Author: Phindile Jonathan Klaas
Publisher:
ISBN:
Category : Quinoline
Languages : en
Pages : 202
Book Description
Novel Approaches to the Synthesis of Quinoline Derivatives
Author: Phindile Jonathan Klaas
Publisher:
ISBN:
Category : Quinoline
Languages : en
Pages : 202
Book Description
Publisher:
ISBN:
Category : Quinoline
Languages : en
Pages : 202
Book Description
Convenient Synthesis, Antimicrobial Evaluation and Molecular Modeling of Some Novel Quinoline Derivatives
Author:
Publisher:
ISBN:
Category :
Languages : en
Pages :
Book Description
Publisher:
ISBN:
Category :
Languages : en
Pages :
Book Description
Rearrangements in the Indolo[2,3-b]quinoline System
Author: Nicholas Voƻte
Publisher:
ISBN:
Category : Claisen rearrangement
Languages : en
Pages : 0
Book Description
Publisher:
ISBN:
Category : Claisen rearrangement
Languages : en
Pages : 0
Book Description
Heterocycles
Author: B. P. Nandeshwarappa
Publisher:
ISBN: 9781839690037
Category :
Languages : en
Pages : 202
Book Description
Publisher:
ISBN: 9781839690037
Category :
Languages : en
Pages : 202
Book Description
Synthesis of Novel Quinoline Derivatives and Their Cytotoxicity in A549 Lung Cancer Cells
Author: S'busiso Mfan'vele Nkosi
Publisher:
ISBN:
Category : Cell-mediated cytotoxicity
Languages : en
Pages : 308
Book Description
Publisher:
ISBN:
Category : Cell-mediated cytotoxicity
Languages : en
Pages : 308
Book Description
Quinoline Heterocycles
Author: Rajesh Y B R D
Publisher:
ISBN:
Category : Electronic books
Languages : en
Pages : 0
Book Description
Among heterocyclic compounds, quinoline is a privileged scaffold that appears as an important construction motif for the development of new drugs. Quinoline nucleus is endowed with a variety of therapeutic activities, and new quinolone derivatives are known to be biologically active compounds possessing several pharmacological activities. Many new therapeutic agents have been developed by using quinoline nucleus. Hence, quinoline and its derivatives form an important class of heterocyclic compounds for the new drug development. Numerous synthetic routes have been developed for the synthesis of quinoline and its derivatives due to its wide range of biological and pharmacological activities. The article covers the synthesis as well as biological activities of quinoline derivatives such as antimalarial, anticancer, antibacterial, anthelmintic, antiviral, antifungal, anti-inflammatory, analgesic, cardiovascular, central nervous system, hypoglycemic, and miscellaneous activities.
Publisher:
ISBN:
Category : Electronic books
Languages : en
Pages : 0
Book Description
Among heterocyclic compounds, quinoline is a privileged scaffold that appears as an important construction motif for the development of new drugs. Quinoline nucleus is endowed with a variety of therapeutic activities, and new quinolone derivatives are known to be biologically active compounds possessing several pharmacological activities. Many new therapeutic agents have been developed by using quinoline nucleus. Hence, quinoline and its derivatives form an important class of heterocyclic compounds for the new drug development. Numerous synthetic routes have been developed for the synthesis of quinoline and its derivatives due to its wide range of biological and pharmacological activities. The article covers the synthesis as well as biological activities of quinoline derivatives such as antimalarial, anticancer, antibacterial, anthelmintic, antiviral, antifungal, anti-inflammatory, analgesic, cardiovascular, central nervous system, hypoglycemic, and miscellaneous activities.
New Quinoline Derivatives: Synthesis and Evaluation for Antiinflammatory and Analgesic Properties. Note 2
Author: Luisa Savini
Publisher:
ISBN:
Category :
Languages : en
Pages : 21
Book Description
Publisher:
ISBN:
Category :
Languages : en
Pages : 21
Book Description
Synthesis of Bioactive Heterocycles Using 3-Acetyl Quinolines
Author: V. Vijayakumar
Publisher: LAP Lambert Academic Publishing
ISBN: 9783659202148
Category :
Languages : en
Pages : 248
Book Description
Quinoline heterocycles found to have diverse biological activities and 3-functionalised quinolines are important intermediates for the synthesis of various quinoline derivatives. 3-acetyl-4-hydroxy-quinolin-2(1H)-one and 6-chloro-3-acetyl-4-phenyl-2-methyl quinoline were chosen as intermediates for the synthesis of some novel quinoline derivatives. In particular, only a few methods are available for the synthesis of 3-acetyl-4-hydroxy-quinolin-2(1H)-one, which involve either two step or multistep reaction protocols. In the present work, a rapid, efficient and one pot procedure for the synthesis of 3-acetyl-4-hydroxy-quinolin-2(1H)-ones has been developed both by conventional and microwave assisted synthesis. The 3-acetyl quinolines were converted into chalcones which in turn converted to quinoline-3-yl pyrazolines and quinoline-3-yl isoxazolines and a few into 3-(2, 4-substitutedstyryl)isoxazolo[4,5-c]quinolin-4(5H)-ones. These compounds were explored for their anti-microbial and cyctotoxicity studies.
Publisher: LAP Lambert Academic Publishing
ISBN: 9783659202148
Category :
Languages : en
Pages : 248
Book Description
Quinoline heterocycles found to have diverse biological activities and 3-functionalised quinolines are important intermediates for the synthesis of various quinoline derivatives. 3-acetyl-4-hydroxy-quinolin-2(1H)-one and 6-chloro-3-acetyl-4-phenyl-2-methyl quinoline were chosen as intermediates for the synthesis of some novel quinoline derivatives. In particular, only a few methods are available for the synthesis of 3-acetyl-4-hydroxy-quinolin-2(1H)-one, which involve either two step or multistep reaction protocols. In the present work, a rapid, efficient and one pot procedure for the synthesis of 3-acetyl-4-hydroxy-quinolin-2(1H)-ones has been developed both by conventional and microwave assisted synthesis. The 3-acetyl quinolines were converted into chalcones which in turn converted to quinoline-3-yl pyrazolines and quinoline-3-yl isoxazolines and a few into 3-(2, 4-substitutedstyryl)isoxazolo[4,5-c]quinolin-4(5H)-ones. These compounds were explored for their anti-microbial and cyctotoxicity studies.
Novel Approaches to the Synthesis of Cubitene
Author: Michael J. Davis
Publisher:
ISBN:
Category : Cubitene
Languages : en
Pages : 256
Book Description
Publisher:
ISBN:
Category : Cubitene
Languages : en
Pages : 256
Book Description
Chemoenzymatic and Chemical Synthesis of Enantiopure Quinoline Derivatives and Alkaloids
Author: P. L. Loke
Publisher:
ISBN:
Category :
Languages : en
Pages : 0
Book Description
Publisher:
ISBN:
Category :
Languages : en
Pages : 0
Book Description