A Guide to Numerical Modelling in Systems Biology

A Guide to Numerical Modelling in Systems Biology PDF Author: Peter Deuflhard
Publisher: Springer
ISBN: 3319200593
Category : Mathematics
Languages : en
Pages : 185

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Book Description
This book is intended for students of computational systems biology with only a limited background in mathematics. Typical books on systems biology merely mention algorithmic approaches, but without offering a deeper understanding. On the other hand, mathematical books are typically unreadable for computational biologists. The authors of the present book have worked hard to fill this gap. The result is not a book on systems biology, but on computational methods in systems biology. This book originated from courses taught by the authors at Freie Universität Berlin. The guiding idea of the courses was to convey those mathematical insights that are indispensable for systems biology, teaching the necessary mathematical prerequisites by means of many illustrative examples and without any theorems. The three chapters cover the mathematical modelling of biochemical and physiological processes, numerical simulation of the dynamics of biological networks and identification of model parameters by means of comparisons with real data. Throughout the text, the strengths and weaknesses of numerical algorithms with respect to various systems biological issues are discussed. Web addresses for downloading the corresponding software are also included.

Introduction to Numerical Geodynamic Modelling

Introduction to Numerical Geodynamic Modelling PDF Author: Taras Gerya
Publisher: Cambridge University Press
ISBN: 0521887542
Category : Mathematics
Languages : en
Pages : 359

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Book Description
This user-friendly reference for students and researchers presents the basic mathematical theory, before introducing modelling of key geodynamic processes.

Numerical Models for Differential Problems

Numerical Models for Differential Problems PDF Author: Alfio Quarteroni
Publisher: Springer Science & Business
ISBN: 8847055229
Category : Mathematics
Languages : en
Pages : 668

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Book Description
In this text, we introduce the basic concepts for the numerical modelling of partial differential equations. We consider the classical elliptic, parabolic and hyperbolic linear equations, but also the diffusion, transport, and Navier-Stokes equations, as well as equations representing conservation laws, saddle-point problems and optimal control problems. Furthermore, we provide numerous physical examples which underline such equations. We then analyze numerical solution methods based on finite elements, finite differences, finite volumes, spectral methods and domain decomposition methods, and reduced basis methods. In particular, we discuss the algorithmic and computer implementation aspects and provide a number of easy-to-use programs. The text does not require any previous advanced mathematical knowledge of partial differential equations: the absolutely essential concepts are reported in a preliminary chapter. It is therefore suitable for students of bachelor and master courses in scientific disciplines, and recommendable to those researchers in the academic and extra-academic domain who want to approach this interesting branch of applied mathematics.

Numerical Modelling of Failure in Advanced Composite Materials

Numerical Modelling of Failure in Advanced Composite Materials PDF Author: Pedro P. Camanho
Publisher: Woodhead Publishing
ISBN: 0081003420
Category : Technology & Engineering
Languages : en
Pages : 562

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Book Description
Numerical Modelling of Failure in Advanced Composite Materials comprehensively examines the most recent analysis techniques for advanced composite materials. Advanced composite materials are becoming increasingly important for lightweight design in aerospace, wind energy, and mechanical and civil engineering. Essential for exploiting their potential is the ability to reliably predict their mechanical behaviour, particularly the onset and propagation of failure. Part One investigates numerical modeling approaches to interlaminar failure in advanced composite materials. Part Two considers numerical modelling approaches to intralaminar failure. Part Three presents new and emerging advanced numerical algorithms for modeling and simulation of failure. Part Four closes by examining the various engineering and scientific applications of numerical modeling for analysis of failure in advanced composite materials, such as prediction of impact damage, failure in textile composites, and fracture behavior in through-thickness reinforced laminates. - Examines the most recent analysis models for advanced composite materials in a coherent and comprehensive manner - Investigates numerical modelling approaches to interlaminar failure and intralaminar failure in advanced composite materials - Reviews advanced numerical algorithms for modeling and simulation of failure - Examines various engineering and scientific applications of numerical modelling for analysis of failure in advanced composite materials

Numerical Modelling and Simulation of Metal Processing

Numerical Modelling and Simulation of Metal Processing PDF Author: Christof Sommitsch
Publisher: MDPI
ISBN: 303651080X
Category : Technology & Engineering
Languages : en
Pages : 374

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Book Description
This book deals with metal processing and its numerical modelling and simulation. In total, 21 papers from different distinguished authors have been compiled in this area. Various processes are addressed, including solidification, TIG welding, additive manufacturing, hot and cold rolling, deep drawing, pipe deformation, and galvanizing. Material models are developed at different length scales from atomistic simulation to finite element analysis in order to describe the evolution and behavior of materials during thermal and thermomechanical treatment. Materials under consideration are carbon, Q&T, DP, and stainless steels; ductile iron; and aluminum, nickel-based, and titanium alloys. The developed models and simulations shall help to predict structure evolution, damage, and service behavior of advanced materials.

