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Author: Jean Bignon
Publisher:
ISBN:
Category : Science
Languages : en
Pages : 556
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Book Description
What are the carcinogenic risks to the general population from environmental exposure to mineral fibers? The international contributors to this volume focus on this question, and offer the perspectives of different fields of investigation: industrial hygiene, toxicology, epidemiology, and the study of short- and long-term effects. The papers reflect the increasing concern over the potential hazard from exposure to asbestos and other fibers to individuals outside known danger areas such as industrial sites. Major emphasis is given to the problem of assessing effects of exposure to very low levels of airborn fibers and to the reliability of extrapolating risk estimates from a dose-response based on high levels of exposure. Contents include experimental data on the carcinogenic effects of mineral fibers and their mechanism of action, fiber level measurements in the lung and their correlation with air samples, methods of determining airborn levels, epidemiological data on the hazards of non-occupational exposure, and problems of risk evaluation.
Author: Jean Bignon
Publisher:
ISBN:
Category : Science
Languages : en
Pages : 556
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Book Description
What are the carcinogenic risks to the general population from environmental exposure to mineral fibers? The international contributors to this volume focus on this question, and offer the perspectives of different fields of investigation: industrial hygiene, toxicology, epidemiology, and the study of short- and long-term effects. The papers reflect the increasing concern over the potential hazard from exposure to asbestos and other fibers to individuals outside known danger areas such as industrial sites. Major emphasis is given to the problem of assessing effects of exposure to very low levels of airborn fibers and to the reliability of extrapolating risk estimates from a dose-response based on high levels of exposure. Contents include experimental data on the carcinogenic effects of mineral fibers and their mechanism of action, fiber level measurements in the lung and their correlation with air samples, methods of determining airborn levels, epidemiological data on the hazards of non-occupational exposure, and problems of risk evaluation.
Author: IARC Working Group on the Evaluation of Carcinogenic Risks to Humans
Publisher: World Health Organization
ISBN: 9283212819
Category : Medical
Languages : en
Pages : 434
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Book Description
"This publication represents the views and expert opinions of an IARC working group on the evaluation of carcinogenic risks to humans, which met in Lyon, 9-16 October 2001."
Author: International Agency for Research on Cancer Staff
Publisher:
ISBN: 9780608200354
Category :
Languages : en
Pages : 552
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Book Description
Author: F.D.K. Liddell
Publisher: CRC Press
ISBN: 9780849366468
Category : Science
Languages : en
Pages : 398
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Book Description
The part of this book covering pathogensis and modes of action begins with a chapter on the physicochemical properties of asbestos fibers and a chapter on the deposition and retention of fibers within the lung and their clearance. Some of the effects of asbestos can be reproduced in animal experiments, and the book includes a full review of the results from animal studies using various routes of administration of fibers. It is also generally accepted that the effects of fibers on pulmonary macrophages is central to all fiber-induced pathology, and the release of macrophage-associated inflammatory and immunological mediatros is dealt with in a further chapter. Examination of pathogenicity by cell culture is described, and areas covered include the role of free radicals and cellular mechanisms in producing genetic damage. The fiber-induced activation of some second messenger pathways is also described, with consideration of whether or not similar cellular mechanisms are responsible for all the clinical conditions associated with fiber exposure. Knowledge of the mechanisms involved should be valuable in the development of safe fibers and the prevention of human exposure to new materials that are dangerous as asbestos. The final chapters expound and resolve the conflicts in evidence, discuss the importance of fibers for human well-being and the possible health impact on nonmineral alternatives, and evaluate risks to the public
Author: Institute of Medicine
Publisher: National Academies Press
ISBN: 0309101697
Category : Medical
Languages : en
Pages : 341
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Book Description
In conjunction with drafting comprehensive legislation concerning compensation for health effects related to asbestos exposure (the Fairness in Asbestos Injury Act), the Senate Committee on the Judiciary directed the Institute of Medicine to assemble the Committee on Asbestos: Selected Health Effects. This committee was charged with addressing whether asbestos exposure is causally related to adverse health consequences in addition to asbestosis, mesothelioma, and lung cancer. Asbestos: Selected Cancers presents the committee's comprehensive distillation of the peer-reviewed scientific and medical literature regarding association between asbestos and colorectal, laryngeal, esophageal, pharyngeal, and stomach cancers.
Author: Committee on Nonoccupational Health Risks of Asbestiform Fibers
Publisher:
ISBN:
Category : Medical
Languages : en
Pages : 356
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Book Description
Much of the more than 30 million tons of asbestos used in the United States since 1900 is still present as insulation in offices and schools, as vinyl-asbestos flooring in homes, and in other common products. This volume presents a comprehensive evaluation of the relation of these fibers to specific diseases and the extent of nonoccupational risks associated with them. It covers sources of asbestiform fibers, properties of the fibers, and carcinogenic and fibrogenic risks they pose.
Author:
Publisher:
ISBN:
Category : Air
Languages : en
Pages : 314
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Book Description
Author: Morton Lippmann
Publisher: John Wiley & Sons
ISBN: 0470442883
Category : Science
Languages : en
Pages : 1189
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Book Description
Provides the most current information and research available for performing risk assessments on exposed individuals and populations, giving guidance to public health authorities, primary care physicians, and industrial managers Reviews current knowledge on human exposure to selected chemical agents and physical factors in the ambient environment Updates and revises the previous edition, in light of current scientific literature and its significance to public health concerns Includes new chapters on: airline cabin exposures, arsenic, endocrine disruptors, and nanoparticles
Author: George D. Guthrie, Jr.
Publisher: Walter de Gruyter GmbH & Co KG
ISBN: 1501509713
Category : Science
Languages : en
Pages : 600
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Book Description
Volume 28 of Reviews in Mineralogy provides some of the necessary tools for the researcher interested in this area of interdisciplinary research. The chapters present several of the important problems, concepts, and approaches from both the geological and biological ends of the spectrum. These two extremes are partially integrated throughout the book by cross-referencing between chapters. Chapter 1 also presents a general introduction into the ways in which these two areas overlap. However, many of the areas ripe for the interdisciplinarian will become obvious after reading the various chapters. The final chapter of this book discusses some of the regulatory aspects of minerals. Ultimately, the regulatory arena is where this type of interdisciplinary approach can make an impact, and hopefully better communication between all parties will accomplish this goal. A glossary is included at the end of this book, because the complexity of scientific terms in the two fields can thwart even the most enthusiastic of individuals. This volume represents the proceedings of a course by the same title held at Harbor House Resort and Conference Center on Nantucket Island off the coast of Massachusetts, October 22-24, 1993.
Author:
Publisher:
ISBN:
Category : Environmental health
Languages : en
Pages : 1162
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Book Description
