Author: Dinorah Gambino
Publisher: Mdpi AG
ISBN: 9783036557663
Category : Science
Languages : en
Pages : 0
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Book Description
The recognition of the exceptional chemical and biological properties of vanadium compounds has led, in recent decades, to extensive research exploring their chemistry, biochemistry, and medicinal chemistry. Due to the prospective application of vanadium compounds as therapeutic agents against diseases such as diabetes, cancer and those provoked by parasites and bacteria, vanadium coordination chemistry and biochemistry has been an area of extensive research. Currently, the most promising potential uses of vanadium compounds are as nutritional supplements and as anticancer agents potentiated by immunotherapy. Nevertheless, researchers from all over the world are dedicating their efforts to vanadium research related to other potential therapeutic applications of vanadium compounds and to obtain insights into their beneficial effects on health and their modes of action. This Special Issue collected research contributions focused on recent advances in vanadium chemistry, biochemistry, and medicinal chemistry. I expect that this collection will have a great impact on the future direction of vanadium research.
Author: Dieter Rehder
Publisher: John Wiley & Sons
ISBN: 9780470994412
Category : Science
Languages : en
Pages : 224
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Book Description
Vanadium is named after Vanadis, the most aristocratic of Norse goddesses, who symbolises beauty and fertility - essential features of vanadium chemistry. It is a ubiquitous trace element, with a surprising range of biological functions. In Bioinorganic Vanadium Chemistry, Dieter Rehder addresses the major aspects of vanadium chemistry related to living organisms and the mutual impact between biological and inorganic vanadium chemistry. Topics covered include: the history, natural occurrence, distribution and impact of vanadium inorganic aspects of the function of vanadium in biological systems interaction of aqueous vanadate and vanadyl with biogenic ligands vanadium coordination compounds the vanadium-carbon bond methods of characterisation of biogenic and model vanadium systems (EPR and ENDOR for oxovanadium(IV); 51V NMR for vanadium(V); XAS) vanadium in ascidians and polychaeta worms the concentration of vanadium in the form of amavadin by Amanita mushrooms vanadate-dependent haloperoxidases vanadium and the nitrogen cycle vanadate as energiser for bacteria, and vanadophores medicinal aspectsm including the anti-diabetic potential of vanadium compounds interaction of vanadium with proteins and protein substrates vanadium and phosphate-metabolising enzymes Bioinorganic Vanadium Chemistry conveys the essential aspects of vanadium bioinorganic chemistry, making this book a valuable complement to more general bioinorganic chemistry texts and more specialized topical reviews for researchers and students alike.
Author: Chris J Jones
Publisher: Royal Society of Chemistry
ISBN: 1847557759
Category : Science
Languages : en
Pages : 371
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Book Description
Metals in pharmaceuticals have played an increasingly important role in medicine over the last century, particularly in cancer therapy and diagnostic imaging methods. Medicinal Applications of Coordination Chemistry focuses on the role that transition metals play in clinical applications. Medicinal Applications of Coordination Chemistry begins with a brief historical review and an introduction to the chemistry of d- and f- block metals. Subsequent sections discuss metallodrugs for a number of different applications, the design of new drugs and the relationship between structure and function. Key sections include diagnostic applications of metal compounds in anatomical and functional imaging, and therapeutic applications of metals compounds. This book is ideal for researchers in academia and industry and comes complete with examples of real life applications.
Author: Katarzyna Chojnacka
Publisher: John Wiley & Sons
ISBN: 1119133777
Category : Science
Languages : en
Pages : 588
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Book Description
Comprehensive and multidisciplinary presentation of the current trends in trace elements for human, animals, plants, and the environment This reference provides the latest research into the presence, characterization, and applications of trace elements and their role in humans, animals, and plants as well as their use in developing novel, functional feeds, foods, and fertilizers. It takes an interdisciplinary approach to the subject, describing the biological and industrial applications of trace elements. It covers various topics, such as the occurrence, role, and monitoring of trace elements and their characterization, as well as applications from the preliminary research to laboratory trials. Recent Advances in Trace Elements focuses on the introduction and prospects of trace elements; tackles environmental aspects such as sources of emission, methods of monitoring, and treatment/remediation processes; goes over the biological role of trace elements in plants, animals, and human organisms; and discusses the relevance of biomedical applications and commercialization. A compendium of recent knowledge in interdisciplinary trace element research Uniquely covers production and characterization of trace elements, as well as the industrial and biomedical aspects of their use Paves the way for the development of innovative products in diverse fields, including pharmaceuticals, food, environment, and materials science Edited by well-known experts in the field of trace elements with contributions from international specialists from a wide range of areas Unique in presenting comprehensive and multidisciplinary information of the key aspects of trace elements research in a digestible form, this book is essential reading for the novice and expert in the fields of environmental science, analytical chemistry, biochemistry, materials science, pharmaceutical science, nutraceutical, and pharmaceutical sciences. It is also valuable for companies that implement new products incorporating trace elements to the market.
