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Author: I. Berczi
Publisher: Elsevier
ISBN: 0080542514
Category : Science
Languages : en
Pages : 629
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Book Description
The book summarises the current understanding of the Nervous -, Endocrine and Immune systems with emphasis on shared mediators and receptors and functional interaction. In addition to the fundamental physiological and pathophysiological mechanisms, which are presented in detail, some clinically relevant subjects are also presented, such as inflammation, asthma and allergy, autoimmune disease, immunodeficiency and the acute phase response. • A comprehensive presentation of neuroimmune biology • Introduces the subject matter to the uninformed reader • Contains basic information, theoretical considerations and up-to-date clinical chapters • The clinical chapters will be helpful to practising physicians
Author: I. Berczi
Publisher: Elsevier
ISBN: 0080542514
Category : Science
Languages : en
Pages : 629
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Book Description
The book summarises the current understanding of the Nervous -, Endocrine and Immune systems with emphasis on shared mediators and receptors and functional interaction. In addition to the fundamental physiological and pathophysiological mechanisms, which are presented in detail, some clinically relevant subjects are also presented, such as inflammation, asthma and allergy, autoimmune disease, immunodeficiency and the acute phase response. • A comprehensive presentation of neuroimmune biology • Introduces the subject matter to the uninformed reader • Contains basic information, theoretical considerations and up-to-date clinical chapters • The clinical chapters will be helpful to practising physicians
Author: Carlo Perricone
Publisher: Academic Press
ISBN: 012814307X
Category : Medical
Languages : en
Pages : 728
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Book Description
The Mosaic of Autoimmunity: The Novel Factors of Autoimmune Diseases describes the multifactorial origin and diversity of expression of autoimmune diseases in humans. The term implies that different combinations of factors in autoimmunity produce varying and unique clinical pictures in a wide spectrum of autoimmune diseases. Most of the factors involved in autoimmunity can be categorized into four groups: genetic, immune defects, hormonal and environmental factors. In this book, the environmental factors are reviewed, including infectious agents, vaccines as triggers of autoimmunity, smoking and its relationship with rheumatoid arthritis, systemic lupus erythematosus, thyroid disease, multiple sclerosis and inflammatory bowel diseases. An entirely new syndrome, the autoimmune/inflammatory syndrome induced by adjuvants (ASIA), is also included, along with other diseases that are now recognized as having an autoimmune etiopathogenesis.
Author: Institute of Medicine
Publisher: National Academies Press
ISBN: 0309173183
Category : Medical
Languages : en
Pages : 722
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Book Description
Every aspect of immune function and host defense is dependent upon a proper supply and balance of nutrients. Severe malnutrition can cause significant alteration in immune response, but even subclinical deficits may be associated with an impaired immune response, and an increased risk of infection. Infectious diseases have accounted for more off-duty days during major wars than combat wounds or nonbattle injuries. Combined stressors may reduce the normal ability of soldiers to resist pathogens, increase their susceptibility to biological warfare agents, and reduce the effectiveness of vaccines intended to protect them. There is also a concern with the inappropriate use of dietary supplements. This book, one of a series, examines the impact of various types of stressors and the role of specific dietary nutrients in maintaining immune function of military personnel in the field. It reviews the impact of compromised nutrition status on immune function; the interaction of health, exercise, and stress (both physical and psychological) in immune function; and the role of nutritional supplements and newer biotechnology methods reported to enhance immune function. The first part of the book contains the committee's workshop summary and evaluation of ongoing research by Army scientists on immune status in special forces troops, responses to the Army's questions, conclusions, and recommendations. The rest of the book contains papers contributed by workshop speakers, grouped under such broad topics as an introduction to what is known about immune function, the assessment of immune function, the effect of nutrition, and the relation between the many and varied stresses encountered by military personnel and their effect on health.
Author: Maurizio Cutolo
Publisher: Wiley-Blackwell
ISBN:
Category : Medical
Languages : en
Pages : 204
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Book Description
"Volume presents manuscripts stemming from the conference entitled "4th International Conference on Neuroendocrine Immunology in Rheumatic Diseases: Translation from Basics to Clinics", held May 8-10 2009 in Genoa, Santa Margherita Ligure, Italy"--Page v.
Author: W. Savino
Publisher: Karger Medical and Scientific Publishers
ISBN: 3318060143
Category : Medical
Languages : en
Pages : 190
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Book Description
In the last decades, several in vitro and in vivo studies have revealed the existence of a very complex network between the neuroendocrine and immune system. Important molecular mechanisms underlying these interactions, in both physiological and pathological conditions, have also been described. Indeed, hormones play a pivotal role in the development and functional regulation of the immune system – both innate and acquired responses. Immune system cells present specific hormone receptors and themselves produce some hormones, thus influencing hormone secretion. More recently, the modulation of hormone secretion has been attempted for treating associated autoimmune disorders, further supporting the strong interplay between the endocrine and immune system. Distinguished experts, who have published extensively in their fields, have contributed comprehensive chapters to this volume. The focus is on the various aspects of endocrine-neuro-immune connections, providing an updated panorama - from basics to clinical applications - of current knowledge and still debated issues.
