Author: Alec Sehon
Publisher: Springer Science & Business Media
ISBN: 1461558557
Category : Medical
Languages : en
Pages : 463
Book Description
One of the main attractions of research into hypersensitivity disorders is that it brings together scientists from a very broad range of disciplines. As the most common hu man immunologic disorder, it excites the interest and concern of clinicians, geneticists, basic and clinical immunologists, molecular biologists, biochemists, and physiologists. General agreement has been forged on the the pathophysiology of the disease and the mechanisms responsible for its maintenance, but many areas remain as black boxes for which we have only hypotheses. In 1992 Vienna hosted an international symposium to consider the explosion of in formation being generated by the identification, cloning, and expression of common envi ronmental allergens: The present second international conference on the MOLECULAR BIOLOGY OF ALLERGENS AND THE ATOPIC IMMUNE RESPONSE, again jointly organized and co-chaired by Professors Alec Sehon (Winnipeg) and Dietrich Kraft (Vi enna), provided an exciting opportunity for many leaders in this field to share data, argue hypotheses and seek future opportunities to enlarge our understanding of these very com plex diseases. This symposium was co-sponsored by the International Union of Immu nological Societies (I. U. I. S. ) and the International Association of Allergology and Clinical Immunology. It was held in the hospitable and comfortably elegant surroundings of Que bec City.
New Horizons in Allergy Immunotherapy
Author: Alec Sehon
Publisher: Springer Science & Business Media
ISBN: 1461558557
Category : Medical
Languages : en
Pages : 463
Book Description
One of the main attractions of research into hypersensitivity disorders is that it brings together scientists from a very broad range of disciplines. As the most common hu man immunologic disorder, it excites the interest and concern of clinicians, geneticists, basic and clinical immunologists, molecular biologists, biochemists, and physiologists. General agreement has been forged on the the pathophysiology of the disease and the mechanisms responsible for its maintenance, but many areas remain as black boxes for which we have only hypotheses. In 1992 Vienna hosted an international symposium to consider the explosion of in formation being generated by the identification, cloning, and expression of common envi ronmental allergens: The present second international conference on the MOLECULAR BIOLOGY OF ALLERGENS AND THE ATOPIC IMMUNE RESPONSE, again jointly organized and co-chaired by Professors Alec Sehon (Winnipeg) and Dietrich Kraft (Vi enna), provided an exciting opportunity for many leaders in this field to share data, argue hypotheses and seek future opportunities to enlarge our understanding of these very com plex diseases. This symposium was co-sponsored by the International Union of Immu nological Societies (I. U. I. S. ) and the International Association of Allergology and Clinical Immunology. It was held in the hospitable and comfortably elegant surroundings of Que bec City.
Publisher: Springer Science & Business Media
ISBN: 1461558557
Category : Medical
Languages : en
Pages : 463
Book Description
One of the main attractions of research into hypersensitivity disorders is that it brings together scientists from a very broad range of disciplines. As the most common hu man immunologic disorder, it excites the interest and concern of clinicians, geneticists, basic and clinical immunologists, molecular biologists, biochemists, and physiologists. General agreement has been forged on the the pathophysiology of the disease and the mechanisms responsible for its maintenance, but many areas remain as black boxes for which we have only hypotheses. In 1992 Vienna hosted an international symposium to consider the explosion of in formation being generated by the identification, cloning, and expression of common envi ronmental allergens: The present second international conference on the MOLECULAR BIOLOGY OF ALLERGENS AND THE ATOPIC IMMUNE RESPONSE, again jointly organized and co-chaired by Professors Alec Sehon (Winnipeg) and Dietrich Kraft (Vi enna), provided an exciting opportunity for many leaders in this field to share data, argue hypotheses and seek future opportunities to enlarge our understanding of these very com plex diseases. This symposium was co-sponsored by the International Union of Immu nological Societies (I. U. I. S. ) and the International Association of Allergology and Clinical Immunology. It was held in the hospitable and comfortably elegant surroundings of Que bec City.
Molecular Allergy Diagnostics
Author: Jörg Kleine-Tebbe
Publisher: Springer
ISBN: 3319424998
Category : Medical
Languages : en
Pages : 537
Book Description
This book, based on a recent German publication, offers an overview of basic data and recent developments in the groundbreaking field of molecular allergology. It comprehensively explores the origin and structure of single allergen molecules ("components") and their utility in improving the management of type I, IgE-mediated allergic reactions and disorders like allergic respiratory diseases, food allergies, and anaphylaxis. Highly specific testing, called component-resolved diagnostics, aims to identify and utilize single molecules. Over 200 single allergens from plant or animal sources have been applied to single or multiplex laboratory testing for the presence of allergen-specific IgE. This leap in assay sensitivity and specificity has led to three major advances in patient management: discrimination between primary allergic sensitization and complex cross-reactivity, recognition of IgE profiles for certain allergens and identification of patients most likely to benefit from allergen-specific immunotherapy. The book discusses in detail the benefits and limitations of this 21st century technology, and offers suggestions for the use of molecular allergology in routine clinical practice. It is a “must read” for physicians treating allergic patients as well as scientists interested in natural allergic molecules and their interactions with the human immune system.
