Myocardial Protection by Calcium Antagonists

Myocardial Protection by Calcium Antagonists PDF Author: Lionel H. Opie
Publisher: John Wiley & Sons
ISBN: 9780471076698
Category : Medical
Languages : en
Pages : 220

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Book Description
About the Book There are vast amounts of new data emerging in the study of calcium antagonist drugs. The major issues involved are no longer just the effects of calcium antagonist drugs in angina or hypertension but their possible postinfarct protective effects, both to provide prophylaxis and to improve left ventricular function. New trials have also changed our thinking. One major trial suggested that the use of one of these agents in postinfarct patients with no history of heart failure in the acute infarct stage was not only safe but could confer positive protection from reinfarction and possibly from sudden death. Another study, also in postinfarct patients but with a different agent, has drawn attention to a further unexpected benefit, namely improvement of mechanical diastolic function. In the area of hypertension, the emphasis has shifted to the regression of left ventricular hypertrophy, now recognized as an independent risk factor for cardiovascular mortality, and to diastolic dysfunction. Looking to the future, calcium antagonists may exert protection against end-stage heart failure by limiting left ventricular hypertrophy and by vascular beneficial effects. There is emerging interest that the combination with ACE inhibitors may exert additive effects on control of hypertension and on diabetic hypertensive renal lesions. Reviews of Other Books by the Author Drugs for the Heart--"A gem" (New England Journal of Medicine) The Heart--"The subjects are brilliantly illuminated and made exciting by excellent line diagrams" (The Lancet) Angiotensin-Converting Enzyme Inhibitors: Scientific Basis for Clinical Use--"A milestone" (British Medical Journal)

Myocardial Protection by Calcium Antagonists

Myocardial Protection by Calcium Antagonists PDF Author: Lionel H. Opie
Publisher: John Wiley & Sons
ISBN: 9780471076698
Category : Medical
Languages : en
Pages : 220

Get Book Here

Book Description
About the Book There are vast amounts of new data emerging in the study of calcium antagonist drugs. The major issues involved are no longer just the effects of calcium antagonist drugs in angina or hypertension but their possible postinfarct protective effects, both to provide prophylaxis and to improve left ventricular function. New trials have also changed our thinking. One major trial suggested that the use of one of these agents in postinfarct patients with no history of heart failure in the acute infarct stage was not only safe but could confer positive protection from reinfarction and possibly from sudden death. Another study, also in postinfarct patients but with a different agent, has drawn attention to a further unexpected benefit, namely improvement of mechanical diastolic function. In the area of hypertension, the emphasis has shifted to the regression of left ventricular hypertrophy, now recognized as an independent risk factor for cardiovascular mortality, and to diastolic dysfunction. Looking to the future, calcium antagonists may exert protection against end-stage heart failure by limiting left ventricular hypertrophy and by vascular beneficial effects. There is emerging interest that the combination with ACE inhibitors may exert additive effects on control of hypertension and on diabetic hypertensive renal lesions. Reviews of Other Books by the Author Drugs for the Heart--"A gem" (New England Journal of Medicine) The Heart--"The subjects are brilliantly illuminated and made exciting by excellent line diagrams" (The Lancet) Angiotensin-Converting Enzyme Inhibitors: Scientific Basis for Clinical Use--"A milestone" (British Medical Journal)

Myocardial Protection by Calcium Antagonists

Myocardial Protection by Calcium Antagonists PDF Author: Lionel H. Opie
Publisher:
ISBN: 9780471010333
Category : Calcium
Languages : en
Pages : 195

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Book Description
Calcium-channel antagonist drugs are one of the first-line treatments for hypertension. Together with beta-blockers and nitrates, they are standard therapy for angina pectoris. This study presents clinicians with the facts needed to make informed and effective use of all the drugs in this class. The volume follows handbook format used in Opie's previous book on ACE inhibitors, and includes condensed text, tables and charts, illustrative diagrams, and selected references.

Calcium Antagonists and Myocardial Protection

Calcium Antagonists and Myocardial Protection PDF Author: Elieser Kaplinsky
Publisher:
ISBN:
Category :
Languages : en
Pages : 57

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Book Description


Calcium Antagonists and Myocardial Protection

Calcium Antagonists and Myocardial Protection PDF Author: E Kaplinsky
Publisher:
ISBN:
Category :
Languages : en
Pages :

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Book Description


Calcium Antagonists and Myocardial Protection

Calcium Antagonists and Myocardial Protection PDF Author: Elieser Kaplinsky
Publisher:
ISBN:
Category : Calcium
Languages : en
Pages : 57

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Book Description


Myocardial Protection and Calcium Antagonists

Myocardial Protection and Calcium Antagonists PDF Author: David J. Hearse
Publisher:
ISBN: 9789021998213
Category :
Languages : en
Pages : 104

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Book Description


Myocardial Protection in Regional and Global Ischemia

Myocardial Protection in Regional and Global Ischemia PDF Author:
Publisher:
ISBN:
Category :
Languages : en
Pages : 316

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Book Description


Myocardial Protection

Myocardial Protection PDF Author: Tomas A. Salerno
Publisher: John Wiley & Sons
ISBN: 1405178434
Category : Medical
Languages : en
Pages : 344

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Book Description
Myocardial protection is regarded as one of the most important, yet also most controversial aspects of cardiac surgery. There has been considerable improvement in myocardial protection strategies over recent years, utilising a variety of new approaches to treat cardiac diseases, and this text is intended to embrace the state of the art in this field. The book summarises the state of knowledge on all aspects of myocardial protection, including the latest in the treatment of cardiac diseases, robotics, pediatric surgery and the treatment of cardiac failure. Robotic surgery, valvular surgery, pediatric surgery and coronary surgery are all covered by renowned experts, producing a comprehensive, forward-looking view of the field of myocardial protection. This book should function to update physicians and surgeons interested in the field of cardiac surgery on the current state of knowledge on myocardial protection.

Calcium Antagonists

Calcium Antagonists PDF Author: T. Godfraind
Publisher: Springer Science & Business Media
ISBN: 940111725X
Category : Medical
Languages : en
Pages : 382

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Book Description
Although the importance of calcium (Ca2+) in the maintenance of cardiac contractility was recognized as early as 1880, the critical role of the ion in the contractile process in skeletal, cardiac, and smooth muscle has only been established within the last three decades. As the complexity of the pharmacological actions of the Ca2+ channel inhibitors grows, there is a continued need to further clarify the inhibitors, both chemically and functionally. This volume provides an update of the field based on the work presented at the 5th International Symposium on Calcium Antagonists: Pharmacology and Clinical Research. It reviews the current state of the growing area of molecular biology of Ca2+ channels. In the cardiovascular area, in addition to the well-established clinical uses of Ca2+ channel inhibitors, exciting new work pointing to an application in atherosclerosis is described. The book also includes important uses of Ca2+ antagonists in novel areas of interest such as the gastrointestinal tract, renal protection and multi-drug resistance.

Myocardial Protection by a Vasoselective Calcium Antagonist

Myocardial Protection by a Vasoselective Calcium Antagonist PDF Author: Yoshiyuki Haga
Publisher:
ISBN: 9789162812614
Category :
Languages : en
Pages : 35

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Book Description