Author: Maurizio Cutolo
Publisher:
ISBN:
Category : Medical
Languages : en
Pages : 544
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Book Description
Proceedings of a September 21-23, 2001 conference. The papers in this volume examine the basic biochemical pathways from hormone metabolism to immune and inflammatory responses, as well as the effects of cytokines and glucocorticoid interactions in inflammatory diseases such as rheumatoid arthritis. Additional papers study the CNS and stress response involvement in autoimmune diseases including SLE (Systemic Lupus Erythematosus). Included are two overview articles that review the basic and clinical progress made over the past ten years in understanding and treating the rheumatic diseases.
Author: I. C. Chikanza
Publisher: Bailliere Tindall Limited
ISBN: 9780702021824
Category : Neuroendocrinology
Languages : en
Pages : 10
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Book Description
This volume covers such topics as: the immune effects of neuropeptides; the neuroendocrine immunology of rheumatoid arthritis; the endocrine aspects of paediatric rheumatic diseases; and prospects and advances in hormonal immunomodulatory therapy.
Author: Richard E. Brown
Publisher: Cambridge University Press
ISBN: 9780521426657
Category : Science
Languages : en
Pages : 434
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Book Description
This book is designed as an introductory text in neuroendocrinology; the study of the interaction between the brain and endocrine system and the influence of this on behaviour. The endocrine glands, pituitary gland and hypothalamus and their interactions and hormones are discussed. The action of steroid and thyroid hormone receptors and the regulation of target cell response to hormones is examined. The function of neuropeptides is discussed with respect to the neuroendocrine system and behaviour. The neuroimmune system and lymphokines are described and the interaction between the neuroendocrine and neuroimmune systems discussed. Finally, methods for studying hormonal influences on behaviour are outlined. Each chapter has review and essay questions designed for advanced students and honours or graduate students with a background in neuroscience, respectively.
Author: Dennis S. Charney
Publisher: Oxford University Press
ISBN: 019068142X
Category : Medical
Languages : en
Pages : 1025
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Book Description
In the years following publication of the DSM-5(R), the field of psychiatry has seen vigorous debate between the DSM's more traditional, diagnosis-oriented approach and the NIMH's more biological, dimension-based RDoC (research domain criteria) approach. Charney & Nestler's Neurobiology of Mental Illness is an authoritative foundation for translating information from the laboratory to clinical treatment, and its fifth edition extends beyond this reference function to acknowledge and examine the controversies, different camps, and thoughts on the future of psychiatric diagnosis. In this wider context, this book provides information from numerous levels of analysis, including molecular biology and genetics, cellular physiology, neuroanatomy, neuropharmacology, epidemiology, and behavior. Sections and chapters are edited and authored by experts at the top of their fields. No other book distills the basic science and underpinnings of mental disorders-and highlights practical clinical significance-to the scope and breadth of this classic text. In this edition, Section 1, which reviews the methods used to examine the biological basis of mental illness in animal and cell models and in humans, has been expanded to reflect critically important technical advances in complex genetics (including powerful sequencing technologies and related bioinformatics), epigenetics, stem cell biology, optogenetics, neural circuit functioning, cognitive neuroscience, and brain imaging. This range of established and emerging methodologies offer groundbreaking advances in our ability to study the brain as well as unique opportunities for the translation of preclinical and clinical research into badly needed breakthroughs in our therapeutic toolkit. Sections 2 through 7 cover the neurobiology and genetics of major psychiatric disorders: psychoses (including bipolar disorder), mood disorders, anxiety disorders, substance use disorders, dementias, and disorders of childhood onset. Also covered within these sections is a summary of current therapeutic approaches for these illnesses as well as the ways in which research advances are now guiding the search for new treatments. Each of these parts has been augmented in several different areas as a reflection of research progress. The last section, Section 8, reconfigured in this new edition, now focuses on diagnostic schemes for mental illness. This includes an overview of the unique challenges that remain in diagnosing these disorders given our still limited knowledge of disease etiology and pathophysiology. The section then provides reviews of DSM-5(R), which forms the basis of psychiatric diagnosis in the United States for all clinical work, and of RDoC, which provides an alternative perspective on diagnosis in heavy use in the research community. Also included are chapters on future efforts toward precision and computational psychiatry, which promise to someday align diagnosis with underlying biological abnormalities.
Author: John H. Klippel
Publisher:
ISBN: 9780912423296
Category : Health & Fitness
Languages : en
Pages : 720
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Book Description
One of the most prestigious, comprehensive texts on arthritis and related diseases, including osteoarthritis, rheumatoid arthritis, osteoporosis, lupus and more than one hundred others.
