The Gene Ontology Handbook

The Gene Ontology Handbook PDF Author: Christophe Dessimoz
Publisher:
ISBN: 9781013267710
Category : Science
Languages : en
Pages : 298

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Book Description
This book provides a practical and self-contained overview of the Gene Ontology (GO), the leading project to organize biological knowledge on genes and their products across genomic resources. Written for biologists and bioinformaticians, it covers the state-of-the-art of how GO annotations are made, how they are evaluated, and what sort of analyses can and cannot be done with the GO. In the spirit of the Methods in Molecular Biology book series, there is an emphasis throughout the chapters on providing practical guidance and troubleshooting advice. Authoritative and accessible, The Gene Ontology Handbook serves non-experts as well as seasoned GO users as a thorough guide to this powerful knowledge system. This work was published by Saint Philip Street Press pursuant to a Creative Commons license permitting commercial use. All rights not granted by the work's license are retained by the author or authors.

The Gene Ontology Handbook

The Gene Ontology Handbook PDF Author: Christophe Dessimoz
Publisher:
ISBN: 9781013267710
Category : Science
Languages : en
Pages : 298

Get Book Here

Book Description
This book provides a practical and self-contained overview of the Gene Ontology (GO), the leading project to organize biological knowledge on genes and their products across genomic resources. Written for biologists and bioinformaticians, it covers the state-of-the-art of how GO annotations are made, how they are evaluated, and what sort of analyses can and cannot be done with the GO. In the spirit of the Methods in Molecular Biology book series, there is an emphasis throughout the chapters on providing practical guidance and troubleshooting advice. Authoritative and accessible, The Gene Ontology Handbook serves non-experts as well as seasoned GO users as a thorough guide to this powerful knowledge system. This work was published by Saint Philip Street Press pursuant to a Creative Commons license permitting commercial use. All rights not granted by the work's license are retained by the author or authors.

Semantic Similarity from Natural Language and Ontology Analysis

Semantic Similarity from Natural Language and Ontology Analysis PDF Author: Sébastien Harispe
Publisher: Springer Nature
ISBN: 3031021568
Category : Computers
Languages : en
Pages : 245

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Book Description
Artificial Intelligence federates numerous scientific fields in the aim of developing machines able to assist human operators performing complex treatments---most of which demand high cognitive skills (e.g. learning or decision processes). Central to this quest is to give machines the ability to estimate the likeness or similarity between things in the way human beings estimate the similarity between stimuli. In this context, this book focuses on semantic measures: approaches designed for comparing semantic entities such as units of language, e.g. words, sentences, or concepts and instances defined into knowledge bases. The aim of these measures is to assess the similarity or relatedness of such semantic entities by taking into account their semantics, i.e. their meaning---intuitively, the words tea and coffee, which both refer to stimulating beverage, will be estimated to be more semantically similar than the words toffee (confection) and coffee, despite that the last pair has a higher syntactic similarity. The two state-of-the-art approaches for estimating and quantifying semantic similarities/relatedness of semantic entities are presented in detail: the first one relies on corpora analysis and is based on Natural Language Processing techniques and semantic models while the second is based on more or less formal, computer-readable and workable forms of knowledge such as semantic networks, thesauri or ontologies. Semantic measures are widely used today to compare units of language, concepts, instances or even resources indexed by them (e.g., documents, genes). They are central elements of a large variety of Natural Language Processing applications and knowledge-based treatments, and have therefore naturally been subject to intensive and interdisciplinary research efforts during last decades. Beyond a simple inventory and categorization of existing measures, the aim of this monograph is to convey novices as well as researchers of these domains toward a better understanding of semantic similarity estimation and more generally semantic measures. To this end, we propose an in-depth characterization of existing proposals by discussing their features, the assumptions on which they are based and empirical results regarding their performance in particular applications. By answering these questions and by providing a detailed discussion on the foundations of semantic measures, our aim is to give the reader key knowledge required to: (i) select the more relevant methods according to a particular usage context, (ii) understand the challenges offered to this field of study, (iii) distinguish room of improvements for state-of-the-art approaches and (iv) stimulate creativity toward the development of new approaches. In this aim, several definitions, theoretical and practical details, as well as concrete applications are presented.

Business Systems Analysis with Ontologies

Business Systems Analysis with Ontologies PDF Author: Green, Peter F.
Publisher: IGI Global
ISBN: 1591403413
Category : Computers
Languages : en
Pages : 378

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Book Description
"This book shows systems analysts and business analysts how ontological thinking can help them clarify requirements analysis tasks in business systems"--Provided by publisher.

Ontology Made Easy

Ontology Made Easy PDF Author: Amie Lynn Thomasson
Publisher: Oxford University Press, USA
ISBN: 0199385114
Category : Philosophy
Languages : en
Pages : 361

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Book Description
Existence questions have been topics for heated debates in metaphysics, but this book argues that they can often be answered easily, by trivial inferences from uncontroversial premises. This 'easy' approach to ontology leads to realism about disputed entities, and to the view that metaphysical disputes about existence questions are misguided.

