Author: National Research CouncilPublisher: National Academies Press
ISBN: 0309047862
Category : Science
Languages : en
Pages : 375
Book Description
The scientific basis, inference assumptions, regulatory uses, and research needs in risk assessment are considered in this two-part volume. The first part, Use of Maximum Tolerated Dose in Animal Bioassays for Carcinogenicity, focuses on whether the maximum tolerated dose should continue to be used in carcinogenesis bioassays. The committee considers several options for modifying current bioassay procedures. The second part, Two-Stage Models of Carcinogenesis, stems from efforts to identify improved means of cancer risk assessment that have resulted in the development of a mathematical dose-response model based on a paradigm for the biologic phenomena thought to be associated with carcinogenesis.
Author: 
Author: 
Author: 
Author: National Institute for Occupational Safety and Health
Author: United States. Department of Health and Human Services
Author: United States. Dept. of Health, Education, and Welfare
Author: 
Author: 
Author: United States. Congress. House. Committee on Interstate and Foreign Commerce