Author: Mark A. Geyer
Publisher: Springer Science & Business Media
ISBN: 3642257577
Category : Medical
Languages : en
Pages : 456
Book Description
This volume will try to put current therapy - achievements, shortcomings, remaining medical needs - and emerging new targets into the context of increasing knowledge regarding the genetic and neurodevelopmental contributions to the pathophysiology of schizophrenia. Some of the chapters will also deal with respective experimental and clinical methodology, biomarkers, and translational aspects of drug development. The volume will concentrate on reviewing the ongoing research attempting to identify novel treatments for the cognitive deficits and negative symptoms of schizophrenia, which are not treated adequately by current antipsychotic medications.
Novel Antischizophrenia Treatments
Author: Mark A. Geyer
Publisher: Springer Science & Business Media
ISBN: 3642257577
Category : Medical
Languages : en
Pages : 456
Book Description
This volume will try to put current therapy - achievements, shortcomings, remaining medical needs - and emerging new targets into the context of increasing knowledge regarding the genetic and neurodevelopmental contributions to the pathophysiology of schizophrenia. Some of the chapters will also deal with respective experimental and clinical methodology, biomarkers, and translational aspects of drug development. The volume will concentrate on reviewing the ongoing research attempting to identify novel treatments for the cognitive deficits and negative symptoms of schizophrenia, which are not treated adequately by current antipsychotic medications.
Publisher: Springer Science & Business Media
ISBN: 3642257577
Category : Medical
Languages : en
Pages : 456
Book Description
This volume will try to put current therapy - achievements, shortcomings, remaining medical needs - and emerging new targets into the context of increasing knowledge regarding the genetic and neurodevelopmental contributions to the pathophysiology of schizophrenia. Some of the chapters will also deal with respective experimental and clinical methodology, biomarkers, and translational aspects of drug development. The volume will concentrate on reviewing the ongoing research attempting to identify novel treatments for the cognitive deficits and negative symptoms of schizophrenia, which are not treated adequately by current antipsychotic medications.
Cognitive Impairment in Schizophrenia
Author: Philip D. Harvey
Publisher: Cambridge University Press
ISBN: 1107013208
Category : Medical
Languages : en
Pages : 341
Book Description
Provides state-of-the-art information about cognition in schizophrenia with a wide ranging focus on measuring and treating cognitive deficits.
Publisher: Cambridge University Press
ISBN: 1107013208
Category : Medical
Languages : en
Pages : 341
Book Description
Provides state-of-the-art information about cognition in schizophrenia with a wide ranging focus on measuring and treating cognitive deficits.
Novel Antischizophrenia Treatments
Author: Mark A. Geyer
Publisher: Springer Science & Business Media
ISBN: 3642257585
Category : Medical
Languages : en
Pages : 456
Book Description
This volume tries to put current therapy - achievements, shortcomings, remaining medical needs - and emerging new targets into the context of increasing knowledge regarding the genetic and neurodevelopmental contributions to the pathophysiology of schizophrenia. Some of the chapters also deal with respective experimental and clinical methodology, biomarkers, and translational aspects of drug development. The volume concentrates on reviewing the ongoing research attempting to identify novel treatments for the cognitive deficits and negative symptoms of schizophrenia, which are not treated adequately by current antipsychotic medications.
Publisher: Springer Science & Business Media
ISBN: 3642257585
Category : Medical
Languages : en
Pages : 456
Book Description
This volume tries to put current therapy - achievements, shortcomings, remaining medical needs - and emerging new targets into the context of increasing knowledge regarding the genetic and neurodevelopmental contributions to the pathophysiology of schizophrenia. Some of the chapters also deal with respective experimental and clinical methodology, biomarkers, and translational aspects of drug development. The volume concentrates on reviewing the ongoing research attempting to identify novel treatments for the cognitive deficits and negative symptoms of schizophrenia, which are not treated adequately by current antipsychotic medications.
