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Author: Morie A. Gertz
Publisher: Springer Science & Business Media
ISBN: 1461485207
Category : Medical
Languages : en
Pages : 313
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Book Description
This is a comprehensive, state-of-the-art guide to the diagnosis, treatment, and biology of multiple myeloma and related plasma disorders. Edited and written by a multidisciplinary group of recognized authorities from the Mayo Clinic, it presents clear guidelines on diagnosis and therapy and covers all aspects of multiple myeloma, from molecular classification and diagnosis, to risk stratification and therapy. Closely related plasma cell disorders such as solitary plasmacytoma, Waldenstrom macroglobulinemia, and light chain amyloidosis are discussed in detail as well. The book addresses often overlooked topics, including the role of radiation therapy, vertebral augmentation, and supportive care. Our understanding of this group of disorders is developing at an unprecedented rate, and Multiple Myeloma meets the need among oncologists and hematologists for a clear, timely, and authoritative resource on their biology, diagnosis, and treatment.
Author: Morie A. Gertz
Publisher: Springer Science & Business Media
ISBN: 1461485207
Category : Medical
Languages : en
Pages : 313
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Book Description
This is a comprehensive, state-of-the-art guide to the diagnosis, treatment, and biology of multiple myeloma and related plasma disorders. Edited and written by a multidisciplinary group of recognized authorities from the Mayo Clinic, it presents clear guidelines on diagnosis and therapy and covers all aspects of multiple myeloma, from molecular classification and diagnosis, to risk stratification and therapy. Closely related plasma cell disorders such as solitary plasmacytoma, Waldenstrom macroglobulinemia, and light chain amyloidosis are discussed in detail as well. The book addresses often overlooked topics, including the role of radiation therapy, vertebral augmentation, and supportive care. Our understanding of this group of disorders is developing at an unprecedented rate, and Multiple Myeloma meets the need among oncologists and hematologists for a clear, timely, and authoritative resource on their biology, diagnosis, and treatment.
Author: Thomas Moehler
Publisher: Springer Science & Business Media
ISBN: 3540857729
Category : Medical
Languages : en
Pages : 349
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Book Description
Multiple myeloma is currently still an incurable disease, but during the past decade knowledge of its molecular pathogenesis has increased rapidly. This has led to remarkable progress in both diagnosis and therapy, including in particular the approval of novel and first-in-class drugs such as thalidomide, bortezomib, and lenalidomide. This book, written by internationally acknowledged experts, covers a wide range of topics relating to multiple myeloma, including history, epidemiology, pathophysiology, clinical features, staging, and prognostic systems. The principal focus, however, is on therapy, with detailed information on the various promising treatment options which give hope that this cancer will be transformed into a chronic disease or even become curable. Individualized therapy and the variety of supportive treatment options, as described in this volume, will help in achieving this goal, as well as in reducing adverse events and improving quality of life.
Author: James D. Bond
Publisher: BookLocker.com, Inc.
ISBN: 1647193869
Category : Medical
Languages : en
Pages : 135
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Book Description
James Bond's survival of multiple myeloma since 1992 is an amazing story of tenacity, hard work and good fortune. In this book Jim shares his and his caregiver wife's, Kathleen, approaches and experiences and difficulties. This book provides two acronyms Jim developed that summarize their approaches to surviving a deadly, incurable blood cancer. Multiple myeloma's average survival is about 5 years. There is no cure, yet. Jim primarily is treated in Cleveland at University Hospital's Seidman Cancer Center and the Dana Farber Cancer Institute in Boston, with second opinions from Mayo Clinic and Mass. General doctors specializing in multiple myeloma. They continue to share their story, which they have done in over 30 US states, Washing DC at the National Academy of Science, and in Canada, Spain and Japan. They welcome opportunities to help other multiple myeloma patients and caregivers by sharing their experiences. They do not give medical or drug advice in their talks nor in this book. They live in greater Cleveland, Ohio and enjoy their 2 grown boys, their wives, and 3 grandchildren. Searching Jim's name and multiple myeloma provides much of their story and contact information.
Author: Meletios A. Dimopoulos
Publisher: Springer
ISBN: 331925586X
Category : Medical
Languages : en
Pages : 245
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Book Description
This book is a comprehensive source of up-to-date information on plasma cell neoplasms. Key features include the provision of new criteria for the diagnosis of symptomatic multiple myeloma requiring treatment and the description of novel therapies for myeloma and other plasma cell neoplasms that have only very recently been licensed by the U.S. Food and Drug Administration. Examples include lenalidomide as first-line therapy, panobinostat in combination with bortezomib plus dexamethasone for relapsed/refractory myeloma, ibrutinib for Waldenström’s macroglobulinemia, and new therapeutic regimens for systemic amyloidosis and POEMS syndrome. Information is also provided on drug combinations that have shown encouraging results and are very near to approval. Other important aspects covered in the book are the role of different imaging modalities in workup and the significance of newly acquired data relating to prognosis and minimal residual disease. Readers will find Multiple Myeloma and Other Plasma Cell Neoplasms to be a rich source of knowledge that will be invaluable in improving patient management.
