New Concepts in Diagnosis and Therapy of Pancreatic Adenocarcinoma

New Concepts in Diagnosis and Therapy of Pancreatic Adenocarcinoma PDF Author: Andrea Laghi
Publisher: Springer Science & Business Media
ISBN: 3540853812
Category : Medical
Languages : en
Pages : 178

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Book Description
This book adopts a multidisciplinary approach to examine in detail a range of interesting new concepts in the diagnosis and therapy of pancreatic adenocarcinoma. It is divided into three parts. The first part provides an epidemiological and clinical overview of the disease, followed by an update on pathological findings, including new discoveries in the area of molecular biology. The second part, on diagnosis, offers detailed and comprehensive information on the advantages and disadvantages of different imaging techniques, including nuclear medicine and endoscopic ultrasound. The concluding part gives a panoramic overview of the various therapeutic options, from surgery to chemotherapy and palliative approaches based on interventional endoscopy and radiology. This book will be a valuable source of information for clinicians involved in the management of pancreatic adenocarcinoma and for all who are interested in updating their knowledge of the disease, including fellows and senior residents.

New Concepts in Diagnosis and Therapy of Pancreatic Adenocarcinoma

New Concepts in Diagnosis and Therapy of Pancreatic Adenocarcinoma PDF Author: Andrea Laghi
Publisher: Springer Science & Business Media
ISBN: 3540853812
Category : Medical
Languages : en
Pages : 178

Get Book Here

Book Description
This book adopts a multidisciplinary approach to examine in detail a range of interesting new concepts in the diagnosis and therapy of pancreatic adenocarcinoma. It is divided into three parts. The first part provides an epidemiological and clinical overview of the disease, followed by an update on pathological findings, including new discoveries in the area of molecular biology. The second part, on diagnosis, offers detailed and comprehensive information on the advantages and disadvantages of different imaging techniques, including nuclear medicine and endoscopic ultrasound. The concluding part gives a panoramic overview of the various therapeutic options, from surgery to chemotherapy and palliative approaches based on interventional endoscopy and radiology. This book will be a valuable source of information for clinicians involved in the management of pancreatic adenocarcinoma and for all who are interested in updating their knowledge of the disease, including fellows and senior residents.

Theranostic Approach for Pancreatic Cancer

Theranostic Approach for Pancreatic Cancer PDF Author: Ganji Purnachandra Nagaraju
Publisher: Academic Press
ISBN: 9780128194577
Category :
Languages : en
Pages : 420

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Book Description
Theranostic Approach for Pancreatic Cancer modulates the biologic properties of stroma in pancreatic cancer by targeting the several chemotherapy resistance mechanisms to impede their malignant property through introducing new strategies and drugs for tackling the disease. It brings information about ongoing research as well as clinical data about pancreatic cancer and provides detailed descriptions about diagnostic and therapeutic options for easy understanding. This book discusses several topics related to pancreatic cancer such as stem cells, drug resistance and pancreatic tumor microenvironment, the latest developments in chemotherapy for metastatic cancer and chemoprevention, and epigenome as a therapeutic strategy. Additionally, it encompasses a discussion on theranostic clinical applications for personalized treatment and management of pancreatic cancer. The book is a valuable resource for cancer researchers, oncologists, and several members of the biomedical field who need to understand more about the diagnosis and treatment of pancreatic cancer. Provides information on the roadblocks of chemotherapy in patients with newly diagnosed and metastatic pancreatic cancer Discusses treatment options available currently as well as prospective options for the future Focuses especially on stroma, tumor microenvironment, stem cells, stellate cells, transcription factors, growth factors, and important signaling pathways as already tested types of treatment

Current and Emerging Therapies in Pancreatic Cancer

Current and Emerging Therapies in Pancreatic Cancer PDF Author: Tanios Bekaii-Saab
Publisher: Springer
ISBN: 3319582569
Category : Medical
Languages : en
Pages : 381

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Book Description
This book provides a comprehensive, state-of-the art review of current and new therapies in treating pancreatic cancer. In addition to discussing the current landscape for treating various stages of pancreatic cancer, the text highlights several standard and emerging approaches, with a particular emphasis on novel endoscopic, surgical, chemotherapeutic, radiotherapeutic, targeted, and immunotherapeutic strategies. The volume also features concepts on the potential economic effects associated with the development and implementation of new treatments in pancreatic cancer. Written by experts from a variety of integrative disciplines, Current and Emerging Therapies in Pancreatic Cancer is a valuable resource for oncologists, gastroenterologists, surgeons, and other professionals who treat and manage patients with pancreatic cancer.

Pancreatic cancer

Pancreatic cancer PDF Author: Andrew M. Lowy
Publisher: Clinics: Surgery
ISBN: 9781437718799
Category : Medical
Languages : en
Pages : 0

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Book Description
This issue of the Surgical Oncology Clinics will cover the following topics: imaging for pancreatic cancer, EUS staging and novel therapeutics for pancreatic cancer, management of cystic tumors, management of IPMN, laparoscopic surgery for pancreatic tumors, current concepts in the surgical management of pancreatic cancer, management of borderline resectable pancreatic cancer, regionalization of pancreatic surgery, update on adjuvant trials for pancreatic cancer, neoadjuvant therapy for pancreatic cancer, novel targets for pancreatic cancer therapy, and new frontiers in pancreatic cancer.