Memory and Suggestibility in the Forensic Interview
Author: Mitchell L. Eisen
Publisher: Routledge
ISBN: 1135675090
Category : Psychology
Languages : en
Pages : 535
Book Description
Memories are the ultimate foundation of testimony in legal settings ranging from criminal trials to divorce mediations and custody hearings. Yet the last decade has seen mounting evidence of various ways in which the accuracy of memories can be distorted on the one hand and enhanced on the other. This book offers a long-awaited comprehensive and balanced overview of what we now understand about children's and adults' eyewitness capabilities--and of the important practical and theoretical implications of this new understanding. The authors, leading clinicians and behavioral scientists with diverse training experiences and points of view, provide insight into the social, cognitive, developmental, and legal factors that affect the accuracy and quality of information obtained in forensic interviews. Armed with the knowledge these chapters convey, practitioners in psychology, psychiatry, social work, criminology, law, and other relevant fields will be better informed about the strengths and limitations of witnesses' accounts; researchers will be better poised to design powerful new studies. Memory and Suggestibility in the Forensic Interview will be a crucial resource for anyone involved in elucidating, interpreting, and reporting the memories of others.
Publisher: Routledge
ISBN: 1135675090
Category : Psychology
Languages : en
Pages : 535
Book Description
Memories are the ultimate foundation of testimony in legal settings ranging from criminal trials to divorce mediations and custody hearings. Yet the last decade has seen mounting evidence of various ways in which the accuracy of memories can be distorted on the one hand and enhanced on the other. This book offers a long-awaited comprehensive and balanced overview of what we now understand about children's and adults' eyewitness capabilities--and of the important practical and theoretical implications of this new understanding. The authors, leading clinicians and behavioral scientists with diverse training experiences and points of view, provide insight into the social, cognitive, developmental, and legal factors that affect the accuracy and quality of information obtained in forensic interviews. Armed with the knowledge these chapters convey, practitioners in psychology, psychiatry, social work, criminology, law, and other relevant fields will be better informed about the strengths and limitations of witnesses' accounts; researchers will be better poised to design powerful new studies. Memory and Suggestibility in the Forensic Interview will be a crucial resource for anyone involved in elucidating, interpreting, and reporting the memories of others.
Trance and Treatment
Author: Herbert Spiegel
Publisher: American Psychiatric Pub
ISBN: 1585627275
Category : Medical
Languages : en
Pages : 580
Book Description
What is hypnosis? Despite widespread misconceptions, hypnosis is not a treatment in itself; instead, it is a facilitator -- a useful diagnostic tool that can help the practitioner choose an appropriate treatment modality and accelerate various primary treatment strategies. The second edition of this remarkable work (first published 25 years ago) is written to provide both beginning and seasoned practitioners with a brief, disciplined technique for mobilizing and learning from an individual's capacity to concentrate. Putting to rest both exaggerated fears about hypnosis and overblown statements of its efficacy, this compelling volume brings scientific discipline to a systematic exploration of the clinical uses and limitations of hypnosis. The challenge was to develop a clinical measurement that could transform a fascinating amalgam of anecdotes, speculations, clinical intuitions and observations, and laboratory advances into a more fruitful and systematic body of information. Thus was born the authors' Hypnotic Induction Profile (HIP), a crucial 10-minute clinical assessment procedure that relates the spectrum of hypnotizability to personality style, psychopathology, and treatment outcome. Structured to reflect the flow of a typical evaluation and treatment session and highlighted by case examples throughout, this remarkable synthesis describes how to use the HIP, reviews relevant literature, and details principles and short- and long-term treatment strategies for smoking control; eating disorders; anxiety, concentration, and insomnia; phobias; pain control; psychosomatic disorders and conversion symptoms; trichotillomania; stuttering; and acute and posttraumatic stress disorders and dissociation. Meticulously referenced and indexed, this in-depth work concludes with an appendix on the interpretation and standardization of the HIP.This unique work stands out in the literature because It is written both as an introduction for practitioners new to hypnosis and as an in-depth guide for practitioners with wide experience in hypnosis. Unlike current clinical works, it emphasizes the importance of performing a systematic assessment of hypnotizability to identify, measure, and utilize a given patient's optimal therapeutic potential -- a process that, until now, has been relegated to clinical intuition. It describes human behavior phenomenologically as it relates to hypnosis in a probable rather than an absolute fashion. It reviews only specific portions of the literature that are particularly relevant to the important themes presented by the authors. Wherever possible, the authors apply statistical methods to test their hypotheses. The realm of scientific investigation encompassing hypnosis and psychological dysfunction is comparatively new. This exceptional volume, with its profusion of systematic data, will spark controversy and interest among scientific students of hypnosis everywhere, from psychiatrists, psychologists, and psychoanalysts to physicians, dentists, and other interested clinicians.