Publisher: Springer
ISBN: 3319424998
Category : Medical
Languages : en
Pages : 537
Book Description
This book, based on a recent German publication, offers an overview of basic data and recent developments in the groundbreaking field of molecular allergology. It comprehensively explores the origin and structure of single allergen molecules ("components") and their utility in improving the management of type I, IgE-mediated allergic reactions and disorders like allergic respiratory diseases, food allergies, and anaphylaxis. Highly specific testing, called component-resolved diagnostics, aims to identify and utilize single molecules. Over 200 single allergens from plant or animal sources have been applied to single or multiplex laboratory testing for the presence of allergen-specific IgE. This leap in assay sensitivity and specificity has led to three major advances in patient management: discrimination between primary allergic sensitization and complex cross-reactivity, recognition of IgE profiles for certain allergens and identification of patients most likely to benefit from allergen-specific immunotherapy. The book discusses in detail the benefits and limitations of this 21st century technology, and offers suggestions for the use of molecular allergology in routine clinical practice. It is a “must read” for physicians treating allergic patients as well as scientists interested in natural allergic molecules and their interactions with the human immune system.
Dendritic Cells in Fundamental and Clinical Immunology
Author: Paola Ricciardi-Castagnoli
Publisher: Springer Science & Business Media
ISBN: 1475799667
Category : Medical
Languages : en
Pages : 566
Book Description
These proceedings contain selected contributions from the participants to the Fourth International Symposium on Dendritic cells that was held in Venice (Lido) Italy, from Oc tober 5 to 10, 1996. The symposium was attended by more than 500 scientists coming from 24 different countries. Studies on dendritic cells (DC) have been greatly hampered by the difficulties in preparing sufficient cell numbers and in a reasonable pure form. At this meeting it has been shown that large quantities of DC can be generated from precursors in both mice and humans, and this possibility has enormously encouraged studies aimed to characterize DC physiology and DC-specific genes, and to employ DC therapeutically as adjuvants for im munization. The possibility of generating large numbers of autologous DC that can be used in the manipulation of the immune response against cancer and infectious diseases has tremendously boosted dendritic cell research and the role of DC in a number of medi cal areas has been heatedly discussed.
Publisher: Springer Science & Business Media
ISBN: 1475799667
Category : Medical
Languages : en
Pages : 566
Book Description
These proceedings contain selected contributions from the participants to the Fourth International Symposium on Dendritic cells that was held in Venice (Lido) Italy, from Oc tober 5 to 10, 1996. The symposium was attended by more than 500 scientists coming from 24 different countries. Studies on dendritic cells (DC) have been greatly hampered by the difficulties in preparing sufficient cell numbers and in a reasonable pure form. At this meeting it has been shown that large quantities of DC can be generated from precursors in both mice and humans, and this possibility has enormously encouraged studies aimed to characterize DC physiology and DC-specific genes, and to employ DC therapeutically as adjuvants for im munization. The possibility of generating large numbers of autologous DC that can be used in the manipulation of the immune response against cancer and infectious diseases has tremendously boosted dendritic cell research and the role of DC in a number of medi cal areas has been heatedly discussed.
Platelet-Activating Factor and Related Lipid Mediators 2
Author: Santosh Nigam
Publisher: Springer Science & Business Media
ISBN: 1489901795
Category : Medical
Languages : en
Pages : 382
Book Description
In the last decade, research on platelet-activating factor (PAF) has expanded exponentially. Previous conferences on PAF in Paris, 1983, and the subsequent conferences in Gatlinburg, Ten nessee, Tokyo, Snowbird, Utah, and Berlin, at three-yearly intervals, have chronicled the devel opments in the field ofPAF. This volume records the proceedings of the Fifth International Con gress on PAF and Related Lipid Mediators, held at the Free University Medical Hospital Ben jamin Franklin in Berlin, from September 12-16, 1995. We are very much indebted to Free Uni versity Berlin for providing tremendous facilities and financial support. It was a great pleasure to have positive and generous input from the German Science Council (DFG), Bonn, Germany, and British·Biotech, Oxford, United Kingdom. Their support was crucial in making the congress a scientific success. Twenty other organizations provided additional financial support, for which we extend our deepest appreciation. The editors would like to thank all of those who participated in this congress and the authors for their contributions. The organization and planning of the Berlin Congress were carried out by an organizing committee. We gratefully acknowledge the support and assistance of the organizing commit tee members, especially Renate Nigam and Renate Roux for their untiring efforts to make the congress successful. Many colleagues also supported the congress with dedication, hard work, and expert input. We are grateful to them. We also wish to acknowledge the support of G. Sravan Kumar and Louis Kock for their efforts in producing this volume.
