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Author: Bert Merton Zuckerman
Publisher:
ISBN: 9780127824017
Category : Biological models
Languages : en
Pages :
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Book Description
Author: Bert Merton Zuckerman
Publisher:
ISBN: 9780127824017
Category : Biological models
Languages : en
Pages :
Get Book Here
Book Description
Author: Bert M. Zuckerman
Publisher: Elsevier
ISBN: 1483259641
Category : Science
Languages : en
Pages : 321
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Book Description
Nematodes as Biological Models, Volume 2: Aging and Other Model Systems contains discussions on free-living nematodes as biological models for pharmacologic and toxicant testing, and for studies on gerontology and nutrition. The book presents specific chapters that cover topics on nematodes as models to study aging; nematodes as nutritional models; physiology and morphology of nematodes; and models and mechanisms on longevity and survival in nematodes. Geneticists, cell and developmental biologists, neurologists, endocrinologists, toxicologists, nutritionists, and gerontologists will find the book invaluable.
Author: David B. Dusenbery
Publisher:
ISBN:
Category : Science
Languages : en
Pages : 336
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Book Description
V. 1. Behavioral and developmental models.--v. 2. Aging and other model systems.
Author: Itamar Glazer
Publisher: CABI
ISBN: 1789248795
Category : Science
Languages : en
Pages : 386
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Book Description
Nematodes are small multicellular organisms that have been used as biological models since the 1960s. For example, Caenorhabditis elegans is a free-living nematode worm, about 1mm in length, that lives in temperate soil environments. It is made up of about 1000 cells, and has a short life cycle of only two weeks. It was the first multicellular organism to have its whole genome sequenced. The book summarizes the importance of nematodes as model organisms in the fields of genetics, developmental biology, neurobiology, pharmacology, nutrition, ecology and parasitology. Of interest to a broad audience across a wide spectrum of disciplines, this book is useful for biologists working on comparative studies to investigate biological processes across organisms; medical scientists and pharmacologists for exploration of drugs and medicine (including the use of genome editing to eliminate diseases); ecologists considering nematodes as indicators for environment changes; and parasitologists for host-parasite interactions. Many other researchers can use this book as a benchmark for the broad implications of nematology research on other aspects of science.
Author: Heinz Osiewacz
Publisher: Taylor & Francis US
ISBN: 9781402014062
Category : Science
Languages : en
Pages : 296
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Book Description
This Volume of the Series is devoted to aging at the organismic level. Different levels of organisation, ranging from single cell organisms (yeast) to humans are included. In addition to the currently most important model systems like yeast, filamentous fungi, Caenorabditis elegans, flies and mice, other systems like sponges and plants are discussed. Most importantly, research using different aging models can be expected to unravel the most important basic mechanisms of aging that are conserved in all species. In addition, a critical discussion of what can be expected from this kind of strategy for the understanding of aging in humans is included. This book serves as excellent reading for graduate students, scientists in Medical Research, Medical doctors, researchers in pharmacological fields, researchers, biologists, and experts of this area.
Author: Bert Merton Zuckerman
Publisher:
ISBN:
Category : Science
Languages : en
Pages : 322
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Book Description
Author: National Research Council
Publisher: National Academies Press
ISBN: 0309070864
Category : Nature
Languages : en
Pages : 348
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Book Description
Scientific Frontiers in Developmental Toxicology and Risk Assessment reviews advances made during the last 10-15 years in fields such as developmental biology, molecular biology, and genetics. It describes a novel approach for how these advances might be used in combination with existing methodologies to further the understanding of mechanisms of developmental toxicity, to improve the assessment of chemicals for their ability to cause developmental toxicity, and to improve risk assessment for developmental defects. For example, based on the recent advances, even the smallest, simplest laboratory animals such as the fruit fly, roundworm, and zebrafish might be able to serve as developmental toxicological models for human biological systems. Use of such organisms might allow for rapid and inexpensive testing of large numbers of chemicals for their potential to cause developmental toxicity; presently, there are little or no developmental toxicity data available for the majority of natural and manufactured chemicals in use. This new approach to developmental toxicology and risk assessment will require simultaneous research on several fronts by experts from multiple scientific disciplines, including developmental toxicologists, developmental biologists, geneticists, epidemiologists, and biostatisticians.
Author: Caleb E. Finch
Publisher: University of Chicago Press
ISBN: 9780226248899
Category : Health & Fitness
Languages : en
Pages : 948
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Book Description
Featuring extensive references, updated for this paperback edition, Longevity, Senescence, and the Genome constitutes a landmark contribution to biomedicine and the evolutionary biology of aging. To enhance gerontology's focus on human age-related dysfunctions, Caleb E. Finch provides a comparative review of all the phyla of organisms, broadening gerontology to intersect with behavioral, developmental, evolutionary, and molecular biology. By comparing species that have different developmental and life spans, Finch proposes an original typology of senescence from rapid to gradual to negligible, and he provides the first multiphyletic calculations of mortality rate constants.
Author: Rachel A. Ankeny
Publisher: Cambridge University Press
ISBN: 110866556X
Category : Science
Languages : en
Pages : 156
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Book Description
This Element presents a philosophical exploration of the concept of the 'model organism' in contemporary biology. Thinking about model organisms enables us to examine how living organisms have been brought into the laboratory and used to gain a better understanding of biology, and to explore the research practices, commitments, and norms underlying this understanding. We contend that model organisms are key components of a distinctive way of doing research. We focus on what makes model organisms an important type of model, and how the use of these models has shaped biological knowledge, including how model organisms represent, how they are used as tools for intervention, and how the representational commitments linked to their use as models affect the research practices associated with them. This title is available as Open Access on Cambridge Core.
Author: Sean R. Gallagher
Publisher: John Wiley & Sons
ISBN: 047094241X
Category : Science
Languages : en
Pages : 679
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Book Description
The latest title from the acclaimed Current Protocols series, Current Protocols Essential Laboratory Techniques, 2e provides the new researcher with the skills and understanding of the fundamental laboratory procedures necessary to run successful experiments, solve problems, and become a productive member of the modern life science laboratory. From covering the basic skills such as measurement, preparation of reagents and use of basic instrumentation to the more advanced techniques such as blotting, chromatography and real-time PCR, this book will serve as a practical reference manual for any life science researcher. Written by a combination of distinguished investigators and outstanding faculty, Current Protocols Essential Laboratory Techniques, 2e is the cornerstone on which the beginning scientist can develop the skills for a successful research career.
