Current Topics in Membranes and Transport

Current Topics in Membranes and Transport PDF Author:
Publisher: Academic Press
ISBN: 0080584977
Category : Science
Languages : en
Pages : 331

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Current Topics in Membranes and Transport

The Na+/H+ Exchanger

The Na+/H+ Exchanger PDF Author: Larry Fliegel
Publisher: New York : Springer
ISBN:
Category : Medical
Languages : en
Pages : 358

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Na+H+ Exchange

Na+H+ Exchange PDF Author: S. Grinstein
Publisher: CRC Press
ISBN: 1351083333
Category : Science
Languages : en
Pages : 374

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Book Description
Prepared by leading scientists in the field, these volumes compile for the first time, concise, up-to-date reviews of several aspects of the basic properties, distribution, function and regulation of the Na+/H+ antiport. In addition, current methods and the use of inhibitors and ligands for the study of the exchanger are described. These volumes are indispendable to researchers and students in the areas of ion transport, membrane biology and cellular physiology.

Current Topics in Membranes and Transport

Current Topics in Membranes and Transport PDF Author:
Publisher: Academic Press
ISBN: 0080584977
Category : Science
Languages : en
Pages : 331

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Book Description
Current Topics in Membranes and Transport

Handbook of Neurochemistry

Handbook of Neurochemistry PDF Author: Abel Lajtha
Publisher:
ISBN:
Category : Neurochemistry
Languages : en
Pages :

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Molecular Biology of the Cell

Molecular Biology of the Cell PDF Author:
Publisher:
ISBN: 9780815332183
Category : Cells
Languages : en
Pages : 0

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The Sodium-Hydrogen Exchanger

The Sodium-Hydrogen Exchanger PDF Author: Morris Karmazyn
Publisher: Springer Science & Business Media
ISBN: 1461504279
Category : Science
Languages : en
Pages : 339

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Book Description
I am extremely honored and pleased to have the opportunity to write a few introductory words for this timely volume on Na + /It exchange. This is a field of investigation that I entered into by challenge and necessity, embraced with passion and fmally left in my quest for new discoveries in growth control. Ten years, one third of my scientific life, has been devoted to uncovering the mysteries of intracellular pH (PH;) regulation with respect to growth factor action. I got started on this new topic in 1980, when I heard a rather provocative hypothesis presented by Enrique Rozengurt at an ICN-UCLA Keystone meeting on "Cell Surface and Malignancy". He showed that all mitogens induced amiloride-sensitive Na + entry into resting cells and proposed that, if a compound stimulates Na + influx, it could be a mitogen. In support of his proposal Enrique reported that the amphipathic polypeptide, mellitin, which induced Na+ influx, was indeed mitogenic for 3T3 cells. This was only correlation at this stage. However, I was fascinated by this talk. I immediately approached Enrique to inform him of my skepticism about this beautiful story, and to indicate that I would only be convinced when I succeeded in isolating mutant fibroblasts lacking the amiloride-sensitive Na+ transporter. ''Good luck!" was his response.

Anatomy and Physiology

Anatomy and Physiology PDF Author: J. Gordon Betts
Publisher:
ISBN: 9781947172807
Category :
Languages : en
Pages : 0

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Physiology of the Gastrointestinal Tract

Physiology of the Gastrointestinal Tract PDF Author: Hamid M. Said
Publisher: Academic Press
ISBN: 0128124261
Category : Medical
Languages : en
Pages : 1752

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Book Description
Physiology of the Gastrointestinal Tract, Sixth Edition, a Two-Volume set, covers the study of the mechanical, physical and biochemical functions of the GI Tract by linking clinical disease and disorder, thus bridging the gap between clinical and laboratory medicine while also covering breakthroughs in gastroenterology, such as the brain-gut axis and microbiome. Additionally, information is provided at the organism level, including animal models of gastrointestinal disorders and therapeutic possibilities. The book covers a wide range of conditions, from food allergies, constipation, chronic liver disease and IBS, also exploring emerging techniques to diagnose and normalize functions of the GI tract. As a highly referenced book, this is a useful resource for gastroenterologists, physiologists, internists, professional researchers and instructors teaching courses for clinical and research students. - Discusses the multiple processes governing gastrointestinal function - Presents new information on the brain-gut axis and microbiome - Edited by preeminent scientists in the field - Includes coverage of issues, such as food allergies, constipation, chronic liver disease, IBS, Crohn's disease, and more

The Renin-angiotensin System and Progression of Renal Diseases

The Renin-angiotensin System and Progression of Renal Diseases PDF Author: Gunter Wolf
Publisher: Karger Medical and Scientific Publishers
ISBN: 3805572751
Category : Medical
Languages : en
Pages : 278

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Book Description
The renin-angiotensin system (RAS) has long been seen as a systemic endocrine system in which angiotensin II (ANG II) is solely involved in blood pressure regulation and the mediation of aldosterone release. However, it is now known that specific organ systems exhibit their own local RAS, functioning for the most part independently from their systemic counterpart. A deluge of data from the last decade has shown that ANG II displays many more functions than just regulating blood pressure: ANG II is a growth factor, exhibits profibrogenic actions, and even serves as a proinflammatory cytokine. It is now clear that this peptide plays a pivotal role in the progression of chronic kidney disease towards endstage renal failure. Clinical studies have provided compelling evidence that interference with ANG II slows this deterioration of renal function.This publication presents the first comprehensive summary of this important topic: Basic concepts as well as clinical aspects of the RAS are reviewed by international experts who made many of the key discoveries that constitute our contemporary understanding of ANG II as a central factor in the progression of renal disease. This publication should be read by physicians treating patients with chronic renal diseases (internists, nephrologists and urologists). Moreover, basic scientists such as renal physiologists, renal pathologists and biochemists who want a comprehensive overview of the subject will profit from reading this book.

The Ischemic Heart

The Ischemic Heart PDF Author: Seibu Mochizuki
Publisher: Springer
ISBN: 0585398445
Category : Medical
Languages : en
Pages : 601

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Book Description
Over the past three decades, impressive progress in the field of pathogenesis, prevention and therapy of ischemic heart disease has resulted in a marked decline in mortality in the Western World. However, the incidence of this devastating disease is on the rise in developing countries. The Ischemic Heart is based upon a recent symposium in Tokyo on the subject. This volume is organized into two sections: (i) Pathophysiologic Mechanisms of Ischemia-Reperfusion Injury and (ii) Preconditioning and Protection of Ischemia-Reperfusion Injury, and contains up-to-date information concerning the current concepts of ischemia-reperfusion injury, the sequence of events resulting in the loss of contractile dysfunction, and mechanisms of cardioprotection by several drugs as well as the role of ischemic preconditioning in attenuating problems associated with ischemia-reperfusion injury.