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Author: Christophe Dessimoz
Publisher:
ISBN: 9781013267710
Category : Science
Languages : en
Pages : 298
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Book Description
This book provides a practical and self-contained overview of the Gene Ontology (GO), the leading project to organize biological knowledge on genes and their products across genomic resources. Written for biologists and bioinformaticians, it covers the state-of-the-art of how GO annotations are made, how they are evaluated, and what sort of analyses can and cannot be done with the GO. In the spirit of the Methods in Molecular Biology book series, there is an emphasis throughout the chapters on providing practical guidance and troubleshooting advice. Authoritative and accessible, The Gene Ontology Handbook serves non-experts as well as seasoned GO users as a thorough guide to this powerful knowledge system. This work was published by Saint Philip Street Press pursuant to a Creative Commons license permitting commercial use. All rights not granted by the work's license are retained by the author or authors.
Author: Christophe Dessimoz
Publisher:
ISBN: 9781013267710
Category : Science
Languages : en
Pages : 298
Get Book Here
Book Description
This book provides a practical and self-contained overview of the Gene Ontology (GO), the leading project to organize biological knowledge on genes and their products across genomic resources. Written for biologists and bioinformaticians, it covers the state-of-the-art of how GO annotations are made, how they are evaluated, and what sort of analyses can and cannot be done with the GO. In the spirit of the Methods in Molecular Biology book series, there is an emphasis throughout the chapters on providing practical guidance and troubleshooting advice. Authoritative and accessible, The Gene Ontology Handbook serves non-experts as well as seasoned GO users as a thorough guide to this powerful knowledge system. This work was published by Saint Philip Street Press pursuant to a Creative Commons license permitting commercial use. All rights not granted by the work's license are retained by the author or authors.
Author: Guido Küng
Publisher: Springer Science & Business Media
ISBN: 9401035148
Category : Philosophy
Languages : en
Pages : 219
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Book Description
It is the aim of the present study to introduce the reader to the ways of thinking of those contemporary philosophers who apply the tools of symbolic logic to classical philosophical problems. Unlike the "conti nental" reader for whom this work was originally written, the English speaking reader will be more familiar with most of the philosophers dis cussed in this book, and he will in general not be tempted to dismiss them indiscriminately as "positivists" and "nominalists". But the English version of this study may help to redress the balance in another respect. In view of the present emphasis on ordinary language and the wide spread tendency to leave the mathematical logicians alone with their technicalities, it seems not without merit to revive the interest in formal ontology and the construction of formal systems. A closer look at the historical account which will be given here, may convince the reader that there are several points in the historical develop ment whose consequences have not yet been fully assessed: I mention, e. g. , the shift from the traditional three-level semantics of sense and deno tation to the contemporary two-level semantics of representation; the relation of extensional structure and intensional content in the extensional systems of Wittgenstein and Carnap; the confusing changes in labelling the different kinds of analytic and apriori true sentences; etc. Among the philosophically interesting tools of symbolic logic Lesniewski's calculus of names deserves special attention.
Author: Zhanjiang (John) Liu
Publisher: John Wiley & Sons
ISBN: 1118782356
Category : Science
Languages : en
Pages : 605
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Book Description
Bioinformatics derives knowledge from computer analysis of biological data. In particular, genomic and transcriptomic datasets are processed, analysed and, whenever possible, associated with experimental results from various sources, to draw structural, organizational, and functional information relevant to biology. Research in bioinformatics includes method development for storage, retrieval, and analysis of the data. Bioinformatics in Aquaculture provides the most up to date reviews of next generation sequencing technologies, their applications in aquaculture, and principles and methodologies for the analysis of genomic and transcriptomic large datasets using bioinformatic methods, algorithm, and databases. The book is unique in providing guidance for the best software packages suitable for various analysis, providing detailed examples of using bioinformatic software and command lines in the context of real world experiments. This book is a vital tool for all those working in genomics, molecular biology, biochemistry and genetics related to aquaculture, and computational and biological sciences.