Publisher: American Psychiatric Pub
ISBN: 1585627275
Category : Medical
Languages : en
Pages : 580
Book Description
What is hypnosis? Despite widespread misconceptions, hypnosis is not a treatment in itself; instead, it is a facilitator -- a useful diagnostic tool that can help the practitioner choose an appropriate treatment modality and accelerate various primary treatment strategies. The second edition of this remarkable work (first published 25 years ago) is written to provide both beginning and seasoned practitioners with a brief, disciplined technique for mobilizing and learning from an individual's capacity to concentrate. Putting to rest both exaggerated fears about hypnosis and overblown statements of its efficacy, this compelling volume brings scientific discipline to a systematic exploration of the clinical uses and limitations of hypnosis. The challenge was to develop a clinical measurement that could transform a fascinating amalgam of anecdotes, speculations, clinical intuitions and observations, and laboratory advances into a more fruitful and systematic body of information. Thus was born the authors' Hypnotic Induction Profile (HIP), a crucial 10-minute clinical assessment procedure that relates the spectrum of hypnotizability to personality style, psychopathology, and treatment outcome. Structured to reflect the flow of a typical evaluation and treatment session and highlighted by case examples throughout, this remarkable synthesis describes how to use the HIP, reviews relevant literature, and details principles and short- and long-term treatment strategies for smoking control; eating disorders; anxiety, concentration, and insomnia; phobias; pain control; psychosomatic disorders and conversion symptoms; trichotillomania; stuttering; and acute and posttraumatic stress disorders and dissociation. Meticulously referenced and indexed, this in-depth work concludes with an appendix on the interpretation and standardization of the HIP.This unique work stands out in the literature because It is written both as an introduction for practitioners new to hypnosis and as an in-depth guide for practitioners with wide experience in hypnosis. Unlike current clinical works, it emphasizes the importance of performing a systematic assessment of hypnotizability to identify, measure, and utilize a given patient's optimal therapeutic potential -- a process that, until now, has been relegated to clinical intuition. It describes human behavior phenomenologically as it relates to hypnosis in a probable rather than an absolute fashion. It reviews only specific portions of the literature that are particularly relevant to the important themes presented by the authors. Wherever possible, the authors apply statistical methods to test their hypotheses. The realm of scientific investigation encompassing hypnosis and psychological dysfunction is comparatively new. This exceptional volume, with its profusion of systematic data, will spark controversy and interest among scientific students of hypnosis everywhere, from psychiatrists, psychologists, and psychoanalysts to physicians, dentists, and other interested clinicians.
