Naturally Occurring Pyrrolizidine Alkaloids PDF Download
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Author: Dr. Abdel-Fatta Rizk
Publisher: CRC Press
ISBN: 9780849346507
Category : Science
Languages : en
Pages : 244
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Book Description
Plants containing pyrrolizidine alkaloids are so numerous and widespread that they can be expected to be present in most environments. About 200 pyrrolizidine alkaloids have been isolated and identified from different plants. Interest in these alkaloids has increased in recent years due to their causative effects in the heavy loss of livestock in many countries. Naturally Occurring Pyrrolizidine Alkaloids discusses the plant sources and properties of pyrrolizidine alkaloids; extraction, fractionation and identification; various methods of spectrometry of pyrrolizidine alkaloids; quantitative determination; and the toxicity, carcinogenicity, pharmacology, and other biological activities of pyrrolizidine alkaloids. Researchers in veterinary and human medicine will find this book to be a fascinating and useful reference tool.
Author: Dr. Abdel-Fatta Rizk
Publisher: CRC Press
ISBN: 9780849346507
Category : Science
Languages : en
Pages : 244
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Book Description
Plants containing pyrrolizidine alkaloids are so numerous and widespread that they can be expected to be present in most environments. About 200 pyrrolizidine alkaloids have been isolated and identified from different plants. Interest in these alkaloids has increased in recent years due to their causative effects in the heavy loss of livestock in many countries. Naturally Occurring Pyrrolizidine Alkaloids discusses the plant sources and properties of pyrrolizidine alkaloids; extraction, fractionation and identification; various methods of spectrometry of pyrrolizidine alkaloids; quantitative determination; and the toxicity, carcinogenicity, pharmacology, and other biological activities of pyrrolizidine alkaloids. Researchers in veterinary and human medicine will find this book to be a fascinating and useful reference tool.
Author: Yiu-Chung Wong
Publisher: John Wiley & Sons
ISBN: 1118992725
Category : Technology & Engineering
Languages : en
Pages : 790
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Book Description
Analysis of Food Toxins and Toxicants consists of five sections, providing up-to-date descriptions of the analytical approaches used to detect a range of food toxins. Part I reviews the recent developments in analytical technology including sample pre-treatment and food additives. Part II covers the novel analysis of microbial and plant toxins including plant pyrrolizidine alkaloids. Part III focuses on marine toxins in fish and shellfish. Part IV discusses biogenic amines and common food toxicants, such as pesticides and heavy metals. Part V summarizes quality assurance and the recent developments in regulatory limits for toxins, toxicants and allergens, including discussions on laboratory accreditation and reference materials.
Author: Helmut Wiedenfeld
Publisher: Vandenhoeck & Ruprecht
ISBN: 3899714261
Category : Pyrrolizidines
Languages : de
Pages : 145
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Book Description
Pyrrolizidine alkaloids show only minor toxicity in their native state, but are metabolized in the human or animal organisms to carcinogenic, teratogenic and mutagenic compounds, with the precise structure of these compounds being responsible for the metabolic toxification process. Therefore, to be able to evaluate the toxic potential of each alkaloid, it is essential to exactly know the structure of the respective compound. X-ray structure analysis is the appropriate method both for elucidating the structure and for determining other parameters, such as the lengths of the bonds that influence the metabolic process. This book describes the incidence and the process of the intoxication as well as the possibilities to how the substances may reach the organism. In addition, the compounds elucidated by X-ray structure analysis to date are shown in their three-dimensional structure and structure-toxicity relationships are discussed.Pyrrolizidinalkaloide weisen in nativem Zustand nur geringe Toxizität auf, werden jedoch zu kanzerogenen, teratogenen und mutagenen Verbindungen metabolisiert, wenn sie in den menschlichen oder tierischen Organismus gelangen. Der Verlauf dieser Toxifizierung hängt von der konkreten Struktur dieser Stoffe und weiteren Parametern ab. Zur Bestimmung dieser Faktoren stellt die Röntgenstrukturanalyse die geeignete Methode dar. Im vorliegenden Buch werden das Vorkommen, der Ablauf der Toxifizierung und die Möglichkeiten, wie die Stoffe in den Organismus gelangen können, beschrieben. Es werden die bislang durch Röntgenstrukturanalyse vermessenen Verbindungen in ihrer 3D-Struktur aufgefÃ"hrt und Struktur-Toxizitätsbeziehungen diskutiert.