Author: Sébastien Harispe
Publisher: Springer
ISBN: 9783031010286
Category : Computers
Languages : en
Pages : 238
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Book Description
Artificial Intelligence federates numerous scientific fields in the aim of developing machines able to assist human operators performing complex treatments---most of which demand high cognitive skills (e.g. learning or decision processes). Central to this quest is to give machines the ability to estimate the likeness or similarity between things in the way human beings estimate the similarity between stimuli. In this context, this book focuses on semantic measures: approaches designed for comparing semantic entities such as units of language, e.g. words, sentences, or concepts and instances defined into knowledge bases. The aim of these measures is to assess the similarity or relatedness of such semantic entities by taking into account their semantics, i.e. their meaning---intuitively, the words tea and coffee, which both refer to stimulating beverage, will be estimated to be more semantically similar than the words toffee (confection) and coffee, despite that the last pair has a higher syntactic similarity. The two state-of-the-art approaches for estimating and quantifying semantic similarities/relatedness of semantic entities are presented in detail: the first one relies on corpora analysis and is based on Natural Language Processing techniques and semantic models while the second is based on more or less formal, computer-readable and workable forms of knowledge such as semantic networks, thesauri or ontologies. Semantic measures are widely used today to compare units of language, concepts, instances or even resources indexed by them (e.g., documents, genes). They are central elements of a large variety of Natural Language Processing applications and knowledge-based treatments, and have therefore naturally been subject to intensive and interdisciplinary research efforts during last decades. Beyond a simple inventory and categorization of existing measures, the aim of this monograph is to convey novices as well as researchers of these domains toward a better understanding of semantic similarity estimation and more generally semantic measures. To this end, we propose an in-depth characterization of existing proposals by discussing their features, the assumptions on which they are based and empirical results regarding their performance in particular applications. By answering these questions and by providing a detailed discussion on the foundations of semantic measures, our aim is to give the reader key knowledge required to: (i) select the more relevant methods according to a particular usage context, (ii) understand the challenges offered to this field of study, (iii) distinguish room of improvements for state-of-the-art approaches and (iv) stimulate creativity toward the development of new approaches. In this aim, several definitions, theoretical and practical details, as well as concrete applications are presented.
Author: B. Brodaric
Publisher: IOS Press
ISBN: 164368129X
Category : Computers
Languages : en
Pages : 282
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Book Description
FOIS is the flagship conference of the International Association for Ontology and its Applications, a non-profit organization which promotes interdisciplinary research and international collaboration at the intersection of philosophical ontology, linguistics, logic, cognitive science, and computer science, as well as in the applications of ontological analysis to conceptual modeling, knowledge engineering, knowledge management, information-systems development, library and information science, scientific research, and semantic technologies in general. This volume presents the 17 papers accepted for the 11th Formal Ontology in Information Systems conference (FOIS 2020). These papers cover a broad range of topics and are organized into 5 groups. Foundations is dedicated to the general ontological decisions providing a foundation for any ontology, both from a philosophical perspective and with an emphasis on applications. Social Entities is dedicated to the ontological analysis and formalization of various social entities, including secrets, legal theories, decisions, kinship, and cultural heritage. The papers in Intentionality and Embodiment analyze aspects of an agent's intentions, beliefs and desires, as well as the embodiment of functional relations. The section on Parts and Wholes is dedicated to mereology as well as the mereological analysis of certain types of entities (e.g., pluralities, information entities, and computer programs). Lastly, the papers in Methods are about ontology evaluation and use. Altogether, the papers reflect traditional FOIS themes with perhaps a greater emphasis on social and agent aspects, and will be of interest to all those whose work involves ontology and its applications.
Author: Robert E. Wood
Publisher: Northwestern University Press
ISBN: 9780810106505
Category : Philosophy
Languages : en
Pages : 162
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Book Description
Describes the origins, structure, and meaning of the leading philosophic work by the Jewish religious scholar.