Nicotine Psychopharmacology
Author: Jack E. Henningfield
Publisher: Springer Science & Business Media
ISBN: 3540692487
Category : Medical
Languages : en
Pages : 545
Book Description
The fact that tobacco ingestion can affect how people feel and think has been known for millennia, placing the plant among those used spiritually, honori?cally, and habitually (Corti 1931; Wilbert 1987). However, the conclusion that nicotine - counted for many of these psychopharmacological effects did not emerge until the nineteenth century (Langley 1905). This was elegantly described by Lewin in 1931 as follows: “The decisive factor in the effects of tobacco, desired or undesired, is nicotine. . . ”(Lewin 1998). The use of nicotine as a pharmacological probe to und- stand physiological functioning at the dawn of the twentieth century was a landmark in the birth of modern neuropharmacology (Limbird 2004; Halliwell 2007), and led the pioneering researcher John Langley to conclude that there must exist some “- ceptive substance” to explain the diverse actions of various substances, including nicotine, when applied to muscle tissue (Langley 1905). Research on tobacco and nicotine progressed throughout the twentieth century, but much of this was from a general pharmacological and toxicological rather than a psychopharmacological perspective (Larson et al. 1961). There was some attention to the effects related to addiction, such as euphoria (Johnston 1941), tolerance (Lewin 1931), and withdrawal (Finnegan et al. 1945), but outside of research supported by the tobacco industry, addiction and psychopharmacology were not major foci for research (Slade et al. 1995; Hurt and Robertson 1998; Henning?eld et al. 2006; Henning?eld and Hartel 1999; Larson et al. 1961).
Publisher: Springer Science & Business Media
ISBN: 3540692487
Category : Medical
Languages : en
Pages : 545
Book Description
The fact that tobacco ingestion can affect how people feel and think has been known for millennia, placing the plant among those used spiritually, honori?cally, and habitually (Corti 1931; Wilbert 1987). However, the conclusion that nicotine - counted for many of these psychopharmacological effects did not emerge until the nineteenth century (Langley 1905). This was elegantly described by Lewin in 1931 as follows: “The decisive factor in the effects of tobacco, desired or undesired, is nicotine. . . ”(Lewin 1998). The use of nicotine as a pharmacological probe to und- stand physiological functioning at the dawn of the twentieth century was a landmark in the birth of modern neuropharmacology (Limbird 2004; Halliwell 2007), and led the pioneering researcher John Langley to conclude that there must exist some “- ceptive substance” to explain the diverse actions of various substances, including nicotine, when applied to muscle tissue (Langley 1905). Research on tobacco and nicotine progressed throughout the twentieth century, but much of this was from a general pharmacological and toxicological rather than a psychopharmacological perspective (Larson et al. 1961). There was some attention to the effects related to addiction, such as euphoria (Johnston 1941), tolerance (Lewin 1931), and withdrawal (Finnegan et al. 1945), but outside of research supported by the tobacco industry, addiction and psychopharmacology were not major foci for research (Slade et al. 1995; Hurt and Robertson 1998; Henning?eld et al. 2006; Henning?eld and Hartel 1999; Larson et al. 1961).
Femtodynamics
Author: Ella G. Faktorovich
Publisher: SLACK Incorporated
ISBN: 9781556428623
Category : Eye
Languages : en
Pages : 270
Book Description
Femtodynamics: A Guide to Laser Settings and Procedure Techniques to Optimize Outcomes with Femtosecond Lasers is a new, comprehensive text that presents a practical approach to optimizing laser settings and procedure techniques for performing LASIK, intracorneal ring segment placement, and other corneal procedures with currently available femtosecond lasers. Dr. Ella Faktorovich has provided detailed photographs and illustrations to demonstrate the techniques for optimizing procedure outcomes. The author guides you step-by-step through common procedures while providing a detailed approach to managing and preventing possible complications. Topics covered include: - Strategies for centration - Decreasing the incidence of opaque bubble layer formation - Optimizing the energy delivered to the cornea - Improving the quality of dissection As the first book on femtosecond laser application to corneal surgery, Femtodynamics: A Guide to Laser Settings and Procedure Techniques to Optimize Outcomes with Femtosecond Lasers is a useful guide for beginning surgeons as well as surgeons looking to develop or enhance their working knowledge of femtosecond lasers.
