Ocular Drug Delivery: Advances, Challenges and Applications

Ocular Drug Delivery: Advances, Challenges and Applications PDF Author: Richard T. Addo
Publisher: Springer
ISBN: 3319476912
Category : Medical
Languages : en
Pages : 190

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Book Description
The eye is a computerized system that has been designed for self-defense, and these defense mechanisms create challenges in administration of medications to the eye. Therefore, ocular drug delivery has been a major challenge to drug delivery researchers. There are on-going studies, in search of treatment especially for the diseases affecting the posterior segment of the eye. This book gives and overview of the background of ocular drug delivery and is unique for pharmacists, medical practitioners, students and drug delivery researchers.

Ocular Therapeutics

Ocular Therapeutics PDF Author: Thomas Yorio
Publisher: Academic Press
ISBN: 0080556779
Category : Science
Languages : en
Pages : 537

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Book Description
Ocular Therapeutics: Eye on New Discovery focuses on emerging areas in ocular research, from new approaches to dry eye to gene therapy in the management of retinal diseases. This comprehensive book features more than 25 chapters of information that will be vital for ocular investigators and ophthalmologists bringing them new information on promising therapeutics. It is the intent of this book to provide not only information on current approaches to treatment, but also in giving the reader a greater understanding as to what may become available for treating a number of important eye diseases. Each chapter features some new aspect of treatment that holds great promise for the future. The approach has been to concentrate on those areas of ocular diseases that are more prevalent. It also features new insight for drug delivery and for managing devasting diseases, such as macula edema and glaucoma, two of the leading causes of blindness in the United States. This book will serve as an important resource as it contains a number of relevant references highlighted for their importance to the field. New investigators will be able to obtain an historical perspective for each of the topics and to develop an understanding of the new research directions that are underway. Ocular Therapeutics: Eye on New Discovery is more than a reference book, as it also provides an important glimpse into the near future.* Contains information that is vital for ocular investigators and ophthalmologists bringing them new information on promising therapeutics.* Provides not only information on current approaches to treatment, but also gives the reader a greater understanding as to what may become available for treating a number of important eye diseases.* Historical perspective for each of the topics as well as an important glimpse into the near future to develop an understanding of the new research directions underway.* New insight for drug delivery and for managing devastating diseases, such as macula edema and glaucoma, two of the leading causes of blindness in the United States

Ophthalmic Drug Delivery Systems

Ophthalmic Drug Delivery Systems PDF Author: Ashim K. Mitra
Publisher: CRC Press
ISBN: 9780367446765
Category :
Languages : en
Pages : 847

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Book Description
The second edition of this text assembles significant ophthalmic advances and encompasses breakthroughs in gene therapy, ocular microdialysis, vitreous drug disposition modelling, and receptor/transporter targeted drug delivery.

Microneedles for Drug and Vaccine Delivery and Patient Monitoring

Microneedles for Drug and Vaccine Delivery and Patient Monitoring PDF Author: Ryan F. Donnelly
Publisher: John Wiley & Sons
ISBN: 1119305179
Category : Science
Languages : en
Pages : 458

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Book Description
Provides comprehensive coverage of microneedles for delivering and monitoring patient drugs and vaccines Microneedles are an incredibly active research area and have the potential to revolutionize the way many medicines and vaccines are delivered. This comprehensive research book covers the major aspects relating to the use of microneedle arrays in enhancing both transdermal and intradermal drug delivery and provides a sound background to the use of microneedle arrays in enhanced delivery applications. Beginning with a history of the field and the various methods employed to produce microneedles from different materials, Microneedles for Drug and Vaccine Delivery and Patient Monitoring discusses the penetration of the stratum corneum by microneedles and the importance of application method and force and microneedle geometry (height, shape, inter-needle spacing). Transdermal and intradermal delivery research using microneedles is comprehensively and critically reviewed, focusing on the outcomes of in vivo animal and human studies. The book describes the important topics of safety and patient acceptability studies carried out to date. It also covers in detail the growing area for microneedle use in the monitoring of interstitial fluid contents. Finally, it reviews translational and regulatory developments in the microneedles field and describes the work ongoing in industry. The only book currently available on microneedles Filled with tables, graphs, and black and white images (photographs, micrographs) Authored by four experts in pharmaceutics Microneedles for Drug and Vaccine Delivery and Patient Monitoring is an ideal source for researchers in industry and academia working on drug delivery and transdermal delivery in particular, as well as for advanced students in pharmacy and pharmaceutical sciences.

