Novel Optical Endoscopes for Early Cancer Diagnosis and Therapy

Novel Optical Endoscopes for Early Cancer Diagnosis and Therapy PDF Author: Dale Jonathan Waterhouse
Publisher: Springer
ISBN: 3030214818
Category : Science
Languages : en
Pages : 161

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Book Description
This thesis describes the design, development, characterisation and clinical translation of three novel devices for optical endoscopic imaging. Over the past decade, rapid innovation in optics and photonics has led to the availability of low-cost and high-performance optical technologies that can be exploited for biomedical applications, but relatively few have been translated into clinic. The work presented outlines for the first time, a comprehensive analysis of the common barriers and unique challenges associated with the translation of optical imaging techniques. To assist developers streamline translation of optical imaging devices in future, a roadmap to clinical translation is outlined, and key translational characteristics are defined. Guided by these, subsequent development of endoscopic devices resulted in preparation and approval of endoscopes for first in human trials in the oesophagus, for early detection of cancer, and in the brain, for delineation of tumour during surgical resection. The thesis culminates in the presentation of results from the first in human use of a compact multispectral endoscope for imaging endogenous tissue contrast in the oesophagus. With continuation of the work as outlined at the end of this thesis, the novel techniques described have the potential to improve the standard of care in their respective indications.

Novel Optical Endoscopes for Early Cancer Diagnosis and Therapy

Novel Optical Endoscopes for Early Cancer Diagnosis and Therapy PDF Author: Dale Jonathan Waterhouse
Publisher: Springer
ISBN: 3030214818
Category : Science
Languages : en
Pages : 161

Get Book Here

Book Description
This thesis describes the design, development, characterisation and clinical translation of three novel devices for optical endoscopic imaging. Over the past decade, rapid innovation in optics and photonics has led to the availability of low-cost and high-performance optical technologies that can be exploited for biomedical applications, but relatively few have been translated into clinic. The work presented outlines for the first time, a comprehensive analysis of the common barriers and unique challenges associated with the translation of optical imaging techniques. To assist developers streamline translation of optical imaging devices in future, a roadmap to clinical translation is outlined, and key translational characteristics are defined. Guided by these, subsequent development of endoscopic devices resulted in preparation and approval of endoscopes for first in human trials in the oesophagus, for early detection of cancer, and in the brain, for delineation of tumour during surgical resection. The thesis culminates in the presentation of results from the first in human use of a compact multispectral endoscope for imaging endogenous tissue contrast in the oesophagus. With continuation of the work as outlined at the end of this thesis, the novel techniques described have the potential to improve the standard of care in their respective indications.

Endoscopy

Endoscopy PDF Author: Costin Teodor Streba
Publisher: BoD – Books on Demand
ISBN: 1789851254
Category : Medical
Languages : en
Pages : 152

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Book Description
Endoscopic techniques are widely used for screening, diagnostic and therapeutic maneuvers in all groups of patients and for a large spectrum of complaints. The availability of basic iterations of endoscopic techniques made screening programs for various diseases viable in most parts of the world, while the advent of modern techniques opens new perspectives for rapid and correct diagnosis. Going beyond normal human vision, innovative techniques opened the prospect of in-situ pathology. Endoscopic ultrasound has made incredible progress in recent years. Reaching the smaller orifices by endoscopy was a major step forward in the surveillance of previously inaccessible lesions. Investigatory techniques were complemented by advances in therapy, with novel applications in many major areas of medicine.

Flexible Bronchoscopy

Flexible Bronchoscopy PDF Author: Ko-Pen Wang
Publisher: John Wiley & Sons
ISBN: 1119389054
Category : Medical
Languages : en
Pages : 496

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Book Description
In this fourth edition of the popular Flexible Bronchoscopy, which has been revised and updated throughout, the world's leading specialists discuss the technical and procedural aspects of performing diagnostic and therapeutic bronchoscopy. Four new chapters have been added, taking into account new developments in EBUS and electromagnetic navigation.

Sources of Medical Technology

Sources of Medical Technology PDF Author: Institute of Medicine
Publisher: National Academies Press
ISBN: 0309176689
Category : Medical
Languages : en
Pages : 254

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Book Description
Evidence suggests that medical innovation is becoming increasingly dependent on interdisciplinary research and on the crossing of institutional boundaries. This volume focuses on the conditions governing the supply of new medical technologies and suggest that the boundaries between disciplines, institutions, and the private and public sectors have been redrawn and reshaped. Individual essays explore the nature, organization, and management of interdisciplinary R&D in medicine; the introduction into clinical practice of the laser, endoscopic innovations, cochlear implantation, cardiovascular imaging technologies, and synthetic insulin; the division of innovating labor in biotechnology; the government- industry-university interface; perspectives on industrial R&D management; and the growing intertwining of the public and proprietary in medical technology.

