Neonatal Sepsis: Current Insights and Challenges

Neonatal Sepsis: Current Insights and Challenges PDF Author: Rozeta Sokou
Publisher: Frontiers Media SA
ISBN: 2832549950
Category : Medical
Languages : en
Pages : 93

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Book Description
Despite the continuous progress in perinatal and neonatal care, sepsis is still a leading cause of morbidity and mortality in neonates accounting for approximately 15% of deaths during the neonatal period globally. Additionally, despite being a life-threatening situation, sepsis in the neonatal population, and especially in very preterm neonates, is a potential source for short- and long-term morbidity and neurodevelopmental outcomes. Initial clinical signs and symptoms of sepsis are subtle and often non-specific in neonates, representing substantial impediments to the institutionalization of an international definition for sepsis in this population. Early diagnosis of neonatal sepsis is crucial and remains a major challenge for neonatologists due to nonspecific symptoms and laboratory tests with limited diagnostic value, resulting in the empirical and non-prudent antibiotics use, a common practice in Neonatal Intensive Care Units (NICUs). Nevertheless, this practice is largely responsible for a high rate of antibiotic resistance in NICUs, a major issue for global healthcare systems, as it has been estimated that 31% of neonatal deaths related to sepsis can be attributed to antimicrobial resistance.

The Year Book of Pediatrics

The Year Book of Pediatrics PDF Author:
Publisher:
ISBN:
Category : Children
Languages : en
Pages : 426

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Book Description


Early-onset Neonatal Sepsis

Early-onset Neonatal Sepsis PDF Author: Karen D. Fairchild
Publisher:
ISBN: 9781437718553
Category : Neonatology
Languages : en
Pages : 0

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Book Description


Sepsis in Neonates and Children

Sepsis in Neonates and Children PDF Author: Luregn J. Schlapbach
Publisher: Frontiers Media SA
ISBN: 288966323X
Category : Medical
Languages : en
Pages : 261

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Book Description


Red Book

Red Book PDF Author: Larry K. Pickering
Publisher:
ISBN: 9781581107036
Category : Medical
Languages : en
Pages : 0

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Book Description
Developed by the AAP (American Academy of Pediatrics) Committee on Infectious Diseases in conjunction with the CDC (Centers for disease control), the FDA (Food and drug administration), and other leading institutions with contributions from hundreds of physicians nationwide, the newly revised and updated 2012 Red Book continues the tradition of excellence with the latest findings and clinical recommendations on the manifestations, etiology, epidemiology, diagnosis, and treatment of more than 200 childhood conditions. [Ed.].

Liver Disease in Children

Liver Disease in Children PDF Author: Frederick J. Suchy
Publisher: Cambridge University Press
ISBN: 1139464035
Category : Medical
Languages : en
Pages : 995

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Book Description
Completely revised new edition of the premier reference on pediatric liver disease. Liver Disease in Children, 3rd Edition provides authoritative coverage of every aspect of liver disease affecting infants, children, and adolescents. The book offers an integrated approach to the science and clinical practice of pediatric hepatology and charts the substantial progress in understanding and treating these diseases. Chapters are written by international experts and address the unique pathophysiology, manifestations, and management of these disorders in the pediatric population. The third edition has been thoroughly updated and features new contributions on liver development, cholestatic and autoimmune disorders, fatty liver disease, and inborn errors of metabolism. With the continued evolution of pediatric hepatology as a discipline, this text remains an essential reference for all physicians involved in the care of children with liver disease.

Infectious Disease and Pharmacology

Infectious Disease and Pharmacology PDF Author: William Benitz
Publisher: Elsevier Health Sciences
ISBN: 0323568564
Category : Medical
Languages : en
Pages : 329

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Book Description
Dr. Richard Polin's Neonatology Questions and Controversies series highlights the most challenging aspects of neonatal care, offering trustworthy guidance on up-to-date diagnostic and treatment options in the field. In each volume, renowned experts address the clinical problems of greatest concern to today's practitioners, helping you handle difficult practice issues and provide optimal, evidence-based care to every patient. - Stay fully up to date in this fast-changing field with Infectious Disease and Pharmacology, an all-new volume in the series. - Thorough, up-to-date content on the epidemiology, clinical manifestations, treatment, and outcomes for neonatal-perinatal infections, including necrotizing enterocolitis, neonatal HSV, and congenital Zika virus infection. - The latest information on dosing of antibiotics, antivirals, and antifungals. - Current coverage of therapies for neonatal gastroesophageal reflux, seizures, neuroprotection, and neonatal abstinence syndrome, as well as pharmacokinetic and pharmacogenetic considerations in neonatal care. - Consistent chapter organization to help you find information quickly and easily. - The most authoritative advice available from world-class neonatologists who share their knowledge of new trends and developments in neonatal care. Purchase each volume individually, or get the entire 7-volume set!Gastroenterology and NutritionHematology, Immunology and GeneticsHemodynamics and CardiologyInfectious Disease and Pharmacology New Volume!Nephrology and Fluid/Electrolyte PhysiologyNeurologyThe Newborn Lung

Vitamin C

Vitamin C PDF Author: Qi Chen
Publisher: CRC Press
ISBN: 0429807813
Category : Medical
Languages : en
Pages : 269

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Book Description
Vitamin C holds a unique place in scientific and cultural history. In this book, a group of leading scientific researchers describe new insights into the myriad ways vitamin C is employed during normal physiological functioning. In addition, the text provides an extensive overview of the following: the rationale for utilizing vitamin C in the clinic, updates on recent uses of vitamin C in cancer treatment through high-dose intravenous therapies, the role vitamin C plays in the treatment of sepsis and infectious disease, management of the ways vitamin C can improve stem cell differentiation, as well as vitamin C use in other important health situations. Features Includes chapters from a team of leading international scholars Reviews the history and recent research on the functions, benefits, and uses of vitamin C Focuses special attention on the way vitamin C can be used in the treatment of cancers Discusses how vitamin C can be employed against infectious disease

Handbook of Sepsis

Handbook of Sepsis PDF Author: W. Joost Wiersinga
Publisher: Springer
ISBN: 3319735063
Category : Medical
Languages : en
Pages : 264

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Book Description
This practically oriented book provides an up-to-date overview of all significant aspects of the pathogenesis of sepsis and its management, including within the intensive care unit. Readers will find information on the involvement of the coagulation and endocrine systems during sepsis and on the use of biomarkers to diagnose sepsis and allow early intervention. International clinical practice guidelines for the management of sepsis are presented, and individual chapters focus on aspects such as fluid resuscitation, vasopressor therapy, response to multiorgan failure, antimicrobial therapy, and adjunctive immunotherapy. The closing section looks forward to the coming decade, discussing novel trial designs, sepsis in low- and middle-income countries, and emerging management approaches. The book is internatio nal in scope, with contributions from leading experts worldwide. It will be of value to residents and professionals/practitioners in the fields of infectious diseases and internal medicine, as well as to GPs and medical students.

Neonatal Hematology

Neonatal Hematology PDF Author: Pedro A. de Alarcón
Publisher: Cambridge University Press
ISBN: 1108488986
Category : Medical
Languages : en
Pages : 501

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Book Description
An essential guide to the pathogenesis, diagnosis and management of hematologic problems in the neonate, covering erythrocyte disorders, leukocyte disorders, immunologic disorders and hemostatic disorders. Guidance is practical, including blood test interpretation, advice on transfusions and reference ranges for hematological values.