Numerical Modelling of Bulk Superconductor Magnetisation

Numerical Modelling of Bulk Superconductor Magnetisation PDF Author: Mark Ainslie
Publisher:
ISBN: 9780750313346
Category : SCIENCE
Languages : en
Pages : 0

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Book Description
This book provides readers with numerical analysis techniques to model the magnetisation of bulk superconductors based on the finite element method. Applications of magnetised bulk superconductors are wide ranging in engineering due to their greatly enhanced magnetic field compared to conventional magnets. Their uses include rotating electric machines, magnetic resonance imaging (MRI), nuclear magnetic resonance (NMR) systems and magnetic separation. Numerical modelling is a particularly important and cost-effective method to guide both superconducting material processing and practical device design. It has been used successfully to interpret experimental results and the physical behaviour and properties of bulk superconductors during their various magnetisation processes, to predict and propose new magnetisation techniques and to design and predict the performance of bulk superconductor-based devices. The book provides the necessary fundamentals of bulk superconducting materials, how to model these and their various magnetisation processes and an in-depth summary of the current state-of-the-art in the field. Throughout the book, example models, implemented in the software package COMSOL Multiphysicsa, are provided so that readers may carry out modelling of their own. The current state-of-the-art in modelling bulk superconductors is summarised, including case studies that highlight the usefulness of such models.

Numerical Modelling of Wave Energy Converters

Numerical Modelling of Wave Energy Converters PDF Author: Matt Folley
Publisher: Academic Press
ISBN: 0128032111
Category : Technology & Engineering
Languages : en
Pages : 308

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Book Description
Numerical Modelling of Wave Energy Converters: State-of-the Art Techniques for Single WEC and Converter Arrays presents all the information and techniques required for the numerical modelling of a wave energy converter together with a comparative review of the different available techniques. The authors provide clear details on the subject and guidance on its use for WEC design, covering topics such as boundary element methods, frequency domain models, spectral domain models, time domain models, non linear potential flow models, CFD models, semi analytical models, phase resolving wave propagation models, phase averaging wave propagation models, parametric design and control optimization, mean annual energy yield, hydrodynamic loads assessment, and environmental impact assessment. Each chapter starts by defining the fundamental principles underlying the numerical modelling technique and finishes with a discussion of the technique's limitations and a summary of the main points in the chapter. The contents of the chapters are not limited to a description of the mathematics, but also include details and discussion of the current available tools, examples available in the literature, and verification, validation, and computational requirements. In this way, the key points of each modelling technique can be identified without having to get deeply involved in the mathematical representation that is at the core of each chapter. The book is separated into four parts. The first two parts deal with modelling single wave energy converters; the third part considers the modelling of arrays; and the final part looks at the application of the different modelling techniques to the four most common uses of numerical models. It is ideal for graduate engineers and scientists interested in numerical modelling of wave energy converters, and decision-makers who must review different modelling techniques and assess their suitability and output. - Consolidates in one volume information and techniques for the numerical modelling of wave energy converters and converter arrays, which has, up until now, been spread around multiple academic journals and conference proceedings making it difficult to access - Presents a comparative review of the different numerical modelling techniques applied to wave energy converters, discussing their limitations, current available tools, examples, and verification, validation, and computational requirements - Includes practical examples and simulations available for download at the book's companion website - Identifies key points of each modelling technique without getting deeply involved in the mathematical representation

Numerical Modelling

Numerical Modelling PDF Author: Peep Miidla
Publisher: BoD – Books on Demand
ISBN: 9535102192
Category : Computers
Languages : en
Pages : 422

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Book Description
This book demonstrates applications and case studies performed by experts for professionals and students in the field of technology, engineering, materials, decision making management and other industries in which mathematical modelling plays a role. Each chapter discusses an example and these are ranging from well-known standards to novelty applications. Models are developed and analysed in details, authors carefully consider the procedure for constructing a mathematical replacement of phenomenon under consideration. For most of the cases this leads to the partial differential equations, for the solution of which numerical methods are necessary to use. The term Model is mainly understood as an ensemble of equations which describe the variables and interrelations of a physical system or process. Developments in computer technology and related software have provided numerous tools of increasing power for specialists in mathematical modelling. One finds a variety of these used to obtain the numerical results of the book.

Advanced Numerical Modelling of Wave Structure Interaction

Advanced Numerical Modelling of Wave Structure Interaction PDF Author: David M Kelly
Publisher: CRC Press
ISBN: 1351119532
Category : Mathematics
Languages : en
Pages : 270

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Book Description
This book will serve as a reference guide, and state-of-the-art review, for the wide spectrum of numerical models and computational techniques available to solve some of the most challenging problems in coastal engineering. The topics covered in this book, are explained fundamentally from a numerical perspective and also include practical examples applications. Important classic themes such as wave generation, propagation and breaking, turbulence modelling and sediment transport are complemented by hot topics such as fluid and structure interaction or multi-body interaction to provide an integral overview on numerical techniques for coastal engineering. Through the vision of 10 high impact authors, each an expert in one or more of the fields included in this work, the chapters offer a broad perspective providing several different approaches, which the readers can compare critically to select the most suitable for their needs. Advanced Numerical Modelling of Wave Structure Interaction will be useful for a wide audience, including PhD students, research scientists, numerical model developers and coastal engineering consultants alike.

Innovative Numerical Modelling in Geomechanics

Innovative Numerical Modelling in Geomechanics PDF Author: Luis Ribeiro e Sousa
Publisher: CRC Press
ISBN: 0203829808
Category : Technology & Engineering
Languages : en
Pages : 475

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Book Description
Since the 1990s five books onApplications of Computational Mechanics in Geotechnical Engineering have been published. Innovative Numerical Modelling in Geomechanics is the 6th and final book in this series, and contains papers written by leading experts on computational mechanics. The book treats highly relevant topics in the field of geotechnic