Gastroenterology and Nutrition E-Book

Gastroenterology and Nutrition E-Book PDF Author: Derek G. Waller
Publisher: Elsevier Health Sciences
ISBN: 0702071250
Category : Medical
Languages : en
Pages : 593

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Book Description
Gastroenterology & Nutrition is a new e-book in a collection of subject-themed e-books containing relevant key articles from Medicine. The e-books provide a perfect source of revision for post-graduate exams in clinical medicine and portfolio material for life-long learning. As well as mapping to the UK Core Medical Training curriculum, these e-books also enable anyone with a short-term interest in a specific area to buy individual articles at a price-point that will give affordable access to all readers (from medical students to GPs and practitioners in related areas). The quality of user experience on mobiles, tablets and laptops will be an added bonus for learning on the move. The whole board has been involved in the creation of this content and are therefore listed as authors on all the e-books. In addition we extend our warm thanks for their contribution to these e-books to the past Chairman Allister Vale (who stepped down from the board in 2015) and to John Mucklow, who stepped down in 2016. Derek Waller, on behalf of the Editorial Board About the journal The parent journal (www.medicinejournal.co.uk) is a rolling, continuously updated review of clinical medicine over a 4-year cycle covering all the important topics for core medical training. Its Editorial Board comprises some of Europe’s most influential specialists. The journal’s articles are refreshed, updated, augmented or replaced as appropriate each time the subject is due for revision to provide a concise overview of knowledge and practice core to the curriculum. Each article is written by invited experts and overseen by the relevant subject specialist on the Board. A trainee representative on the Board ensures relevance and accessibility for exam candidates. About the Medicine journal e-books Gastroenterology & Nutrition is a new e-book in a collection of subject-themed e-books containing relevant key articles from Medicine. The e-books provide a perfect source of revision for post-graduate exams in clinical medicine and portfolio material for life-long learning. As well as mapping to the UK Core Medical Training curriculum, these e-books also enable anyone with a short-term interest in a specific area to buy individual articles at a price-point that will give affordable access to all readers (from medical students to GPs and practitioners in related areas). The quality of user experience on mobiles, tablets and laptops will be an added bonus for learning on the move. The whole board has been involved in the creation of this content and are therefore listed as authors on all the e-books. In addition we extend our warm thanks for their contribution to these e-books to the past Chairman Allister Vale (who stepped down from the board in 2015) and to John Mucklow, who stepped down in 2016. Derek Waller, on behalf of the Editorial Board About the journal The parent journal (www.medicinejournal.co.uk) is a rolling, continuously updated review of clinical medicine over a 4-year cycle covering all the important topics for core medical training. Its Editorial Board comprises some of Europe’s most influential specialists. The journal’s articles are refreshed, updated, augmented or replaced as appropriate each time the subject is due for revision to provide a concise overview of knowledge and practice core to the curriculum. Each article is written by invited experts and overseen by the relevant subject specialist on the Board. A trainee representative on the Board ensures relevance and accessibility for exam candidates.

Biomedical Optical Imaging

Biomedical Optical Imaging PDF Author: James G. Fujimoto
Publisher: Oxford University Press
ISBN: 0199722293
Category : Science
Languages : en
Pages : 435

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Book Description
Biomedical optical imaging is a rapidly emerging research area with widespread fundamental research and clinical applications. This book gives an overview of biomedical optical imaging with contributions from leading international research groups who have pioneered many of these techniques and applications. A unique research field spanning the microscopic to the macroscopic, biomedical optical imaging allows both structural and functional imaging. Techniques such as confocal and multiphoton microscopy provide cellular level resolution imaging in biological systems. The integration of this technology with exogenous chromophores can selectively enhance contrast for molecular targets as well as supply functional information on processes such as nerve transduction. Novel techniques integrate microscopy with state-of-the-art optics technology, and these include spectral imaging, two photon fluorescence correlation, nonlinear nanoscopy; optical coherence tomography techniques allow functional, dynamic, nanoscale, and cross-sectional visualization. Moving to the macroscopic scale, spectroscopic assessment and imaging methods such as fluorescence and light scattering can provide diagnostics of tissue pathology including neoplastic changes. Techniques using light diffusion and photon migration are a means to explore processes which occur deep inside biological tissues and organs. The integration of these techniques with exogenous probes enables molecular specific sensitivity.

Methods of Cancer Diagnosis, Therapy and Prognosis

Methods of Cancer Diagnosis, Therapy and Prognosis PDF Author: M. A. Hayat
Publisher: Springer Science & Business Media
ISBN: 1402095457
Category : Medical
Languages : en
Pages : 511

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Book Description
This fourth volume in a series devoted to cancer treatment discusses various methodologies for the diagnosis, therapy and prognosis of colorectal cancer. It covers the latest information including standard and emerging therapies and technological advances.