Publisher: Springer Science & Business Media
ISBN: 1489901795
Category : Medical
Languages : en
Pages : 382
Book Description
In the last decade, research on platelet-activating factor (PAF) has expanded exponentially. Previous conferences on PAF in Paris, 1983, and the subsequent conferences in Gatlinburg, Ten nessee, Tokyo, Snowbird, Utah, and Berlin, at three-yearly intervals, have chronicled the devel opments in the field ofPAF. This volume records the proceedings of the Fifth International Con gress on PAF and Related Lipid Mediators, held at the Free University Medical Hospital Ben jamin Franklin in Berlin, from September 12-16, 1995. We are very much indebted to Free Uni versity Berlin for providing tremendous facilities and financial support. It was a great pleasure to have positive and generous input from the German Science Council (DFG), Bonn, Germany, and British·Biotech, Oxford, United Kingdom. Their support was crucial in making the congress a scientific success. Twenty other organizations provided additional financial support, for which we extend our deepest appreciation. The editors would like to thank all of those who participated in this congress and the authors for their contributions. The organization and planning of the Berlin Congress were carried out by an organizing committee. We gratefully acknowledge the support and assistance of the organizing commit tee members, especially Renate Nigam and Renate Roux for their untiring efforts to make the congress successful. Many colleagues also supported the congress with dedication, hard work, and expert input. We are grateful to them. We also wish to acknowledge the support of G. Sravan Kumar and Louis Kock for their efforts in producing this volume.
Oxygen Transport to Tissue XVIII
Author: Edwin M. Nemoto
Publisher: Springer Science & Business Media
ISBN: 1461558654
Category : Medical
Languages : en
Pages : 584
Book Description
The 23rd annual meeting of the International Society on Oxygen Transport to Tissue took place from August 23-27, 1995, at the Station Square Sheraton along the shores of the Monongahela River where it meets with the Allegheny and Ohio Rivers to form the "Point" of the city of Pittsburgh. Pittsburgh was a convenient location for the meeting be ing between both the East and West coasts of the United States and between the Asian and European continents. It is easily accessible by air via its large international airport. In ad dition, Pittsburgh has just recently undergone a transition from the steel mills and indus tries of old to an age of computers and biotechnology as evidenced by the new Biotechnology Center of the University of Pittsburgh where a lunch and tour were pro vided for interested participants. On the tour, the participants got to see the mix of projects ranging from molecular biology to clinical projects studying membrane oxygenators, ven tricular assist devices, oxygen carriers, and more, representing the forefront of research on oxygen delivery systems to tissue.
Publisher: Springer Science & Business Media
ISBN: 1461558654
Category : Medical
Languages : en
Pages : 584
Book Description
The 23rd annual meeting of the International Society on Oxygen Transport to Tissue took place from August 23-27, 1995, at the Station Square Sheraton along the shores of the Monongahela River where it meets with the Allegheny and Ohio Rivers to form the "Point" of the city of Pittsburgh. Pittsburgh was a convenient location for the meeting be ing between both the East and West coasts of the United States and between the Asian and European continents. It is easily accessible by air via its large international airport. In ad dition, Pittsburgh has just recently undergone a transition from the steel mills and indus tries of old to an age of computers and biotechnology as evidenced by the new Biotechnology Center of the University of Pittsburgh where a lunch and tour were pro vided for interested participants. On the tour, the participants got to see the mix of projects ranging from molecular biology to clinical projects studying membrane oxygenators, ven tricular assist devices, oxygen carriers, and more, representing the forefront of research on oxygen delivery systems to tissue.
