Mycobacterium Tuberculosis Pili (MTP) Modulates Pathogen and Host Metabolomic Changes in an A549 Epithelial Cell Model of Infection

Mycobacterium Tuberculosis Pili (MTP) Modulates Pathogen and Host Metabolomic Changes in an A549 Epithelial Cell Model of Infection PDF Author: Kajal Soulakshana Reedoy
Publisher:
ISBN:
Category : Epithelial cells
Languages : en
Pages : 256

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Book Description

Mycobacterium Tuberculosis Pili (MTP) Modulates Pathogen and Host Metabolomic Changes in an A549 Epithelial Cell Model of Infection

Mycobacterium Tuberculosis Pili (MTP) Modulates Pathogen and Host Metabolomic Changes in an A549 Epithelial Cell Model of Infection PDF Author: Kajal Soulakshana Reedoy
Publisher:
ISBN:
Category : Epithelial cells
Languages : en
Pages : 256

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Book Description


Pili in Mycobacterium Tuberculosis

Pili in Mycobacterium Tuberculosis PDF Author: Ali Akbar Velayati
Publisher: Elsevier
ISBN: 0443217130
Category : Science
Languages : en
Pages : 341

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Book Description
Pili in Mycobacterium Tuberculosis: Structure, Function, and Therapeutic Advances discusses the types of pili produced by the tuberculosis-causing bacterium, Mycobacterium tuberculosis (MTBC. The book examines the structure of pili shown under electron and atomic force microscopy and by using whole genome sequencing, outlines the importance of pili in mycobacterium tuberculosis. It also explores the role of pili in bacteria-host interactions and in drug development and delivery. Pili in Mycobacterium Tuberculosis opens with an overview of the structure, synthesis, and function of pili in bacteria. This includes taxonomy and the role of pili in diseases. The book also examines the preparation of Mycobacterium tuberculosis for electronic and atomic microscopy and looks at the different life cycles and susceptibility patterns of MTBC. It does on to discuss the expression and function of pili using whole genome sequencing and PCR-based methods and delves into bacteria host interactions. Lastly, it explores the development of new drugs and its delivery by pili. • Covers the structure, synthesis, and function of pili produced by the tuberculosis-causing bacterium, MTB• Introduces seven types of pili in MTB• Explains the mechanism of bacteria–host attachment and importance of this phenomena in MTB pili and other bacteria• Emphasizes the use of advances techniques to study and investigate the TB-bacilli and its interaction with host cells

Recent Advances and Future Perspectives of Microbial Metabolites

Recent Advances and Future Perspectives of Microbial Metabolites PDF Author: Surajit de Mandal
Publisher: Elsevier
ISBN: 032390114X
Category : Science
Languages : en
Pages : 358

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Book Description
Recent Advances and Future Perspectives of Microbial Metabolites: Applications in Biomedicine sheds new light on various applications of microbial metabolites in the biomedical sector. The purpose of this book is to integrate the latest research advancements on the application of microbial metabolites in the medical industry into a single platform. In 10 chapters, the significance of biomedical applications and future therapeutic applications of microbial metabolites in human health are highlighted. Several chapters are dedicated to the role of microbial metabolites in precision medicine like the impact of the activities of microbial metabolites in antitumor and antidiabetic agents and immunosuppressive activities. It also provides a roadmap for drugs discovery based on antimicrobial products and the effect of microbial metabolites on humans' health and the immune system. The book finalizes with a chapter on the use of microbial metabolites in OMICS technology. Recent Advances and Future Perspectives of Microbial Metabolites: Applications in Biomedicine targets researchers from both academia and industry, professors, and graduate students from microbiology, molecular biology, biotechnology, and immunology. - Highlights various microbial metabolites and their application in the biomedical sector - Illustrates the application of microbial metabolites as potential therapeutic agents - Convenient for buyers and readers to understand the basics with advanced information of microbial metabolites

Nutraceuticals in Veterinary Medicine

Nutraceuticals in Veterinary Medicine PDF Author: Ramesh C. Gupta
Publisher: Springer
ISBN: 3030046249
Category : Science
Languages : en
Pages : 877

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Book Description
This unique work compiles the latest knowledge around veterinary nutraceuticals, commonly referred to as dietary supplements, from ingredients to final products in a single source. More than sixty chapters organized in seven sections collate all related aspects of nutraceutical research in animal health and disease, among them many novel topics: common nutraceutical ingredients (Section-I), prebiotics, probiotics, synbiotics, enzymes and antibacterial alternatives (Section-II), applications of nutraceuticals in prevention and treatment of various diseases such as arthritis, periodontitis, diabetes, cognitive dysfunctions, mastitis, wounds, immune disorders, and cancer (Section-III), utilization of nutraceuticals in specific animal species (Section-IV), safety and toxicity evaluation of nutraceuticals and functional foods (Section-V), recent trends in nutraceutical research and product development (Section-VI), as well as regulatory aspects for nutraceuticals (Section-VII). The future of nutraceuticals and functional foods in veterinary medicine seems bright, as novel nutraceuticals will emerge and new uses of old agents will be discovered. International contributors to this book cover a variety of specialties in veterinary medicine, pharmacology, pharmacognosy, toxicology, chemistry, medicinal chemistry, biochemistry, physiology, nutrition, drug development, regulatory frameworks, and the nutraceutical industry. This is a highly informative and carefully presented book, providing scientific insight for academia, veterinarians, governmental and regulatory agencies with an interest in animal nutrition, complementary veterinary medicine, nutraceutical product development and research.

