Novel Antischizophrenia Treatments

Novel Antischizophrenia Treatments PDF Author: Mark A. Geyer
Publisher: Springer Science & Business Media
ISBN: 3642257577
Category : Medical
Languages : en
Pages : 456

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Book Description
This volume will try to put current therapy - achievements, shortcomings, remaining medical needs - and emerging new targets into the context of increasing knowledge regarding the genetic and neurodevelopmental contributions to the pathophysiology of schizophrenia. Some of the chapters will also deal with respective experimental and clinical methodology, biomarkers, and translational aspects of drug development. The volume will concentrate on reviewing the ongoing research attempting to identify novel treatments for the cognitive deficits and negative symptoms of schizophrenia, which are not treated adequately by current antipsychotic medications.

Novel Antischizophrenia Treatments

Novel Antischizophrenia Treatments PDF Author: Mark A. Geyer
Publisher: Springer Science & Business Media
ISBN: 3642257577
Category : Medical
Languages : en
Pages : 456

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Book Description
This volume will try to put current therapy - achievements, shortcomings, remaining medical needs - and emerging new targets into the context of increasing knowledge regarding the genetic and neurodevelopmental contributions to the pathophysiology of schizophrenia. Some of the chapters will also deal with respective experimental and clinical methodology, biomarkers, and translational aspects of drug development. The volume will concentrate on reviewing the ongoing research attempting to identify novel treatments for the cognitive deficits and negative symptoms of schizophrenia, which are not treated adequately by current antipsychotic medications.

Cognitive Impairment in Schizophrenia

Cognitive Impairment in Schizophrenia PDF Author: Philip D. Harvey
Publisher: Cambridge University Press
ISBN: 1107013208
Category : Medical
Languages : en
Pages : 341

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Book Description
Provides state-of-the-art information about cognition in schizophrenia with a wide ranging focus on measuring and treating cognitive deficits.

Nonsuicidal Self-Injury

Nonsuicidal Self-Injury PDF Author: E. David Klonsky
Publisher: Hogrefe Publishing GmbH
ISBN: 161334337X
Category : Psychology
Languages : en
Pages : 194

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Book Description
Nonsuicidal self-injury (NSSI) is a baffling, troubling, and hard to treat phenomenon that has increased markedly in recent years. Key issues in diagnosing and treating NSSI adequately include differentiating it from attempted suicide and other mental disorders, as well as understanding the motivations for self-injury and the context in which it occurs. This accessible and practical book provides therapists and students with a clear understanding of these key issues, as well as of suitable assessment techniques. It then goes on to delineate research-informed treatment approaches for NSSI, with an emphasis on functional assessment, emotion regulation, and problem solving, including motivational interviewing, interpersonal skills, CBT, DBT, behavioral management strategies, delay behaviors, exercise, family therapy, risk management, and medication, as well as how to successfully combine methods.

Current Antipsychotics

Current Antipsychotics PDF Author: Gerhard Gross
Publisher: Springer Science & Business Media
ISBN: 3642257615
Category : Medical
Languages : en
Pages : 423

