight or obese, and excessive alcohol use can all contribute to the formation of cancerous cells in the body. A few emerging techniques such as immunotherapy, radio-frequency ablation, thermal ablation, cryotherapy, photodynamic therapy and plasmonic photothermal therapy, show higher efficacy and long survival rates as compared to the conventional methods. Nanoparticles (1-100 nm in size) offer a biocompatible and biodegradable platform for cancer diagnosis as a contrast agent and as a cancer treatment through nanoparticle based thermal ablation or delivery of conventional chemotherapeutic drugs. The light interaction of biological tissue provides a basis for a wide variety of biomedical applications, like non-invasive diagnosis (tumor detection, contrast microscopy, optical coherence tomography, etc.), treatment (laser surgery, photodynamic therapy, photothermal therapy, etc.), and monitoring of bio-parameters (pulse oximetry, glucose monitoring, etc.). The thermal ablation of the tumor by using light interaction of metallic nanoparticles is known as plasmonic photothermal interaction. This allows for tumor treatment with minimal side effects on nearby healthy tissue. This technique is critically governed by the optical characteristics of tissue as well as the variations in the properties during the interaction of light with the nanoparticles or tissue. For example, the efficacy of cancer treatment by plasmonic photothermal therapy mainly depends upon the light absorption by tumor cells and/or nanoparticles. Therefore, it is important to characterize the optical characteristics of tissue, especially in the presence of nanoparticles and at different stages of photothermal therapy for pre-treatment planning as well as improving the efficacy of the therapy.
Author: Vikas
Publisher: Mohammed Abdul Sattar
ISBN:
Category : Medical
Languages : en
Pages : 0
Get Book Here
Book Description
Cancer is a disease in which biological cells grow uncontrollably and spread to other organs of a patient. Cancer disease comprises of abnormal cells, which can develop in any part of the human body. Normally, cells grow and multiply in a controlled manner, and when these become old or damaged, then cells die i.e., known as programmed cell death or apoptosis. Sometimes this controlled process of cell growth or death breaks down and there is abnormal growth of cells which form tumors in the body. The tumor cells grow slowly and do not spread in the body are known as benign (noncancerous) tumors. When tumor cells grow rapidly, these spread throughout the body and are called malignant tumors (cancerous). While there is no one specific cause of cancer, factors such as smoking, excessive UV exposure from the sun or tanning beds, being overweight or obese, and excessive alcohol use can all contribute to the formation of cancerous cells in the body. A few emerging techniques such as immunotherapy, radio-frequency ablation, thermal ablation, cryotherapy, photodynamic therapy and plasmonic photothermal therapy, show higher efficacy and long survival rates as compared to the conventional methods. Nanoparticles (1-100 nm in size) offer a biocompatible and biodegradable platform for cancer diagnosis as a contrast agent and as a cancer treatment through nanoparticle based thermal ablation or delivery of conventional chemotherapeutic drugs. The light interaction of biological tissue provides a basis for a wide variety of biomedical applications, like non-invasive diagnosis (tumor detection, contrast microscopy, optical coherence tomography, etc.), treatment (laser surgery, photodynamic therapy, photothermal therapy, etc.), and monitoring of bio-parameters (pulse oximetry, glucose monitoring, etc.). The thermal ablation of the tumor by using light interaction of metallic nanoparticles is known as plasmonic photothermal interaction. This allows for tumor treatment with minimal side effects on nearby healthy tissue. This technique is critically governed by the optical characteristics of tissue as well as the variations in the properties during the interaction of light with the nanoparticles or tissue. For example, the efficacy of cancer treatment by plasmonic photothermal therapy mainly depends upon the light absorption by tumor cells and/or nanoparticles. Therefore, it is important to characterize the optical characteristics of tissue, especially in the presence of nanoparticles and at different stages of photothermal therapy for pre-treatment planning as well as improving the efficacy of the therapy.
Author: Guillaume Baffou
Publisher: Cambridge University Press
ISBN: 1108307868
Category : Science
Languages : en
Pages : 310
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Book Description
Plasmonics is an important branch of optics concerned with the interaction of metals with light. Under appropriate illumination, metal nanoparticles can exhibit enhanced light absorption, becoming nanosources of heat that can be precisely controlled. This book provides an overview of the exciting new field of thermoplasmonics and a detailed discussion of its theoretical underpinning in nanophotonics. This topic has developed rapidly in the last decade, and is now a highly-active area of research due to countless applications in nanoengineering and nanomedicine. These important applications include photothermal cancer therapy, drug and gene delivery, nanochemistry and photothermal imaging. This timely and self-contained text is suited to all researchers and graduate students working in plasmonics, nano-optics and thermal-induced processes at the nanoscale.