Advances and Challenges in Pharmaceutical Technology

Advances and Challenges in Pharmaceutical Technology PDF Author: Amit Kumar Nayak
Publisher: Academic Press
ISBN: 0128203005
Category : Medical
Languages : en
Pages : 572

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Book Description
Advances and Challenges in Pharmaceutical Technology: Materials, Process Development and Drug Delivery Strategies examines recent advancements in pharmaceutical technology. The book discusses common formulation strategies, including the use of tools for statistical formulation optimization, Quality by design (QbD), process analytical technology, and the uses of various pharmaceutical biomaterials, including natural polymers, synthetic polymers, modified natural polymers, bioceramics, and other bioinorganics. In addition, the book covers rapid advancements in the field by providing a thorough understanding of pharmaceutical processes, formulation developments, explorations, and exploitation of various pharmaceutical biomaterials to formulate pharmaceutical dosage forms. - Provides extensive information and analysis on recent advancements in the field of pharmaceutical technology - Includes contributions from global leaders and experts in academia, industry and regulatory agencies - Uses high quality illustrations, flow charts and tables to explain concepts and text to readers, along with practical examples and research case studies

Nanoformulations in Human Health

Nanoformulations in Human Health PDF Author: Sushama Talegaonkar
Publisher: Springer Nature
ISBN: 3030418588
Category : Medical
Languages : en
Pages : 548

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Book Description
This book is an amalgamation of knowledge, experience, and expertise in various aspects of nanotechnology, by experts who are proficient in designing of novel nanoformulations that are used in the treatment of various challenging and prevalent diseases. It is an exhaustive compilation of the multi-faceted arena of nanoformulations and the healthcare system that caters to the needs of academicians, scholars, researchers etc. The most important aspect of the book covers various types of nanoformulations and their applications in treatment of communicable and non-communicable diseases. Each chapter focuses on a particular nanoformulation as well as a disease including the pathophysiology of the disease, the current treatment modalities of diseases, the role of nanoformulation in treatment and other future aspects and directions for further work. Coverage includes neuropathic pain, colon targeting, nose-to-brain drug delivery, skin cancer, arthritis and tuberculosis.

Ocular Angiogenesis

Ocular Angiogenesis PDF Author: Joyce Tombran-Tink
Publisher: Springer Science & Business Media
ISBN: 1597450472
Category : Medical
Languages : en
Pages : 409

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Book Description
Leading academic and pharmaceutical researchers and clinicians from many disciplines synthesize and summarize current clinical and basic knowledge concerning abnormal growth of blood vessels in the eye, the cause of major neovascular eye diseases. The authors also identify and assess the most promising approaches with potential for commercial exploitation and discuss the challenges encountered in developing therapeutics for ocular neovascular diseases. Highlights include illuminating chapters on gene therapy and novel drug delivery systems and excellent summaries of the newest therapeutic approaches.

Treatise on Ocular Drug Delivery

Treatise on Ocular Drug Delivery PDF Author: Ashim K. Mitra
Publisher: Bentham Science Publishers
ISBN: 1608051757
Category : Medical
Languages : en
Pages : 301

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Book Description
A multidisciplinary approach is increasingly being adapted by the Pharmaceutical industry to tackle several challenges in developing efficacious treatment solutions. The field of Ophthalmology is no less different. Treatise on Ocular Drug Delivery is a unique collection of information put together by various experts in the field. One of the major goals behind this volume is to link clinical information with the current strategies employed in ocular drug delivery. This monograph covers a range of topics on ocular pharmacology. Chapters in the e-book cover several aspects of drug delivery research such as the biochemical background of specific eye diseases, challenges for ocular drug delivery, the role of influx and efflux transporters, novel drug delivery systems, pharmacokinetics, regulatory aspects, and patenting opportunities for researchers. This E-Book would serve as a suitable reference for pharmacy graduates, medical students, professional scientists and ophthalmic clinicians in academic and industrial laboratories.

Drug Delivery

Drug Delivery PDF Author: Binghe Wang
Publisher: John Wiley & Sons
ISBN: 1118833368
Category : Science
Languages : en
Pages : 740

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Book Description
Following its successful predecessor, this book covers the fundamentals, delivery routes and vehicles, and practical applications of drug delivery. In the 2nd edition, almost all chapters from the previous are retained and updated and several new chapters added to make a more complete resource and reference. • Helps readers understand progress in drug delivery research and applications • Updates and expands coverage to reflect advances in materials for delivery vehicles, drug delivery approaches, and therapeutics • Covers recent developments including transdermal and mucosal delivery, lymphatic system delivery, theranostics • Adds new chapters on nanoparticles, controlled drug release systems, theranostics, protein and peptide drugs, and biologics delivery

Emerging Trends in Nanomedicine

Emerging Trends in Nanomedicine PDF Author: Sanjay Singh
Publisher:
ISBN: 9789811599217
Category :
Languages : en
Pages : 0

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Book Description
This book illustrates the significance of nanotechnology in the delivery of anticancer and antimicrobial drugs, biomimetic technologies, tissue engineering, sensing, diagnostics, and artificial enzymes. It first briefly discusses the use of nanotechnology for the delivery of anticancer medications, and the concept and applications of catalytically active nanomaterial-based artificial enzymes for sensing and diagnostic applications. It then explores the use of silver nanoparticle-based novel antimicrobials, and comprehensively reviews the role of nanomaterials in developing biomedical implants and tissue engineering applications. Lastly, it offers a detailed description of nanotherapeutics for combating human protozoan parasitic infections. Cutting across the disciplines, this book serves as a guide for researchers and scientists in biotechnology, medical science and material science.