Frontiers in Arterial Chemoreception
Author: Patricio Zapata
Publisher: Springer Science & Business Media
ISBN: 1461558913
Category : Medical
Languages : en
Pages : 465
Book Description
Proceedings of the XIIIth International Symposium, held in Santiago, Chile, March 25-29, 1996
Publisher: Springer Science & Business Media
ISBN: 1461558913
Category : Medical
Languages : en
Pages : 465
Book Description
Proceedings of the XIIIth International Symposium, held in Santiago, Chile, March 25-29, 1996
Mechanisms in the Pathogenesis of Enteric Diseases
Author: Prem S. Paul
Publisher: Springer Science & Business Media
ISBN: 1489918280
Category : Medical
Languages : en
Pages : 416
Book Description
This book, Mechanisms in the Pathogenesis of Enteric Diseases, is the outcome of the First International Rushmore Conference on Mechanisms in the Pathogenesis of En teric Diseases, held in September 1995 at Rapid City, South Dakota. The meeting was or ganized by members of the North-Central Regional Research Committee "NC-62," a United States Department of Agriculture-sponsored consortium of swine enteric disease researchers from land-grant institutions. This conference was conceived as a forum for an interdisciplinary discussion of mechanisms of infectious diseases. It was intended that such a discussion would stimulate cross-fostering of ideas and nurture synergistic collabo rations among scientists working on enteric diseases of humans and animals_. In atten dance, there were more than 140 participants from the United States and 12 foreign countries representing all of the world's continents. Participants brought expertise from many disciplines in both human and veterinary medicine. Multiple perspectives and an in formal atmosphere provided an environment for lively and thought-provoking discussions. Conference topics included Pathobiology of Gastroenteric Diseases, Mechanisms of Iden tity and Interaction between Host and Pathogen, Effector Mechanisms in the Pathogenesis of Enteric Diseases, Regulation of Pathogenic Activity in Enteric Diseases, and Novel Ap proaches to Prevention and Therapy of Enteric Diseases. Ten internationally renowned scientists gave keynote presentations in addition to 30 oral presentations and 39 poster presentations. The keynote speakers were Drs.
Publisher: Springer Science & Business Media
ISBN: 1489918280
Category : Medical
Languages : en
Pages : 416
Book Description
This book, Mechanisms in the Pathogenesis of Enteric Diseases, is the outcome of the First International Rushmore Conference on Mechanisms in the Pathogenesis of En teric Diseases, held in September 1995 at Rapid City, South Dakota. The meeting was or ganized by members of the North-Central Regional Research Committee "NC-62," a United States Department of Agriculture-sponsored consortium of swine enteric disease researchers from land-grant institutions. This conference was conceived as a forum for an interdisciplinary discussion of mechanisms of infectious diseases. It was intended that such a discussion would stimulate cross-fostering of ideas and nurture synergistic collabo rations among scientists working on enteric diseases of humans and animals_. In atten dance, there were more than 140 participants from the United States and 12 foreign countries representing all of the world's continents. Participants brought expertise from many disciplines in both human and veterinary medicine. Multiple perspectives and an in formal atmosphere provided an environment for lively and thought-provoking discussions. Conference topics included Pathobiology of Gastroenteric Diseases, Mechanisms of Iden tity and Interaction between Host and Pathogen, Effector Mechanisms in the Pathogenesis of Enteric Diseases, Regulation of Pathogenic Activity in Enteric Diseases, and Novel Ap proaches to Prevention and Therapy of Enteric Diseases. Ten internationally renowned scientists gave keynote presentations in addition to 30 oral presentations and 39 poster presentations. The keynote speakers were Drs.
Eicosanoids and other Bioactive Lipids in Cancer, Inflammation, and Radiation Injury 3
Author: Kenneth V. Honn
Publisher: Springer Science & Business Media
ISBN: 1489918132
Category : Medical
Languages : en
Pages : 578
Book Description
Proceedings of the Fourth International Conference held in Hong Kong, October 4-7, 1995
Publisher: Springer Science & Business Media
ISBN: 1489918132
Category : Medical
Languages : en
Pages : 578
Book Description
Proceedings of the Fourth International Conference held in Hong Kong, October 4-7, 1995
Finding a Path to Safety in Food Allergy
Author: National Academies of Sciences, Engineering, and Medicine
Publisher: National Academies Press
ISBN: 0309450314
Category : Medical
Languages : en
Pages : 575
Book Description
Over the past 20 years, public concerns have grown in response to the apparent rising prevalence of food allergy and related atopic conditions, such as eczema. Although evidence on the true prevalence of food allergy is complicated by insufficient or inconsistent data and studies with variable methodologies, many health care experts who care for patients agree that a real increase in food allergy has occurred and that it is unlikely to be due simply to an increase in awareness and better tools for diagnosis. Many stakeholders are concerned about these increases, including the general public, policy makers, regulatory agencies, the food industry, scientists, clinicians, and especially families of children and young people suffering from food allergy. At the present time, however, despite a mounting body of data on the prevalence, health consequences, and associated costs of food allergy, this chronic disease has not garnered the level of societal attention that it warrants. Moreover, for patients and families at risk, recommendations and guidelines have not been clear about preventing exposure or the onset of reactions or for managing this disease. Finding a Path to Safety in Food Allergy examines critical issues related to food allergy, including the prevalence and severity of food allergy and its impact on affected individuals, families, and communities; and current understanding of food allergy as a disease, and in diagnostics, treatments, prevention, and public policy. This report seeks to: clarify the nature of the disease, its causes, and its current management; highlight gaps in knowledge; encourage the implementation of management tools at many levels and among many stakeholders; and delineate a roadmap to safety for those who have, or are at risk of developing, food allergy, as well as for others in society who are responsible for public health.