Author: L. B. Bull
Publisher:
ISBN:
Category : Science
Languages : en
Pages : 320
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Book Description
Author:
Publisher: Elsevier
ISBN: 0081026919
Category : Science
Languages : en
Pages : 4266
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Book Description
Comprehensive Natural Products III, Third Edition, Seven Volume Set updates and complements the previous two editions, including recent advances in cofactor chemistry, structural diversity of natural products and secondary metabolites, enzymes and enzyme mechanisms and new bioinformatics tools. Natural products research is a dynamic discipline at the intersection of chemistry and biology concerned with isolation, identification, structure elucidation, and chemical characteristics of naturally occurring compounds such as pheromones, carbohydrates, nucleic acids and enzymes. This book reviews the accumulated efforts of chemical and biological research to understand living organisms and their distinctive effects on health and medicine and to stimulate new ideas among the established natural products community. Provides readers with an in-depth review of current natural products research and a critical insight into the future direction of the field Bridges the gap in knowledge by covering developments in the field since the second edition published in 2010 Split into 7 sections on key topics to allow students, researchers and professionals to find relevant information quickly and easily Ensures that the knowledge within is easily understood by and applicable to a large audience
Author: A. R. Mattocks
Publisher:
ISBN:
Category : Medical
Languages : en
Pages : 424
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Book Description
Author: Paul F. Keusenkothen
Publisher:
ISBN:
Category :
Languages : en
Pages : 272
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Book Description
Author: John Gilbert
Publisher: John Wiley & Sons
ISBN: 1444302299
Category : Technology & Engineering
Languages : en
Pages : 432
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Book Description
Inherent toxicants and processing contaminants are bothnon-essential, bioactive substances whose levels in foods can bedifficult to control. This volume covers both types of compound forthe first time, examining their beneficial as well as theirundesirable effects in the human diet. Chapters have been writtenas individually comprehensive reviews, and topics have beenselected to illustrate recent scientific advances in understandingof the occurrence and mechanism of formation, exposure/riskassessment and developments in the underpinning analyticalmethodology. A wide range of contaminants are examined in detail,including pyrrolizidine alkaloids, glucosinolates, phycotoxins, andmycotoxins. Several process contaminants (eg acrylamide and furan),which are relatively new but which have a rapidly growingliterature, are also covered. The book provides a practical reference for a wide range ofexperts: specialist toxicologists (chemists and food chemists),hygienists, government officials and anyone who needs to be awareof the main issues concerning toxicants and process contaminants infood. It will also be a valuable introduction to the subject forpost-graduate students.
Author: Michael W. Shannon
Publisher: Saunders
ISBN: 9780721606934
Category : Drugs
Languages : en
Pages : 0
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Book Description
This edition is a reference for information related to the clinical management of children and adults whose health has been effected or potentially effected by toxic agents, including drugs, environmental threats, and natural toxins.
Author: Tadeusz Aniszewski
Publisher: Elsevier
ISBN: 0080475337
Category : Science
Languages : en
Pages : 325
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Book Description
Alkaloids, represent a group of interesting and complex chemical compounds, produced by the secondary metabolism of living organisms in different biotopes. They are relatively common chemicals in all kingdoms of living organisms in all environments. Two hundred years of scientific research has still not fully explained the connections between alkaloids and life.Alkaloids-Chemistry, Biological Significance, Applications and Ecological Role provides knowledge on structural typology, biosynthesis and metabolism in relation to recent research work on alkaloids. Considering an organic chemistry approach to alkaloids using biological and ecological explanation. Within the book several questions that persist in this field of research are approached as are some unresearched areas. The book provides beneficial text for an academic and professional audience and serves as a source of knowledge for anyone who is interested in the fascinating subject of alkaloids. Each chapter features an abstract. Appendices are included, as are a listing of alkaloids, plants containing alkaloids and some basic protocols of alkaloid analysis.* Presents the ecological role of alkaloids in nature and ecosystems * Interdisciplinary and reader friendly approach* Up-to-date knowledge