Publisher: SLACK Incorporated
ISBN: 9781556428623
Category : Eye
Languages : en
Pages : 270
Book Description
Femtodynamics: A Guide to Laser Settings and Procedure Techniques to Optimize Outcomes with Femtosecond Lasers is a new, comprehensive text that presents a practical approach to optimizing laser settings and procedure techniques for performing LASIK, intracorneal ring segment placement, and other corneal procedures with currently available femtosecond lasers. Dr. Ella Faktorovich has provided detailed photographs and illustrations to demonstrate the techniques for optimizing procedure outcomes. The author guides you step-by-step through common procedures while providing a detailed approach to managing and preventing possible complications. Topics covered include: - Strategies for centration - Decreasing the incidence of opaque bubble layer formation - Optimizing the energy delivered to the cornea - Improving the quality of dissection As the first book on femtosecond laser application to corneal surgery, Femtodynamics: A Guide to Laser Settings and Procedure Techniques to Optimize Outcomes with Femtosecond Lasers is a useful guide for beginning surgeons as well as surgeons looking to develop or enhance their working knowledge of femtosecond lasers.
Obsessive-Compulsive Spectrum Disorders
Author: Eric Hollander
Publisher: American Psychiatric Pub
ISBN: 0890426600
Category : Medical
Languages : en
Pages : 257
Book Description
The five-year process of preparing for the revision of the Diagnostic and Statistical Manual (DSM) has been organized around a series of conferences convened by the American Psychiatric Association, in collaboration with the World Health Organization and the U.S. National Institutes of Health, to address the future of psychiatric diagnosis. Obsessive-Compulsive Spectrum Disorders: Refining the Research Agenda for DSM-V is the fruit of one of those conferences and presents the most academically sound, thought-provoking, and timely papers from the proceedings. As the conference and book demonstrate, recent advances in psychiatric diagnosis suggest a new approach to obsessive-compulsive disorder (OCD) classification: Research into the pathogenesis of OCD increasingly supports reclassification out of the anxiety disorders and into a separate group of obsessive-compulsive-related disorders (OCRDs). The relationships among OCRDs may be better defined, delineated, and understood if the current categorical diagnostic approach is supplemented with a dimensional approach which assesses obsessive-compulsive symptom domains. Obsessive-compulsive disorders are believed to be underdiagnosed in patients who complain of broad symptoms of anxiety, and reclassification of OCD as an OCRD would promote more careful examination of distinct obsessive-compulsive symptoms, yield more accurate diagnosis, and result in more effective treatments. Reclassification may facilitate future research directions in examining the biological underpinnings of these disorders. In addition to examining the genetic, neurological, and ethno-cultural bases for OCRDs, the book gives special attention to disorders that cross current diagnostic categories, including: Body dysmorphic disorder (BDD) Tourette's syndrome and trichotillomania Impulse-control disorders The process leading to publication of DSM-V is by its nature an exhaustive and complex one, and the conferences play a critical role in reviewing relevant research, assessing the status of scientific knowledge, and advancing that knowledge base. Obsessive-Compulsive Spectrum Disorders: Refining the Research Agenda for DSM-V represents the cutting-edge thinking that will culminate in new diagnoses, classifications, and standards of practice for this debilitating set of disorders. Clinicians and academicians will be fascinated by this glimpse into the next generation of the DSM-V.