Abeloff's Clinical Oncology E-Book

Abeloff's Clinical Oncology E-Book PDF Author: John E. Niederhuber
Publisher: Elsevier Health Sciences
ISBN: 1455728810
Category : Medical
Languages : en
Pages : 2712

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Book Description
Practical and clinically focused, Abeloff’s Clinical Oncology is a trusted medical reference book designed to capture the latest scientific discoveries and their implications for cancer diagnosis and management of cancer in the most accessible manner possible. Abeloff’s equips everyone involved - from radiologists and oncologists to surgeons and nurses - to collaborate effectively and provide the best possible cancer care. Consult this title on your favorite e-reader, conduct rapid searches, and adjust font sizes for optimal readability. Select the most appropriate tests and imaging studies for cancer diagnosis and staging of each type of cancer, and manage your patients in the most effective way possible by using all of the latest techniques and approaches in oncology. Enhance your understanding of complex concepts with a color art program that highlights key points and illustrates relevant scientific and clinical problems. Stay at the forefront of the latest developments in cancer pharmacology, oncology and healthcare policy, survivorship in cancer, and many other timely topics. See how the most recent cancer research applies to practice through an increased emphasis on the relevance of new scientific discoveries and modalities within disease chapters. Streamline clinical decision making with abundant new treatment and diagnostic algorithms as well as concrete management recommendations. Take advantage of the collective wisdom of preeminent multidisciplinary experts in the field of oncology, including previous Abeloff’s editors John E. Niederhuber, James O. Armitage, and Michael B. Kastan as well as new editors James H. Doroshow from the National Cancer Institute and Joel E. Tepper of Gunderson & Tepper: Clinical Radiation Oncology. Quickly and effortlessly access the key information you need with the help of an even more user-friendly, streamlined format. Access the complete contents anytime, anywhere at Expert Consult, and test your mastery of the latest knowledge with 500 online multiple-choice review questions.

Safety in Minimal Access Surgery

Safety in Minimal Access Surgery PDF Author: Om Tantia
Publisher: Jaypee Brothers Medical Publishers
ISBN: 9390595576
Category : Medical
Languages : en
Pages : 337

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Book Description
Chapter 1. Safety in Operation Theatre Chapter 2. Sterilisation for Safe Minimal Access Surgery: Evidence and Recommendations Chapter 3. Safety in Energy Sources in Laparoscopic Surgery Chapter 4. Ergonomics: What is Safe for Surgeon? Evidence and Recommendations Chapter 5. Safety in Anaesthesia for Minimal Access Surgery Chapter 6. Safety in MAS during COVID-19 Era Chapter 7. Safe Access in Minimal Access Surgery: Evidence and Recommendations Chapter 8. Safe Laparoscopic Cholecystectomy: Evidence and Recommendations Chapter 9. Safe Laparoscopic CBD Exploration: Evidence and Recommendations Chapter 10. Safe Surgery for Pseudo-Pancreas Cyst: Evidence and Recommendations Chapter 11. Safety Issues in Management of Liver Hydatid Disease Chapter 12. Safe Laparoscopic Splenectomy: Evidence and Recommendations Chapter 13. Safe Adrenalectomy: Evidence and Recommendations Chapter 14. Safety in Surgery for Hiatus Hernia: Evidence and Recommendations Chapter 15. Safety in Surgery for Achalasia Cardia: Evidence and Recommendations Chapter 16. Safety in Colorectal Surgery Chapter 17. Safe Laparoscopic Appendectomy: Evidence and Recommendations Chapter 18. Safe Rectopexy: Evidence and Recommendations Chapter 19. Safe Laparoscopic Trans-abdominal Pre-peritoneal (TAPP) Repair of Groin Hernia: Evidence and Recommendations Chapter 20. Safe Laparoscopic Total Extra-peritoneal (TEP) Repair of Groin Hernia: Evidence and Recommendations Chapter 21. Safe IPOM/IPOM Plus Repair: Evidence and Recommendations Chapter 22. Safety in Abdominal Wall Reconstruction: Evidence and Recommendations Chapter 23. Safety in Sleeve Gastrectomy: Evidence and Recommendations Chapter 24. Safe Roux-en-Y Gastric Bypass: Evidence and Recommendations Chapter 25. Safe Mini Gastric Bypass: Evidence and Recommendations Chapter 26. Safe Laparoscopic Hysterectomy: Evidence and Recommendations Chapter 27. Safety in Robotic Surgery: Evidence and Recommendations

Medical Imaging in Clinical Practice

Medical Imaging in Clinical Practice PDF Author: Okechukwu Felix Erondu
Publisher: BoD – Books on Demand
ISBN: 9535109863
Category : Medical
Languages : en
Pages : 366

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Book Description
Medical Imaging in Clinical Practice is a compendium of the various applications of imaging modalities in specific clinical conditions. It captures in an easy to read manner, the experiences of various experts drawn from across the globe. It explores the conventional techniques, advanced modalities and on going research efforts in the ever widening horizon of medical imaging. The various topics would be relevant to residents, radiologists and specialists who order and interpret various medical imaging procedures. It is an essential for the inquisitive mind, seeking to understand the scope of medical imaging in clinical practice.