Author: Yi-Tao Long
Publisher: Springer Science & Business Media
ISBN: 3642547958
Category : Science
Languages : en
Pages : 123
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Book Description
This book introduces the fundamentals and applications of the localized surface plasmon resonance (LSPR) property of noble metallic nanoparticles, with an emphasis on the biosensing applications of plasmonic nanoparticles, especially in living cell imaging and photothermal therapy. It provides an overview of the different operating principles of plasmonic sensors, particularly the single-nanoparticle-based detections, and a series of creative biosensors based on the modulation of different parameters of nanoparticles (particle size, shape, composition and surrounding medium) for label-free detection. The interparticle coupling effect, plasmon resonance energy transfer, electron transfer on plasmonics surface are also covered in this book. This book is intended for graduate students and researchers working in the interdisciplinary field combining chemistry, biology, material science and nanophotonics. Yi-Tao Long is a Professor at the School of Chemistry and Molecular Engineering, East China University of Science and Technology, China.
Author: Enyi Ye
Publisher: Royal Society of Chemistry
ISBN: 1839165189
Category : Science
Languages : en
Pages : 359
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Book Description
The exploration of photothermal nanomaterials with high light-to-heat conversion efficiency has paved the way for practical applications, including in cancer therapy, environmental remediation, catalysis, imaging and biomedicine. Covering the photothermal effect of different categories of light-absorbing nanomaterials, and focusing on metallic nanomaterials, 2D materials, semiconductors, carbon-based nanomaterials, polymeric nanomaterials and their composites, chapters in this book provide a systematic summary of recent advances in the fabrication and application of photothermal nanomaterials, discussing advantages, challenges and potential opportunities. This text will be a valuable resource for scientists working on photothermal nanomaterials, as well as those interested in the applications across chemistry, biomedicine, nanotechnology and materials science.
Author: Mingson Wang (Ph. D.)
Publisher:
ISBN:
Category :
Languages : en
Pages : 346
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Book Description
Advances in nanofabrication and characterization of nanomaterials enable the development of plasmonic nanostructures with unique optical properties. Plasmonic nanostructures have been extensively studied for their potential applications in optical sensing, photothermal therapy, photovoltaics, and photocatalysis. In this dissertation, we present studies of light-matter interactions in hybrid systems consisting of plasmonic nanostructures and functional materials. These studies are focused on four major types of light-matter interactions in plasmonic nanostructures: (1) plasmon-induced resonance energy transfer (PIRET); (2) plasmon-enhanced spontaneous emission; (3) Fano interference between plasmonic nanostructures and emitters; and (4) strong plasmon-exciton coupling. We also achieved the tuning of light-matter interactions by modifying the physical properties of functional materials or plasmonic nanostructures. In addition, the active control of light-matter interactions was demonstrated by integrating plasmonic nanostructures with switchable materials, such as photochromic dyes. Specifically, we first demonstrated the blue-shifted PIRET from a single gold nanorod (AuNR) to dye molecules. AuNRs enable the energy transfer from plasmonic donors to dye acceptors with light having a longer wavelength and lower intensity, compared to dye donors. Secondly, we studied the tuning of plasmon-trion and plasmon-exciton resonance energy transfer from a single gold nanotriangle (AuNT) to monolayer MoS2. We achieved these phenomena by the combination of rationally designed monolayer MoS2-plasmonic nanoparticle hybrid systems and single-nanoparticle measurements. Thirdly, we realized the large modulation of hybrid plasmonic waveguide mode (HPWM) in single hybrid molecule-plasmon nanostructures through the strong molecule-plasmon coupling. The HPWM features both the capacity of plasmonic nanostructures to manipulate light at the nanoscale and the low loss of dielectric waveguides. Fourthly, we demonstrated the photoswitchable plasmon-induced fluorescence enhancement. This large switchable modulation of fluorescence was derived from the large near-field enhancement at the subnanometer gap between Au nanoparticles and switchable intersystem crossing as a nonradiative decay channel in photochromic dyes. Finally, we achieved tunable Fano resonances and plasmon-exciton coupling in two-dimensional (2D) WS2-AuNT hybrid structures at room temperature. The tuning of Fano resonances and plasmon-exciton coupling were achieved by the active control of the WS2 exciton binding energy and dipole-dipole interaction through controlling the dielectric constant of the surrounding medium.
