Author: Aisling M. Lakes
Publisher:
ISBN:
Category : Asymmetric synthesis
Languages : en
Pages : 182
Book Description
Novel Diamine and Phosphinamine Ligands and Their Application in Asymmetric Catalysis
Author: Aisling M. Lakes
Publisher:
ISBN:
Category : Asymmetric synthesis
Languages : en
Pages : 182
Book Description
Publisher:
ISBN:
Category : Asymmetric synthesis
Languages : en
Pages : 182
Book Description
Asymmetric Catalysis Using Phosphinamine and Diamine Ligands Containing a Trans-2,5-Dialkylpyrrolidinyl Unit
Author: Annette Farrell
Publisher:
ISBN:
Category : Asymmetric synthesis
Languages : en
Pages : 167
Book Description
Publisher:
ISBN:
Category : Asymmetric synthesis
Languages : en
Pages : 167
Book Description
Novel Axially Chiral Phosphinamine Ligands for Asymmetric Catalysis
Author: Anne-Marie Carroll
Publisher:
ISBN:
Category : Chirality
Languages : en
Pages : 278
Book Description
Publisher:
ISBN:
Category : Chirality
Languages : en
Pages : 278
Book Description
Synthesis and Use in Asymmetric Catalysis of Novel Diphosphine Ligands
Author: Piotr Wiktor Osiński
Publisher:
ISBN:
Category :
Languages : en
Pages : 176
Book Description
Publisher:
ISBN:
Category :
Languages : en
Pages : 176
Book Description
Synthesis of Optically Pure Nitrogenated Ligands and Their Uses in Asymmetric Catalysis
Author: Bilal El Asaad
Publisher:
ISBN:
Category :
Languages : en
Pages : 0
Book Description
New chiral N-arylated diamine ligands, derived from 1,2-diaminocyclohexane and a and ß-cyclic-aromatic ketone, were synthesized by dehydrogenative alkylation catalyzed by palladium on carbon (Pd/C). This method, allowed to prepare a series of chiral N,N-diarylated diamine and N-aryl diamine ligands with very good isolated yield.First of all, the applicability of the synthesized chiral diamine ligands was successfully examined in asymmetric transfer hydrogenation with homogeneous iridium catalyst associated to formic acid and its sodium salt. Various aromatic ketones were reduced to chiral alchohol with a complete conversion and high enantioselectivity (ee up to 93%). Then, two of the prepared chiral diamine, N,N'-dinaphtyl diaminocylohexane and N-naphtyl diaminocylohexane combined to copper (II), have been evaluated in asymmetric Henry reaction between benzaldehyde derivatives and nitromethane leading to ß-nitro-aryl-alcohol with good enantioselectivities (ee up to 83%) and good isolated yields.Furthermore, we transform these two ligands into imidazolinium salts precursor of carbenes, for further application in asymmetric catalysis. The mono N-arylated diamine was transformed into mono-thiourea ligand. These three new ligands were obtained with very good isolated yields.
Publisher:
ISBN:
Category :
Languages : en
Pages : 0
Book Description
New chiral N-arylated diamine ligands, derived from 1,2-diaminocyclohexane and a and ß-cyclic-aromatic ketone, were synthesized by dehydrogenative alkylation catalyzed by palladium on carbon (Pd/C). This method, allowed to prepare a series of chiral N,N-diarylated diamine and N-aryl diamine ligands with very good isolated yield.First of all, the applicability of the synthesized chiral diamine ligands was successfully examined in asymmetric transfer hydrogenation with homogeneous iridium catalyst associated to formic acid and its sodium salt. Various aromatic ketones were reduced to chiral alchohol with a complete conversion and high enantioselectivity (ee up to 93%). Then, two of the prepared chiral diamine, N,N'-dinaphtyl diaminocylohexane and N-naphtyl diaminocylohexane combined to copper (II), have been evaluated in asymmetric Henry reaction between benzaldehyde derivatives and nitromethane leading to ß-nitro-aryl-alcohol with good enantioselectivities (ee up to 83%) and good isolated yields.Furthermore, we transform these two ligands into imidazolinium salts precursor of carbenes, for further application in asymmetric catalysis. The mono N-arylated diamine was transformed into mono-thiourea ligand. These three new ligands were obtained with very good isolated yields.
The Synthesis of Chiral P, N Ligands and Their Applications in Asymmetric Catalysis
Author: Cian Reid
Publisher:
ISBN:
Category :
Languages : en
Pages : 0
Book Description
Publisher:
ISBN:
Category :
Languages : en
Pages : 0
Book Description
Synthesis of New Chiral Phosphine Ligands and Their Applications in Asymmetric Catalysis
Author: Murthy Narasimha Cheemala
Publisher:
ISBN:
Category :
Languages : en
Pages : 191
Book Description
Publisher:
ISBN:
Category :
Languages : en
Pages : 191
Book Description
Axially Chiral Phosphinamine Ligands in Asymmetric Catalysis
Author: Cormac Paul Saunders
Publisher:
ISBN:
Category : Asymmetric synthesis
Languages : en
Pages : 243
Book Description
Publisher:
ISBN:
Category : Asymmetric synthesis
Languages : en
Pages : 243
Book Description
The Preparation, Resolution and Application of Axially Chiral Phosphinamine Ligands in Asymmetric Catalysis
Author: David John Connolly
Publisher:
ISBN:
Category : Asymmetric synthesis
Languages : en
Pages : 318
Book Description
Publisher:
ISBN:
Category : Asymmetric synthesis
Languages : en
Pages : 318
Book Description
Novel Chiral Di-N-heterocyclic Carbene and Hybrid Phosphine-N-heterocyclic Carbene Ligands and Their Application to Transition Metal Mediated Asymmetric Catalysis
Author:
Publisher:
ISBN:
Category :
Languages : en
Pages : 334
Book Description
Publisher:
ISBN:
Category :
Languages : en
Pages : 334
Book Description