Author: Martin A. Samuels
Publisher:
ISBN: 9780781750578
Category : Medical
Languages : en
Pages :
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Book Description
The newly updated Seventh Edition of the best-selling Manual of Neurologic Therapeutics is available in PDA format for instant access at the point of care. This easy-to-navigate handheld reference provides clear, current, clinically proven recommendations for diagnosis and treatment of neurologic disorders. Users can quickly find a disease by scrolling the table of contents or index and click on icons for specific information about the disease—description, diagnosis, prognosis, and treatment. A comprehensive, up-to-date neurology drug database provides complete information about specific drugs. Platform: Palm OS, Windows CE, and Pocket PC handheld devices Also Available for iPhone/IPod touch
Author: John Noseworthy
Publisher: CRC Press
ISBN: 9781853176234
Category : Medical
Languages : en
Pages : 612
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Book Description
A comprehensive and authoritative textbook, Neurological Therapeutics: Principles and Practice provides a reference that is both authoritative and accessible for daily use. The textbook explores the issues underlying treatment decisions not only for the most readily treated disorders but also for those conditions with few existing, definitive therapeutic options. With 600 figures, 37 in full color, tables, and a companion volume that is portable and easy-to-use, the final product is an important reference.
Author: Krishnan Padmakumari Sivaraman Nair
Publisher: Cambridge University Press
ISBN: 110718469X
Category : Medical
Languages : en
Pages : 255
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Book Description
This practical handbook for clinicians covers pharmacological and non-pharmacological treatment options in neurological rehabilitation.
Author: Carlo Colosimo
Publisher: Oxford University Press, USA
ISBN: 0199862923
Category : Medical
Languages : en
Pages : 481
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Book Description
This is a practical book on neurological therapy. It is aimed at giving concise and updated answers to busy practicing clinicians in the clinic, ward, or emergency department. An evidence-based approach is used, but when there is no evidence or the data are inconclusive, an expert opinion is always given in order to meet the expectations of the reader. All neurological conditions, common and less common, are discussed; each chapter has a similar format, and contains an initial brief introduction on the epidemiology and clinical features of each disease. The therapy is then discussed, including pharmacological and non-pharmacological, with wide use of Tables & Figures. Flowcharts are also included in most of the chapters.
Author: Carl Faingold
Publisher: Academic Press
ISBN: 0124158641
Category : Medical
Languages : en
Pages : 537
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Book Description
Neuronal Networks in Brain Function, CNS Disorders, and Therapeutics, edited by two leaders in the field, offers a current and complete review of what we know about neural networks. How the brain accomplishes many of its more complex tasks can only be understood via study of neuronal network control and network interactions. Large networks can undergo major functional changes, resulting in substantially different brain function and affecting everything from learning to the potential for epilepsy. With chapters authored by experts in each topic, this book advances the understanding of: - How the brain carries out important tasks via networks - How these networks interact in normal brain function - Major mechanisms that control network function - The interaction of the normal networks to produce more complex behaviors - How brain disorders can result from abnormal interactions - How therapy of disorders can be advanced through this network approach This book will benefit neuroscience researchers and graduate students with an interest in networks, as well as clinicians in neuroscience, pharmacology, and psychiatry dealing with neurobiological disorders. - Utilizes perspectives and tools from various neuroscience subdisciplines (cellular, systems, physiologic), making the volume broadly relevant - Chapters explore normal network function and control mechanisms, with an eye to improving therapies for brain disorders - Reflects predominant disciplinary shift from an anatomical to a functional perspective of the brain - Edited work with chapters authored by leaders in the field around the globe – the broadest, most expert coverage available
Author: Rajesh Pahwa
Publisher: CRC Press
ISBN: 1841849081
Category : Medical
Languages : en
Pages : 622
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Book Description
Highly Commended, BMA Medical Book Awards 2014 This volume has long prevailed as one of the leading resources on Parkinson's disease (PD). Fully updated with practical and engaging chapters on pathology, neurochemistry, etiology, and breakthrough research, this source spans every essential topic related to the identification, assessment, and treatment of PD. Reflecting the many advances that have taken place in the management of PD, this volume promotes a multidisciplinary approach to care and supplies new sections on the latest pharmacologic, surgical, and rehabilitative therapies, as well as essential diagnostic, imaging, and nonmotor management strategies. New to this edition: • Early identification of premotor symptoms • Potential disease modification agents • Physical and occupational therapy
Author: Clévio Nóbrega
Publisher: Springer
ISBN: 3319717790
Category : Medical
Languages : en
Pages : 467
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Book Description
This book provides a cutting-edge review of polyglutamine disorders. It primarily focuses on two main aspects: (1) the mechanisms underlying the pathologies’ development and progression, and (2) the therapeutic strategies that are currently being explored to stop or delay disease progression. Polyglutamine (polyQ) disorders are a group of inherited neurodegenerative diseases with a fatal outcome that are caused by an abnormal expansion of a coding trinucleotide repeat (CAG), which is then translated in an abnormal protein with an elongated glutamine tract (Q). To date, nine polyQ disorders have been identified and described: dentatorubral-pallidoluysian atrophy (DRPLA); Huntington’s disease (HD); spinal–bulbar muscular atrophy (SBMA); and six spinocerebellar ataxias (SCA 1, 2, 3, 6, 7, and 17). The genetic basis of polyQ disorders is well established and described, and despite important advances that have opened up the possibility of generating genetic models of the disease, the mechanisms that cause neuronal degeneration are still largely unknown and there is currently no treatment available for these disorders. Further, it is believed that the different polyQ may share some mechanisms and pathways contributing to neurodegeneration and disease progression.
