Mycobacterial Dormancy, Culturability, and Resuscitation: State-of-the-art, Challenges, and Future Prospects PDF Download
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Author: Elena G. Salina
Publisher: Frontiers Media SA
ISBN: 2832523676
Category : Science
Languages : en
Pages : 133
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Book Description
Author: Elena G. Salina
Publisher: Frontiers Media SA
ISBN: 2832523676
Category : Science
Languages : en
Pages : 133
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Book Description
Author: National Academies of Sciences, Engineering, and Medicine
Publisher: National Academies Press
ISBN: 030949382X
Category : Medical
Languages : en
Pages : 291
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Book Description
Legionnaires' disease, a pneumonia caused by the Legionella bacterium, is the leading cause of reported waterborne disease outbreaks in the United States. Legionella occur naturally in water from many different environmental sources, but grow rapidly in the warm, stagnant conditions that can be found in engineered water systems such as cooling towers, building plumbing, and hot tubs. Humans are primarily exposed to Legionella through inhalation of contaminated aerosols into the respiratory system. Legionnaires' disease can be fatal, with between 3 and 33 percent of Legionella infections leading to death, and studies show the incidence of Legionnaires' disease in the United States increased five-fold from 2000 to 2017. Management of Legionella in Water Systems reviews the state of science on Legionella contamination of water systems, specifically the ecology and diagnosis. This report explores the process of transmission via water systems, quantification, prevention and control, and policy and training issues that affect the incidence of Legionnaires' disease. It also analyzes existing knowledge gaps and recommends research priorities moving forward.
Author: Seyed Ehtesham Hasnain
Publisher: Springer
ISBN: 9789813294127
Category : Medical
Languages : en
Pages : 514
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Book Description
This book reviews recent advances in the molecular and infection biology, pathology, and molecular epidemiology of Mycobacterium tuberculosis, as well as the identification and validation of novel molecular drug targets for the treatment of this mycobacterial disease. Despite being completely curable, tuberculosis is still one of the leading global causes of death. M. tuberculosis, the causative organism – one of the smartest pathogens known – adopts highly intelligent strategies for survival and pathogenesis. Presenting a wealth of information on the molecular infection biology of M. tuberculosis, as well as nontuberculous mycobacteria (NTM), the book provides an overview of the functional role of the PE/PPE group of proteins, which is exclusive to the genus Mycobacteria, of host-pathogen interactions, and virulence. It also explores the pathogenesis of the infection, pathology, epidemiology, and diagnosis of NTM. Finally it discusses current and novel approaches in vaccine development against tuberculosis, including the role of nanotechnology. With state-of-the-art contributions from experts in the respective domains, this book is an informative resource for practitioners as well as medical postgraduate students and researchers.
Author: Dick van der Kooij
Publisher: IWA Publishing
ISBN: 1780400403
Category : Science
Languages : en
Pages : 484
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Book Description
Maintaining the microbial quality in distribution systems and connected installations remains a challenge for the water supply companies all over the world, despite many years of research. This book identifies the main concerns and knowledge gaps related to regrowth and stimulates cooperation in future research. Microbial Growth in Drinking Water Supplies provides an overview of the regrowth issue in different countries and the water quality problems related to regrowth. The book assesses the causes of regrowth in drinking water and the prevention of regrowth by water treatment and distribution. Editors: Dirk van der Kooij and Paul W.J.J. van der Wielen, KWR Watercycle Research Institute, The Netherlands
Author: Kenneth C. Fugelsang
Publisher: Рипол Классик
ISBN: 5881474686
Category : History
Languages : en
Pages : 415
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Book Description
Author: Gareth M. Evans
Publisher: John Wiley & Sons
ISBN: 0470856769
Category : Science
Languages : en
Pages : 302
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Book Description
The application of biologically-engineered solutions toenvironmental problems has become far more readily acceptable andwidely understood. However there remains some uncertainty amongstpractitioners regarding how and where the microscopic, functionallevel fits into the macroscopic, practical applications. It isprecisely this gap which the book sets out to fill. Dividing the topic into logical strands covering pollution,waste and manufacturing, the book examines the potential forbiotechnological interventions and current industrial practice,with the underpinning microbial techniques and methods described,in context, against this background. Each chapter is supported by located case studies from a rangeof industries and countries to provide readers with an overview ofthe range of applications for biotechnology. Essential reading for undergraduates and Masters studentstaking modules in Biotechnology or Pollution Control as part ofEnvironmental Science, Environmental Management or EnvironmentalBiology programmes. It is also suitable for professionals involvedwith water, waste management and pollution control.