Author: Mohamad Mohty
Publisher: Springer
ISBN: 3319182188
Category : Medical
Languages : en
Pages : 90
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Book Description
This handbook is an in-depth and comprehensive guide to the pathophysiology, diagnosis, staging, treatment and management of patients with multiple myeloma. The Handbook was commissioned to address an unmet need for a book of this kind in the myeloma field and to provide busy healthcare professionals with an informative and educational review of the current and emerging treatment recommendations for multiple myeloma. Myeloma is a type of bone marrow cancer arising from plasma cells and is the second most common form of bone marrow cancer, but represents just 1% of all cancers. The causes of myeloma are not fully understood but it is thought to be caused by an interaction of both genetic and environmental factors. This Handbook discusses these issues as well the latest developments in the field and will be an invaluable source of topical information for all healthcare professionals with an interest in multiple myeloma.
Author: Silvia CW Ling
Publisher: Springer Nature
ISBN: 3030734404
Category : Medical
Languages : en
Pages : 154
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Book Description
Multiple Myeloma remains an incurable malignancy. As the disease progresses, it invariably becomes resistant to treatment and almost all patients develop refractory disease. There are multiple different types of targeted therapies and many of them are used in combination at different stages of disease. Targeted therapies that are approved to be used include Proteasome Inhibitors, Immunomodulatory Drugs and Monoclonal Antibodies. Second and third generations of these drugs are developed to overcome resistance and they have unique mechanism of actions. Targeted therapies that are undergoing clinical trials include CAR-T cells, bi-specific antibodies, vaccines, ubiquitin ligase inhibitors and BCL-2 inhibitors. This book will help to develop an understanding of targeted therapies in Multiple Myeloma. Its goal is to provide a unique review of the mechanism of action and resistance of the many targeted therapies in Multiple Myeloma by leaders of the field. The book will be useful for students in medical science, clinicians, health professionals, scientists, pharmaceutical professionals, drug developers, and policy makers. This book will provide an insightful knowledge of the biology of Multiple Myeloma, the mechanism of action and resistance of targeted therapies, application of biomarkers and genomics and possible strategies in overcoming resistance and future development.
Author: Tom Brokaw
Publisher: Random House
ISBN: 0679604669
Category : Biography & Autobiography
Languages : en
Pages : 256
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Book Description
NEW YORK TIMES BESTSELLER • WITH A NEW PREFACE BY THE AUTHOR • A powerful memoir of a dramatic year spent battling cancer and reflecting on a long, happy, and lucky life—from the bestselling author of The Greatest Generation, whose iconic career in journalism has spanned more than fifty years Tom Brokaw has led a fortunate life, with a strong marriage and family, many friends, and a brilliant journalism career culminating in his twenty-two years as anchor of the NBC Nightly News and as bestselling author. But in the summer of 2013, when back pain led him to the doctors at the Mayo Clinic, his run of good luck was interrupted. He received shocking news: He had multiple myeloma, a treatable but incurable blood cancer. Friends had always referred to Brokaw’s “lucky star,” but as he writes in this inspiring memoir, “Turns out that star has a dimmer switch.” Brokaw takes us through all the seasons and stages of this surprising year, the emotions, discoveries, setbacks, and struggles—times of denial, acceptance, turning points, and courage. After his diagnosis, Brokaw began to keep a journal, approaching this new stage of his life in a familiar role: as a journalist, determined to learn as much as he could about his condition, to report the story, and help others facing similar battles. That journal became the basis of this wonderfully written memoir, the story of a man coming to terms with his own mortality, contemplating what means the most to him now, and reflecting on what has meant the most to him throughout his life. Brokaw also pauses to look back on some of the important moments in his career: memories of Nelson Mandela, the Dalai Lama, the fall of the Berlin Wall, the morning of September 11, 2001, in New York City, and more. Through it all, Brokaw writes in the warm, intimate, natural voice of one of America’s most beloved journalists, giving us Brokaw on Brokaw, and bringing us with him as he navigates pain, procedures, drug regimens, and physical rehabilitation. Brokaw also writes about the importance of patients taking an active role in their own treatment, and of the vital role of caretakers and coordinated care. Generous, informative, and deeply human, A Lucky Life Interrupted offers a message of understanding and empowerment, resolve and reality, hope for the future and gratitude for a well-lived life. Praise for A Lucky Life Interrupted “It’s impossible not to be inspired by Brokaw’s story, and his willingness to share it.”