The Heterogeneity of Cancer Metabolism

The Heterogeneity of Cancer Metabolism PDF Author: Anne Le
Publisher: Springer
ISBN: 331977736X
Category : Medical
Languages : en
Pages : 186

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Book Description
Genetic alterations in cancer, in addition to being the fundamental drivers of tumorigenesis, can give rise to a variety of metabolic adaptations that allow cancer cells to survive and proliferate in diverse tumor microenvironments. This metabolic flexibility is different from normal cellular metabolic processes and leads to heterogeneity in cancer metabolism within the same cancer type or even within the same tumor. In this book, we delve into the complexity and diversity of cancer metabolism, and highlight how understanding the heterogeneity of cancer metabolism is fundamental to the development of effective metabolism-based therapeutic strategies. Deciphering how cancer cells utilize various nutrient resources will enable clinicians and researchers to pair specific chemotherapeutic agents with patients who are most likely to respond with positive outcomes, allowing for more cost-effective and personalized cancer therapeutic strategies.

Clinical Pancreatology for Practising Gastroenterologists and Surgeons

Clinical Pancreatology for Practising Gastroenterologists and Surgeons PDF Author: Juan Enrique Dominguez-Munoz
Publisher: John Wiley & Sons
ISBN: 111957014X
Category : Medical
Languages : en
Pages : 752

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Book Description
Clinical Pancreatology Since the book Clinical Pancreatology for Practising Gastroenterologists and Surgeons was first published sixteen years ago, the knowledge and clinical management of pancreatic diseases have developed markedly. Thanks to the development of the translational research and the from bench to bedside concept, much progress from the lab has been applied to clinical practice. In addition, several highly relevant clinical trials published over the last years have resulted in the update and optimisation of clinical guidelines. A new and validated classification of severity and complications of acute pancreatitis is firmly rooted in clinical practice and has been the basis for the development of minimally invasive approaches to pancreatic necrosis. The etiopathogenic knowledge of chronic pancreatitis and other pancreatopaties, like that associated with diabetes mellitus, has developed significantly. Especially important has been the development of the field of cystic pancreatic tumours, which has been reflected in the publication of several guidelines and consensus reports over the last few years. Most research efforts have focused on pancreatic cancer, which have led and will further lead to a significant increase in the therapeutic armamentarium against this devastating disease. Finally, many newly published studies have changed the concept, causes, clinical relevance, diagnosis and treatment of exocrine pancreatic insufficiency. This new edition of Clinical Pancreatology for Practising Gastroenterologists and Surgeons has enjoyed the collaboration of the world’s leading experts in each of the areas of clinical pancreatology with the aim of facilitating gastroenterologists, surgeons, oncologists, internists, nutritionists, diabetologists, paediatricians, radiologists, pathologists and other specialists in their decision making when facing patients with pancreatic diseases in their daily clinical practice. All in all, this book supplies an indispensable update of the relevant aspects of clinical pancreatology.

Development and Evaluation of New Approaches for Fluorescence-guided Surgery and Therapy of Pancreatic Ductal Adenocarcinoma Using Orthotopic Mouse Models

Development and Evaluation of New Approaches for Fluorescence-guided Surgery and Therapy of Pancreatic Ductal Adenocarcinoma Using Orthotopic Mouse Models PDF Author: Mara Saccomano
Publisher:
ISBN:
Category :
Languages : en
Pages : 0

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Book Description
Pancreatic cancer has the poorest survival rate of the most common types of cancers with a 5 year survival rate of only 3-5% after diagnosis. Since there has been no significant improvement in the clinical outcome for several decades, there is an urgent need for novel concepts in the understanding of the pathophysiology, diagnosis and treatment of PDAC. Therefore, the aim of the study was to characterize the in vivo tumor progression and metastatic behavior of PDAC orthotopic mouse models, developing PDAC tumors with different grades of differentiation and to assess novel imaging strategies...

Pancreatic Cancer

Pancreatic Cancer PDF Author: Howard Reber
Publisher: Springer Science & Business Media
ISBN:
Category : Medical
Languages : en
Pages : 368

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Book Description
A distinguished panel of world authorities reviews the current state of today's understanding, diagnosis, and treatment of pancreatic cancer. Their cutting-edge reviews discuss both medical and surgical modalities and include numerous insights into the basic molecular processes underlying the disease. Among the key topics covered are the prospects for early diagnosis using molecular techniques, the latest diagnostic and therapeutic methods, the role of laparoscopy (diagnostic and therapeutic), and nonsurgical treatment. The reviewers also address the future possibilities for clinical advances, quality of life concerns, and the value of the Japanese "extended Whipple resection." Pancreatic Cancer will become the new standard reference for all clinicians who diagnose and treat this disease, as well as for basic scientists needing a summary of the many recent advances. i

Surgical Treatment

Surgical Treatment PDF Author: René Holzheimer
Publisher:
ISBN:
Category : Medical
Languages : en
Pages : 880

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Book Description


Diseases of the Abdomen and Pelvis 2018-2021

Diseases of the Abdomen and Pelvis 2018-2021 PDF Author: Juerg Hodler
Publisher: Springer
ISBN: 3319750194
Category : Medical
Languages : en
Pages : 262

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Book Description
This open access book deals with imaging of the abdomen and pelvis, an area that has seen considerable advances over the past several years, driven by clinical as well as technological developments. The respective chapters, written by internationally respected experts in their fields, focus on imaging diagnosis and interventional therapies in abdominal and pelvic disease; they cover all relevant imaging modalities, including magnetic resonance imaging, computed tomography, and positron emission tomography. As such, the book offers a comprehensive review of the state of the art in imaging of the abdomen and pelvis. It will be of interest to general radiologists, radiology residents, interventional radiologists, and clinicians from other specialties who want to update their knowledge in this area.