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Book Description
Six decades after the serendipitous discovery of chlorpromazine as an antipsychotic and four decades after the launch of clozapine, the first atypical or second generation antipsychotic, psychopharmacology has arrived at an important crossroad. It is clear that pharmacological research and pharmaceutical development must now focus on complementary or even alternative mechanisms of action to address unmet medical needs, i.e. poorly treated domains of schizophrenia, improved acceptance by patients, better adherence to medication, safety in psychoses in demented patients, and avoiding cardiac and metabolic adverse effects. The first completely novel mechanisms evolving from our insights into the pathophysiology of psychotic disorders, especially the role of glutamatergic mechanisms in schizophrenia, are now under development, and further principles are on the horizon. This situation, in many respects similar to that when the initial second-generation antipsychotics became available, can be rewarding for all. Preclinical and clinical researchers now have the opportunity to confirm their hypotheses and the pharmaceutical industry may be able to develop really novel classes of therapeutics. When we were approached by the publishers of the Handbook of Experimental Pharmacology to prepare a new volume on antipsychotics, our intention was to capture both, the accumulated preclinical and clinical knowledge about current antipsychotics as well as prospects for new and potentially more specific antischizophrenia principles. These efforts should be based on the pathophysiology of the diseases and the affected neurotransmitter systems. Since preclinical research on antipsychotic compounds is only reliable when intimately linked through translational aspects to clinical results, we decided to include clinical science as well. It turned out that that this endeavor could not be covered by a single volume. We thank the editorial board and the publishers for supporting our decision to prepare two volumes: Current Antipsychotics and Novel Antischizophrenia Treatments. These topics cannot really be separated from one another and should be seen as a composite entity despite the somewhat arbitrary separation of contributions into two volumes. The continuing challenges of developing improved and safer antipsychotic medications remain of concern and are discussed in the first volume. The new opportunities for the field to develop and license adjunctive treatments for the negative symptoms and cognitive deficits that are treated inadequately by existing compounds have been incentivized recently and provide the focus for the second volume. We hope these collective contributions will facilitate the development of improved treatments for the full range of symptomatology seen in the group of schizophrenias and other major psychotic disorders. Gerhard Gross, Ludwigshafen, Germany Mark A. Geyer, La Jolla, CA This volume will try to put current therapy - achievements, shortcomings, remaining medical needs - and emerging new targets into the context of increasing knowledge regarding the genetic and neurodevelopmental contributions to the pathophysiology of schizophrenia. Some of the chapters will also deal with respective experimental and clinical methodology, biomarkers, and translational aspects of drug development. Non-schizophrenia indications will be covered to some extent, but not exhaustively.

Antibody-Drug Conjugates and Immunotoxins

Antibody-Drug Conjugates and Immunotoxins PDF Author: Gail Lewis Phillips
Publisher: Springer Science & Business Media
ISBN: 1461454565
Category : Medical
Languages : en
Pages : 370

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Book Description
This volume gathers the leading research on antibody-drug conjugates and immunotoxins. Following a rigorous overview, the volume delves into focused sections on all aspects of ADCs and ITs from clinical development through to targeted therapeutic applications and the latest technologies.

Rang & Dale's Pharmacology

Rang & Dale's Pharmacology PDF Author: James M. Ritter
Publisher: Elsevier Health Sciences
ISBN: 0702054976
Category : Medical
Languages : en
Pages : 785

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Book Description
For 25 years, Rang and Dale’s Pharmacology has delivered the core basic and clinical science information required by students and healthcare practitioners worldwide. Authors H. P. Rang, J. M. Ritter, R. J. Flower, and G. Henderson have ensured that the 8th Edition of this easy-to-read, comprehensive text continues the tradition of excellence with new coverage of drugs affecting the skin and new components online at studentconsult.com. Consult this title on your favorite e-reader. Get the essential pharmacology information you need from one authoritative source with an outstanding global reputation for excellence. Progress confidently through all relevant aspects of pharmacology, beginning with a molecular understanding of receptors and drug actions through clinical uses of key groups of drugs. Find important content quickly thanks to a color-coded layout that enables easy navigation and cross-referencing. Master difficult concepts with Key Points boxes, Clinical Uses boxes, and full-color illustrations throughout. Stay up to date with new information in the field, including an all-new chapter on drugs that affect the skin. Take advantage of new and unique features online, including 500+ chapter-specific multiple choice questions for immediate self-assessment. eBook version included! For the first time, you can access the entire book online or offline across all devices with the Student Consult eBook!