—Los Angeles Times “A powerful memoir of battling cancer and facing mortality . . . Through the prism of his own illness, Brokaw looks at the larger picture of aging in America.”—Booklist (starred review) “Moving, informative and deeply personal.”—The Daily Beast “The former NBC News anchor has applied the fact-finding skills and straightforward candor that were his stock in trade during his reporting days to A Lucky Life Interrupted.”—USA Today “Brokaw doesn’t paste a smiley face on his story. Again and again, the book returns to stories of loss but also of grace, luck and the beauty of having another swing at bat.”—The Washington Post “Engaging . . . [with] the kind of insight that is typical of Mr. Brokaw’s approach to life and now to illness.”—The Wall Street Journal “Powerful and courageous . . . [Brokaw] looks ahead to the future with hope.”—Bookreporter
Author: Jim Tamkin, MD, FACP, FACE
Publisher: Springer Publishing Company
ISBN: 0826128238
Category : Health & Fitness
Languages : en
Pages : 296
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Book Description
The definitive guide to living a longer, fuller life with myeloma The Myeloma Survival Guide makes sense of the difficult questions myeloma patients face, dealing with every aspect of life after diagnosis, from creating a wellness team to navigating treatment options to building a financial safety net. Jim Tamkin, MD, who lived with myeloma for 11 years, and Dave Visel share the insights they've gained as a doctor, patient, and caregiver, including: Everything you need to know about drugs and treatments, including stem cell transplants How to deal with the pain and side effects of chemotherapy, radiation, and surgery Insurance and tax benefits to save money and get you the care you deserve Take-charge tools you can use today to feel better tomorrow The second edition has been thoroughly updated and includes a new chapter on pills and medical adherence. "An invaluable guide to patients with newly diagnosed multiple myeloma. Not only have they provided clear information on the disease and its treatment, but most importantly also convey critical guidance on how to deal with the very personal life-impacting effects of this disease for patients and family members alike." –Kenneth C. Anderson, MD, Kraft Family Professor of Medicine, Harvard Medical School, and Director, Jerome Lipper Multiple Myeloma Center and LeBow Institute for Myeloma Therapeutics, Dana-Farber Cancer Institute Jim Tamkin, MD, FACP, FACE, lived with myeloma for 11 years. He co-founded the TBA (Their Best Advice) Foundation with Dave Visel in 2009 to provide myeloma patients with the resources they need to cope with the disease. He worked as an internist and endocrinologist in Los Angeles until his death in March 2011. Dave Visel is co-founder of the TBA Foundation and author of Living with Cancer: A Practical Guide. He is a retired advertising copywriter and marketing executive, and is a caregiver to his wife, Karen, who has leukemia. They live in Los Angeles. www.TBAfoundation.org
Author: Neil S. Harris, MD
Publisher: Demos Medical Publishing
ISBN: 1933864753
Category : Medical
Languages : en
Pages : 163
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Book Description
A practical guide to the clinical use of serum and urine electrophoresis and also includes coverage of immunofixation electrophoresis. These techniques are essential in the accurate identification of monoclonal gammopathies and the diagnosis of multiple myeloma and related disorders. Interpretation is often challenging even for the experienced practitioner. Throughout the book the emphasis is on indications and practical aspects of interpreting test results. Particular attention is paid to differentiating false negative and false positive test results. The text provides clear, practical discussions extensively supported by representative images to guide the reader to accurate identification of specimens.
Author: Hillard M. Lazarus
Publisher: Springer Science & Business Media
ISBN: 1597454788
Category : Medical
Languages : en
Pages : 881
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Book Description
Since the original publication of Allogeneic Stem Cell Transplantation: Clinical Research and Practice, Allogeneic hematopoietic stem cell transplantation (HSC) has undergone several fast-paced changes. In this second edition, the editors have focused on topics relevant to evolving knowledge in the field in order to better guide clinicians in decision-making and management of their patients, as well as help lead laboratory investigators in new directions emanating from clinical observations. Some of the most respected clinicians and scientists in this discipline have responded to the recent advances in the field by providing state-of-the-art discussions addressing these topics in the second edition. The text covers the scope of human genomic variation, the methods of HLA typing and interpretation of high-resolution HLA results. Comprehensive and up-to-date, Allogeneic Stem Cell Transplantation: Clinical Research and Practice, Second Edition offers concise advice on today's best clinical practice and will be of significant benefit to all clinicians and researchers in allogeneic HSC transplantation.