Bioinformatics in Aquaculture

Bioinformatics in Aquaculture PDF Author: Zhanjiang (John) Liu
Publisher: John Wiley & Sons
ISBN: 1118782356
Category : Science
Languages : en
Pages : 605

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Book Description
Bioinformatics derives knowledge from computer analysis of biological data. In particular, genomic and transcriptomic datasets are processed, analysed and, whenever possible, associated with experimental results from various sources, to draw structural, organizational, and functional information relevant to biology. Research in bioinformatics includes method development for storage, retrieval, and analysis of the data. Bioinformatics in Aquaculture provides the most up to date reviews of next generation sequencing technologies, their applications in aquaculture, and principles and methodologies for the analysis of genomic and transcriptomic large datasets using bioinformatic methods, algorithm, and databases. The book is unique in providing guidance for the best software packages suitable for various analysis, providing detailed examples of using bioinformatic software and command lines in the context of real world experiments. This book is a vital tool for all those working in genomics, molecular biology, biochemistry and genetics related to aquaculture, and computational and biological sciences.

Martin Buber's Ontology

Martin Buber's Ontology PDF Author: Robert E. Wood
Publisher: Northwestern University Press
ISBN: 9780810106505
Category : Philosophy
Languages : en
Pages : 162

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Book Description
Describes the origins, structure, and meaning of the leading philosophic work by the Jewish religious scholar.

Ontology-Based Information Retrieval for Healthcare Systems

Ontology-Based Information Retrieval for Healthcare Systems PDF Author: Vishal Jain
Publisher: John Wiley & Sons
ISBN: 1119641381
Category : Computers
Languages : en
Pages : 384

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Book Description
With the advancements of semantic web, ontology has become the crucial mechanism for representing concepts in various domains. For research and dispersal of customized healthcare services, a major challenge is to efficiently retrieve and analyze individual patient data from a large volume of heterogeneous data over a long time span. This requirement demands effective ontology-based information retrieval approaches for clinical information systems so that the pertinent information can be mined from large amount of distributed data. This unique and groundbreaking book highlights the key advances in ontology-based information retrieval techniques being applied in the healthcare domain and covers the following areas: Semantic data integration in e-health care systems Keyword-based medical information retrieval Ontology-based query retrieval support for e-health implementation Ontologies as a database management system technology for medical information retrieval Information integration using contextual knowledge and ontology merging Collaborative ontology-based information indexing and retrieval in health informatics An ontology-based text mining framework for vulnerability assessment in health and social care An ontology-based multi-agent system for matchmaking patient healthcare monitoring A multi-agent system for querying heterogeneous data sources with ontologies for reducing cost of customized healthcare systems A methodology for ontology based multi agent systems development Ontology based systems for clinical systems: validity, ethics and regulation

Measuring and Analysing the Use of Ontologies

Measuring and Analysing the Use of Ontologies PDF Author: Jamshaid Ashraf
Publisher: Springer
ISBN: 3319756818
Category : Technology & Engineering
Languages : en
Pages : 309

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Book Description
This unique book succinctly summarizes the need to measure how ontologies (one of the building blocks of the Semantic Web) are currently being utilized, providing insights for various stakeholders. Where possible it improves and reuses terms in existing vocabularies/ontologies, as recommended by the Linked Data community. Recent advances in the Semantic Web have led to a proliferation of Resource Description Framework (RDF) data, which employ ontologies to semantically describe the information on the Web making it equally understandable for both humans and machines. However, to create a network effect, it is important that selective ontologies are used by more data publishers to improve the value of that ontology. For this to happen, it is vital to discover what is being used from an ontology to semantically annotate the information on the Web specific to a given domain. Answers to such basic but crucial questions can only be achieved by ascertaining how ontologies in the current semantic web are being utilized and adopted. The proposed frameworks to obtain such insights are explained with real-world examples to provide a clear and detailed description of ontology usage analysis. Both theoretical and practical, the book is of value to academics and professionals working in industry. Specifically, it is of primary interest to researchers, graduate students and practitioners in the area of the Semantic Web and its various real-world applications.

Existence

Existence PDF Author: Peter van Inwagen
Publisher: Cambridge University Press
ISBN: 1107047129
Category : Literary Collections
Languages : en
Pages : 271

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Book Description
This is a collection of Peter van Inwagen's recent essays on ontology and meta-ontology.

Domain Analysis for Knowledge Organization

Domain Analysis for Knowledge Organization PDF Author: Richard Smiraglia
Publisher: Chandos Publishing
ISBN: 0081001886
Category : Business & Economics
Languages : en
Pages : 116

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Book Description
Domain analysis is the process of studying the actions, knowledge production, knowledge dissemination, and knowledge-base of a community of commonality, such as an academic discipline or a professional community. The products of domain analysis range from controlled vocabularies and other knowledge organization systems, to scientific evidence about the growth and sharing of knowledge and the evolution of communities of discourse and practice.In the field of knowledge organization- both the science and the practice­ domain analysis is the basic research method for identifying the concepts that will be critical building blocks for knowledge organization systems. This book will survey the theoretical rationale for domain analysis, present tutorials in the specific methods of domain analysis, especially with regard to tools for visualizing knowledge domains. Focuses on the science and practice of organizing knowledge Includes step-by-step instructions to enable the book to be used as a textbook or a manual for researchers