Author: Jeffrey D. Cirillo
Publisher: Springer Nature
ISBN: 3030253813
Category : Medical
Languages : en
Pages : 255
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Book Description
This book summarizes the progress in studies of tuberculosis host-pathogen interactions from several perspectives: molecular microbiology, immunology, animal models, clinical studies, epidemiology, and drug discovery. Tuberculosis (TB) remains a severe global public health problem. Complex interactions between environmental, microbial and host factors lead to clinically relevant infections. Studies on bacterial virulence, host-genetic, and immunological factors contributing to the susceptibility to TB provide an ever-growing foundation of knowledge that is critical to finding new interventions. Studies of immune mechanisms against M. tuberculosis infection have identified immunological markers associated with specific phenotypes in the host, providing insight into how they may be used to augment current treatment strategies. Recent advances in diagnosis, therapeutics and vaccines, as well as basic-research oriented studies have shed light on the development of new directions for prevention, treatment and control of TB. Improved understanding of the interplay between the bacterium and host is a key component of reducing incidence worldwide.
Author: Colin B. Munn
Publisher: CRC Press
ISBN: 0429590423
Category : Science
Languages : en
Pages : 636
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Book Description
The third edition of this bestselling text has been rigorously updated to reflect major new discoveries and concepts since 2011, especially progress due to extensive application of high-throughput sequencing, single cell genomics and analysis of large datasets. Significant advances in understanding the diversity and evolution of bacteria, archaea, fungi, protists, and viruses are discussed and their importance in marine processes is explored in detail. Now in full colour throughout, all chapters have been significantly expanded, with many new diagrams, illustrations and boxes to aid students’ interest and understanding. Novel pedagogy is designed to encourage students to explore current high-profile research topics. Examples include the impacts of rising CO2 levels on microbial community structure and ocean processes, interactions of microbes with plastic pollution, symbiotic interactions, and emerging diseases of marine life. This is the only textbook addressing such a broad range of topics in the specific area of marine microbiology, now a core topic within broader Marine Science degrees. A Companion Website provides additional online resources for instructors and students, including a summary of key concepts and terminology for each chapter, links to further resources, and flashcards to aid self-assessment.
Author: S. J. Pirt
Publisher: Wiley-Blackwell
ISBN: 9780632014552
Category : Microbiology
Languages : en
Pages : 274
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Book Description
Author: Slava S. Epstein
Publisher: Springer Science & Business Media
ISBN: 3540854657
Category : Medical
Languages : en
Pages : 215
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Book Description
In 1898, an Austrian microbiologist Heinrich Winterberg made a curious observation: the number of microbial cells in his samples did not match the number of colonies formed on nutrient media (Winterberg 1898). About a decade later, J. Amann qu- tified this mismatch, which turned out to be surprisingly large, with non-growing cells outnumbering the cultivable ones almost 150 times (Amann 1911). These papers signify some of the earliest steps towards the discovery of an important phenomenon known today as the Great Plate Count Anomaly (Staley and Konopka 1985). Note how early in the history of microbiology these steps were taken. Detecting the Anomaly almost certainly required the Plate. If so, then the period from 1881 to 1887, the years when Robert Koch and Petri introduced their key inventions (Koch 1881; Petri 1887), sets the earliest boundary for the discovery, which is remarkably close to the 1898 observations by H. Winterberg. Celebrating its 111th anniversary, the Great Plate Count Anomaly today is arguably the oldest unresolved microbiological phenomenon. In the years to follow, the Anomaly was repeatedly confirmed by all microb- logists who cared to compare the cell count in the inoculum to the colony count in the Petri dish (cf., Cholodny 1929; Butkevich 1932; Butkevich and Butkevich 1936). By mid-century, the remarkable difference between the two counts became a universally recognized phenomenon, acknowledged by several classics of the time (Waksman and Hotchkiss 1937; ZoBell 1946; Jannasch and Jones 1959).