Author: Irena Kostova
Publisher: Bentham Science Publishers
ISBN: 9815179012
Category : Medical
Languages : en
Pages : 351
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Book Description
Explore the fascinating interplay between chemical elements and biological life with Biological and Medical Significance of Chemical Elements. This comprehensive handbook delves into the pivotal role that various chemical elements from the periodic table play in the intricate web of life processes. Discover how these elements impact human health, influence drug development, and contribute to essential biological pathways. Key Features: - Provides information on the occurrence and classification of chemical elements in nature - Explains the biological functions of elements from different main groups (including s-, p-, d- and f-block elements) - Includes information about the biomedical significance of platinum metals, lanthanides, and actinides - Includes a list of references for further reading This book serves as an indispensable resource for anyone interested in the medical biochemistry of chemical elements
Author: Robert R. Crichton
Publisher: Elsevier
ISBN: 0080556221
Category : Science
Languages : en
Pages : 383
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Book Description
The importance of metals in biology, the environment and medicine has become increasingly evident over the last twenty five years. The study of the multiple roles of metal ions in biological systems, the rapidly expanding interface between inorganic chemistry and biology constitutes the subject called Biological Inorganic Chemistry. The present text, written by a biochemist, with a long career experience in the field (particularly iron and copper) presents an introduction to this exciting and dynamic field. The book begins with introductory chapters, which together constitute an overview of the concepts, both chemical and biological, which are required to equip the reader for the detailed analysis which follows. Pathways of metal assimilation, storage and transport, as well as metal homeostasis are dealt with next. Thereafter, individual chapters discuss the roles of sodium and potassium, magnesium, calcium, zinc, iron, copper, nickel and cobalt, manganese, and finally molybdenum, vanadium, tungsten and chromium. The final three chapters provide a tantalising view of the roles of metals in brain function, biomineralization and a brief illustration of their importance in both medicine and the environment.Relaxed and agreeable writing style. The reader will not only fiind the book easy to read, the fascinating anecdotes and footnotes will give him pegs to hang important ideas on.Written by a biochemist. Will enable the reader to more readily grasp the biological and clinical relevance of the subject.Many colour illustrations. Enables easier visualization of molecular mechanismsWritten by a single author. Ensures homgeneity of style and effective cross referencing between chapters
Author: N.D. Chasteen
Publisher: Springer Science & Business Media
ISBN: 9400920237
Category : Science
Languages : en
Pages : 226
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Book Description
Over the past several decades, vanadium has increasingly attracted the interest of biologists and chemists. The discovery by Henze in 1911 that certain marine ascidians accumulate the metal in their blood cells in unusually large quantities has done much to stimulate research on the role of vanadium in biology. In the intervening years, a large number of studies have been carried out to investigate the toxicity of vanadium in higher animals and to determine whether it is an essential trace element. That vanadium is a required element for a few selected organisms is now well established. Whether vanadium is essential for humans remains unclear although evidence increasingly suggests that it probably is. The discovery by Cantley in 1977 that vanadate is a potent inhibitor of ATPases lead to numerous studies of the inhibitory and stimulatory effects of vanadium on phosphate metabolizing enzymes. As a consequence vanadates are now routinely used as probes to investigate the mechanisms of such enzymes. Our understanding of vanadium in these systems has been further enhanced by the work of Tracy and Gresser which has shown striking parallels between the chemistry of vanadates and phosphates and their biological compounds. The observation by Shechter and Karlish, and Dubyak and Kleinzeller in 1980 that vanadate is an insulin mimetic agent has opened a new area of research dealing with the hormonal effects of vanadium. The first vanadium containing enzyme, a bromoperoxidase from the marine alga Ascophyllum nodosum, was isolated in 1984 by Viltner.
Author: Shahid Ul-Islam
Publisher: John Wiley & Sons
ISBN: 1119640423
Category : Science
Languages : en
Pages : 432
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Book Description
This book is organized into 12 important chapters that focus on the progress made by metal-based drugs as anticancer, antibacterial, antiviral, anti-inflammatory, and anti-neurodegenerative agents, as well as highlights the application areas of newly discovered metallodrugs. It can prove beneficial for researchers, investigators and scientists whose work involves inorganic and coordination chemistry, medical science, pharmacy, biotechnology and biomedical engineering.
Author: James C. Dabrowiak
Publisher: John Wiley & Sons
ISBN: 1119191343
Category : Science
Languages : en
Pages : 751
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Book Description
Working from basic chemical principles, Metals in Medicine, 2nd Edition describes a wide range of metal-based agents for treating and diagnosing disease. Thoroughly revised and restructured to reflect significant research activity and advances, this new edition contains extensive updates and new pedagogical features while retaining the popular feature boxes and end-of-chapter problems of the first edition. Topics include: Metallo-Drugs and their action Platinum drugs for treating cancer Anticancer agents beyond cisplatin including ruthenium, gold, titanium and gallium Responsive Metal Complexes Treating arthritis and diabetes with metal complexes Metal complexes for killing bacteria, parasites and viruses Metal ion imbalance and its links to diseases including Alzheimer's, Wilson's and Menkes disease Metal complexes for detecting disease Nanotechnology in medicine Now in full colour, Metals in Medicine, 2nd Edition employs real-life applications and chapter-end summaries alongside feature boxes and problems. It provides a complete and methodical examination of the use of metal complexes in medicine for advanced undergraduate and postgraduate students in medicinal inorganic chemistry, bioinorganic chemistry, biochemistry, pharmacology, biophysics, biology and bioengineering. It is also an invaluable resource for academic researchers and industrial scientists in inorganic chemistry, medicinal chemistry and drug development.
Author:
Publisher:
ISBN:
Category : Chemistry
Languages : en
Pages : 934
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Book Description