Microbial Metabolomics

Microbial Metabolomics PDF Author: Edward E.K. Baidoo
Publisher: Humana
ISBN: 9781493987566
Category : Science
Languages : en
Pages : 0

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Book Description
This detailed volume includes protocols that represent the breadth of microbial metabolomics approaches to both large-scale and small-scale experiments with intention of highlighting techniques that can be used for applications ranging from environmental microbiology to human disease. Utilizing mass spectrometry as their primary measurement tool, the chapters explore microbial metabolomics, metabolism and microbial physiology, metabolite sample preparation, current analytical techniques used to profile primary and secondary metabolites and lipids, as well as establishing data analysis workflows for targeted metabolomics, untargeted metabolomics, analysis of metabolic fluxes, and genome-scale models. Written for the highly successful Methods in Molecular Biology series, chapters include introduction to their respective topics, lists of the necessary materials and reagents, step-by-step readily reproducible protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Microbial Metabolomics: Methods and Protocols serves as an ideal reference for both novice and advanced users and can be adapted to similar analytical platforms or customized to suit the needs of the researcher.

Nutraceuticals

Nutraceuticals PDF Author: Ramesh C Gupta
Publisher: Academic Press
ISBN: 0128212462
Category : Medical
Languages : en
Pages : 1397

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Book Description
Nutraceuticals: Efficacy, Safety and Toxicity, Second Edition, brings together everything that is currently known about nutraceuticals and their potential toxic effects. The book introduces readers to nutraceuticals, herbal medicines, Ayurvedic medicines, prebiotics, probiotics, adaptogens, and their uses and specific applications. This essential reference discusses the mechanism of action for the judicious use of these nutraceuticals and the best tools for their evaluation before detailing the safety and toxicity of nutraceuticals and interactions with other therapeutic drugs. Finally, and crucially, regulatory aspects from around the world are covered. Completely revised and updated, this updated edition provides toxicologists, pharmacologists, pharmaceutical scientists, and those interested in medicinal plants and natural products with a comprehensive overview of the most effective tools upon which to evaluate the safety and toxicity of nutraceuticals, prebiotics, probiotics and alternative medicines. - Presents a completely revised and updated resource on the impact of nutraceuticals and various disease states such as diabetes and ophthalmic and dermal diseases - Grants an overview of the current state-of-the-science of nutraceuticals, their use and applications, and known adverse effects - Provides effective tools to evaluate the potential toxicity of any nutraceutical - Includes details of regulatory issues as written by international experts

C-Type Lectins in Immune Homeostasis

C-Type Lectins in Immune Homeostasis PDF Author: Sho Yamasaki
Publisher: Springer
ISBN: 9783030622398
Category : Medical
Languages : en
Pages : 203

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Book Description
This book focuses on C-type lectin receptors, a newly emerging family of pattern-recognition receptors (PRRs) and a crucial part of the human innate immune system. Above all, the authors highlight these receptors’ role in the recognition of pathogen-associated molecular patterns (PAMPs) and damage-associated molecular patterns (DAMPs) – one of the first steps in responding to foreign and potentially dangerous structures in the human body. The respective chapters chiefly examine various C-type lectin receptors, their corresponding ligands, and signalling. In addition to offering immunologists and clinicians important insights from the latest research, they may also provide novel points of departure for future drug development.

Translocator Protein (TSPO)

Translocator Protein (TSPO) PDF Author: Giovanni Natile
Publisher: MDPI
ISBN: 3038427578
Category : Science
Languages : en
Pages : 177

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Book Description
This book is a printed edition of the Special Issue "Translocator Protein (TSPO)" that was published in IJMS

Research of Pathogenesis and Novel Therapeutics in Arthritis

Research of Pathogenesis and Novel Therapeutics in Arthritis PDF Author: Chih-Hsin Tang
Publisher: MDPI
ISBN: 3038970654
Category : Medical
Languages : en
Pages : 366

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Book Description
Arthritis has a high prevalence globally and includes over 100 different types, the most common of which are rheumatoid arthritis, osteoarthritis, psoriatic arthritis, and inflammatory arthritis. The exact etiology of arthritis remains unclear and no cure exists. Anti-inflammatory drugs are commonly used in the treatment of arthritis but are associated with significant side effects. Novel modes of therapy and additional prognostic biomarkers are urgently needed for arthritis patients. This book summarizes and discusses the global picture of the current understanding of arthritis.

Pili and Flagella

Pili and Flagella PDF Author: Ken F. Jarrell
Publisher: Caister Academic Press Limited
ISBN: 9781904455486
Category : Science
Languages : en
Pages : 0

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Book Description
This book, the first for many years on this important topic, brings together some of the top scientists in the field and describes the current knowledge and latest research on prokaryotic pili and flagella. The emphasis of the chapters is on the molecular