Author: Amie Lynn Thomasson
Publisher: Oxford University Press, USA
ISBN: 0199385114
Category : Philosophy
Languages : en
Pages : 361
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Book Description
Existence questions have been topics for heated debates in metaphysics, but this book argues that they can often be answered easily, by trivial inferences from uncontroversial premises. This 'easy' approach to ontology leads to realism about disputed entities, and to the view that metaphysical disputes about existence questions are misguided.
Author: Vishal Jain
Publisher: John Wiley & Sons
ISBN: 1119641381
Category : Computers
Languages : en
Pages : 384
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Book Description
With the advancements of semantic web, ontology has become the crucial mechanism for representing concepts in various domains. For research and dispersal of customized healthcare services, a major challenge is to efficiently retrieve and analyze individual patient data from a large volume of heterogeneous data over a long time span. This requirement demands effective ontology-based information retrieval approaches for clinical information systems so that the pertinent information can be mined from large amount of distributed data. This unique and groundbreaking book highlights the key advances in ontology-based information retrieval techniques being applied in the healthcare domain and covers the following areas: Semantic data integration in e-health care systems Keyword-based medical information retrieval Ontology-based query retrieval support for e-health implementation Ontologies as a database management system technology for medical information retrieval Information integration using contextual knowledge and ontology merging Collaborative ontology-based information indexing and retrieval in health informatics An ontology-based text mining framework for vulnerability assessment in health and social care An ontology-based multi-agent system for matchmaking patient healthcare monitoring A multi-agent system for querying heterogeneous data sources with ontologies for reducing cost of customized healthcare systems A methodology for ontology based multi agent systems development Ontology based systems for clinical systems: validity, ethics and regulation
Author: Thomas Hofweber
Publisher: Oxford University Press
ISBN: 0198769830
Category : Mathematics
Languages : en
Pages : 382
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Book Description
Many significant problems in metaphysics are tied to ontological questions, but ontology and its relation to larger questions in metaphysics give rise to a series of puzzles that suggest that we don't fully understand what ontology is supposed to do, nor what ambitions metaphysics can have for finding out about what the world is like. Thomas Hofweber aims to solve these puzzles about ontology and consequently to make progress on four central metaphysical problems: the philosophy of arithmetic, the metaphysics of ordinary objects, the problem of universals, and the question whether reality is independent of us. Crucial parts of the proposed solution include considerations about quantification and its relationship to ontology, the place of reference in natural languages, the possibility of ineffable facts, the extent of empirical evidence in metaphysics, and whether metaphysics can properly be esoteric. Overall, Hofweber defends a rationalist account of arithmetic, an empiricist picture in the philosophy of ordinary objects, a restricted from of nominalism, and realism about reality, understood as all there is, but idealism about reality, understood as all that is the case. He defends metaphysics as having some questions of fact that are distinctly its own, with a limited form of autonomy from other parts of inquiry, but rejects several metaphysical projects and approaches as being based on a mistake.
Author: S. Borgo
Publisher: IOS Press
ISBN: 1614999104
Category : Computers
Languages : en
Pages : 278
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Book Description
FOIS is the flagship conference of the International Association for Ontology and its Applications (IAOA). Its interdisciplinary research focus lies at the intersection of philosophical ontology, linguistics, logic, cognitive science, and computer science, as well as in the applications of ontological analysis to conceptual modeling, knowledge engineering, knowledge management, information-systems development, library and information science, scientific research, and semantic technologies in general. This volume presents the proceedings of FOIS 2018, held in Cape Town, South Africa, from 19-21 September. It was the 10th edition and 20th anniversary of the conference series. The volume contains 19 papers grouped into 4 sections: Foundations (7 papers), Agents and Properties (4 papers), Methods and Tools (4 papers), and Applications (4 papers). Regarding the applications of ontologies, a broad spectrum of areas is covered, including in particular biology and medicine, IoT, engineering and linguistics. Formal Ontology in Information Systems - Proceedings of the 10th International Conference (FOIS 2018) will be of interest to researchers from all disciplines with an interest in formal ontology.