Author: Jeffrey S. Chamberlain
Publisher: CRC Press
ISBN: 0849374456
Category : Medical
Languages : en
Pages : 491
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Book Description
Duchenne Muscular Dystrophy (DMD) is one of the most prevalent genetic disorders of childhood and currently stands as an incurable condition. This authoritative guide provides a clear overview of the latest current and experimental approaches to the treatment of DMD and examines the clinical, genetic, and pathophysiological aspects of the disease i
Author: Bruno Colombo
Publisher: Springer Nature
ISBN: 3030235807
Category : Medical
Languages : en
Pages : 186
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Book Description
This book analyzes and discusses in detail art therapy, a specific tool used to sustain health in affective developments, rehabilitation, motor skills and cognitive functions. Art therapy is based on the assumption that the process of making art (music, dance, painting) sparks emotions and enhances brain activity. Art therapy is used to encourage personal growth, facilitate particular brain areas or activity patterns, and improve neural connectivity. Treating neurological diseases using artistic strategies offers us a unique option for engaging brain structural networks that enhance the brain’s ability to form new connections. Based on brain plasticity, art therapy has the potential to increase our repertoire for treating neurological diseases. Neural substrates are the basis of complex emotions relative to art experiences, and involve a widespread activation of cognitive and motor systems. Accordingly, art therapy has the capacity to modulate behavior, cognition, attention and movement. In this context, art therapy can offer effective tools for improving general well-being, quality of life and motivation in connection with neurological diseases. The book discusses art therapy as a potential group of techniques for the treatment of neurological disturbances and approaches the relationship between humanistic disciplines and neurology from a holistic perspective, reflecting the growing interest in this interconnection.
Author: Nicolay Ferrari
Publisher: John Wiley & Sons
ISBN: 1118537335
Category : Medical
Languages : en
Pages : 576
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Book Description
A comprehensive review of contemporary antisense oligonucleotides drugs and therapeutic principles, methods, applications, and research Oligonucleotide-based drugs, in particular antisense oligonucleotides, are part of a growing number of pharmaceutical and biotech programs progressing to treat a wide range of indications including cancer, cardiovascular, neurodegenerative, neuromuscular, and respiratory diseases, as well as other severe and rare diseases. Reviewing fundamentals and offering guidelines for drug discovery and development, this book is a practical guide covering all key aspects of this increasingly popular area of pharmacology and biotech and pharma research, from the basic science behind antisense oligonucleotides chemistry, toxicology, manufacturing, to safety assessments, the design of therapeutic protocols, to clinical experience. Antisense oligonucleotides are single strands of DNA or RNA that are complementary to a chosen sequence. While the idea of antisense oligonucleotides to target single genes dates back to the 1970's, most advances have taken place in recent years. The increasing number of antisense oligonucleotide programs in clinical development is a testament to the progress and understanding of pharmacologic, pharmacokinetic, and toxicologic properties as well as improvement in the delivery of oligonucleotides. This valuable book reviews the fundamentals of oligonucleotides, with a focus on antisense oligonucleotide drugs, and reports on the latest research underway worldwide. • Helps readers understand antisense molecules and their targets, biochemistry, and toxicity mechanisms, roles in disease, and applications for safety and therapeutics • Examines the principles, practices, and tools for scientists in both pre-clinical and clinical settings and how to apply them to antisense oligonucleotides • Provides guidelines for scientists in drug design and discovery to help improve efficiency, assessment, and the success of drug candidates • Includes interdisciplinary perspectives, from academia, industry, regulatory and from the fields of pharmacology, toxicology, biology, and medicinal chemistry Oligonucleotide-Based Drugs and Therapeutics belongs on the reference shelves of chemists, pharmaceutical scientists, chemical biologists, toxicologists and other scientists working in the pharmaceutical and biotechnology industries. It will also be a valuable resource for regulatory specialists and safety assessment professionals and an important reference for academic researchers and post-graduates interested in therapeutics, antisense therapy, and oligonucleotides.