Author: Tuan Vo-Dinh
Publisher: CRC Press
ISBN: 1420085174
Category : Medical
Languages : en
Pages : 767
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Book Description
Shaped by Quantum Theory, Technology, and the Genomics RevolutionThe integration of photonics, electronics, biomaterials, and nanotechnology holds great promise for the future of medicine. This topic has recently experienced an explosive growth due to the noninvasive or minimally invasive nature and the cost-effectiveness of photonic modalities in
Author: Peng Yu
Publisher: Springer Nature
ISBN: 303087544X
Category : Science
Languages : en
Pages : 348
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Book Description
This book highlights cutting-edge research in surface plasmons, discussing the different types and providing a comprehensive overview of their applications. Surface plasmons (SPs) receive special attention in nanoscience and nanotechnology due to their unique optical, electrical, magnetic, and catalytic properties when operating at the nanoscale. The excitation of SPs in metal nanostructures enables the manipulation of light beyond the diffraction limit, which can be utilized for enhancing and tailoring light-matter interactions and developing ultra-compact high-performance nanophotonic devices for various applications. With clear and understandable illustrations, tables, and descriptions, this book provides physicists, materials scientists, chemists, engineers, and their students with a fundamental understanding of surface plasmons and device applications as a basis for future developments.
Author: V. Ramamurthy
Publisher: CRC Press
ISBN: 9780824701741
Category : Science
Languages : en
Pages : 378
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Book Description
Focusing on complex naturally-occurring and synthetic supramolecular arrays, this work describes the mechanism by which transition metal complexes bind to DNA and how the DNA scaffold modifies the photochemical and photophysical properties to bound complexes. It includes details of photoinduced electron transfer between intercalated molecules, and examines thermally and photochemically induced electron transfer in supramolecular assemblies consisting of inorganic molecular building blocks.
Author: Divya Khurana
Publisher: Springer Nature
ISBN: 9819998794
Category : Cancer
Languages : en
Pages : 185
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Book Description
Zusammenfassung: This book describes the plasmonic photothermal-assisted multimodal cancer therapeutics in the area of cancer nanotechnology or cancer nanomedicine. This book covers the fundamentals of plasmonic photothermal cancer therapy as well as plasmonic photothermal mediated multimodal cancer therapy. The various steps involved in developing such therapeutic modality, viz. (a) the selection of suitable nanoparticles, (b) synthesis of multifunctional nanocomposite, (c) optimization of the photosensitizer and chemotherapeutic drug loadings, (d) characterization of the synthesized nanocomposite, and (e) therapeutic evaluations through novel tumor-tissue mimicking phantoms and the cancer cell lines are discussed in detail. Apart from the detailed description of therapeutic outcome, this book provides a step-by-step approach to develop a multifunctional nanocomposite for such therapeutics. Overall, this book provides simplified and in-depth information about cancer nanobiotechnology to the researchers and graduate students in subject areas of nanotechnology, biotechnology and pharmaceutics to develop and contribute to such multimodal cancer therapeutics
Author: Faheem Arjamend Sheikh
Publisher: Springer Nature
ISBN: 9819921198
Category : Science
Languages : en
Pages : 936
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Book Description
This book examines the interactions of nanomaterials with the biological system. The chapters of the book explore the natural and synthetic biomaterials that modulate immune responses for their applications in drug delivery and tissue engineering. Further, the book discusses the implications of the physiochemical properties of nanoparticles and their microenvironment on their interactions with biological systems. The chapters also present the recognitive capabilities of biomaterials for the development of novel strategies for the detection and treatment of autoimmune disorders. The book also introduces nanotechnology platforms for drug delivery and highlights current and emerging nanotechnologies that could enable novel classes of therapeutics. Towards the end, the book reviews the efficiency of drug-loaded nanoparticles in modulating the functioning of the biological milieu for improved disease treatment. Lastly, the book outlines the ethical issues regarding the use of nanoparticles for in vitro and in vivo applications. Given its scope, it is a valuable resource for graduate students and researchers interested in understanding the biomedical applications of nanoparticles and their interactions with the biological milieu.