Publisher: American Psychiatric Pub
ISBN: 0890426600
Category : Medical
Languages : en
Pages : 257
Book Description
The five-year process of preparing for the revision of the Diagnostic and Statistical Manual (DSM) has been organized around a series of conferences convened by the American Psychiatric Association, in collaboration with the World Health Organization and the U.S. National Institutes of Health, to address the future of psychiatric diagnosis. Obsessive-Compulsive Spectrum Disorders: Refining the Research Agenda for DSM-V is the fruit of one of those conferences and presents the most academically sound, thought-provoking, and timely papers from the proceedings. As the conference and book demonstrate, recent advances in psychiatric diagnosis suggest a new approach to obsessive-compulsive disorder (OCD) classification: Research into the pathogenesis of OCD increasingly supports reclassification out of the anxiety disorders and into a separate group of obsessive-compulsive-related disorders (OCRDs). The relationships among OCRDs may be better defined, delineated, and understood if the current categorical diagnostic approach is supplemented with a dimensional approach which assesses obsessive-compulsive symptom domains. Obsessive-compulsive disorders are believed to be underdiagnosed in patients who complain of broad symptoms of anxiety, and reclassification of OCD as an OCRD would promote more careful examination of distinct obsessive-compulsive symptoms, yield more accurate diagnosis, and result in more effective treatments. Reclassification may facilitate future research directions in examining the biological underpinnings of these disorders. In addition to examining the genetic, neurological, and ethno-cultural bases for OCRDs, the book gives special attention to disorders that cross current diagnostic categories, including: Body dysmorphic disorder (BDD) Tourette's syndrome and trichotillomania Impulse-control disorders The process leading to publication of DSM-V is by its nature an exhaustive and complex one, and the conferences play a critical role in reviewing relevant research, assessing the status of scientific knowledge, and advancing that knowledge base. Obsessive-Compulsive Spectrum Disorders: Refining the Research Agenda for DSM-V represents the cutting-edge thinking that will culminate in new diagnoses, classifications, and standards of practice for this debilitating set of disorders. Clinicians and academicians will be fascinated by this glimpse into the next generation of the DSM-V.
Time, Chance, and Reduction
Author: Gerhard Ernst
Publisher: Cambridge University Press
ISBN: 1139485431
Category : Science
Languages : en
Pages : 219
Book Description
Statistical mechanics attempts to explain the behaviour of macroscopic physical systems in terms of the mechanical properties of their constituents. Although it is one of the fundamental theories of physics, it has received little attention from philosophers of science. Nevertheless, it raises philosophical questions of fundamental importance on the nature of time, chance and reduction. Most philosophical issues in this domain relate to the question of the reduction of thermodynamics to statistical mechanics. This book addresses issues inherent in this reduction: the time-asymmetry of thermodynamics and its absence in statistical mechanics; the role and essential nature of chance and probability in this reduction when thermodynamics is non-probabilistic; and how, if at all, the reduction is possible. Compiling contributions on current research by experts in the field, this is an invaluable survey of the philosophy of statistical mechanics for academic researchers and graduate students interested in the foundations of physics.
Publisher: Cambridge University Press
ISBN: 1139485431
Category : Science
Languages : en
Pages : 219
Book Description
Statistical mechanics attempts to explain the behaviour of macroscopic physical systems in terms of the mechanical properties of their constituents. Although it is one of the fundamental theories of physics, it has received little attention from philosophers of science. Nevertheless, it raises philosophical questions of fundamental importance on the nature of time, chance and reduction. Most philosophical issues in this domain relate to the question of the reduction of thermodynamics to statistical mechanics. This book addresses issues inherent in this reduction: the time-asymmetry of thermodynamics and its absence in statistical mechanics; the role and essential nature of chance and probability in this reduction when thermodynamics is non-probabilistic; and how, if at all, the reduction is possible. Compiling contributions on current research by experts in the field, this is an invaluable survey of the philosophy of statistical mechanics for academic researchers and graduate students interested in the foundations of physics.
Toll-Like Receptors (TLRs) and Innate Immunity
Author: Stefan Bauer
Publisher: Springer Science & Business Media
ISBN: 3540721673
Category : Medical
Languages : en
Pages : 243
Book Description
Overall recent research on TLRs has led to tremendous increase in our understanding of early steps in pathogen recognition and will presumably lead to potent TLR targeting therapeutics in the future. This book reviews and highlights our recent understanding on the function and ligands of TLRs as well as their role in autoimmunity, dendritic cell activation and target structures for therapeutic intervention.
Publisher: Springer Science & Business Media
ISBN: 3540721673
Category : Medical
Languages : en
Pages : 243
Book Description
Overall recent research on TLRs has led to tremendous increase in our understanding of early steps in pathogen recognition and will presumably lead to potent TLR targeting therapeutics in the future. This book reviews and highlights our recent understanding on the function and ligands of TLRs as well as their role in autoimmunity, dendritic cell activation and target structures for therapeutic intervention.