Neuropsychopharmacology of Psychosis: Relation of Brain Signals, Cognition and Chemistry

Neuropsychopharmacology of Psychosis: Relation of Brain Signals, Cognition and Chemistry PDF Author: André Schmidt
Publisher: Frontiers Media SA
ISBN: 2889193357
Category : Medicine (General)
Languages : en
Pages : 277

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Book Description
Nothing provided

Existential Psychotherapy and the Interpretation of Dreams

Existential Psychotherapy and the Interpretation of Dreams PDF Author: Clark E. Moustakas
Publisher: Jason Aronson, Incorporated
ISBN: 1461628431
Category : Psychology
Languages : en
Pages : 231

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Book Description
Existential Psychotherapy and the Interpretation of Dreams, by Clark Moustakas, presents a fresh model for the effective integration of dreamwork in humanistically oriented psychotherapy. The existential-phenomenological emphasis opens channels of conscious awareness that enable people in therapy and in everyday living to awaken to their own visions, hopes, and dreams. The internal shadows and fires of individual consciousness come to light in therapy and in dreams and invite self-resources and self-directions for change in self-growth and in significant relationships. An Existential Model is presented in detail as a guide to effective psychotherapy. With slight modification, the Model is also applicable to an understanding and interpretation of one's own dreams as well as the dreams of people who are in therapy. Through existential awareness and reflective thinking, the reader is encouraged to discover constructive challenges and paradoxes that connect dreams with waking life and lead to the discovery of creative possibilities for work and living. The existential approach to psychotherapy and dream interpretation is explicated through examples of phenomenological interviewing, use of description in lifting out horizons and core meanings, and analysis of core themes that intimately embrace the self. Existential philosophy recognizes mystery encompasses the unknown and unpredictable and asserts that regardless of past suffering and impoverishment, the potentials for health and well-being are within reach. The Existential Model offers a practical methodology and a set of guides for achieving these goals and finding a future that moves beyond the restraints and rejections that have resulted from choosing the wrong path for identity expression and selfhood. The person is the central catalyst for decision and action and retains control over her or his own destiny.

PET and SPECT in Psychiatry

PET and SPECT in Psychiatry PDF Author: Rudi A.J.O. Dierckx
Publisher: Springer Nature
ISBN: 3030572315
Category : Medical
Languages : en
Pages : 1075

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Book Description
This book provides a comprehensive overview of the use of PET and SPECT in the classic psychiatric disorders such as depression, bipolar disorder, anxiety disorders, and schizophrenia. In addition, it discusses the application of these functional neuroimaging techniques in a variety of other conditions, including sleep disorders, eating disorders, autism, and chronic fatigue syndrome. The new edition has been extensively revised and updated to reflect the latest advances and results in nuclear imaging within the field. Most chapters are written jointly by a clinical psychiatrist and a nuclear medicine expert to ensure a multidisciplinary approach. This state of the art compendium will be of value for all who have an interest in the field of neuroscience, from psychiatrists and radiologists/nuclear medicine specialists to interested general practitioners and cognitive psychologists. Companion volumes on the use of PET and SPECT in neurology and for the imaging of neurobiological systems complete a trilogy.

Chronic Mental Illness and the Changing Scope of Intervention Strategies, Diagnosis, and Treatment

Chronic Mental Illness and the Changing Scope of Intervention Strategies, Diagnosis, and Treatment PDF Author: Prasad, Barre Vijaya
Publisher: IGI Global
ISBN: 1522505202
Category : Medical
Languages : en
Pages : 435

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Book Description
Although the epidemiology of mental illnesses is innately complex, there have been many strides in the diagnosis and treatment of chronic mental illnesses as more research is being conducted in the field. As more information becomes available, mental health professionals are able to develop more effective plans for caring for their patients. Chronic Mental Illness and the Changing Scope of Intervention Strategies, Diagnosis, and Treatment examines emergent research on the identification and epidemiology of various mental illnesses. Featuring information on the prevalence of the disease, psychopharmacological advancements, and strategies for the management of chronic mental illnesses, this book is ideally suited for students, psychiatrists, psychologists, neurologists, social workers, rehabilitation therapists, and other health professionals interested in learning more about shifting practices in the mental health sector.