Publisher: National Academies Press
ISBN: 0309450314
Category : Medical
Languages : en
Pages : 575
Book Description
Over the past 20 years, public concerns have grown in response to the apparent rising prevalence of food allergy and related atopic conditions, such as eczema. Although evidence on the true prevalence of food allergy is complicated by insufficient or inconsistent data and studies with variable methodologies, many health care experts who care for patients agree that a real increase in food allergy has occurred and that it is unlikely to be due simply to an increase in awareness and better tools for diagnosis. Many stakeholders are concerned about these increases, including the general public, policy makers, regulatory agencies, the food industry, scientists, clinicians, and especially families of children and young people suffering from food allergy. At the present time, however, despite a mounting body of data on the prevalence, health consequences, and associated costs of food allergy, this chronic disease has not garnered the level of societal attention that it warrants. Moreover, for patients and families at risk, recommendations and guidelines have not been clear about preventing exposure or the onset of reactions or for managing this disease. Finding a Path to Safety in Food Allergy examines critical issues related to food allergy, including the prevalence and severity of food allergy and its impact on affected individuals, families, and communities; and current understanding of food allergy as a disease, and in diagnostics, treatments, prevention, and public policy. This report seeks to: clarify the nature of the disease, its causes, and its current management; highlight gaps in knowledge; encourage the implementation of management tools at many levels and among many stakeholders; and delineate a roadmap to safety for those who have, or are at risk of developing, food allergy, as well as for others in society who are responsible for public health.
The End of Food Allergy
Author: Kari Nadeau MD, PhD
Publisher: Penguin
ISBN: 0593189523
Category : Health & Fitness
Languages : en
Pages : 354
Book Description
A life-changing, research-based program that will end food allergies in children and adults forever. The problem of food allergy is exploding around us. But this book offers the first glimpse of hope with a powerful message: You can work with your family and your doctor to eliminate your food allergy forever. The trailblazing research of Dr. Kari Nadeau at Stanford University reveals that food allergy is not a life sentence, because the immune system can be retrained. Food allergies--from mild hives to life-threatening airway constriction--can be disrupted, slowed, and stopped. The key is a strategy called immunotherapy (IT)--the controlled, gradual reintroduction of an allergen into the body. With innovations that include state-of-the-art therapies targeting specific components of the immune system, Dr. Nadeau and her team have increased the speed and effectiveness of this treatment to a matter of months. New York Times bestselling author Sloan Barnett, the mother of two children with food allergies, provides a lay perspective that helps make Dr. Nadeau's research accessible for everyone. Together, they walk readers through every aspect of food allergy, including how to find the right treatment and how to manage the ongoing fear of allergens that haunts so many sufferers, to give us a clear, supportive plan to combat a major national and global health issue.
Publisher: Penguin
ISBN: 0593189523
Category : Health & Fitness
Languages : en
Pages : 354
Book Description
A life-changing, research-based program that will end food allergies in children and adults forever. The problem of food allergy is exploding around us. But this book offers the first glimpse of hope with a powerful message: You can work with your family and your doctor to eliminate your food allergy forever. The trailblazing research of Dr. Kari Nadeau at Stanford University reveals that food allergy is not a life sentence, because the immune system can be retrained. Food allergies--from mild hives to life-threatening airway constriction--can be disrupted, slowed, and stopped. The key is a strategy called immunotherapy (IT)--the controlled, gradual reintroduction of an allergen into the body. With innovations that include state-of-the-art therapies targeting specific components of the immune system, Dr. Nadeau and her team have increased the speed and effectiveness of this treatment to a matter of months. New York Times bestselling author Sloan Barnett, the mother of two children with food allergies, provides a lay perspective that helps make Dr. Nadeau's research accessible for everyone. Together, they walk readers through every aspect of food allergy, including how to find the right treatment and how to manage the ongoing fear of allergens that haunts so many sufferers, to give us a clear, supportive plan to combat a major national and global health issue.