Neural Surface Antigens

Neural Surface Antigens PDF Author: Jan Pruszak
Publisher: Academic Press
ISBN: 0128011262
Category : Science
Languages : en
Pages : 253

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Book Description
Neural Surface Antigens: From Basic Biology towards Biomedical Applications focuses on the functionalrole of surface molecules in neural development, stem cell research, and translational biomedical paradigms.With an emphasis on human and rodent model systems, this reference covers fundamentals of neural stemcell biology and flow cytometric methodology. Addressing cell biologists as well as clinicians working in theneurosciences, the book was conceived by an international panel of experts to cover a vast array of particularsurface antigen families and subtypes. It provides insight into the basic biology and functional mechanisms ofneural cell surface signaling molecules influencing mammalian development, regeneration, and treatments. Introduces early phase clinical trials of neural stem cells Outlines characterization of surface molecule expression and methods for isolation which open unprecedented opportunities for functional study, quantitation & diagnostics Highlights the role of stem cells in neural surface antigen and biomarker analysis and applications

Neural Surface Antigens

Neural Surface Antigens PDF Author: Jan Pruszak
Publisher: Academic Press
ISBN: 0128011262
Category : Science
Languages : en
Pages : 253

Get Book Here

Book Description
Neural Surface Antigens: From Basic Biology towards Biomedical Applications focuses on the functionalrole of surface molecules in neural development, stem cell research, and translational biomedical paradigms.With an emphasis on human and rodent model systems, this reference covers fundamentals of neural stemcell biology and flow cytometric methodology. Addressing cell biologists as well as clinicians working in theneurosciences, the book was conceived by an international panel of experts to cover a vast array of particularsurface antigen families and subtypes. It provides insight into the basic biology and functional mechanisms ofneural cell surface signaling molecules influencing mammalian development, regeneration, and treatments. Introduces early phase clinical trials of neural stem cells Outlines characterization of surface molecule expression and methods for isolation which open unprecedented opportunities for functional study, quantitation & diagnostics Highlights the role of stem cells in neural surface antigen and biomarker analysis and applications

˜Aœ Comprehensive Analysis of Human Neural Cell Surface Antigens

˜Aœ Comprehensive Analysis of Human Neural Cell Surface Antigens PDF Author: Vishal Menon
Publisher:
ISBN:
Category :
Languages : en
Pages :

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Book Description


Neuronal Cell-surface Antigens as Markers of Differentiation

Neuronal Cell-surface Antigens as Markers of Differentiation PDF Author: Thomas Justin Vulliamy
Publisher:
ISBN:
Category :
Languages : en
Pages : 278

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Book Description


Neuroscience and Neurotechnology of Neuronal Cell Surface Molecules in Neural Circuits

Neuroscience and Neurotechnology of Neuronal Cell Surface Molecules in Neural Circuits PDF Author: Masahito Yamagata
Publisher: Frontiers Media SA
ISBN: 2889711498
Category : Science
Languages : en
Pages : 294

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Book Description


Surface Antigens—Advances in Research and Application: 2013 Edition

Surface Antigens—Advances in Research and Application: 2013 Edition PDF Author:
Publisher: ScholarlyEditions
ISBN: 1481692771
Category : Medical
Languages : en
Pages : 125

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Book Description
Surface Antigens—Advances in Research and Application: 2013 Edition is a ScholarlyEditions™ book that delivers timely, authoritative, and comprehensive information about Cell Adhesion Molecules. The editors have built Surface Antigens—Advances in Research and Application: 2013 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Cell Adhesion Molecules in this book to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Surface Antigens—Advances in Research and Application: 2013 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

Comprehensive Cell Surface Antigen Analysis Identifies Transferrin Receptor Protein-1 (CD71) as a Negative Selection Marker for Human Neuronal Cells

Comprehensive Cell Surface Antigen Analysis Identifies Transferrin Receptor Protein-1 (CD71) as a Negative Selection Marker for Human Neuronal Cells PDF Author: Vishal Menon
Publisher:
ISBN:
Category :
Languages : en
Pages : 0

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Book Description
Abstract: Cell state-, developmental stage-, and lineage-specific combinatorial expression of cluster of differentiation (CD) molecules enables the identification of cellular subsets via multicolor flow cytometry. We describe an exhaustive characterization of neural cell types by surface antigens, exploiting human pluripotent stem cell-derived neural cell systems. Using multiwell screening approaches followed by detailed validation of expression patterns and dynamics, we exemplify a strategy for resolving cellular heterogeneity in stem cell paradigms. In addition to providing a catalog of surface antigens expressed in the neural lineage, we identified the transferrin receptor-1 (CD71) to be differentially expressed in neural stem cells and differentiated neurons. In this context, we describe a role for N-Myc proto-oncogene (MYCN) in maintaining CD71 expression in proliferating neural cells. We report that in vitro human stem cell-derived neurons lack CD71 surface expression and that the observed differential expression can be used to identify and enrich CD71− neuronal derivatives from heterogeneous cultures

Monoclonal Antibodies to Neural Antigens

Monoclonal Antibodies to Neural Antigens PDF Author: Ronald D. G. McKay
Publisher:
ISBN:
Category : Medical
Languages : en
Pages : 310

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Book Description


Molecular Biology of The Cell

Molecular Biology of The Cell PDF Author: Bruce Alberts
Publisher:
ISBN: 9780815332183
Category : Cytology
Languages : en
Pages : 0

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Book Description


Cell Surface Antigen Thy-1

Cell Surface Antigen Thy-1 PDF Author: Arnold E. Reif
Publisher: Marcel Dekker
ISBN:
Category : Antigens
Languages : en
Pages : 656

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Book Description
Contributors discuss the history of the discovery of the antigen (in 1963), its structure and peculiar distribution (appearing on both nerve and lymph cells), the genes that regulate it, its expression under various conditions, immune responses to it, mitotic triggering, suppressor T cells, and neuroimmunology (on the relationship between the nervous and lymphoid systems). The concluding chapter advances a theory that the function of Thy-1 may vary in different tissues and different species. Annotation(c) 2003 Book News, Inc., Portland, OR (booknews.com)

Brain Neurotrauma

Brain Neurotrauma PDF Author: Firas H. Kobeissy
Publisher: CRC Press
ISBN: 1466565993
Category : Medical
Languages : en
Pages : 718

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Book Description
With the contribution from more than one hundred CNS neurotrauma experts, this book provides a comprehensive and up-to-date account on the latest developments in the area of neurotrauma including biomarker studies, experimental models, diagnostic methods, and neurotherapeutic intervention strategies in brain injury research. It discusses neurotrauma mechanisms, biomarker discovery, and neurocognitive and neurobehavioral deficits. Also included are medical interventions and recent neurotherapeutics used in the area of brain injury that have been translated to the area of rehabilitation research. In addition, a section is devoted to models of milder CNS injury, including sports injuries.